Zisonyezero zogwiritsira ntchito ndi malangizo ogwiritsira ntchito mankhwala Fomati

Matenda a shuga salinso matenda osowa. Chaka chilichonse chiwerengero cha anthu odwala matenda amtunduwu chikuchulukirachulukira.

Kuti glycemia ibwerere mwakale, odwala ena amayenera kumwa mankhwala ochepetsa shuga a moyo kapena mankhwala a insulin.

Mwa njira zosiyanasiyana zakukonzekera mankhwala, odwala ambiri amakonda mankhwala monga "Fomati".

Zambiri, kapangidwe ndi mawonekedwe ake amasulidwe

Fomu (onani chithunzi) ndi mankhwala a hypoglycemic. Mankhwala ndi gawo limodzi la gulu la Biguanide, chifukwa chake limagwiritsidwa ntchito pochiza matenda a shuga a mtundu wachiwiri.

Monga momwe amakonzera onse a gulu la Biguanide, "Formetin" ili ndi gawo lina - Metformin hydrochloride. Kuchuluka kwake kungakhale 0.5, 0,85 kapena 1 g.

Zothandiza:

• croscarmellose sodium;
• magnesium stearate yogwiritsidwa ntchito popanga mankhwala;
• sing'anga yam'mero ​​povidone (polyvinylpyrrolidone).

Mankhwalawa amapezeka m'mapiritsi, momwe zimatengera mlingo:

• mozungulira 0,5 g;
• biconvex chowulungika (0,85 ndi 1 g).

Mapiritsi amagulitsidwa pamakatoni, ndipo chilichonse chimatha kukhala 30, 60 kapena 100.

Pharmacology ndi pharmacokinetics

Mankhwala "Fomu" amakhudza thupi motere:

• Imachepetsa ntchito ya gluconeogeneis m'chiwindi;
• amachepetsa kuchuluka kwa shuga omwe amatengedwa ndi matumbo;
• amathandizanso kuphatikizika kwa kuphatikizika kwa shuga m'magazi;
• kumabweretsa kuwonjezeka kwa minofu kumverera kwa insulin;
• sizomwe zimatsogolera pakukula kwa hypoglycemia;
• otsika triglycerides ndi LDL;
• amatero kapena amachepetsa thupi;
• amathandizira kusungunuka magazi.

The pharmacological kanthu amadziwika ndi mawonekedwe a mayamwidwe, kugawa ndi kuchulukitsa kwa zigawo zikuluzikulu.

1. Zogulitsa. Gawo lomwe limagwiritsa ntchito mankhwalawa limatengedwa ndimakoma am'mimba thirakiti itatha kumwa mapiritsi. The bioavailability wa muyezo mulingo kuchokera 50% mpaka 60%. Pazitali kwambiri ya mankhwalawa imayikidwa maola 2,5 pambuyo pa kukhazikitsa.
2. Kugawa. Zomwe zimagwiritsa ntchito mankhwalawa sizimayambitsa kulumikizana ndi mapuloteni a plasma.
3. Kuswana. Excretion wa zigawo zikuluzikulu za mankhwala ikuchitika osasinthika. Zophatikizira zotulutsira mkodzo. Nthawi yofunika theka la moyo wa mankhwalawa ndi kuyambira 1.5 mpaka 4.5 maola.

Pomwe zigawo zikuluzikulu za mankhwalawo zimadzunjikana m'thupi, muyenera kudziwa zomwe zingachitike. Nthawi zambiri, chifukwa chimayambitsa matenda aimpso.

Zizindikiro ndi contraindication

Mankhwala ndikofunikira mu milandu yotsatirayi:

• ndi kunenepa kwambiri kapena kunenepa kwambiri, pamene kudya sikuthandiza;
• ndi mtundu wachiwiri wa matenda ashuga.

"Fomu" siyenera kugwiritsidwa ntchito kokha pakuchepetsa thupi, ngakhale kuti mankhwalawo amathandiziradi kuchepa kwake. Kumwa mapiritsi ndikothandiza palimodzi ndi mankhwala a insulin odwala omwe ali ndi kunenepa kwambiri, komwe kumayendetsedwa ndi kukana kwachiwiri kwa mahomoni.

