Telzap ndi mankhwala omwe amachepetsa chiopsezo chokhala ndi matenda amtima. Kuchita bwino kwatsimikiziridwa m'mayesero azachipatala komanso machitidwe azachipatala.
Dzinalo Losayenerana
Dzinali Telmisartan limagwiritsidwa ntchito ngati sanali mayiko ena.
Telzap ndi mankhwala omwe amachepetsa chiopsezo chokhala ndi matenda amtima.
ATX
Nambala ya ATX C09CA07.
Kutulutsa mafomu ndi kapangidwe kake
Telzap 40 mg ipezeka mu mawonekedwe a mapiritsi, omwe ali ndi mawonekedwe a oblong biconvex. Mtundu wa mapiritsiwo ukhoza kukhala woyera kapena wachikasu. Mbali zonsezi zili pachiwopsezo.
Chofunikira chachikulu ndi telmisartan. Zomwe zili piritsi lililonse zimafikira 40 mg.
Malangizo othandizira amaphatikizapo zinthu izi:
- sorbitol;
- meglumine;
- magnesium wakuba;
- sodium hydroxide;
- povidone.
Zotsatira za pharmacological
The yogwira mankhwala telmisartan ali ndi mphamvu ya enieni angiotensin II receptor antagonists. Mukamwetsa, mankhwalawa amatha kuthamangitsa angiotensin II kuchokera pakulumikizana ndi receptor. Kuphatikiza apo, polankhula ndi receptor uyu, sikuti amangokhalira kukangana. Telmisartan imalumikizana ndi angiotensin II ATl receptors. Zomwe zimagwira sizikuwonetsa zofanana ndi AT2 receptor ndi zina.
Mothandizidwa ndi mankhwala m'magazi am'magazi, kuchuluka kwa aldosterone kumachepa. Nthawi yomweyo, ntchito za renin zimakhalabe pamlingo womwewo ndipo mayendedwe a ion satsekedwa.
Angiotensin-akatembenuza enzyme yomwe imathandizira kuwonongeka kwa bradykinin sikuletsa. Izi zimakuthandizani kuti muthane ndi chiopsezo cha zovuta zina monga kutsokomola.
Mukamagwiritsa ntchito mlingo wa 80 mg mu odwala, chiwopsezo cha angiotensin II chatsekedwa. Zotsatira zake zimatheka patadutsa maola atatu itatha yoyamba mlingo. Kuchitikaku kumatenga maola 24. Amamuwona ngati wothandiza kwa maola 48. Kudya mapiritsi pafupipafupi kwa masabata a 4-8 kumabweretsa zotsatira zabwino za antihypertensive.
Kugwiritsa ntchito kwa Telzap odwala omwe ali ndi matenda oopsa kwambiri kungachepetse kuthamanga kwa magazi kwa diastoli ndi systolic. Pakadali pano, kugunda kwa mtima sikusintha.
Mankhwalawa amagwiritsidwa ntchito pochiza matenda amtima. Okalamba odwala ndi pathologies a mtima dongosolo, mapiritsi anali ndi kuchepetsa kuchepetsa pafupipafupi:
- myocardial infarction;
- mikwingwirima;
- kufa chifukwa cha matenda amtima.
Pharmacokinetics
Pambuyo pakukonzekera pakamwa, mankhwalawa amatengeka mwachangu. Pafupifupi, bioavailability wake amafika 50%. Kudya kumachepetsa kuyamwa kwa mankhwalawa.
Telmisartan imamangiriza ndi alpha-1 acid glycoprotein, albin, ndi mapuloteni ena a plasma.
Metabolism imachitika panthawi yolumikizana ndi glucuronic acid. Pulogalamuyi ilibe zochitika zamankhwala. Kuchotsa kwazinthu kumachitika kudzera m'matumbo. Poterepa, thupi lathu limasintha mosasintha. 1% yokha ya chinthucho imapukutidwa kudzera mu impso.
