Gluconorm - mankhwala a matenda a shuga a 2

Gluconorm ndi mankhwala otsika mtengo, ogwira ntchito, ophunziridwa bwino, koma osakhala otetezeka nthawi zonse. Amasankha mtundu wa 2 odwala matenda ashuga kuti achepetse magazi. Zinthu ziwiri zimapereka kuchepa kwa shuga - glibenclamide ndi metformin. Malinga ndi kafukufuku, kugwiritsa ntchito mankhwalawa kuphatikiza kumachepetsa hemoglobin wa 1% poyerekeza ndi kutenga imodzi mwa izo. Kwa odwala matenda ashuga ambiri, izi ndizotsatira zabwino kwambiri, zomwe zimapangitsa kuti pakhale malipiro a shuga mellitus, zomwe zikutanthauza kuti kupewa zovuta zomwe zimachedwa.

Kubwezera kwakukulu kwa Gluconorm ndi chiopsezo cha hypoglycemia, chifukwa amayesetsa kuti asapereke mankhwala kwa odwala omwe amathanso shuga.

Zizindikiro za gluconorm

Odwala ambiri omwe ali ndi matenda opha matenda a shuga, mankhwala amodzi sangathe kukhala ndi shuga wokwanira, kotero madokotala nthawi zambiri amapezeka kuti amaphatikiza pamodzi. Chizindikiro cha kupezeka kwake ndi glycated hemoglobin pamtunda wa 6.5-7%. Maganizo abwino kwambiri ophatikizidwa ndi metformin okhala ndi sulfonylurea derivatives (PSM), gliptins ndi incretin mimetics. Kuphatikizika konseku kumakhudza zonse insulin kukaniza ndi kuchuluka kwa kupanga insulini, ndipo chifukwa chake zimapereka zotsatira zabwino.

Kuphatikiza kwa metformin + sulfonylurea ndizofala kwambiri. Zinthu sizitha kuyanjana wina ndi mnzake, musachepetse kugwira ntchito bwino. Glibenclamide ndiyamphamvu kwambiri komanso wophunziridwa kuposa PSM yonse. Ili ndi mtengo wotsika kwambiri ndipo umagulitsidwa ku pharmacy iliyonse, chifukwa chake, kuphatikiza ndi metformin, glibenclamide imalembedwa nthawi zambiri kuposa mankhwala ena. Kuti mugwiritse ntchito mosavuta, mapiritsi a magawo awiri amapangidwa ndi zinthu ziwiri izi - Gluconorm ndi analogies.

Malinga ndi malangizo, Gluconorm imagwiritsidwa ntchito pokhapokha ngati matenda a shuga a 2, ngati kuwongolera zakudya, masewera, ndi metformin sikupereka kugwa kwa glucose kuti ikule bwino. Mlingo wa metformin suyenera kukhala wocheperako (2000 mg) kapena wololera odwala matenda ashuga. Komanso, gluconorm imatha kutengedwa ndi odwala omwe kale ankamwa glibenclamide ndi metformin payokha.

Matenda a shuga ndi kupsinjika kudzakhala chinthu chakale

• Matenda a shuga -95%
• Kuthetsa kwa mitsempha thrombosis - 70%
• Kuthetsa kwa kugunda kwamtima kwamphamvu -90%
• Kuthana ndi kuthamanga kwa magazi - 92%
• Kuwonjezeka kwa mphamvu masana, kukonza kugona usiku -97%

Kafukufuku wapezeka: mapiritsi ochepa omwe wodwala amatenga patsiku, amakonda kutsatira malangizo onse a dotolo, zomwe zikutanthauza kuti mankhwalawa amapezeka kwambiri. Ndiye kuti, kutenga Gluconorm m'malo mwa miyala iwiri ndi gawo laling'ono lopita kubwezeretsedwe kwabwino kwa matenda ashuga.

Kuphatikiza apo, kuwirikiza kawiri mu kuchuluka kwa mapiritsi ochepetsa shuga sikumapereka kuchepa komweko kwa shuga. Ndiye kuti, mankhwalawa awiri ocheperako amagwira ntchito moyenera ndikuwapatsa zotsatira zoyipa zochepa kuposa mankhwala amodzi mu muyeso wokwanira.

The zikuchokera ndi tanthauzo la mankhwala

Gluconorm imapangidwa ndi kampani ya ku Russia Pharmstandard mogwirizana ndi Indian Biopharm. Mankhwala amapezeka m'mitundu iwiri:

1. Mapiritsi a Gluconorm amapangidwa ku India, opakidwa ku Russia. Mankhwalawa ali ndi Mlingo wapamwamba wa 2.5-400, ndiye kuti, piritsi lililonse la metformin limakhala ndi 400 mg, glibenclamide 2.5 mg.
2. Mapiritsi a Gluconorm Plus amapangidwa ku Russia kuchokera ku mankhwala omwe agulidwa ku India ndi China. Amakhala ndi ma 2 Mlingo: 2,5-500 kwa odwala matenda ashuga omwe ali ndi insulin yambiri komanso 5-500 kwa odwala popanda kulemera kwambiri, koma ali ndi vuto la insulin lokwanira.

