Masiku ano, imodzi mwa mankhwala odziwika bwino ndi Liraglutide pochiza matenda a shuga a 2.
Zachidziwikire, m'dziko lathu lapeza kutchuka posachedwa. Izi zisanachitike, zidagwiritsidwa ntchito kwambiri ku United States, komwe zakhala zikugwiritsidwa ntchito kuyambira zikwi ziwiri ndi zisanu ndi zinayi. Cholinga chake chachikulu ndikuchiza odwala kwambiri. Koma kupatula izi, imagwiritsidwanso ntchito pochiza matenda ashuga, ndipo monga mukudziwa, ndi matenda a shuga 2, vuto ngati kunenepa kwambiri ndilofala kwambiri.
Kugwiritsa ntchito kwambiri mankhwalawa kumatheka chifukwa cha zinthu zapadera zomwe zimapanga kapangidwe kake. Mwakutero, ndi Lyraglutide. Ndi mndandanda wokwanira wa enzyme ya munthu, yomwe ili ndi dzina loti glucagon-like peptide-1, yomwe imakhala ndi mphamvu yayitali.
Chipangizochi ndi chithunzi chopanga cha munthu, motero chimagwira ntchito yake mthupi, chifukwa sikuti chimasiyanitsa komwe kuli analogue komwe kuli komanso komwe enzyme ili.
Mankhwalawa amagulitsidwa m'njira yothetsera jakisoni.
Ngati tikulankhula za kuchuluka kwa mankhwalawa, ndiye choyamba, mtengo wake umatengera mlingo wa chinthu chachikulu. Mtengo umasiyana kuchokera ku 9000 mpaka 27000 rubles. Kuti mumvetsetse kuchuluka kwa mankhwalawa omwe muyenera kugula, muyenera kuphunzira kufotokozeratu za mankhwalawo ndipo, inde, kuonana ndi dokotala.
Pharmacological zochita za mankhwala
Monga tanena kale, chida ichi ndi mankhwala abwino kwambiri opatsirana, komanso imathandizira kuchepetsa kuchepa kwa thupi, komwe kumakhudza kwambiri odwala omwe amapezeka ndi matenda a shuga 2.
Izi ndizotheka chifukwa choti kulowa m'magazi a wodwalayo, mankhwalawo amakulitsa kwambiri ma peptides omwe ali mthupi la munthu aliyense. Ndi chochita ichi chomwe chimathandizira kapangidwe kake ka kapamba ndi kukhazikitsa njira yopanga insulini.
Chifukwa cha njirayi, kuchuluka kwa shuga komwe kumakhala m'magazi a wodwalayo kumatsitsidwa kufikira mulingo womwe mukufuna. Chifukwa chake, zinthu zonse zofunikira zomwe zimalowa m'thupi la wodwalayo limodzi ndi chakudya zimamwa bwino. Zachidziwikire, chifukwa, kulemera kwa wodwalayo kumasinthasintha komanso kusadya kumachepetsa kwambiri.
Koma, monga mankhwala ena aliwonse, Liraglutid amayenera kumwedwa mosamala malinga ndi zomwe adokotala amapeza. Tiyerekeze kuti simuyenera kungogwiritsa ntchito chabe kuti muchepetse kunenepa. Njira yabwino kwambiri yothetsera vutoli ndikugwiritsa ntchito mankhwalawa pali mitundu iwiri ya ashuga, yomwe imayendera limodzi ndi kunenepa kwambiri.
Mankhwala a Liraglutide atha kutengedwa ngati mukufuna kubwezeretsa index ya glycemic.
Koma madotolo amasiyananso zizindikilo zotere zomwe zikusonyeza kuti wodwalayo samalimbikitsidwa kupereka mankhwala omwe atchulidwawa. Izi ndi:
- thupi lawo siligwirizana mbali iliyonse ya mankhwala;
- kuzindikira kwa matenda a shuga a mtundu woyamba;
- matenda aliwonse a chiwindi kapena impso;
- kulephera kwa mtima kwa digiri yachitatu kapena yachinayi;
- yotupa njira m'matumbo;
- kukhalapo kwa neoplasm pa chithokomiro cha chithokomiro;
- kukhalapo kwa angapo endocrine neoplasia;
- nthawi ya pakati mwa mayi, komanso yoyamwitsa.