Zizindikiro zogwiritsidwa ntchito
Telzap imalembedwa kwa odwala omwe ali ndi zotsatirazi:
- matenda oopsa;
- lembani matenda ashuga 2 mellitus (pamaso pa zotupa za ziwalo zozama);
- mtima matenda a atherothrombotic chiyambi (mndandanda wa matenda otere, sitiroko, mtima matenda, kuwonongeka kwa zotumphukira mitsempha).
Mapiritsi amathandizidwanso monga prophylactic ya matenda amtima kwa odwala omwe ali pachiwopsezo.
Contraindication
Mankhwala kwathunthu contra:
- ndi chidwi chowonjezeka pakapangidwe kazigawo kapena kagwiritsidwe kothandizira;
- ngati matenda opatsirana okhudza msempha;
- pa mimba ndi yoyamwitsa;
- ndi tsankho la munthu;
- ana ochepera zaka 18.
Ndi chisamaliro
Mu malangizo ogwiritsira ntchito, ma pathologies angapo amatchulidwa, omwe Telzap adayikidwa mosamala kwambiri moyang'aniridwa ndi dokotala:
- aimpso kuwonongeka;
- aimpso mtsempha wamagazi stenosis;
- Hyperkalemia
- hyponatremia;
- mitral kapena aortic valve stenosis;
- amachepetsa kuchuluka kwa magazi komwe kumachitika mutatha kupukusa, kusanza, kutsekula m'mimba, kapena kusowa kwa mchere mu chakudya;
- chachikulu hyperaldosteronism;
- kuchira pambuyo kupatsidwa impso;
- kulakwitsa kwa chiwindi (wofatsa pang'ono);
- kulephera kwamtima kwambiri;
- hypertrophic cardiomyopathy.
Muyenera kusamala mukamagwiritsa ntchito mapiritsi awa pochiza odwala a mtundu wa Negroid.
Momwe mungatenge telzap 40 mg
Mapiritsiwo adapangira pakamwa. Amameza osafuna kuthengo ndikusambitsidwa ndi kapu yamadzi. Monga mtundu wanthawi zonse wa mankhwala, tikulimbikitsidwa kuti mutenge piritsi limodzi la Telzap patsiku osatchulanso zakudya. Mlingo umatengera mawonekedwe a omwe apezeka ndi matendawa.
Pa matenda oopsa oopsa, mlingo woyambirira ndi piritsi limodzi 40 mg. Pokhapokha pakufunika kofunikira, mlingoyo ukhoza kuwonjezeka mpaka 80 mg.
Kugwiritsa ntchito ngati prophylactic kwa matenda amtima ali ndi njira ina. Pankhaniyi, mulingo woyenera kwambiri ndi 80 mg patsiku.
Chithandizo cha matenda ashuga
Mapiritsi a Telzap atsimikizira kuti ndi othandizira othandizira odwala ovuta a matenda a shuga 2. Anthu omwe amalandila mankhwala a hypoglycemic ayenera kuwunika miyezo yawo ya glycemia nthawi zonse. Nthawi zina, kukonza ma hypoglycemic wothandizira kapena insulin kumafunika.
Mapiritsi a Telzap atsimikizira kuti ndi othandizira othandizira odwala ovuta a matenda a shuga 2.
Zotsatira zoyipa
Mwa odwala ena, kutenga Telzap kumatha kubweretsa mawonekedwe owoneka bwino.
Matumbo
Kuchokera m'mimba, kupukusa m'mimba, kupweteka kwam'mimba, kusanza, kugona ndi kukomoka kumachitika kawirikawiri kuposa ena. Mavuto amakomedwe, kusapeza bwino mu gawo la epigastric, mucosa wowuma pamlomo wamkati samadziwika kwambiri.
Hematopoietic ziwalo
Pali umboni wa kakulidwe ka thrombocytopenia, eosinophilia ndi hemoglobin wotsika.
Pakati mantha dongosolo
Odwala ena amadandaula za kusowa tulo, kukhumudwa, nkhawa zambiri. Nthawi zina, amakomoka.
Kuchokera kwamikodzo
Mwa zina zoyipa zomwe zimayambitsa matenda a impso. Zina mwa izi ndi kulephera kwa aimpso.
