Insulin Lantus idapangidwa kuti igwiritsidwe ntchito mu shuga ngati m'malo mwa mahomoni ake omwe. Dzina lake lazamalonda ndi Lantus Solostar. M'malemba apadziko lonse lapansi, dzina la Glargin limagwiritsidwa ntchito (chinthu ichi ndiye chinthu chachikulu). Monga mankhwala ena okhala ndi insulin, imakhala ndi vuto la hypoglycemic ndipo imangogulitsidwa kokha ndi mankhwala.
Zomwe zimagwira Lantus ndizofanizira za insulin ya anthu. Amadziwika ndi kuwonekera nthawi yayitali. Zotsatira zoopsa kwambiri zogwiritsira ntchito ndikukula kwa hypoglycemia, chifukwa chake ndikofunikira kutsatira malangizo omwe adokotala adalandira. Mutha kusintha mankhwalawa pokhapokha mawonekedwe a shuga atapezeka. Muyenera kuganiziranso za contraindication komanso chiopsezo cha mavuto.
Kuphatikizika, mawonekedwe omasulidwa
Kuti mugwiritse ntchito moyenera, mankhwalawa amamasulidwa mwanjira yopanda mtundu. Chofunikira kwambiri pakuphatikizidwa kwake ndi insulin Glargin.
Kuphatikiza apo, yankho limaphatikizapo:
- madzi
- nthaka ya chloride;
- sodium hydroxide;
- glycerol;
- hydrochloric acid;
- metacresol.
Odwala atha kugwiritsa ntchito mitundu ya mankhwala monga:
- Dongosolo la OptiClick. Ili ndi ma cartridge 5.
- Syringe cholembera OptiSet. Chiwerengero chawo paphukusi ndi 5 ma PC.
- Lantus Solostar. Poterepa, makatoni amaikidwa mu cholembera. Pazonse, pali ma cholembera asanu ndi atatu mu phukusi.
Mankhwalawa amagwiritsidwa ntchito ngati jakisoni wa subcutaneous komanso pokhapokha akutsimikiziridwa ndi dokotala.
Dongosolo la OptiClick
Zotsatira za pharmacological
Insulin Glargin analengedwa pogwiritsa ntchito njira yomwe imagwiritsidwanso ntchito mu DNA. Izi ndi zofananira zamahomoni amunthu. Pamene insulin yamtunduwu imaperekedwa kwa wodwala, zimachitika kuti zosagwirizana ndi ndale, zomwe microprecipitate imapangidwa.
Pakufunika, gawo logwiritsira ntchito la mankhwalawa limamasulidwa pang'onopang'ono kuchokera kwa iwo ndipo limakhudza thupi. Chifukwa cha izi, nthawi yayitali ya kukopa kwa Lantus ndikuchita kosalala imakwaniritsidwa.
Mothandizidwa ndi Glargin, maselo am'magazi amatenga mwachangu ndikusinthira glucose kumasamba omwe amafunikira, chifukwa chake kuphatikizika kwake kumachepa. Izi zimakhudzanso chiwindi, zimachepetsa kuchuluka kwa shuga. Ntchito ina ya mankhwalawa ndikulimbikitsa kapangidwe kazomwe amapangira mapuloteni.
Kutsimikizika kwa yogwira zinthu za mankhwala kumachitika pang'onopang'ono, komwe kumatsimikizira kutalika kwake. Lantus amayamba kuchita ngati patatha ola limodzi jakisoni (ngakhale izi zimatengera mawonekedwe a thupi la wodwalayo).
Nthawi yowonetsera imatanthauzanso zochitika zosiyanasiyana, koma kwakukulu ndizitali kwambiri, chifukwa chomwe jakisoni imatha kupangidwira kamodzi patsiku. Pa avareji, chiwerengerochi ndi maola 24. Munthawi yonseyi, magazi a wodwalayo amakhala ndi insulini komanso zotumphukira zake, zomwe zimapangidwa nthawi ya cleavage.
Zizindikiro ndi contraindication
Mankhwalawa ayenera kugwiritsidwa ntchito pokhapokha ngati adalangizidwa ndi dokotala. Ngakhale atazindikira koyenera, zimakhala zovuta kwambiri kuti wodwalayo adziwe ngati angalandire chithandizo chamankhwala. Kuphatikiza apo, chifukwa cha zina za thupi la wodwalayo, Lantus itha kukhala yovulaza, ndikofunika kuyeserera koyambirira.