Chifukwa cha njira zingapo za muyezo, mutha kusankha mulingo woyenera wa wodwala aliyense yemwe ali ndi matenda a shuga a 2.

Tiyeni tiwone mwatsatanetsatane momwe zigawo za mankhwala Gluconorm zimagwirira ntchito. Metformin imachepetsa glycemia ya postprandial komanso kusala makamaka chifukwa kuchepa kwa insulin. Glucose imasiya zotengera mwachangu ngati chidwi cha minofu cha insulin chikuwonjezeka. Metformin imachepetsa kupangika kwa glucose m'thupi kuchokera pazinthu zopanda mafuta, imachepetsa kulowa kwake m'magazi kuchokera m'mimba.

Kwa odwala matenda ashuga, zina zowonjezera za metformin zomwe sizimagwirizanitsidwa ndi kuchepa kwa glycemia ndizofunikanso kwambiri. Mankhwalawa amalepheretsa kukula kwa angiopathy mwa kuphatikiza ndi lipids yamagazi, kumathandizira minofu yazakudya. Malinga ndi malipoti ena, metformin imatha kuletsa ma neoplasms. Malinga ndi odwala, amachepetsa kudya, amathandizira kuti azikhala wathanzi, amathandizira kuchepetsa thupi, komanso amathandizira kudya.

Glibenclamide ndi m'badwo wa PSM 2. Imagwira mwachindunji maselo a pancreatic beta: imatsitsa gawo lawo la chidwi chawo m'magazi a glucose, potero limakulitsa kupanga insulini. Glibenclamide imathandizanso glycogenogeneis, njira yosungirako shuga m'misempha ndi chiwindi. Mosiyana ndi metformin, mankhwalawa amatha kuyambitsa hypoglycemia, ovuta kwambiri kuposa oimira ena a gulu la PSM - glimepiride ndi glyclazide. Glibenclamide imawonedwa ngati yamphamvu kwambiri, komanso yoopsa kwambiri ya PSM. Sikulimbikitsidwa kwa odwala matenda ashuga omwe ali pachiwopsezo cha hypoglycemia.

Momwe mungatengere mankhwala a Gluconorm

Zotsatira zoyipa kwambiri za metformin ndi kugaya, glibenclamide - hypoglycemia. Mutha kuchepetsa kwambiri zovuta zotsatila za mankhwala ndi gluconorm, kumwa mapiritsi nthawi yomweyo ndi chakudya ndipo pang'onopang'ono kukulitsa mlingo, kuyambira ndi ochepera.

Mlingo wa mankhwala Gluconorm malinga ndi malangizo:

Ndi kukana kwamphamvu kwa insulin, komwe kumadziwika ndi anthu onenepa kwambiri omwe ali ndi matenda ashuga, metformin yowonjezera ikhoza kutumikiridwa. Nthawi zambiri pamenepa amamwa asanagone. Mulingo woyenera tsiku lililonse wa metformin amatengedwa kuti ndi 2000 mg, pazipita - 3000 mg. Kuchulukanso kwina kwa mankhwalawa ndi kowopsa ndi lactic acidosis.

Ndikusowa kwa chakudya chamagulu, Gluconorm imayambitsa hypoglycemia. Kuti mupewe, mapiritsiwa aledzera ndi zakudya zazikulu. Zogulitsa ziyenera kukhala ndi chakudya chamagulu, makamaka pang'onopang'ono. Simungalole kuyanjana kwakutali pakati pa chakudya, motero odwala amalimbikitsidwa kuti azidya zakudya zina zowonjezera. Ndemanga ya odwala matenda ashuga akuwonetsa kuti ngati munthu achita masewera olimbitsa thupi, shuga amatha kugwa pakapita mphindi. Pakadali pano, muyenera kuyang'anitsitsa thanzi lanu.