Kuchokera ku kupuma
Dyspnea ndi chifuwa sizimachitika kawirikawiri. Pafupipafupi, pamakhala matenda amkati wamapapo.
Pa khungu
Mndandanda wazotsatira zoyenera zotchedwa hyperhidrosis, kuyabwa pakhungu, zotupa. Eczema, angioedema, erythema, poizoni wakhungu ndi mankhwala osokoneza bongo samapezeka kawirikawiri.
Kuchokera ku genitourinary system
Mwa azimayi, matenda otupa a kubereka amatha kuchitika, nthawi zina, vuto lakusamba kwa msambo limawonedwa. Mwa amuna, kukanika kwa erectile ndikotheka.
Kuchokera pamtima
Matenda amtima sakonda kuyankha zochitika zoyipa ndi chithandizo cha Telzap. Pakadali pano, odwala ndi otheka:
- kukomoka chifukwa cha hypotension;
- kuchepa kapena kuchuluka kwa kugunda kwa mtima;
- Kuchepetsa kuthamanga kwa magazi ndikusintha kwa malo amthupi.
Dongosolo la Endocrine
Kugwiritsa ntchito mankhwalawa kungayambitse kuchepa kwa shuga m'magazi ndi metabolic acidosis.
Pa mbali ya chiwindi ndi biliary thirakiti
Mavuto a ndulu ndi chiwindi ndi osowa kwambiri.
Matupi omaliza
Pazonse zomwe sizingachitike, izi ndizotheka:
- rhinitis;
- zotupa pakhungu;
- laryngeal edema;
- Edema wa Quincke.
Malangizo apadera
Zotsatira zoyipa zilizonse, siyani kumwa mankhwalawo ndipo pitani kuchipatala. Kuchepetsa kwambiri kuthamanga kwa magazi kumayambitsa stroke, kugunda kwamtima ndi zotsatira zakupha.
Kuyenderana ndi mowa
Kumwa mowa ndizoletsedwa panthawi ya chithandizo ndi Telzap. Kugwirizana kwa mankhwalawa ndi ethanol kumayambitsa kuchepa kwa kuthamanga kwa magazi, komwe kungayambitse kupuma.
Kumwa mowa ndizoletsedwa panthawi ya chithandizo ndi Telzap.
Zokhudza mphamvu pakuwongolera njira
Palibe malangizo apadera pankhaniyi, komabe, kugwiritsa ntchito mankhwalawa kumatha kuyambitsa mavuto (kukomoka, chizungulire, kugona). Pokhala ndi izi m'maganizo, muyendetse mosamala.
Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere
Mankhwala, palibe chidziwitso cha mankhwala a mwana wosabadwayo. Kafukufuku wachipatala cha nyama adawoneka kuti ali ndi poizoni pa mwana wosabadwayo. Pachifukwa ichi, mankhwala ena amathandizidwa kuti azitha amayi apakati.
Mu 2nd ndi 3 trimester, kugwiritsa ntchito mankhwala kuchokera pagulu la angiotensin otsutsana kungayambitse chiwindi, impso, kuchepera kwa msana kwa chigaza, oligohydramnios.
Panthawi yovomerezeka, kuikidwa kwa Telzap ndikuloledwa. Kupanda kutero, kuyamwitsa kuyenera kusokonezedwa.
Kupangira Telzap 40 mg kwa ana
Ana osakwana zaka 18 ali oletsedwa kumwa mapiritsi okhala ndi telmisartan.
Gwiritsani ntchito mu ukalamba
Odwala omwe ali ndi zaka zopitilira 70 safuna kusintha kwa mlingo. Kupatula pali milandu yokhala ndi impso kapena chiwindi.
Odwala omwe ali ndi zaka zopitilira 70 safuna kusintha kwa mlingo.
The ntchito aimpso kuwonongeka
Mukuwonongeka kwambiri kwa aimpso, mlingo wosapitilira 20 mg wa mankhwala patsiku uyenera kugwiritsidwa ntchito.
Gwiritsani ntchito ntchito yolakwika ya chiwindi
M'matenda akulu a chiwindi, Telzap sigwiritsidwa ntchito.
