Hypothiazide ya mankhwala: malangizo ntchito

Kusokoneza kwamitsempha yam'mimba komanso mtima ndi vuto lomwe limachitika posachedwa kwa wodwalayo. Mankhwala Hypothiazide adapangidwa kuti aletse kukula kwa mawonekedwe ngati awa.

INN

Hydrochlorothiazide.

ATX

Khodi ya ATX ndi C03AA03.

Hypothiazide imathandizira kusokoneza kwamikodzo ndi mtima.

Kutulutsa mafomu ndi kapangidwe kake

Piritsi la piritsi limakhala ndi 25 kapena 100 mg ya hydrochlorothiazide, chinthu chomwe chimagwira. Zinthu zothandiza ndi:

• lactose monohydrate;
• wowuma chimanga;
• magnesium wakuba;
• talc;
• gelatin.

Zotsatira za pharmacological

Mankhwalawa ndi okodzetsa omwe amalepheretsa kubwezeretsanso kwa chlorine ndi ayoni a sodium. Nthawi yomweyo, kutulutsidwa kwa ma elekitiroma kumachuluka.

Kuphatikiza apo, mankhwalawa ali ndi vuto lothandiza kwambiri, koma samakhudzanso mphamvu zomwe ena amakhala nazo.

Kuchuluka kwake kumachitika maola 4 mutatha kumwa mankhwalawo.

Kuchuluka kwake kumachitika maola 4 mutatha Hypothiazide.

Pharmacokinetics

Chosakaniza chophatikizacho chimatengedwa mwachangu kuchokera mumimba. Kuchuluka kwa kuchuluka kwa hydrochlorothiazide mu plasma kumawonekera pambuyo maola 1.5-2.

Thupi limachotsedwa m'thupi ndi impso, pomwe silisintha. Kumangiriza kumapuloteni amwazi ndi 40%.

Zomwe zimathandiza

Mankhwalawa amalembedwera pamaso pa zomwe zikuwonetsedwa:

• kufunika koteteza mapangidwe amiyala mu kwamkodzo thirakiti;
• matenda oopsa;
• kuwongolera aimpso polyuria kumachitika nthawi ya shuga insipidus.

Hypothiazide ndi mankhwala kuti apewe mawonekedwe a miyala.

Kuphatikiza apo, chida chimagwiritsidwa ntchito ngati edematous syndrome, yomwe idayamba chifukwa cha izi:

• pachimake maphunziro a glomerulonephritis;
• premenstrual syndrome;
• kugwiritsa ntchito mankhwala a corticosteroid;
• nephrotic syndrome;
• aakulu aimpso kulephera;
• matenda oopsa a portal;
• kulephera kwa mtima kosatha.

Contraindication

Mikhalidwe yomwe kugwiritsa ntchito mankhwalawo ndizoletsedwa ndi:

• Hypercalcemia Refractory;
• anuria
• kukhudzidwa kwakukulu pazinthu zomwe zimachokera ku sulfonamides;
• kulephera kwambiri kwaimpso;
• Reflexory hyponatremia;
• kuphwanya kwa gren adrenal (matenda a Addison);
• kulephera kwambiri kwa aimpso, komwe phindu la creatinine limakhala locheperako 30 ml pa miniti;
• matenda ashuga, omwe ndi ovuta kuchiza.

Hypothiazide ya mankhwala ophatikizidwa mu anuria.

Hypothiazide amaletsedwa vuto la kusowa kwa adrenal gland.

Osatipatsa mankhwala a shuga.

Ndi chisamaliro

Pamaso pa zinthu zotsatirazi, mankhwalawa amagwiritsidwa ntchito mosamala:

• gout
• hypercalcemia;
• matenda a mtima;
• Hypersensitivity kuti lactose;
• coronary kapena ubongo sclerosis, yodziwika ndi koopsa maphunziro;
• hypokalemia;
• zotupa za chiwindi cha chikhalidwe cirrhotic.

Kugwiritsa ntchito mtima glycosides kumatanthauzanso zinthu izi.

Zambiri komanso zochuluka motani

Mankhwalawa amapangidwira pakamwa. Mankhwalawa amangoikidwa ndi dokotala, chifukwa choletsedwa kugwiritsa ntchito mankhwalawo pazokha.

Hypothiazide ya mankhwala yolembedwa ndi adokotala okha.

