Glformin yokhudza matenda ashuga - malangizo, ndemanga, mtengo

Kwazaka makumi angapo zapitazi, kukonzekera kwa metformin kwakhala gawo lofunikira kwambiri mu mtundu wa 2 matenda a shuga. Padziko lonse lapansi, mankhwala angapo omwe ali ndi metformin amapangidwa, imodzi mwazomwezo ndi Russia Gliformin yochokera ku kampani ya Akrikhin. Ndi analogue ya Glucophage, mankhwala oyambirira achi French.

Ndi matenda ashuga, mphamvu zawo m'thupi ndi zofanana, amachepetsa shuga wamagazi. Gliformin itha kugwiritsidwa ntchito palokha komanso monga gawo limodzi la chithandizo chokwanira mothandizana ndi othandizira ena odwala matenda ashuga. Chizindikiro cha kuperekedwa kwa mankhwalawa ndi insulin kukana, yomwe ilipo pafupifupi mitundu yonse ya 2 odwala matenda ashuga.

Momwe mapiritsi a Glyformin amagwirira ntchito

Mu zaka zochepa, dziko lapansi lidzakondwerera zaka zana za metformin. Posachedwa, chidwi cha chinthu ichi chikukula msanga. Chaka chilichonse amawululira zina zowonjezera.

Kafukufuku wazindikira zotsatirazi zabwino za mankhwala omwe ali ndi metformin:

1. Kuchepetsa shuga m'magazi mwa kukonza minyewa. Mapiritsi a Gliformin ndi othandiza makamaka kwa odwala onenepa.
2. Kuchepa kwa shuga kwa chiwindi, komwe kumakupatsani mphamvu yolimbitsa glycemia. Pafupifupi, shuga m'mawa amachepetsedwa ndi 25%, zotsatira zabwino zimakhala za anthu odwala matenda ashuga omwe ali ndi matenda apamwamba kwambiri a glycemia.
3. Kuchepetsa kuyamwa kwa glucose m'mimba, chifukwa choti kuphatikiza kwake m'magazi sikufika pazofunikira kwambiri.
4. Kukondoweza kwa mapangidwe a shuga m'malo a glycogen. Chifukwa cha depot ngati odwala matenda ashuga, chiopsezo cha hypoglycemia chimachepa.
5. Kuwongolera kwa lipid mawonekedwe amwazi: kuchepa kwa cholesterol ndi triglycerides.
6. Kupewa matenda a shuga pamitsempha yamagazi.
7. Zothandiza pamanenepa. Pamaso pa insulin kukana, Glformin itha kugwiritsidwa ntchito bwino pakuchepetsa thupi. Zimatheka chifukwa chochepetsa insulini m'magazi, zomwe zimalepheretsa kuchepa kwamafuta.
8. Glyformin ali ndi anorexigenic. Metformin, polumikizana ndi mucosa wam'mimba, imayambitsa kuchepa kwa chilimbikitso ndi kuchepa kwa kuchuluka kwa chakudya chomwe mumadya. Ndemanga yakuchepetsa thupi kumawonetsa kuti Glformin amathandizira kuti aliyense asaleme. Ndi metabolism yokhazikika, mapiritsi awa ndi osathandiza.
9. Imfa pakati pa odwala matenda ashuga omwe amamwa mankhwalawa ndi 36% kutsika kuposa odwala omwe amalandila chithandizo china.

Zotsatira pamwambapa zamankhwala zatsimikiziridwa kale ndipo zimawonekera mu malangizo ogwiritsira ntchito. Kuphatikiza apo, mphamvu ya antitumor ya Gliformin idapezeka. Ndi matenda a shuga, chiopsezo cha khansa ya m'matumbo, kapamba, bere ndi 20-50% kuposa. Mu gulu la odwala matenda ashuga omwe amathandizidwa ndi metformin, kuchuluka kwa khansa kunali kotsika poyerekeza ndi kwa odwala ena. Palinso umboni kuti mapiritsi a Gliformin amachedwetsa kuyambika kwakusintha kwam'badwo, koma izi sizinatsimikizidwe sayansi.