Chizindikiro chachikulu chogwiritsa ntchito insulin yothandizira ndi matenda a shuga. Nthawi zambiri amagwiritsidwa ntchito ngati monotherapy. Koma pali nthawi zina pamene mankhwala ena amaphatikizidwa kuwonjezera pa iwo.
Mwa zosokoneza nthawi zambiri zimatchulidwa:
- zaka wodwala zochepera 6 zaka;
- chidwi cha thupi pakupanga.
Nthawi zina pamakhala mikangano.
Izi zikuphatikiza:
- mimba
- kuyamwitsa
- matenda a chiwindi
- kuphwanya impso ntchito;
- ukalamba.
Izi ndi zina mwa malire. Ngati ndi kotheka, Lantus ikhoza kugwiritsidwa ntchito, koma ndikofunikira kuyendetsa kuchuluka kwa shuga, popeza magulu awa a odwala amakonda kwambiri hypoglycemia.
Malangizo ogwiritsira ntchito
Mlingo wa mankhwalawa amasankhidwa ndi dokotala yemwe amaganizira za thupi la wodwalayo. Nthawi yomweyo, muyenera kuonetsetsa kuti palibe zotsutsana. Wodwala amayenera kuyang'anitsitsa kusintha konse komwe kumachitika panthawi ya chithandizo.
Maonekedwe a zoyipa zomwe zimatchulidwa nthawi zambiri zimawonetsa kukhalapo kwa chidwi ndi insulin kapena pathologies osadziwika, mokhudzana ndi omwe odwala amapititsidwa ku mankhwala ena. Kuongolera glucose kumafunikanso kuti musapitirire kuchuluka kwa mankhwalawa mosafunikira.
Lantus amangogwiritsa ntchito jakisoni wokhotakhota. Nthawi zambiri, mankhwalawa amaperekedwa nthawi imodzi patsiku (ndikofunikira kuti izi zichitike nthawi imodzi). Malo oyenera kwambiri a jakisoni ndi ntchafu, dera lamapewa ndi khoma lamkati lakumbuyo.
Lamulo lofunika ndikusinthana kwa malo a jakisoni. Ndi jakisoni pafupipafupi m'malo omwewo, lipodystrophy imatha kuchitika. Mothandizidwa ndi mtsempha wa magazi osokoneza bongo amaletsedwa kotheratu - mwanjira imeneyi, insulin imachita kwambiri, kupangitsa hypoglycemia.
Pa chithandizo, Lantus imatha kuphatikizidwa ndi mankhwala ena, ngakhale nthawi zambiri imagwiritsidwa ntchito ngati chithandizo chachikulu.
Phunziro la kanema pogwiritsa ntchito cholembera:
Odwala apadera
Magulu ena a odwala amafunikira chisamaliro chapadera posankha mankhwala ochizira. Kwa iwo, muyenera kuwerengera mosamala mankhwalawo ndikuwonetsetsa momwe mankhwalawo alili.
Odwala awa akuphatikizapo:
- Achikulire. Ukalamba umabweretsa kusintha kwakukulu pakugwira ntchito kwa chiwalo chonse komanso ziwalo za munthu payekhapayekha. Mwa anthu azaka zopitilira 65, impso ndi chiwindi sizigwira ntchito komanso mwa achinyamata ambiri. Ndipo kuphwanya magwiridwe antchito awo kumayambitsa boma kwambiri. Chifukwa chake, kugwiritsa ntchito Lantus ndi odwalawa kumafunikira kusamalidwa kwa malamulo osamala. Amachepetsa mlingo wa mankhwalawa, amapenda magwiridwe antchito a impso ndi chiwindi, ndipo amayang'anira kuchuluka kwa shuga.
- Ana. Kwa ana ochepera zaka 6, mankhwalawa amawonedwa ngati oletsedwa. Panalibe milandu yovulaza kuchokera ku izo, koma poti sizigwiritsidwa ntchito kwa odwala matenda ashuga ochepa. Kafukufuku wambiri wazotsatira zake pagulu la odwala nawonso sanachitike.
- Amayi oyembekezera. Pankhaniyi, zovuta zimakhalapo pakusintha pafupipafupi kwa misinkhu ya shuga komwe kumalumikizidwa ndi nthawi. Ngati pakufunika chithandizo cha insulin, chimagwiritsidwa ntchito, koma magazi amayang'aniridwa nthawi zonse kuti ayang'anire shuga, ndikusintha gawo la mankhwalawa malinga ndi zotsatira zake.