Atakula

Zotsatira zotsatirazi zamankhwala

1. Ndi matenda a shuga a insipidus, Mlingo ndi 50-150 mg.
2. Ndi PMS - 25 mg patsiku.
3. Pa edematous syndrome, chithandizo chimayambira ndi 25-100 mg, wothandizirayo amagwiritsidwa ntchito masiku awiri aliwonse kapena nthawi imodzi patsiku. M'mavuto akulu, kuchuluka kwa mankhwalawa kumawonjezereka mpaka 200 mg patsiku. Ngati ndi kotheka, sinthani mlingo wa 25-50 mg wa patsiku.
4. Pa chitukuko cha matenda oopsa - 25-50 mg patsiku. Mankhwala amatha kutumikiridwa mu mawonekedwe a monotherapy kapena munthawi yomweyo ndimankhwala ena.

Kwa ana

Kuchuluka kwa mankhwalawa amasankhidwa poganizira kulemera kwa wodwalayo. Nthawi zonse mankhwalawa ndi 37,5-100 mg. Zizindikiro izi zimagwira ntchito kwa ana a zaka 3-12. Odwala osakwana zaka 3 samalandira mankhwala.

Ana ochepera zaka 3 Hypothiazide sanalembedwe.

Musanadye kapena musanadye

Chidachi chitha kugwiritsidwa ntchito panthawi ya chakudya komanso mukatha kudya.

Kumwa mankhwala a shuga

Mankhwala amatchulidwa mosamala. Ndikofunikira kusintha mlingo wa mankhwala a hypoglycemic.

Pa mankhwala, wodwala ayenera kuyang'aniridwa ndi katswiri kuti azitha kugaya kagayidwe kazinthu.

Zotsatira zoyipa

Zochita zoyipa zimadziwika ndi kusalinganika kwa electrolyte ndi mawonekedwe ena okhudza machitidwe osiyanasiyana amthupi.

Kuchokera pamtima

Kulandila kwa mankhwala kumadziwika ndi zofananira:

• zotupa zam'mimba;
• postural hypotension;
• arrhythmia.

Zotsatira zoyipa za kutenga Hypothiazide zingakhale kutupa m'mitsempha.

Matumbo

Zotsatira zoyipa zimapangidwa:

• cholestatic jaundice;
• kudzimbidwa
• kuwonda;
• kutsegula m'mimba
• chiwindi ntchito;
• kutupa kwa kapamba;
• kuwonongeka kwa ndulu;
• yotupa yomwe ikukhudza tiziwalo tating'ono.

Hematopoietic ziwalo

Wodwala akuwonetsa zotsatirapo zake zoyipa:

• aplastic kapena hemolytic anemia;
• kuchepa kwa chiwerengero cha maselo oyera (nthawi zina);
• kuchuluka kwamitsempha m'magazi;
• agranulocytosis.

Chifukwa chotenga Hypothiazide, kuwerengeka kwa magazi a m'magazi kumatha kuchepa.

Pakati mantha dongosolo

Kuchokera kumbali yamanjenje, zizindikiro zimawoneka:

• mutu
• Chizungulire
• masomphenya osalala.

Kuchokera kwamikodzo

Amawonetsedwa kuti amapangidwa:

• kuwonongeka kwa minofu ya impso;
• kuphwanya mkodzo;
• osagwira bwino impso.

Kuchokera ku kupuma

Palibe umboni wa zoyipa zomwe zimakhudzana ndi kupuma kwamphamvu.

Pakhoza kukhala vuto lina mu impso mutagwiritsa ntchito Hypothiazide.

Matupi omaliza

Zizindikiro zikuwonekera:

• kudziwa dzuwa;
• necrotic vasculitis;
• kutentha thupi.

Woopsa milandu, wodwalayo amakula mapapu edema - kupuma mavuto syndrome.

Malangizo apadera

Kuyenderana ndi mowa

Kumwa mowa ndi hypothiazide kumatha kuyambitsa zotsatirapo zoyipa.

Zokhudza mphamvu pakuwongolera njira

Malangizowo akuwonetsa kuti mankhwalawa amatha kuthana ndi kuyendetsa galimoto chifukwa cha mawonekedwe ammbuyo.

Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere

Kugwiritsa ntchito kwanyengo yamkaka kumayendetsedwa ndi chiwopsezo chowopsa cha zinthu zoopsa mu bere, monga jaundice. Mu 1 trimester, mankhwala amatsutsana. Pa nthawi yoyembekezera mu II ndi III trimesters, imayikidwa mu milandu yapadera pamene phindu la mankhwalawo limakhala lalikulu kuposa kuvulaza komwe kwachitika.

