Pofuna kukhazikika ku boma pakukakamizidwa kwambiri, Amlodipine ndi Lorista amatengedwa nthawi yomweyo. Mankhwalawa amatha kuyenderana kwambiri. Kuphatikiza mankhwala kumapereka mwayi wochepetsera kupanikizika. Ntchito ya minofu ya mtima imayenda bwino, chiopsezo chokhala ndi mtima wamtima chimachepa. Malinga ndi akatswiri a mtima ndi odwala, mankhwalawo amasintha thanzi tsiku loyamba, ngati mumwa mankhwalawa malinga ndi malangizo.
Mawonekedwe a Amlodipine
Mankhwalawa amakhala ndi amlodipine besilate mu 6.9 mg kapena 13.8 mg (5 mg kapena 10 mg ya amlodipine). Amlodipine amachepetsa kupanikizika kukhala kwabwinobwino poletsa njira za calcium. Zimalepheretsa kulowa kwa calcium m'maselo, ndikulimbikitsa kukula kwa mitsempha yamagazi. Mankhwala amasintha magazi kupita ku myocardium ndi angina pectoris. Pambuyo makonzedwe, minofu ya mtima sikusowa okosijeni ndipo zotumphukira zonse za mtima zimachepetsedwa.
Pofuna kukhazikika ku boma pakukakamizidwa kwambiri, Amlodipine ndi Lorista amatengedwa nthawi yomweyo.
Mankhwalawa amachepetsa kupanikizika mkati mwa maola 6-10 ndipo amalepheretsa kuphatikizira kwa kupatsidwa zinthu zosiyanasiyana. Zotsatira zimatha mpaka maola 24. Zotsatira zake zimatengera mlingo womwe umatenge. Kulandila sikukweza kugunda kwa mtima. Chidacho chitha kutengedwa ndi matenda a shuga, mphumu kapena gout. Pambuyo pakukonzekera pakamwa, ziwalo zomwe zimagwira ntchito zimatengedwa bwino ndikugawidwa mu minofu ya thupi. Kuchotsa theka-moyo ndi 2 masiku. Amathiridwa impso kudzera m'matumbo. Odwala omwe ali ndi vuto la chiwindi ndi ntchito yayitali, amadziunjikira m'thupi.
Zikuyenda bwanji Lorista
Mankhwalawa ali ndi potaziyamu wa losartan mu 12,5 mg, 25 mg, 50 mg ndi 100 mg. Gawo logwira ntchito limayambitsa kutsekeka kwa angiotensin 2 receptors a sub1pety a AT1. Sizingalepheretse kusintha kwa eniotensin. Imalimbikitsa kutsika kwa uric acid, kumalepheretsa kutulutsidwa kwa aldosterone. Pambuyo makonzedwe, ntchito minofu ya mtima bwino, kuchuluka kwa norepinephrine m'magazi amachepa, ndipo kukanikizika kumachitika.
Zotsatira zimachitika mkati mwa maola 5-6. Chidacho sichikhudza kuchuluka kwa cholesterol ndi triglycerides, glucose. Amamwa mwachangu komanso kumangidwa ku albin. Excretion ya metabolites imachitika kudzera m'matumbo ndi impso masana. Ndi chiwindi ntchito, ndende ya yogwira zinthu m'magazi ukuwonjezeka.
Kuphatikizika kwa Amlodipine ndi Lorista
Kuphatikizana kwa mankhwalawa kumathandizira kuchepetsa kuthamanga kwa magazi komanso kusintha magwiridwe antchito a mtima. Pambuyo pakukonzekera, ziwiya zimachepa pamodzi, ngozi yakuwonjezeka mobwerezabwereza imachepa, ndipo magazi amayenda bwino. Kupanikizika kumachepera mkati mwa maola 6 ndipo zotsatira zake zimakhala mpaka maola 24.
Kuphatikiza mankhwala kumatha kuchepetsa mwayi wopezeka ndi mtima kapena mitsempha yamagazi.
Zizindikiro zogwiritsidwa ntchito munthawi yomweyo
Ndikulimbikitsidwa kutenga limodzi ndi ochepa matenda oopsa. Chithandizo chithandiza kuchepetsa kupanikizika komanso kukonza thanzi la wodwala.
