Kubwereza kwa mankhwala kuti muchepetse mafuta m'thupi

Cholesterol yayikulu imawononga thanzi. Kuti muchepetse, magulu a mankhwala omwe amatulutsa kagayidwe ka lipid amapangidwa.

Amayikidwa kutengera mtundu wamatendawa komanso momwe thupi limagwirira ntchito.

Magulu ndi magulu

Cholesterol owonjezera umasungidwa m'thupi ndikuyika pamakoma amitsempha yamagazi.

Nthawi zambiri izi zimayambitsa matenda a mtima, matenda a mtima ndi stroko. Mankhwala osiyanasiyana amagwiritsidwa ntchito kuti achepetse kuchuluka kwamafuta akachilengedwe.

Mndandandandawu umaphatikizapo:

1. Ma Statin ndi ma enzyme blockers omwe akukhudzidwa ndikupanga cholesterol.
2. Niacin - chepetsa LDL, muchepetse chiopsezo cha kuwundana kwa magazi.
3. Mankhwala omwe amachepetsa mayamwidwe - letsa kuyamwa kwa cholesterol m'matumbo, kumasulidwa kwake m'mwazi.
4. Fibroic acid ndi mankhwala ochepetsa magazi triglycerides.
5. Otsata a bile acids - chotsani bile yambiri mthupi.

Chithandizo chilichonse chimakhala ndi zake, zotsutsana ndi zotsatira zake ndipo zimakhazikitsidwa kutengera mbiri ya wodwalayo komanso magawo ake.

Ma Statin, malo awo ndi mawonekedwe a pulogalamuyi

Ma Statin ndi mankhwala omwe amachepetsa cholesterol. Kuchita kwawo kuli ndi cholinga cholepheretsa enzyme, yomwe imayambitsa kupangika ndi kukula kwa LDL (cholesterol yoyipa).

Ma Statin akuimilidwa ndi mibadwo 4, omalizirawo amaonedwa ngati othandiza kwambiri. Dokotala dzina lake ndi HMG-CoA reductase inhibitors.

Mu chiwindi, mumakhala kuchepa m'magulu a cholesterol, ndipo m'magazi, kuchepa kwake.

Gulu la mankhwalawa limasinthasintha magazi, limasintha machitidwe amitsempha yamagazi, limatseketsa thrombosis ndi malo ophatikizika ndi atherosrance. Mukamatenga ma statins, pamakhala kuchepa pang'ono kwa shuga. Chochita chachikulu ndikuletsa kupanga michere ya chiwindi.

Pogwiritsa ntchito ma statins mwadongosolo, cholesterol imachepetsedwa ndi 40%. Kugwiritsidwa ntchito kuti muchepetse stroko ndi mtima. Amagwiritsidwa ntchito ngati hypercholesterolemia, atherosulinosis, matenda a mtima. Statin imakhudza chiwindi.

Pochiza ndi mankhwala, biochemistry yamagazi imayendera.

Kanema kuchokera kwa Dr. Malysheva okhudza ma statins:

Mwa zina zowonetsera ndizodziwika:

• mutu, kugona;
• thupi siligwirizana;
• utachepa libido;
• minofu kukokana ndi kupweteka;
• kusamalira chidwi ndi kuiwalaiwala;
• matenda am'mimba;
• thrombocytopenia;
• kuphwanya chiwindi;
• myopathy.

Contraindication kuti agwiritse ntchito:

• kukanika kwa chiwindi;
• mimba
• kukanika kwa impso;
• zaka mpaka 18;
• kuyamwitsa;
• tsankho kwa zigawo zikuluzikulu za mankhwala.

Statin amayimilidwa ndi njira zotsatirazi: Zokor, Lipostat, Rovakor (m'badwo woyamba), Leskol (m'badwo wa 2), Atoris, Tulip, Lipobay (m'badwo wachitatu), Rosuvastin, Krestor, Akorta (mankhwala amibadwo yatsopano).

Fibroic acid

Zothandiza kuchokera ku michere ya fibroic - kalasi ya mankhwala omwe amapangidwira kukonza metabolidi ya lipid. Amakhala gawo lachiwiri lokhazikika komanso kutchuka pambuyo pa ma statins.

