Kugwiritsirabe ntchito mankhwala omwe ali ndi insulin ndikofunikira kwa odwala mamiliyoni ambiri omwe ali ndi matenda ashuga.
Chifukwa chakuti kudya tsiku lililonse mankhwala ngati amenewo kumachitika ndi munthu wodwala matenda ashuga moyo wake wonse, zofunika zowonjezereka ziyenera kukhazikitsidwa pamlingo wa mankhwala.
Ndikofunikira kuti muchepetse zotsatira zoyipa za thupi, koma nthawi yomweyo ndikuwonetsetsa kuti chiwongola dzanja chanu chikhala bwino. Ndi chifukwa ichi kuti makampani opanga mankhwala amapanga ndikupanga zinthu zatsopano zomwe zimakhala ndi insulin. Makamaka, mankhwalawa ndi Tujeo - njira ina kwa Lantus kuchokera kwa wopanga yemweyo.
Kodi amagwiritsa ntchito chiyani?
Tujeo ndi Lantus amakonzekera insulin mwa mawonekedwe amadzimadzi a jakisoni.
Mankhwalawa amagwiritsidwa ntchito ngati mtundu 1 komanso matenda a shuga a 2, pomwe matenda a shuga sangatheke popanda kugwiritsa ntchito jakisoni wa insulin.
Ngati mapiritsi a insulin, kudya kwapadera komanso kutsatira mosamalitsa njira zonse zomwe zimaperekedwa sikumathandiza kuti shuga azikhala pansi pazovomerezeka, kugwiritsa ntchito Lantus ndi Tujeo. Monga kafukufuku wazachipatala wawonetsa, mankhwalawa ndi njira yothandiza yowunikira kuchuluka kwa shuga m'magazi.
Pakafukufuku wopangidwa ndi wopanga mankhwalawo - kampani yaku Germany ya Sanofi - kafukufuku adawakhudza odzipereka okwana 3,500. Onsewa adadwala matenda osokoneza bongo a mitundu yonseyi .. Kwa miyezi isanu ndi umodzi yofufuza zamankhwala, magawo anayi a kuyesera adachitika.
Mu gawo loyamba ndi lachitatu, chidwi cha Tujeo paumoyo wa odwala matenda ashuga a 2 adaphunzira.
Gawo lachinayi lidadzipereka pantchito ya Tujeo pa odwala omwe ali ndi matenda ashuga a mtundu woyamba. Malinga ndi zotsatira za kafukufukuyu, kuwoneka bwino kwambiri kwa Tujeo.
Chifukwa chake, kwa odwala matenda a shuga a gulu lachiwiri, kutsika kwapakati pa glucose kunali -1.02, ndikupatuka kwa 0.1-0.2%. Ambiri mwa anthu obwera chifukwa cha jakisoni anali owerengeka. Pachidziwitso chachiwiri, ndi 0% yokha mwa mituyi yomwe idakhala ndi zotsatira zosasangalatsa.
Zonsezi zinapangitsa kuti athe kupeza malingaliro okhudza chitetezo chamankhwala chatsopanocho ndikuyamba kupanga mafakitale. Tujeo tsopano likupezeka m'dziko lathu.
Lantus ndi Tujeo: zosiyana ndi zofanana
Kodi pali kusiyana kotani ndi Lantus, yemwe anali wodziwika ndi kufalitsidwa kale? Monga Lantus, mankhwalawa amapezeka mumachubu osavuta kugwiritsa ntchito.
Thumba lililonse limakhala ndi limodzi, ndipo kuti mugwiritse ntchito ndikwanira kutsegula ndikuchotsa kansalu ndikufinya dontho la zomwe zili ndi singano yomanga. Kugwiritsanso ntchito syringe chubu ndikotheka kokha asanachotsere injector.
Lantus SoloStar
Monga ku Lantus, ku Tujeo, chinthu chogwira ntchito ndi glargine - chithunzi cha insulin chopangidwa m'thupi la munthu. Glargine wophatikizika umapangidwa ndi njira yobwerezabwereza ya DNA yapadera la Escherichia coli.