Milandu mukamamwa mankhwalawa ndiwotsutsana:

• ketoacidosis;
• chikomokere kapena precoma chifukwa cha matenda ashuga;
• kusintha kwa impso ndi chiwindi;
• zinthu zomwe zimabweretsa kukula kwa lactic acidosis, kuphatikizira kulephera kwa mtima, kusintha kwamitsempha yamagazi, gawo lodana ndi kulowerera kwam'mnyewa wam'mimba, uchidakwa, kuperewera kwa madzi m'thupi;
• poyizoni woledzera;
• kwambiri matenda opatsirana;
• othandizira opaleshoni;
• kuvulala
• x-ray, yokhudzana ndi kuyambitsa othandizira mosiyanitsa (masiku awiri asanafike ndi pambuyo pake);
• kutsatira zakudya zomwe zimalola kupezeka kwa zakudya za tsiku ndi tsiku zopitilira 1000;
• yoyamwitsa, komanso isanayambike mimba;
• Hypersensitivity pamagawo a mankhwala.

Malangizo ogwiritsira ntchito

Kusankhidwa kwa Mlingo kuyenera kuchitidwa kokha ndi dokotala yemwe amaganizira mawonekedwe onse a wodwalayo komanso njira ya matenda ashuga. Malangizo amawonetsa mlingo woyambirira wogwiritsa ntchito. Ikhoza kukhala kuchokera 500 mpaka 1000 mg patsiku.

Kusintha kwa muyezo kwa mankhwalawa sikuyenera kuperekedwa pasanathe masiku 15 mutatha piritsi yoyamba. Kuphatikiza apo, iyenera kusankhidwa pokhapokha pakulamulira glycemic. Mlingo wa tsiku ndi tsiku sungakhale wapamwamba kuposa 3000 mg. Nthawi zambiri, kukonza mankhwalawa kumafuna kutenga 1500-2000 mg / tsiku. Okalamba odwala sayenera kudya zosaposa 1 g za mankhwala othandizira.

Mapiritsi ayenera aledzeretse pambuyo chakudya. Mlingo wofotokozedwa ndi dokotala tikulimbikitsidwa kuti mugawidwe mosiyanasiyana, ndipo amwe mankhwalawa kawiri pa tsiku. Izi zitha kupewa kupezeka kwa mavuto okhudza chimbudzi.

Kanema wochokera kwa Dr. Malysheva okhudza Metformin ndi mankhwala otengera izi:

Odwala apadera

Mankhwala tikulimbikitsidwa kuti musagwiritse ntchito kwa odwala onse.

Magulu otsatirawa a odwala amaphatikizidwa ndi gulu lapadera:

1. Amayi oyembekezera komanso oyembekezera. Mayeso awonetsa kuti zigawo za mankhwalawa zimatha kukhala ndi vuto kwa ana onse m'mimba komanso pambuyo pobadwa.
2. Odwala omwe ali ndi matenda a chiwindi. Amaphatikizidwa mu mankhwala osokoneza bongo.
3. Odwala ndi mkhutu aimpso ntchito. Ndi kusintha kwakukuru kwa pathological, kugwiritsa ntchito mankhwala othandizira ndizoletsedwa. Nthawi zina, kuthandizika ndi mankhwalawa ndikotheka, koma kuyang'aniridwa kwamachitidwe a ziwalo.
4. Odwala okalamba. Pali chiopsezo cha lactic acidosis mwa anthu opitilira 60 omwe amangokhalira kugwira ntchito zolimbitsa thupi.

Malangizo apadera

Chithandizo cha mankhwalawa chili ndi zina:

1. Odwala ayenera kuyang'anitsitsa ntchito ya impso. Pafupipafupi kuwunika kotere kumachitika kawiri pachaka. Izi ndichifukwa choti zigawo za "Formethine" zimatha kudzikundikira mkati mwa thupi chifukwa chophwanya magwiridwe antchito a chiwalo ichi.
2. Ngati myalgia ikachitika, ndikulimbikitsidwa kuti muwone kuchuluka kwa plasma lactate.
3. Kugwiritsa ntchito "Fomu" pophatikiza ndi mpweya wa sulfonylurea kumafuna kuwongolera glycemic.
4. Chiwopsezo cha hypoglycemia chimawonjezeka pamene mapiritsiwa agwiritsidwa ntchito ndi mankhwala ena omwe amatha kuchepetsa shuga. Vutoli limakhala loopsa kwambiri poyendetsa kapena kuchita nawo chilichonse chokhudzana ndi kuthamanga kwa mayankho.
5. Pofuna kupewa lactic acidosis odwala omwe ali ndi vuto la metabolic, mankhwalawa ayenera kuyambitsidwa ndi kuchepetsa.