Matenda a shuga ndi kupsinjika kudzakhala chinthu chakale

• Matenda a shuga -95%
• Kuthetsa kwa mitsempha thrombosis - 70%
• Kuthetsa kwa kugunda kwamtima kwamphamvu -90%
• Kuthana ndi kuthamanga kwa magazi - 92%
• Kuwonjezeka kwa mphamvu masana, kukonza kugona usiku -97%

Zisonyezero zakudikirira

Malinga ndi malangizo, Gliformin akhoza kulembedwa:

• lembani odwala matenda ashuga a 2, kuphatikiza odwala azaka 10;
• ndi matenda amtundu wa 1, ngati pakufunika kuchepetsa insulin;
• odwala omwe ali ndi metabolic syndrome komanso zovuta zina za metabolic zomwe zingayambitse matenda a shuga;
• anthu onenepa ngati atsimikizira insulin kukana.

Malinga ndi malingaliro a mabungwe apadziko lonse a shuga ndi Unduna wa Zaumoyo ku Russia, za matenda amitundu iwiri a shuga, mapiritsi okhala ndi metformin, kuphatikiza Glformin, akuphatikizidwa pamzere woyamba wa chithandizo. Izi zikutanthauza kuti amalembedwa choyambirira, zikadzapezeka kuti kudya komanso kuchita masewera olimbitsa thupi sikokwanira kulipirira matenda ashuga. Monga gawo la mankhwala ophatikiza, Glformin imathandizira kuthandizira ndikuchotsetsa zovuta zomwe zimachitika chifukwa cha mankhwala ena.

Mlingo ndi mawonekedwe

Gliformin imapezeka m'mitundu iwiri. Mapiritsi a metformin achikhalidwe, 250, 500, 850 kapena 1000 mg. Mtengo wa phukusi la mapiritsi 60 umachokera ku ma ruble 130 mpaka 280. kutengera mlingo.

Fomu yosinthika ndikukonzekera kosinthika kwa Glyformin Prolong. Ili ndi Mlingo wa 750 kapena 1000 mg, wosiyana ndi Gliformin wanthawi zonse piritsi. Amapangidwa mwanjira yoti metformin imasiyira pang'onopang'ono komanso moyenera, kotero, kufunikira kwa mankhwala m'magazi kumakhalabe tsiku lonse mutatha kumwa. Kuchulukitsa kwa Glyformin kumachepetsa mavuto komanso kumapangitsa kuti munthu amwe mankhwalawo kamodzi patsiku. Piritsi imatha kuthyoledwa pakati kuti muchepetse mulingo, koma sangaphwanyidwe kukhala ufa, popeza katundu omwe amakhala nthawi yayitali adzatayika.

Malangizowa akutsimikiza kusintha kuchokera ku Glformin wokhazikika kupita ku Glformin Pronge kupita kwa odwala matenda ashuga omwe metformin imabweretsa zotsatira zoyipa. Simuyenera kusintha mlingo. Ngati wodwala atenga Glformin pa mlingo waukulu, sangasinthe kwa mankhwala owonjezera.

Malangizo ogwiritsira ntchito

Popewa zoyipa, gliformin kudya ndi kutsukidwa ndi madzi. Phwando loyamba ndimadzulo. Nthawi yomweyo monga chakudya chamadzulo, mutenge Glformin muyezo wocheperako komanso Glformin Prolong muyezo uliwonse. Ngati kudya kwa nthawi ziwiri kumayikidwa, mapiritsiwo amamwa mowa ndi chakudya cham'mawa.

Mlingo umakulitsidwa pang'onopang'ono mosasamala kanthu kuti wodwala amatenga mankhwala ena ochepetsa shuga:

• masabata awiri oyamba patsiku amamwa 500 mg, ndi kulolerana kwabwino - 750-850 mg. Pakadali pano, chiwopsezo cha zovuta zakudya zam'mimba ndizambiri. Malinga ndi ndemanga, zotsatira zoyipa nthawi zambiri zimakhala ndi mseru m'mawa ndipo zimayamba kuchepa pang'onopang'ono pamene thupi limagwirizana ndi Glformin;
• ngati munthawi imeneyi shuga sinafike bwinobwino, mlingo umachulukitsa mpaka 1000 mg, pakatha milungu iwiri - mpaka 1500 mg. Mlingo wotere umawonedwa ngati wabwino kwambiri, umapereka chiwopsezo chabwino kwambiri cha zotsatira zoyipa ndi kutsitsa shuga;
• Mlingowo umaloledwa kuti uwonjezeke mpaka 3000 mg (wa Glformin Prolong - mpaka 2250 mg), koma muyenera kukonzekera chifukwa chakuti kuchuluka kwa metformin sikungathandizenso kuchepetsa shuga.