Mukumbukiranso kuti mankhwalawa sangatengedwe ndi jakisoni wa insulin kapena mankhwala ena aliwonse omwe ali ndi zigawo zomwezo. Madokotala samalangizabe kugwiritsa ntchito mankhwalawa kwa odwala azaka zopitilira 75, komanso kwa iwo omwe amapezeka ndi kapamba.
Zotsatira zoyipa kuchokera pakumwa mankhwala
Pokhudzana ndi chidziwitso chomwe chatchulidwa pamwambapa, zikuwonekeratu kuti musanayambe mankhwala ndi mankhwalawa, muyenera kufotokozera ngati mankhwalawa angawononge thanzi la wodwalayo. Mwachitsanzo, ngati pali zovuta zina ndi mtima wamtima, ndiye kuti kupezeka ndi izi ndi njira yotsutsana ndi kugwiritsa ntchito mankhwalawa.
Tisaiwale kuti kugwiritsa ntchito njira zingapo zochepetsera thupi ndizoletsedwa. Ana ochepera zaka 18 nawonso ali pachiwopsezo; amalephereranso kupatsidwa mankhwala ndi mankhwalawa.
Pali malangizo ogwiritsira ntchito mankhwalawa, momwe chidziwitso chonsechi chikufotokozedwera.
Ngati tirikunena za mavuto omwe amapezeka kawirikawiri chifukwa chogwiritsa ntchito mankhwalawa, ndiye kuti pali zovuta zina zam'mimba. Pafupifupi theka la milandu yomwe wodwalayo amakumana nayo, amayamba kumva kupweteka kwambiri komanso kusanza.
Wodwala aliyense wachisanu yemwe amathandizidwa ndimankhwala amadandaula za kudzimbidwa, makamaka, matenda otseguka m'mimba, kapena, kudzimbidwa kwambiri.
Zina zoyipa zimaphatikizira kuwoneka ngati kumva kutopa kwambiri kapena kutopa.
Dziwani kuti nthawi zina mikhalidwe imatha,, mukamwa mankhwala ochuluka kwambiri, shuga wa wodwalayo amatsika kwambiri.
Potere, uchi amuthandiza. Kwenikweni spoonful uchi ndi glucose magazi ndi yachibadwa.
Malangizo ogwiritsira ntchito mankhwalawa
Odwala ambiri ali ndi chidwi ndi funso loti Lyraglutide ili yothandiza bwanji.
Pankhaniyi, zonse zimatengera Mlingo womwe wodwala amatenga, ngati atasankhidwa molondola, ndiye kuti kugwiritsa ntchito bwino mankhwalawo kudzakhala kwakukulu.
Mwachitsanzo, ngati timalankhula za mankhwala omwe amagulitsidwa mu mtundu wa Saxenda, mlingo ungakhale kuchokera pa 0.6 mg mpaka 3.
Pankhaniyi, zilibe kanthu kuti mankhwalawa amwedwa liti, kugwira ntchito kwake sikusintha kuchokera ku izi.
Poyamba, mlingo umatha kukhala wofanana ndi zero pafupifupi magawo asanu ndi limodzi a mg, ndipo mlingo uliwonse wotsatira umakulitsidwa. Pafupifupi sabata lachisanu, wodwalayo akulimbikitsidwa kuti amwe mankhwala 3 mg, mlingo wotere umapitilizidwa mpaka kumapeto kwa chithandizo.
Ngati tikulankhula za mtundu wina wa mankhwala womwe umaphatikizira kuyambitsa jakisoni wa chinthu, ndiye kuti mankhwalawo amalowetsedwa mu ntchafu, m'mimba kapena phewa.