Contraindication ku Amlodipine ndi Lorista
Tengani Amlodipine ndi Lorista nthawi yomweyo yochotsa matenda oopsa pazotsutsana monga:
- Hypersensitivity kwa mankhwala zigawo zikuluzikulu;
- mimba
- kuyamwitsa;
- ntchito kwa chiwindi kapena impso;
- aakulu njira yolepheretsa hypertrophic cardiomyopathy;
- kusakhazikika kwa hemodynamics pakapita nthawi ya infaration;
- kugwedeza
- yotupa kwambiri matenda mu urology;
- kugwiritsa ntchito mankhwala okhala ndi aliskiren;
- hypolactasia;
- lactase enzyme akusowa;
- kuphwanya kusweka kwa galactose ndi glucose;
- kutsokomola;
- Hyperkalemia
- mitsempha ya varicose.
Muubwana ndipo ngati pakufunika kutero, hemodialysis sikulimbikitsidwa kuti ayambe kulandira chithandizo. Odwala omwe ali ndi ischemia, kupindika lumen ya mitsempha, matenda amitsempha, kuchepa kwa magazi komanso kuchepa kwa magazi ayenera kuchezeredwa ndi katswiri asanatenge. Ngati muli ndi angioedema, chithandizo sayenera kuyamba.
Momwe mungatenge Amlodipine ndi Lorista
Mlingo wa tsiku lililonse wa matenda oopsa ndi 25 mg Lorista ndi 5 mg Amlodipine. Mapiritsi amasambitsidwa pansi ndi kuchuluka kwamadzi. Mlingo ukuwonjezeka mpaka 100 mg + 10 mg kapena 50 mg + 5 mg pakalibe mphamvu. Lorista imayenera kutengedwa mu kuchuluka kwa 12.5 mg kapena 25 mg ngati pali kuphwanya kwa chiwindi.
Zotsatira zoyipa
Nthawi zina, zotsatira zoyipa zimatha kuchitika pambuyo pa utsogoleri, monga:
- Chizungulire
- kufooka
- ochepa hypotension;
- kutsokomola
- dyspepsia
- kuthawa;
- nseru
- thupi lawo siligwirizana mu urticaria, zotupa pakhungu;
- chiwindi ntchito;
- kulephera kwaimpso;
- kuchuluka kwa urea, potaziyamu, kapena creatinine;
- kukoka kwamtima;
- kutupa kwa miyendo;
- Hyperemia ya nkhope;
- kupweteka kwa minofu
- kuwonda;
- kupweteka kwam'mimba
- Edema ya Quincke;
- dazi.
Pamaso pa thupi lawo siligwirizana, ndikofunikira kukana kumwa mankhwala. Zizindikiro zimazimiririka atasiya kulandira chithandizo.
Malingaliro a madotolo
Oksana Robertovna, katswiri wamtima
Mankhwalawa onse amatengedwa limodzi ndi matenda oopsa, kuphatikizapo motsutsana ndi matenda ena a mtima. Amlodipine amathandizanso kuphipha kwamitsempha yamagazi ndikuyenda bwino kwa magazi kupita mumtima. Lorista amalepheretsa kuwonjezeka kwa kupanikizika ndikuwongolera zochitika za mtima. Mankhwalawa antihypertensive mankhwala, tachycardia sizichitika. Mutha kukwaniritsa kuchepetsedwa kwa nkhawa mukanama ndikukhala pansi. Iyenera kutengedwa mogwirizana ndi malangizo kuti muchepetse mawonekedwe osafunikira. Mukakalamba, adokotala ayenera kusankha mlingo woyenera.
Ndemanga za Odwala
George, wazaka 39
Anamwa mapiritsi a kuthana ndi ochepa komanso aimpso. Kupanikizika kumatsikira pazowoneka bwino mkati mwa maola awiri atatha kumwa koyamba. Mankhwalawa amalekeredwa bwino. Patsiku loyamba, chizungulire chinandivutitsa, koma pambuyo pake zinthu zinamuyendera bwino. Pa mankhwala, muyenera kusiya kudya. Thanzi liyenera kukhala lokwanira.