Zotsatira zoyipa za mankhwalawa

Zotsatira zoyipa zomwe zimapezeka chifukwa cha mankhwalawa zimaphatikizanso kugaya chakudya. Kuphatikiza pa kusanza, mseru, ndi m'mimba, odwala amatha kumva kuwawa kapena zitsulo, kupweteka kwam'mimba pakamwa pawo. Kutsika kwakudyera ndikutheka, komabe, kwa mitundu yambiri ya 2 odwala matenda ashuga sangatchulidwe kuti ndi osafunika. Kumayambiriro kwa kugwiritsa ntchito mankhwalawa, zosasangalatsa zomveka zimawonekera mu 5-20% ya odwala. Kuti muchepetse, mapiritsi a Glformin amaledzera ndi chakudya, kuyambira mlingo wocheperako ndikuwonjezera pang'onopang'ono mpaka wabwino.

Kuphatikizika kwina kwa chithandizo ndi Glformin ndi lactic acidosis. Ichi ndi chikhalidwe chosowa kwambiri, ndipo malangizo ogwiritsira ntchito chiwopsezo akuyerekeza 0.01%. Choyambitsa chake ndi kuthekera kwa metformin kupititsa patsogolo kusweka kwa glucose pansi pamikhalidwe ya anaerobic. Kugwiritsa ntchito kwa Gliformin mu mlingo woyenera kungayambitse kuwonjezeka pang'ono chabe kwa lactic acid. Matenda ophatikizana ndi matenda amatha kubweretsa lactic acidosis: ketoacidosis chifukwa cha matenda a shuga oopsa, chiwindi, matenda a impso, minofu hypoxia, kuledzera.

Zovuta zina zomwe zimachitika chifukwa chogwiritsa ntchito mankhwalawa kwa nthawi yayitali zimaphatikizapo kuchepa kwa mavitamini B12 ndi B9. Nthawi zambiri, pamakhala zovuta zina zomwe zimachitikira kwa Glformin - urticaria ndi kuyabwa.

Contraindication

Kugwiritsa ntchito Gliformin ndizoletsedwa pamilandu yotsatirayi:

1. Ndi hypersensitivity zigawo za mankhwala.
2. Ngati wodwala matenda ashuga ali ndi chiwopsezo chachikulu cha minofu hypoxia chifukwa cha matenda a mtima, kuchepa magazi, kulephera kupuma.
3. Ndi kuwonongeka kwambiri kwa impso ndi chiwindi.
4. Ngati m'mbuyomu wodwalayo adakhala ndi lactic acidosis kamodzi.
5. Mwa amayi apakati.

Glyformin mu shuga amathetsa kwakanthawi maola 48 isanayambike ntchito ya radiopaque, mapulani omwe amagwiritsidwa ntchito, munthawi ya chithandizo cha kuvulala kwambiri, matenda ndi zovuta za matenda ashuga.

Analogs ndi choloweza

Ma Analogi achizolowezi a Gliformin

Kutalika kwa Glyformin

Malinga ndi odwala matenda ashuga, mankhwala odziwika bwino a metformin ndi French Glucofage ndi Siofor waku Germany. Ndi omwe omwe endocrinologists amayesa kupereka. Zomwe ndizofala kwambiri ndi Russian metformin. Mtengo wa mapiritsi am'nyumba ndi wotsika kuposa omwe amachokera kunja, kotero nthawi zambiri iwo amagulidwa ndi zigawo kuti agawire kwa odwala matenda ashuga.

Glformin kapena Metformin - zomwe zili bwino

Adaphunzira kupanga metformin mwapamwamba kwambiri ngakhale ku India ndi China, osatchulanso Russia ndi zofuna zake zapamwamba za mankhwala. Opanga manyumba ambiri amapanga mitundu yayitali yamakono. Kapangidwe kabwino kamapiritsi komwe kamangolembedwa ku Glucofage Long. Komabe, ndemanga zikunena kuti pochita palibe zosiyana ndi mankhwala ena owonjezera, kuphatikiza Glformin.

Mapiritsi okhala ndi metformin yogwira ntchito pansi pa dzina lomweli amapangidwa ndi Rafarma, Vertex, Gideon Richter, Atoll, Medisorb, Canonfarma, Izvarino Pharma, Promomed, Biosynthesis ndi ena ambiri. Palibe chilichonse mwa mankhwalawa chomwe chinganenedwe kukhala choyipa kwambiri kapena chabwino. Onsewa ali ndi mawonekedwe ofanana ndipo adakwanitsa kuperekera kuwongolera kwapamwamba.

Ndemanga Zahudwala