Dziwani kuti kuchuluka kwa mankhwalawa komanso kuchuluka kwa chithandizo chamankhwala zitha kuperekedwa ndi dokotala. Kugwiritsa ntchito mankhwalawa payekha kungayambitse vuto lakudwala.
Nthawi zina mikhalidwe imatha kuchitika pamene hypoglycemia ikhoza kuyamba mwa munthu kuyambira pa liraglutide kwa nthawi yayitali. Pankhaniyi, muyenera kugwiritsa ntchito uchi nthawi yomweyo.
Analogi ndi mtengo
Chifukwa chakuti mankhwalawa amalekanitsidwa mwa odwala omwe amadalira insulin, madokotala ena amalimbikitsa kulingalira za mankhwala osakanikirana ndi mankhwala. Mwachitsanzo, pankhaniyi, Reduxine akhoza kukhala wothandiza kwambiri.
Ma kapisozi awa ndi othandiza kwambiri pakuchepetsa thupi, komanso mwanjira ina kuwatengera kuti alandire mtundu 2 wa matenda a shuga komanso matenda a insulin. Mwa njira, ndi awa omwe amadwala omwe nthawi zambiri amakhala limodzi ndi onenepa. Kuphatikizanso kwina kwa mankhwalawo ndi mtengo wake wovomerezeka; saposa ma ruble mazana awiri.
Lipase inhibitor imagwiritsidwanso ntchito nthawi zambiri. Mndandanda wa mankhwala omwe ali ndi zinthu zotere ndi monga mapiritsi osiyanasiyana, mwachitsanzo, Orsogen kapena Xenical. Ali ndi katundu wofanana omwe wafotokozedwa pamwambapa.
Dziwani kuti ma analogu sangasankhidwe pawokha. Dokotala wokha ndi amene angathe kusankha kuti athe kupereka mankhwala kwa wodwala aliyense kapena ngati kuli bwino kungoyang'ana pa mankhwala omwe adasankhidwa kale.
Palinso mitundu ina yofananira yomwe ingagwiritsidwenso ntchito pothana ndi kulemera kwambiri komwe kumawonekera m'matenda a shuga. Mwachitsanzo, Novonorm, Baeta kapena Liksumiya. Ngati tizingolankhula za mtengo wa ndalamazi, ndiye kuti mankhwala oyamba amakhala otsika mtengo kwambiri, amatenga pafupifupi ma ruble 250.
Ndemanga za Chithandizo
Monga tafotokozera pamwambapa, odwala ambiri amawona kugwira bwino ntchito kwa mankhwalawa, omwe amagwiritsidwa ntchito pa matenda a shuga, omwe amaphatikizidwa ndi kunenepa kwambiri. Chiwerengerochi ndi pafupifupi 80% ya onse omwe agwiritsa ntchito mankhwalawa.
Odwala ena, akugawana zomwe akudziwa kale chithandizo, adawonetsa kuti nthawi zina amakhala ndi zizindikiro zoyambirira za hypoglycemia. Izi zimachitika kawirikawiri pamene mlingo wa mankhwalawa womwe wodwala amatenga umakhala wokwera kwambiri kuposa momwe dokotala wakupangira. Poterepa, uchi kapena maswiti wamba angathandize. Koma, zoona, uchi ndi wathanzi.
Koma ziribe kanthu momwe mankhwalawa amapereka, sangatengeredwe mosalekeza.
Pali mtundu wa mankhwala omwe angafalikire kwa wodwala aliyense payekhapayekha. Ndi chifukwa ichi kuti zitheka kuthetsa mavuto ambiri ndi kunenepa kwambiri ndikuchepetsa kwambiri kuchuluka kwa shuga m'magazi.
Kutengera ndi zomwe tafotokozazi, zikuwonekeratu kuti kugwiritsa ntchito mankhwalawa kuyenera kuchitika pokhapokha atakambilana ndi dokotala ndipo, pokhapokha pakulimbikitsa kwake.
Ndi mapiritsi ati a kunenepa kwambiri a shuga omwe angagwiritsidwe ntchito anganene vidiyoyi munkhaniyi.