Mankhwala oyamba m'gululi anali onenepa. Masiku ano, mayiko ambiri sagwiritsa ntchito mankhwalawa chifukwa chokhala ndi poizoni komanso zotsatira zake zoyipa. Pambuyo pake, Bezafibrate ,yprofibrate ndi Fenofibrate adayamba kugwiritsidwa ntchito.

Njira yomaliza ndiyo yabwino koposa. Amathanso kuyendetsa magazi, kutsika uric acid. Izi ndizofunikira makamaka kwa odwala matenda ashuga ndi gout nthawi yomweyo.

Zotsatira zazikulu za ma acids ndikuti amasintha mawonekedwe a lipid metabolism. Yogwira pophika Ichepetsa LDL, kumawonjezera HDL, ndipo matenda a lipid metabolism.

Imalimbitsa makoma amitsempha yamagazi, imachulukitsa, imalepheretsa mapangidwe. Zimalepheretsa magazi kuundana. Mothandizidwa ndi fibrate, kapangidwe ka triglycerides amachepetsa, kugawanika ndi kulepheretsa kukula kwa LDL kwathandizira. Kumwa mankhwala kumachepetsa chiopsezo cha matenda a mtima. Gulu la mankhwala limakhala ndi zotsatira zabwino pamachitidwe a mtima.

Zizindikiro zogwiritsidwa ntchito ndi:

• matenda ashuga dyslipidemia;
• cholesterol yayikulu (kuphatikiza mankhwala);
• kuchuluka kwa triglycerides;
• lipid kusalinganika;
• gout
• kunenepa
• kagayidwe kachakudya matenda.

Chenjezo liyenera kutengedwa pophatikiza michere ndi mankhwala ena. Izi zimatha kuwonjezera zovuta pa impso ndi chiwindi.

Zina mwazotsatira zoyipa:

• matenda am'mimba;
• aimpso kuwonongeka;
• mutu
• thupi lawo siligwirizana;
• kuchuluka kwa hepatic indices;
• kuphwanya chiwindi;
• mavuto amanjenje.

Kuphwanya kwakukulu komwe kumagwiritsidwa ntchito mafupa:

• kukanika kwa chiwindi;
• mimba ndi mkaka wa m`mawere;
• kulephera kwaimpso;
• uchidakwa;
• matenda a chiwindi;
• kuwerengetsa cholecystitis;
• zaka mpaka 18;
• cholelithiasis.

Mankhwala mosamala kwambiri ayenera kugwiritsidwa ntchito ndi achikulire.

Otsatira a bile acid

Ndiokhazikika ofanana acid - gulu la mankhwala okhudzana ndi lipid-kuchepetsa mankhwala. Mankhwala othandizira kuti muchepetse cholesterol yambiri.

Chofunika kwambiri ndikumanga kwa asidi wa bile mwanjira ina ya chimbudzi, kuponderezana kwa mafuta a cholesterol. Zomwe zimagwirira ntchito zimamanga ma asidi ndikuzipatula.

Kubwezera mayamwidwe a bile ndi kupewa. Kuphatikizika kwa HDL kumaperekedwa, ndipo LDL imatengedwa m'magazi. Kuphatikiza apo, glycosylated hemoglobin ndi glucose amachepetsedwa mwa odwala matenda ashuga.

Mankhwala samayamwa mu kayendedwe kazinthu, amatsitsidwa m'matumbo. Pankhaniyi, kukulitsa zotsatira zoyipa kumachepetsedwa. Choipa chodziwika bwino chimawonedwa kuchokera m'mimba thirakiti - kudzimbidwa, kusefukira kwamadzi, kudzimbidwa komanso kutulutsa, kusintha kwa kulawa.

Pakukhathamiritsa kwakukulu, othandizira amachepetsa mayamwidwe a B6 ndi mavitamini osungunuka a mafuta D, A, K, E. Pali chiopsezo chotaya magazi munthawi yamankhwala ndimankhwala ochokera kumankhwala owonongeka a mucous, chifukwa magazi amayamba kuchepa.