Mphamvu ya hypoglycemic imadziwika ndi kufanana komanso nthawi yayitali, yomwe imatheka chifukwa chotsatira njira ya thupi la munthu. Chithandizo chogwira ntchito cha mankhwalawa chimayambitsidwa ndi minofu yamafuta a anthu, pansi pa khungu.
Chifukwa cha izi, jakisoni amakhala wosapweteka komanso wosavuta kuchita.
Acidic solution ndi yotenga mbali, zomwe zimapangitsa kuti pakapangidwe michere yaying'ono yomwe imatha kumasula pang'onopang'ono ntchito.
Zotsatira zake, ndende ya insulin imakwera bwino, yopanda nsonga ndi madontho akuthwa, komanso kwanthawi yayitali. Kukhazikika kwa chochitika kumawonedwa pambuyo pa ola limodzi pambuyo pa jekeseni wa mafuta ochulukirapo. Kuchitikaku kumatha maola osachepera 24 kuyambira nthawi yoyang'anira.
Nthawi zina, Tujeo imakhala yowonjezereka mpaka maola 29 - 30. Nthawi yomweyo, kutsika kwamphamvu kwa glucose kumachitika pambuyo pa jakisoni a 3-4, ndiye kuti, palibe kale kuposa masiku atatu atayamba kumwa mankhwalawa.
Tujo SoloStar
Monga Lantus, gawo la insulin limasweka ngakhale isanalowe m'magazi, m'matumbo amafuta, motsogozedwa ndi ma asidi omwe amapezeka m'menemo. Zotsatira zake, pakuwunikira, deta imatha kupezeka pazowonjezera zomwe zimapangitsa insulini kusweka ndimagazi.
Kusiyana kwakukulu kuchokera ku Lantus ndi kuchuluka kwa insulin yopanga muyezo umodzi wa Tujeo. Mukukonzekera kwatsopano, kumakhala katatu mwinanso 300 IU / ml. Chifukwa cha izi, kuchepa kwakukulu kwa kuchuluka kwa jakisoni tsiku ndi tsiku kumatheka.
Kuphatikiza apo, malinga ndi Sanofi, kuchuluka kwa mankhwalawa kunathandizira "kusalala" kwa mankhwalawa.
Chifukwa cha kuchuluka kwa nthawi pakati pa mabungwe, kuchepa kwakukulu kwa masheya a glargine kumatheka.
Ikagwiritsidwa ntchito moyenera, hypoglycemia imagwiritsidwa ntchito pokhapokha pokhapokha utasintha kuchoka ku mankhwala ena okhala ndi insulin kupita ku Tujeo. Pakadutsa masiku 7-10 mutangoyamba kumwa hypoglycemia imakhala chinthu chosowa kwambiri komanso cha atypical ndipo imatha kuwonetsa kusankha kosagwirizana pakanthawi kogwiritsa ntchito mankhwalawa.
Zowona, kuwonjezereka katatu kwa ndende kunapangitsa kuti mankhwalawo akhale osasinthasintha. Ngati Lantus angagwiritsidwe ntchito ngati matenda ashuga mwa ana ndi achinyamata, ndiye kuti kugwiritsa ntchito Tujeo ndizochepa. Wopanga amalimbikitsa kuti azigwiritsa ntchito mankhwalawa kuyambira azaka 18 zokha.
Mlingo
Wopangayo adapereka mwayi panjira yosinthira mankhwalawo. Solo-syringe imakupatsani mwayi kuti musinthe kuchuluka kwa mahomoni olowetsedwa mukuwonjezera gawo limodzi. Mlingo ndiwawokha, ndipo yoyenera imatha kusankhidwa mwanjira ina.
Kusintha kwa gawo mu cholembera cha Lantus
Choyamba muyenera kukhazikitsa mlingo womwewo womwe umagwiritsidwa ntchito ndi mankhwala am'mbuyomu. Kwa matenda a shuga a 2, nthawi zambiri amakhala magawo 10 mpaka 15. Pankhaniyi, ndikofunikira kuyesa glucose nthawi zonse ndi chipangizo chotsimikiziridwa.