Hypothiazide imathanso kuyendetsa.

Ngati yoyamwitsa siigwiritsidwa ntchito, chifukwa yogwira mankhwala imapita mkaka.

Bongo

Kugwiritsa ntchito mosayenera mankhwalawa kumayambitsa bongo. Wodwala ali ndi zizindikiro za:

• kuthamanga kwa magazi;
• kuphwanya mkodzo;
• kuchepa kapena kuchuluka kwa mkodzo;
• Chizungulire
• kuwonjezeka kwa ndende ya urea nayitrogeni m'magazi;
• ludzu
• kufooka
• tachycardia;
• minofu kukokana;
• dziko lodzidzimutsa.

Funafunani thandizo mwachangu. Kuti achepetse vutoli, amayamba kusanza, kenako m'mimba ndikutsukidwa ndikuyambitsa kaboni.

Kuchita ndi mankhwala ena

Zomwe zimachitika mogwirizana ndi mankhwala ena:

• opioid analgesics ndi barbiturates amathandizira orthostatic hypotensive kwenikweni;
• Cholestyramine amachepetsa mayamwidwe;
• Amantadine imawonjezera kawopsedwe;
• NSAIDs zimakhudza diuretic ndi hypotensive katundu wa mankhwala;
• Lisinopril amathandizira kuwoneka ngati antihypertensive zotsatira;
• corticosteroids amatsogolera kukuwonjezeka kwa kuchuluka kwa potaziyamu wina m'thupi;
• Amiodarone imawonjezera mwayi wa arrhythmias;
• Mchere wa lithiamu umachulukitsa kuwopsa kwa hypothiazide chifukwa kuchepa kwa chilolezo cha impso.

Ndi bongo wa Hypothiazide, kuchepa kwa kupanikizika ndikotheka.

Analogi

Mankhwala ofanana ndi awa:

• Hydrochlorothiazide;
• Furosemide;
• Indapamide;
• Inspra;
• Lasix;
• Diuver;
• Veroshpiron;
• Spironolactone;
• Torasemide.

Kupita kwina mankhwala

Muyenera kulandira mankhwala kuchokera kwa dokotala.

Mtengo wa Hypothiazide

Mtengo wamapiritsi ndi ma ruble 80-120.

Kusunga mankhwala Hypothiazide

Chochita chimasungidwa m'malo amdima ndi owuma.

Tsiku lotha ntchito

Ndizoyenera zaka 5 kuchokera tsiku lomasulidwa.

Kukhala wamkulu! Mankhwala ndi dzuwa. Furosemide. (07.14.2017)Mwachangu za mankhwala osokoneza bongo. IndapamideMankhwala a diuretic Lasix

Ndemanga za Hypothiazide

Mikhail, wazaka 43, Chita

Mayi anga anayamba kukhala ndi mavuto ndi miyendo yake: kutupa ndi kuwawa. Ndinayamba kutenga mankhwala azitsamba, koma m'kupita kwa nthawi ndinazindikira kuti sizinawakhudze. Ndidapita kuchipatala, lotchedwa Hypothiazide. Mankhwalawa ndiokwera mtengo, motero tinatha kugula mankhwala. Mankhwalawa ali m'mapiritsi omwe amamezedwa mosavuta. Mphamvu ya okodzetsa idayamba pomwepo, koma chifukwa cha mankhwalawo, edema sinachepe. Komabe, zinthu sizinakulire, chifukwa kunalibe zoyipa.

Alexandra, wazaka 35, Stavropol

Ma kapisozi a Hypothiazide adalembedwa kuti agogo, chifukwa anali ndi madzimadzi m'thupi. Tinagula mankhwalawo, phukusi - mapiritsi 20, amatenga 1 pc. Agogo aamuna ankakonda kuthamangira kuchimbudzi. Edema inayamba kuchepa, kunalibe zotsatirapo zoyipa. Dokotala adalangiza zakudya zowonjezera kapena kudya Asparkam, chifukwa pa mankhwala, potaziyamu amachotsedwa m'thupi.

Anna, wazaka 49, St. Petersburg

Kugwiritsa ntchito hypothiazide kwathandiza kuthana ndi kuthamanga kwa magazi. Komabe, kuchuluka kwa magnesium ndi potaziyamu m'thupi kunachepa, chifukwa chake akuti akuyenera kutenga ndalama kuti athetse kuphwanya uku. Kuperewera kwa zinthu kunapangidwira ndi zakudya, monga Sindikufuna kuyika mankhwala ena pachiswe.