Panthawi ya mankhwala a FFA, cholesterol yoyipa imapukusidwa mpaka 45%, zomwe zimapangitsa lipid zovuta kukhala 20%. Kugwiritsa ntchito nthawi yayitali kumachulukitsa cholesterol yopindulitsa. Hypocholesterolemic zotsatira zimatheka pafupifupi pakatha mwezi wokhazikitsa. Mu maphunziro, zotsatira zabwino za FFA mu matenda amtima komanso zovuta zawo zidatsimikizika.

Mayina a mankhwala: Colestipol, Cholestyramine.

Zisonyezero zogwiritsidwa ntchito:

• kugunda kwamtima;
• Matenda a mtima a Ischemic;
• dyslipidemia;
• atherosulinosis;
• hypercholesterolemia;
• zovuta m'matumbo.

Mochenjera, mapiritsi amatengedwa kuti alembe matumbo, cholelithiasis.

Contraindication FFA imaphatikizapo:

• phenylketonuria;
• Hypersensitivity zimachitikira;
• hypertriglyceridemia;
• biliary thirakiti yotchinga;
• zilonda zam'mimba;
• magazi akusokonezeka;
• kudzimbidwa;
• billiard chotchinga;
• Hyperlipoproteinemia yamitundu yachitatu ndi IV.

Mankhwala osokoneza bongo amakhudza kuyamwa. Kudya kwambiri ndi ola limodzi kapena maola 4 mutatha kudya. Choyamba kutumikiridwa yaying'ono Mlingo, ndiye kuti pang'onopang'ono mlingo umakulitsidwa. Dongosolo lotere limachepetsa kukula kwa zoyipa.

Omwe amachokera ku ma FA amakhudza kuperewera kwa mankhwala angapo. Izi zikuphatikiza ndi ma penicillin maantibayotiki, ma diuretics, adrenergic blockers. Pakukonzekera kwa nthawi yayitali, biochemistry yamagazi imaperekedwa kuti iwunikire zizindikiro.

Amatanthawuza zomwe zimalepheretsa mayamwidwe a cholesterol m'matumbo

Mankhwala omwe amachepetsa kuyamwa kwa cholesterol m'matumbo amachepetsa kuyamwa kuti achepetse kuyamwa kwake m'magazi.

Gulu lomwe lidaperekedwako limaphatikizapo Lipobon, Ezetrol, Tribusponin, Guarem. Samatengeka m'magazi, amaphatikizidwa bwino ndi mankhwala ena, mosiyana ndi FFA samakulitsa secretion ya bile acids.

Zotsatira zake, atatha masiku 14 kumwa mankhwalawa, kuyamwa kwa cholesterol kumachepetsedwa ndi 50%. Kugwiritsa ntchito nthawi yomweyo sikukhudza kukhudzana kwa mankhwala kwa omwe aperekedwa. Pakutenga mlingo wa cholesterol yafupika mpaka 20%.

Zisonyezero zogwiritsidwa ntchito:

• homozygous achibale hypercholesterolemia;
• chachikulu hypercholesterolemia;
• kufooka kwa statin monotherapy;
• homozygous sitosterolemia.

Amagwiritsidwa ntchito molumikizana ndi mankhwala othandizira, pakadalibe zotsatira, amaphatikizidwa ndi ma statins. Nthawi zambiri owongolera a lipid amagwiritsidwa ntchito Essentiale, Lipostabil.

Mwa contraindication ntchito:

• kulephera kwa chiwindi;
• tsankho kapena kuchepa kwa lactose;
• Hypersensitivity zimachitikira;
• zaka zosakwana 18;
• Kugwiritsa ntchito munthawi yomweyo ndi ma fiber.

Zina mwazotsatira zoyipa:

• kutulutsa;
• chisangalalo;
• kusokonezeka kwa chopondapo (kudzimbidwa ndi kutsegula m'mimba);
• chiwindi ntchito;
• kutopa
• mutu.

Nicotinic acid

Nicotinic acid ndi vitamini sungunuka wa madzi wofunikira pakugwira bwino ntchito kwa thupi. Zochizira: kutsitsa cholesterol ndi tizigawo ta lipid, vasodilation.

Zimalepheretsa kukula kwa matenda amtima, kumapangitsa kuti mtima wawo ukhale pansi komanso kuti ukhale wofatsa.

