Ngati cholesterol yokwezeka yapezeka poyesedwa magazi, dokotalayo ayenera kupereka mankhwala apadera oteteza mtima ndi matenda a mtima. Mankhwalawa ali m'gulu la ma statins.
Wodwala ayenera kudziwa kuti amwe mapiritsi nthawi zonse. Matenda, monga mankhwala ena aliwonse, ali ndi zovuta zina, ndipo adotolo ayenera kuuza wodwalayo za iwo.
Aliyense amene wakhudzidwa ndi vuto la cholesterol yayikulu akudzifunsa: kodi pali mankhwala ena kuti asiyanitse kuchuluka kwa polojekitiyi komanso ngati angamwe.
Mankhwala a cholesterol amagawidwa m'magulu awiri:
- Madera
- Fibates
Monga ma adjuvants, lipoic acid ndi ma omega-3 acids amathanso kutha.
Statin - cholesterol yotsitsa mankhwala
Ma Statin ndi mankhwala omwe amapangitsa kuti thupi lizitha kuchepa kupanga ma enzymes ofunikira pakupanga cholesterol m'magazi. Ngati muwerenga malangizo a mankhwalawa, ndiye kuti zotsatirazi zimayikidwa pamenepo:
- Statin amachepetsa cholesterol yamagazi chifukwa cha kuletsa kwa HMG-CoA kuchepetsa komanso kupondereza kaphatikizidwe m'chiwindi.
- Statins amathandizira kuchepetsa cholesterol yayikulu mwa anthu omwe ali ndi homozygous hypercholesterolemia, omwe sangathe kuthandizidwa ndimankhwala ena kuti achepetse cholesterol.
- Statin amachepetsa cholesterol yathunthu ndi 30-45%, ndi cholesterol yotchedwa "yoyipa" - mwa 45-60%.
- Kuchulukana kwa cholesterol yothandiza (kuchuluka kachulukidwe lipoproteins) ndi apolipoprotein A kumawonjezeka.
- Statin mwa 15% amachepetsa chiopsezo chokhala ndi ischemic pathologies, kuphatikizapo myocardial infarction, komanso mwayi wokhala ndi angina owonetsa myocardial ischemia ndi 25%.
- Sadzichiritsa komanso mutagenic.
Zotsatira zoyipa za ma statins
Mankhwala kuchokera pagululi ali ndi zovuta zingapo zoyipa. Zina mwa izo ndi:
- - Nthawi zambiri kumachitika mutu komanso kupweteka kwam'mimba, kusowa tulo, mseru, asthenic syndrome, kutsegula m'mimba kapena kudzimbidwa, kugona mosatekeseka, kupweteka minofu;
- - kuchokera ku manjenjenje pali paresthesia, chizungulire komanso malaise, hypesthesia, amnesia, zotumphukira neuropathy;
- - Kuchokera mmimba thirakiti - hepatitis, kutsekula m'mimba, anorexia, kusanza, kapamba, cholestatic jaundice;
- - Kuchokera kwamankhwala am'mimba - ululu wammbuyo ndi minyewa, kukokana, mafupa a mafupa, myopathy;
- - mawonetseredwe matupi awo - urticaria, zotupa pakhungu, kuyabwa, zotupa za pakhungu, matenda a Lyell, kuwopsa kwa anaphylactic;
- - thrombocytopenia;
- - zovuta za metabolic - hypoglycemia (kutsitsa glucose wamagazi) kapena shuga;
- - kunenepa kwambiri, kunenepa kwambiri, kusabala, edema yopuma.
Ndani ayenera kutenga ma statins
Kutsatsa kwa mankhwala kumati kuli kofunikira kuti muchepetse cholesterol, ndipo ma statins athandizira pamenepa, adzasintha moyo, kuchepetsa chiopsezo chokhala ndi stroko komanso mtima.
Kafukufuku wambiri awonetsa kuti mankhwala osokoneza bongo ndi njira yothandiza kwambiri yopewa ngozi za mtima komanso zimayambitsa zotsatira zoyipa zochepa. Koma muyenera kusamala ndi zonena ngati "aliyense amene amamwa ma statins ali ndi cholesterol yoyipa komanso cholesterol yabwino." Popanda kutsimikizira, mawu oterowo sayenera kudaliridwa.
M'malo mwake, pamatsutsanabe pakufunika kogwiritsa ntchito ma statins mukalamba. Pakadali pano, palibe malingaliro osatsutsana ndi gulu la mankhwalawa. Kafukufuku wina akutsimikizira kuti cholesterol ikakhala yayikulu kwambiri, kudya kwawo ndikofunikira kuti muchepetse chiopsezo cha matenda a mtima ndi mtima.
Asayansi ena amakhulupirira kuti mankhwalawa amatha kuvulaza thanzi la achikulire ndipo amayambitsa mavuto ambiri, ndipo phindu lawo motsutsana ndi maziko awa silabwino kwambiri.
Makhalidwe Osankhidwa a Statin
Munthu aliyense, kutengera malingaliro a dokotala, ayenera kusankha yekha ngati atenga ma statins. Ngati lingaliro labwino lipangidwe, ndiye kuti mapiritsi enieni a cholesterol ayenera kuikidwa ndi dokotala, poganizira matenda omwe akupatsirana.
Simungathe kumwa mankhwala kuti muchepetse cholesterol nokha. Ngati kusintha kulikonse kapena kusokonezeka kwa kagayidwe ka lipid kupezeka pang'onopang'ono, muyenera kulumikizana ndi cardiologist kapena akatswiri a zamankhwala. Katswiri yekha ndi amene angawunikire moyenera ngozi ya kutenga ma statin munthu aliyense, poganizira izi:
- zaka, jenda komanso kulemera;
- kukhalapo kwa zizolowezi zoipa;
- matenda oyamba a mtima ndi mitsempha yamagazi ndi ma pathologies osiyanasiyana, makamaka matenda a shuga.