Njira zosachepera zinayi ziyenera kuchitidwa patsiku, ziwiri za ola limodzi musanabaye jekeseni ndi ola limodzi mutatha. M'masiku atatu kapena asanu oyamba, kuchuluka pang'onopang'ono kwa mlingo wa mankhwalawa ndi 10-15% ndikotheka. M'tsogolomo, kuchuluka kwa mawonekedwe a Tujeo akayamba, mlingo umachepa.
Ndikwabwino kuti musachepetse kwambiri, koma kuichepetsa ndi 1 unit nthawi imodzi - izi zingachepetse chiopsezo cha kudumpha kwa glucose. Kuchita bwino kwambiri kumachitikiranso chifukwa chosowa kowonjezera.
Kuchita bwino kwambiri komanso chitetezo cha mankhwalawa zimatengera kugwiritsa ntchito moyenera. Choyamba, muyenera kusankha nthawi yoyenera ya jakisoni.
Mankhwalawa amayenera kuperekedwa kwa mphindi 30 asanagone.
Chifukwa chake, zotsatira ziwiri zimatheka. Komanso, kuchepa thupi thupi pogona kumathandizira kuchepetsa kuchepa kwamphamvu kwa shuga m'magazi.
Kumbali inayi, kuchuluka kwa nthawi yayitali kwa mankhwalawa kumathandizira kuthana ndi zomwe zimadziwika kuti "m'mawa kutacha", pomwe kuchuluka kwa glucose m'magazi kumawonjezeka kwambiri m'maola, m'mawa kwambiri.
Mukamagwiritsa ntchito Tujeo, muyenera kutsatira malangizo okhudza chakudya. Ziyenera kuchitika kuti chakudya chotsiriza chimalize maola asanu wodwala asanagone.
Chifukwa chake, ndikofunikira kwambiri kuti muzikhala ndi chakudya chamadzulo nthawi ya 18-00, osamadyanso chakudya usiku. Kafukufuku akuwonetsa kuti kusankha koyenera kwa regimen ya tsiku ndi nthawi ya jakisoni kumakuthandizani kuti mugwiritse jakisoni imodzi yokha ya mankhwala pa maola makumi atatu ndi zisanu ndi chimodzi.
Zabwino ndi ziti?
Malinga ndi odwala omwe asinthana ndi jakisoni wa Tujeo ndi mankhwala ena a insulin, ndi yosavuta kugwiritsa ntchito.
Mphamvu yofatsa yam'madzi, kusintha kwa thanzi, komanso kugwiritsa ntchito jakisoni mosavuta.
Poyerekeza ndi Lantus, Tujeo ali ndi kusiyana kocheperako, komanso kusapezeka kwazomwe zimachitika chifukwa chakuchepa kwambiri kwa glucose. Nthawi yomweyo, odwala ena adazindikira kuipiraipira atasintha mankhwala atsopano.
Pali zifukwa zingapo zoyipa:
- nthawi yolakwika ya jakisoni;
- kusankha Mlingo wolakwika;
- yoyenera mankhwala.
Ndi njira yoyenera yosankhira mlingo, zotsatira zoyipa za kugwiritsa ntchito Tujeo sizimachitika.
Nthawi yomweyo, nthawi zambiri chifukwa cha mlingo wosankhidwa bwino, shuga ya wodwalayo imachepetsedwa mosafunikira.
Makanema okhudzana nawo
Zambiri zomwe muyenera kudziwa za Lantus insulin mu kanema:
Chifukwa chake, chidacho chitha kuvomerezedwa kwa anthu omwe ali ndi matenda a shuga a 2, makamaka iwo omwe amafunikira phindu lochulukirapo kuchokera ku mahomoni omwe amaperekedwa. Malinga ndi kafukufuku, kuperewera kwa impso ndi kwa hepatic sikungapikisane pakugwiritsa ntchito mankhwalawa.
Palibe chovuta kugwiritsa ntchito mukakalamba. Nthawi yomweyo, kugwiritsa ntchito Tujeo paubwana sikulimbikitsidwa - pamenepa, Lantus ingakhale njira yabwino.