Ikamamwa, nicotinic acid imasinthidwa kukhala chinthu chomwa nicotinamide. Amakhala nawo mu kagayidwe kachakudya ka mavitamini, kapangidwe kake, kupuma kwa minofu.

Katunduyo amathandizira kusintha kwaposachedwa kwam'mimba, kusintha ma lipoproteins, kutsika LDL ndi triglycerides, ndikuwonjezera HDL. Zimapukusidwa mu chiwindi, zotsekemera ndi impso. Peak ndende ya thunthu amafikira pambuyo mphindi 45.

Mndandanda wa mankhwala: Enduracin, Niceritrol, Acipimox. Kukonzekera kwa Nicotinic acid ndi zotsika mtengo komanso zambiri kwa anthu ambiri.

Zisonyezero zogwiritsidwa ntchito:

• gawo loyambirira la hyperlipidemia;
• ngozi yamitsempha;
• kusowa kwa vitamini PP;
• kupsinjika kwanthawi yayitali;
• atherosulinosis;
• pakukonzanso pambuyo povutitsidwa ndi mtima ndi stroko;
• microagniopathy;
• atherosulinotic mtima;
• zilonda pa mucous nembanemba;
• angina pectoris;
• nkhope yamitsempha yam'maso
• spasms a ziwiya zamanja;
• matenda ashuga polyneuropathy;
• enterocolitis, colitis, gastritis.

Contraindication kuti agwiritse ntchito:

• Hypersensitivity ku chinthu;
• zilonda zam'mimba zam'mimba (kutulutsa);
• zaka zosakwana 2 zaka.

Mosamala, mankhwalawa amatengedwa ndi anthu omwe ali ndi vuto la chiwindi, glaucoma, gout.

Zotsatira zoyipa pokonzekera:

• mafuta kulowa chiwindi kumachitika pa kumwa mankhwala waukulu;
• hypotension;
• khungu lawo siligwirizana;
• kuchuluka katulutsidwe wa chapamimba madzi;
• kulolerana kwa shuga;
• mkwiyo wa chapamimba;
• kuphwanya chiwindi;
• Hyperemia pakhungu;
• chiwopsezo chotenga myopathy chikaphatikizidwa ndi ma statins.

Njira zowonjezera

Kuphatikiza pa kukonza mankhwala, palinso njira zina zothandiza komanso zabwino kwambiri zochepetsera cholesterol. Izi zimaphatikizapo moyo woyenera komanso zakudya zabwino. Amagwiritsidwa ntchito ndi kuwonjezeka pang'ono kwa cholesterol - mpaka 18% yazonse.

Njira zodzitetezera zofananira ndi izi:

• kupatula zakudya zovulaza zazakudya;
• zolimbitsa thupi, kupsinjika, zolimbitsa thupi;
• kumwa zakudya zotsitsa mafuta m'thupi.

Kuchepetsa LDL, zakudya zamafuta ambiri ndi mavitamini amawonjezeredwa muzakudya. Musachotse mafuta, nyama yokazinga ndi mafuta, zakudya zamzitini, mbale zokhala ndi mafuta ambiri oyipa. CHIKWANGWANI chimapezeka kwambiri mu buledi, tirigu, nyemba, masamba ndi zipatso.

Ndizoyenera kudya zakudya zomwe mwachilengedwe zimachepetsa cholesterol yoyipa. Awa ndi mapeyala, chimanga, mafuta a azitona ndi mpendadzuwa. Mafuta acids omwe amapezeka m'mafuta a nsomba amasinthidwa ndi lipid metabolism. Kugwiritsa ntchito mwadongosolo kwa zinthu izi kumatha kuchepetsa LDL ndi 10%. Kugwiritsa ntchito mavitamini a lipoic acid ndi B kumathandizanso kuonetsa.

Vidiyo pazakudya kuti muchepetse cholesterol:

Mankhwala otsitsa a cholesterol ali ndi zinthu zingapo. Amawonetsedwa mu zovuta ndi monotherapy, amawonetsa katundu wabwino akagwiritsidwa ntchito moyenera. Cholinga cha mankhwala aliwonse chimayenera kukhala chovomerezeka.