Zotsatira zoyipa ndi bongo

Umboni wa anthu odwala matenda ashuga akuwonetsa kuti chithandizo ndi wothandizila wa "Fayilo" mwina atha kukhala limodzi ndi zovuta zina:

1. Ponena za chimbudzi - nseru, kulawa kwazitsulo mkamwa, kusanza, kusowa kwa chakudya, kupweteka pamimba, chopondapo.
2. Lactic acidosis imawoneka. Vutoli limafunikira kuleka kwamankhwala chifukwa chakufa.
3. Hypovitaminosis imayamba.
4. Megaoblastic anemia imachitika.
5. Hypoglycemia imayamba.
6. Khungu limatuluka.

Ndi mankhwala osokoneza bongo ambiri, lactic acidosis imayamba. Zikatero, pamafunika kusiya mankhwala, ndipo wodwala ayenera kuchipatala. M'chipatala, anthu ambiri amakhala ndi lactate kuti atsimikizire kapena atsimikizire kuti matendowo ndi ozindikira. Kugwiritsa ntchito hemodialysis kumathandiza nthawi zambiri chifukwa cha kuphipha kwa lactate ndi metformin.

Kuyanjana Ndi Mankhwala Ndi Analogi

Mphamvu ya hypoglycemic imatheka ndi otsatirawa:

• jakisoni insulin;
• ACE zoletsa, MAO;
• Acarbose;
• Oxetetracycline;
• opanga beta
• zochokera sulfonylurea.

Kuchita bwino kumachepa ku izi:

• GCS;
• njira zakulera;
• adrenaline
• glucagon;
• mankhwala a mahomoni omwe amagwiritsidwa ntchito mu pathologies a chithokomiro;
• sympathomimetics;
• zotumphukira za phenothiazine, komanso nicotinic acid.

The mwayi wa lactic acidosis ukuwonjezeka kuchokera kumwa mankhwala "Cimetidine", Mowa.

Msika wogulitsa mankhwala umayimiriridwa ndi othandizira osiyanasiyana ochepetsa shuga. Zina mwazomwe zimatha kugwiritsidwa ntchito ngati m'malo mwa kukonzekera "Fomu", chifukwa cha kupezeka kwa metformin hydrochloride pakupanga kwawo.

Zofanizira:

• Vero-Metformin;
• Metformin Richter;
• Glucophage;
• Langerine;
• Glucophage Kutalika;
• Metfogamma.

Malingaliro odwala

Kuchokera pa ndemanga za anthu odwala matenda ashuga za mankhwala a Formetin, titha kunena kuti mankhwalawa sioyenera aliyense, chifukwa chake, asanagwiritse ntchito, kufunsa kwa dokotala ndikofunikira.

Ndinali ndi zaka makumi asanu ndi limodzi ndi zitatu nditapezeka shuga wambiri. Dokotala nthawi yomweyo adalimbikitsa kutenga Formetin. Zotsatira zake zidakondwera. Kupitilira zaka 2 za chithandizo, shuga amasungidwa mkati mwa 7.5 mmol / L. Ndizosangalatsa kwambiri kuti tinakwanitsa kuchotsa makilogalamu ena owonjezera 11, komanso kamwa yowuma siyinapezekenso.

Konstantin, wazaka 72

Kwa miyezi ingapo ndinayenera kusankha mankhwalawa kuti ndisinthe shuga. Matendawa adapezeka m'miyezi 5 yapitayo, koma chifukwa cha mapiritsi a formin ndizotheka kuyandikira shuga. Ndimawalandira ndi Siofor. Mosiyana ndi mankhwala ena omwe ndimalandira ndi mankhwalawa, ndilibe vuto ndi chimbudzi. Kwa aliyense yemwe sanatengepo mankhwalawa, ndikulimbikitsa kuyesera.

Elena, wazaka 44

Ndinawerenganso ndemanga zina ndipo ndimadabwitsidwa ndi kupambana kwa ena. Ine ndekha ndinamwa mankhwalawa kukakamira kwa adokotala. Asanamwe Metformin Teva, kunalibe mavuto. Ndipo ndikusintha kupita ku Formetin m'masiku atatu, ndidakumana ndi zovuta zonse zomwe zidalipo. Ndinali chizungulire, ndinali wamantha, ndimafooka kwambiri, ndipo sindinanene kanthu za enawo. Mankhwalawa sayenera kumwa pambuyo pa zaka 60, koma palibe amene adandiwuza. Fotokozani.

Arina, zaka 64

Mtengo wa mapiritsi 60 a formin umatengera mlingo. Ndipafupifupi ma ruble 200.