- Amayi oyamwitsa. Kwa iwo, chida ichi sichololedwa. Sizinakhazikitsidwe pepala lofufuza ngati Glargin adalowa mkaka wa m'mawere. Koma ngati ilowera, ndiye, malinga ndi madokotala, sizikhala zowopsa kwa khanda chifukwa cha mapangidwe ake a protein. Njira zopewera kusamala ndi zotere zimaphatikizapo kusintha kwa mlingo ndi zakudya. Izi zimalepheretsa kukula kwa zizindikiro zoyipa.
Ndi zomwe zili pamwambapa za Lantus zomwe zimaganiziridwa, ndizotheka kupanga chithandizo ndi chithandizo chake kukhala chopindulitsa kwambiri komanso motetezeka.
Zoyang'ana?
Mukamagwiritsa ntchito mankhwalawa, muyenera kusamala pantchito yomwe imafuna chisamaliro komanso kulondola. Pankhani ya kukula kwa chikhalidwe cha hypoglycemic, wodwalayo angakhudzidwe ndi kuchuluka kwa momwe angachitire komanso kuthekera kwakuya kwambiri.
Chenjezo liyeneranso kuchitidwa kwa odwala matenda ashuga omwe ali ndi vuto la chiwindi ndi impso. Chiwindi chimapangidwa ndi mankhwala okhala ndi insulin - amachepetsa kuchuluka kwa shuga.
Ndi kulephera kwa chiwindi, shuga amapangika pang'onopang'ono popanda zovuta zapadera. Mothandizidwa ndi Lantus, kuperewera kwa shuga kungachitike, komwe ndi kowopsa kwa anthu. Chifukwa chake, ndikofunikira kwa odwala kuti achepetse kuchuluka kwa insulin, kuyang'ana kwambiri kuopsa kwa matendawa.
Impso zimagwira nawo gawo limodzi pazinthu zomwe zimagwiritsidwa ntchito popanga mankhwala ndi metabolic. Ngati awonongeka ndipo sagwira ntchito mokwanira, ndiye kuti zimakhala zovuta kwambiri kuti atulutse insulini yoyenera. Chifukwa chotsika kwambiri pazandale, chinthucho chimadzunjikira m'thupi, kuchepetsa kwambiri shuga, chomwe chimakhala chowopsa pakukula kwa boma la hypoglycemic.
Zotsatira zoyipa ndi bongo
Mwambiri, kuyankha moleza mtima kwa Lantus kumawoneka ngati kwabwinobwino. Zotsatira zoyipa zimawoneka mukanyalanyaza malangizo kapena popereka mankhwala popanda kufufuza koyenera.
Zochitika zomwe zimadziwika kwambiri zimatha kutchedwa:
- Hypoglycemia. Vutoli limadziwika kuti ndilofala kwambiri komanso loopsa, chifukwa nthawi zambiri, popanda thandizo la dokotala, wodwalayo amatha kufa. Kupezeka kwake kukufotokozedwa ndikuti insulin yochuluka kwambiri imalowa m'thupi la munthu, chifukwa cha zomwe mafuta am shuga amatsika kwambiri. Vutoli limadziwika ndi kufooka, kukomoka, kukokana, ndi palpitations. Ndi mawonekedwe ochepa a hypoglycemia, amatha kuthetsedwa pogwiritsa ntchito maswiti okoma kapena shuga. Koma ngati vuto lalikulu la hypoglycemic likupezeka, chithandizo choyenera chamankhwala ndi chofunikira ndikofunikira.
- Zowonongeka. Kupezeka kwawo kumadzetsa kusintha kwakukulu kuzowonetsa shuga. Nthawi zambiri, pakapita nthawi, zovuta izi zimachotsedwa ngati mumatha kusunga shuga m'milingo yoyenera. Koma nthawi zina mavuto ngati amenewa amachititsa kuti anthu azivutika kuona.
- Lipodystrophy. Mawuwa amatanthauza kusokonekera kwa insulin. Izi zimachitika pobayira mbali yomweyo. Kuti mupewe izi, tikulimbikitsidwa kusinthanso malo ena obayira.
- Ziwengo. Kupezeka kwake kumalumikizidwa ndi chidwi cha wodwalayo pakupanga mankhwala. Nthawi zambiri, kuyesererana kumachitika kuti izi zisachitike. Zizindikiro za chifuwa zingakhale zosiyanasiyana. Nthawi zambiri, ming'oma, kuyabwa, ndi redness khungu zimachitika. Zotsatira zoyipa zimaphatikizapo kugwedezeka kwa anaphylactic.