Bongo
Ngati mulingo wovomerezeka utaperekedwa, zizindikiro zotsatirazi zimachitika:
- kutsika kwa mtima;
- Chizungulire
- kuchepa kwakukulu kwa kuthamanga kwa magazi;
- Zizindikiro zakulephera kwa impso.
Kuchita ndi mankhwala ena
Telzap nthawi zambiri imagwiritsidwa ntchito ngati gawo la chithandizo chovuta, motero muyenera kuganizira momwe mapiritsi amaphatikizira ndi mankhwala ena.
Kuphatikiza kophatikizidwa
Odwala omwe ali ndi matenda a shuga a mtundu wachiwiri samaloledwa kutenga telmisartan ndi ma ACE enhibitors nthawi imodzi. Nthawi zambiri, izi zimayambitsa hypoglycemia.
Osavomerezeka kuphatikiza
Mankhwala osavomerezeka kuti agwiritse ntchito:
- heparin;
- immunosuppressants;
- mankhwala osapweteka a antiidal;
- zakudya zopezeka potaziyamu;
- potaziyamu osungira okodzetsa;
- amatanthauza momwe hydrochlorothiazide imakhalamo.
Kuphatikiza komwe kumafunikira kusamala
Kuwunika pafupipafupi zamankhwala ndikusintha kwa mankhwalawa kungafunike pogwiritsa ntchito telmisartan ndi mankhwala otsatirawa:
- Asipirin;
- digoxin;
- furosemide;
- mankhwala a lithiamu;
- barbiturates;
- corticosteroids.
Analogi
M'malo Telzap ndi mankhwala ofanana zikuchokera ndi monga:
- Telpres
- Mikardis;
- Telsartan;
- Lozap.
Miyezo yopuma ya Telzap 40 mg kuchokera kuma pharmacies
Telzap itha kugulidwa ku pharmacy ndi mankhwala.
Kodi ndingagule popanda kulandira mankhwala?
Mankhwala m'gululi saloledwa kugulitsa popanda mankhwala.
Mtengo
Mtengo wamapiritsi ndi ma ruble 450-500.
Zosungidwa zamankhwala
Sungani mankhwalawo pa kutentha osaposa + 25 ° C.
Tsiku lotha ntchito
Kutengera ndi momwe zimasungidwira, mapiritsiwa amakhala ndi alumali zaka 2.
Wopanga Telzap 40 mg
Mankhwalawa amapangidwa ku Turkey ndi kampani yopanga mankhwala "Zentiva Saglik Urunlegi Sanai ve Tijaret".
Ndemanga za Telzap 40 mg
Madokotala
Ekaterina, wamtima wazaka, wodziwa ntchito zamankhwala - zaka 11
Telzap yadzikhazikitsa ngati mankhwala othandiza komanso osavuta kugwiritsa ntchito. Imakhala ndi zochita zazitali, zovuta zochepa ndipo imakhala yotsika mtengo.
Vladislav, cardiologist, wodziwa ntchito zamankhwala - zaka 16
Mapiritsiwa amathandizira kuthetsa zizindikiro za matenda amtima komanso amachepetsa chiopsezo cha stroko komanso mtima. Gawo lofunika lamapiritsi ndi kuchuluka kochepa kwa contraindication. Chithandizocho chimavomerezedwa bwino ndi odwala okalamba komanso anthu omwe ali ndi matenda amtundu wa 2.
Odwala
Polina, wazaka 52, Ufa
Ndili ndi matenda a mtima. Popewa zovuta, dokotala adalemba Telzap. Ndimatsatira bwino malingaliro a katswiri wamtima. Ndikumva bwino, palibe mavuto.
Valery, wazaka 44, Asbest
Ndine wodwala matenda ashuga (mtundu 2 shuga). Pakati pa miyala yoikika, pali Telzap. Dokotala anachenjeza kuti mulingo uyenera kuyang'aniridwa mosamala. Kuphatikiza apo, ndimakonda kudziwa kuchuluka kwa glycemia. Ndine wokhutira ndi zotsatira zake mpaka pano.