Zotsatira zoyipa ndi bongo

Zotsatira zoyipa zomwe wodwala matenda ashuga angakumane nazo akamagwiritsa ntchito Gluconorm kapena analogues:

• hypoglycemia chifukwa cha PSM;
• zimayambira kuchokera m'mimba, zimayambitsa metformin. Malinga ndi ndemanga, nthawi zambiri odwala matenda ashuga amakhala ndi matenda otsegula m'mimba komanso matenda m'mawa. Malangizo ogwiritsira ntchito amachenjeza kuti kupweteka kwam'mimba ndi kusanza ndizothekanso. Mavuto oterewa atabuka, musataye nthawi yomweyo ku Gluconorm, nthawi zambiri mu sabata thupi limasinthasintha ndikusiya kuyankha mankhwalawa;
• kuphwanya njira yopanga magazi. Kuchuluka kwa ma cell a m'magazi kumatha kutsika. Ngati chithandizo ndi Gluconorm sichitha, mapangidwe amwazi amabwezeretseka;
• lactic acidosis ndizovuta zosowa za shuga, zokhala mtundu 2. Popanda thandizo lakuchipatala, zimamupweteketsa mtima;
• tsankho kumamwa mowa pachimake;
• chapakati mantha angayankhe kugwiritsa ntchito gluconorm ndi mutu ndi kufooka;
• Thupi lawo siligwirizana n`zotheka, mpaka anaphylactic.

Zotsatira zoyipa monga hypoglycemia ndi lactic acidosis zimachitika chifukwa cha kuchuluka kwa Gluconorm. Itha kukhala:

1. Mwachindunji: odwala matenda ashuga amamwa kwambiri kuposa mlingo womwe wapatsidwa.
2. Zachindunji. Hypoglycemia imatha kuchitika pakakhala kusowa kwa chakudya m'thupi kapena glucose amawonongeka mwachangu panthawi yolimbitsa thupi komanso kupsinjika kwambiri, zonse zamaganizidwe ndi thupi. Kapangidwe ka lactate kumawonjezera mikhalidwe ya kuledzera, kufooka kwa ziwalo kumabweretsa hypoxia, kuvulala kwambiri komanso matenda opatsirana.

Contraindication

Pamene Gluconorm ya matenda ashuga singathe kugwiritsidwa ntchito:

• ndi chidwi chochulukirapo pazigawo za piritsi. Izi kuphwanya zikuphatikiza thupi lawo siligwirizana, ndipo ananena zinthu zosafunika zomwe zimafuna kuti discipinuation yake;
• ngati mtundu 1 wa matenda a shuga wapezeka;
• pa mankhwala a matenda owopsa a shuga, matenda oopsa ndi kuvulala. Lingaliro la kusintha kwakanthawi kwa mankhwala a insulin kumachitika ndi adokotala;
• ndi kuvulala kwambiri aimpso kapena kuwayika pachiwopsezo chotere;
• pa mimba ndi HB. Kuletsedwa kwa kugwiritsa ntchito Gluconorm ndikofunikira, chifukwa PSM pakupanga piritsi imatha kusokoneza kukula kwa mwana wosabadwayo, kumabweretsa hypoglycemia mwa mwana;
• mukumwa mankhwala othandizira. Kuphatikiza kwa Gluconorm ndi miconazole kapena fluconazole kumadzaza ndi hypoglycemia yayikulu. Mndandanda wa mankhwala omwe amakhudza zochita za Gluconorm akuwonetsedwa mu malangizo ogwiritsira ntchito;
• ngati wodwalayo adakumana ndi kale lactic acidosis kapena ali pachiwopsezo chotenga matendawa.

Analogs ndi choloweza

Ma analogues athunthu, komanso metformin ndi glibenclamide payokha, amatha kumwa moyenera muyezo womwewo wa Gluconorm. Ngati mukufuna kusintha chithandizo kuchokera ku mankhwala ena a sulfonylurea, Mlingo uyenera kusankhidwanso. Madokotala amalimbikitsa kusintha kuchokera ku Gluconorm kupita ku Amaryl kapena Glimecomb kupita kwa odwala matenda ashuga omwe ali ndi vuto la carbohydrate la 2, omwe nthawi zambiri amakhala ndi hypoglycemia.

Malinga ndi ndemanga, mphamvu ya Gluconorm ndi fanizo lake ili pafupi, koma anthu odwala matenda ashuga amakonda mtundu wa Glybomet wa ku Germany, poganiza kuti ndi mankhwala abwino kwambiri.

Malamulo osungira ndi mtengo

Gluconorm imagwira ntchito kwa zaka 3 kuyambira tsiku lopangidwa. Gluconorm Plus imaloledwa kusunga zosaposa zaka 2. Malangizowo alibe zofunikira pakusungira, ndikokwanira kuwona boma lotentha lopanda madigiri 25.

Anthu odwala matenda ashuga ku Russia amatha kulandira onse mankhwalawa malinga ndi mankhwala aulere omwe amalembedwa ndi katswiri kapena endocrinologist. Kugula pawokha kumawononga ndalama zotsika mtengo: mtengo wa mapiritsi 40 a Gluconorm ndi pafupifupi ma ruble 230, Gluconorm Plus imayambira 155 mpaka 215 rubles. mapiritsi 30. Poyerekeza, mtengo wa Glibomet yoyambirira uli pafupifupi ma ruble 320.

Ndemanga