- Zokhudza kwanuko. Amapezeka m'malo omwe mankhwalawo amathandizira. Nthawi zambiri izi zimatupa khungu, kuyabwa, redness. Pamene thupi limasinthana ndi mankhwalawo, mphamvu ya zomwe zimachitika imafooka, kenako ndikudutsa. Ndi kusungidwa kwawo komanso momwe akupitilira, ndikofunikira kuti mankhwalawa ndi ena.
Ngati zizindikiro zilizonse zam'magazi zikuwoneka, wodwala matenda ashuga ayenera kupita kwa dokotala. Zotsatira zoyipa nthawi zina sizikhala zoopsa, koma nthawi zina maonekedwe ake amafunika kuwongolera mwachangu dongosolo la mankhwalawo ndi kusiya mankhwala.
Mankhwala osokoneza bongo a Lantus amatsogolera ku hypoglycemia, chifukwa insulin yambiri imakhala m'thupi la wodwalayo. Njira zowachotsera zimatengera momwe mkhalidwewo uliri.
Kuchita ndi mankhwala ena ndi analogi
Kupanga kwa mankhwalawa kumakhudzidwanso ndi zinthu monga matenda a concomitant. Ngati alipo, muyenera kuphatikiza Lantus ndi mankhwala ena. Pali magulu a mankhwala motsogozedwa ndi momwe zochita za insulin zimasinthira, kotero muyenera kusintha dongosolo ndi mlingo.
Magulu otsatirawa a mankhwala amatha kuyambitsa kuchuluka kwa hypoglycemic:
- ACE zoletsa;
- salicylates;
- antidepressantant;
- sulfonamides;
- mankhwala a hypoglycemic.
Ngati kuphatikiza koteroko sikungapeweke, ndikofunikira kuchepetsa gawo la insulini kuti wodwala asakhale ndi hypoglycemia.
Mankhwala monga: kuchepetsa mphamvu ya mankhwala a insulin:
- estrogens;
- mankhwala a mahomoni;
- okodzetsa;
- sympathomimetics;
- proteinase zoletsa.
Kuti Lantus apitirizebe kugwira bwino ntchito zake, kuphatikiza kotero ndikofunikira kuti muwonjezere mlingo wake. Komabe, izi zikuyenera kuchitika malinga ndi zotsatira za kuyezetsa magazi.
Palinso mankhwala osokoneza bongo omwe zotsatira za insulin m'thupi zimatha kuwonjezeka kapena kuchepa. Izi zikuphatikizapo Pentamidine, Clonidine, Reserpine. Mwanjira imeneyi ndi zinthu izi zomwe zimafuna kusamala mukamagwiritsa ntchito Lantus.
Ndemanga za Lantus Solostar nthawi zambiri zimakhala zabwino, koma ngakhale izi, nthawi zina zimakhala zofunika kuyang'ana zina.
Mwa mankhwala a analog mulinso:
- Khalid. Chidacho chikuyimiridwanso ndi yankho la jakisoni. Chofunikira kwambiri pakuphatikizidwa ndi insulin yaumunthu. Mukamagwiritsa ntchito, muyenera kutsatira malangizo, muzindikire zolakwika.
- Chichewa. Yogwira ntchito ya mankhwalawa ndi insulin Lizpro. Humalog yakonzedwa kuti ikwaniritse magwiridwe antchito. Hypoglycemic zotsatira zimakhala chibadwiramo.
- Protafan. Mankhwalawa ali ndi isofan insulin. Kugwiritsidwa ntchito kwake kumachitika ndi jekeseni wa subcutaneous. Momwe zimakhalira ndi zofanana ndi za Lantus.
Kanema wofanana ndi insulin Lantus ndi Levemir:
Kusamutsa odwala kukhala mankhwala atsopano kuyenera kuchitika malinga ndi malamulo, chifukwa chake thandizo la dokotala likufunika pano. Kuphatikiza apo, sizingatheke kusankha chida choyenera popanda chidziwitso choyenera, chifukwa chake simuyenera kuchita izi nokha.
Mutha kugula mankhwalawa Lantus Solostar muchipatala ndi mankhwala, mtengo wake umachokera ku 3500 mpaka 5000 rubles.