Ngati statin adayikidwira, ndiye kuti muyenera kumwa mosamalitsa malinga ndi mankhwala omwe dokotala wakupatsani. Pankhaniyi, kuyezetsa magazi kwamomwemodzi kuyenera kumwedwa nthawi ndi nthawi. Potenga mtengo wokwera kwambiri wa mankhwalawa, ndikofunikira kukambirana momwe mungasinthidwe ndi wina wotsika mtengo.
Ngakhale ndibwino kumwa mankhwala oyambirirawo, popeza ma jeniki, makamaka omwe ndi ochokera ku Russia, ndi oyipa kwambiri kuposa mankhwala oyambitsidwa, kapenanso mankhwala ochokera kunja.
Fibates
Ili ndiye gulu lina la mapiritsi ochepetsa cholesterol yamagazi. Amachokera ku fibroic acid ndipo amatha kumangiriza bile bile, potero amachepetsa kaphatikizidwe ka cholesterol m'chiwindi. Fenofibates amachepetsa kuchuluka kwa cholesterol yambiri chifukwa amachepetsa kuchuluka konse kwa lipids m'thupi.
Kafukufuku wazachipatala awonetsa kuti kugwiritsa ntchito fenofibrate kumabweretsa kuti cholesterol yathunthu ikutsika ndi 25%, triglycerides ndi 40-50%, ndipo cholesterol yabwino imawonjezeka ndi 10-30%.
M'mayendedwe a fenofibrate ndi ciprofibrate amalembedwa kuti kugwiritsa ntchito kwawo kumabweretsa kutsika kwa zowonjezera zowonjezera (tendon xanthomas), kuchuluka kwa triglycerides ndi cholesterol kwa odwala omwe ali ndi hypercholesterolemia amachepetsa.
Tiyenera kukumbukira kuti mankhwalawa, monga ena ambiri, amayambitsa zovuta zingapo. Choyamba, izi zimakhudza kugaya chakudya, ndipo sikulimbikitsidwa kuti muwononge cholesterol panthawi yapakati.
Zotsatira zoyipa za fenofibrate:
- Matumbo dongosolo - kupweteka kwam'mimba, hepatitis, matenda a ndulu, kapamba, nseru, kusanza, kutsegula m'mimba, kugona.
- Musculoskeletal system - kupukusa myalgia, kufooka kwa minofu, rhabdomyolysis, minofu kukokana, myositis.
- Mtima wamtima - pulmonary embolism kapena venous thromboembolism.
- Mchitidwe wamsempha - kuphwanya kugonana, mutu.
- Mawonekedwe a mziwopsezo - zotupa pakhungu, kuyabwa, ming'oma, Hypersensitivity mpaka kuwala.
Kugwiritsa ntchito kwa ma statins ndi ma fiber nthawi zina kumapangidwira kuti muchepetse kuchuluka kwa ma statins, komanso. chifukwa chake, zovuta zawo.
Njira zina
Pa upangiri wa dokotala, mutha kugwiritsa ntchito mankhwala othandizira pakudya, mwachitsanzo, Tykveol, mafuta opendekeka, Omega 3, lipoic acid, omwe pamodzi ndi chithandizo chachikulu amathandizira kuchepa kwa cholesterol.
Omega 3
Akatswiri a mtima ku America amalimbikitsa mwamphamvu odwala onse omwe ali ndi cholesterol yayikulu yam'madzi kuti amwe mapiritsi amafuta a nsomba (Omega 3) kuti adziteteze ku matenda amtima komanso kupewa kukhumudwa ndi nyamakazi.
Koma mafuta a nsomba amayenera kumwedwa mosamala, chifukwa angapangitse kuti pakhale matenda a kapamba, ndipo mapiritsi a cholesterol pano sangathandize.
Tykveol
Ichi ndi mankhwala opangidwa kuchokera ku mafuta a nthanga. Amawerengera anthu omwe ali ndi atherosulinosis ya ziwiya zamafuta, cholecystitis, hepatitis.
Phytopreparation iyi imakhala ndi anti-yotupa, hepatoprotective, choleretic ndi antioxidant.
Lipoic acid
Amagwiritsidwa ntchito ngati othandizira komanso prophylactic wothandizila kwa coronary atherosulinosis, monga momwe zimakhalira ndi antioxidants amkati.
Imakhala ndi phindu pa kagayidwe kazakudya zam'magazi, imachulukitsa kupanga glycogen m'chiwindi, imasintha zakudya zamtundu wa neuroni, ndipo chopereka cha chiwindi chingatengedwe limodzi, kuwunika komwe kumakhala koyenera.
Vitamini
Zimathandizanso kukhala ndi cholesterol yokhazikika. Mavitamini B6 ndi B12, folic acid, vitamini B3 (nicotinic acid) ndiofunikira kwambiri.
Koma ndikofunikira kwambiri kuti mavitaminiwo ndi achilengedwe komanso osapangidwa, choncho zakudya zake ziyenera kukhala ndi zakudya zochuluka.
SissPren
Ichi ndichakudya chowonjezera chomwe chili ndi Fir phazi lochotsa. Muli ndi beta-sitosterol ndi ma polyprenols. Amagwiritsidwa ntchito pa matenda oopsa, atherosulinosis, cholesterol yamagazi ndi triglycerides.
Tiyenera kukumbukira kuti zakudya zowonjezera pakudya si mankhwala, chifukwa cha lingaliro lazachipatala, zimafooka kwambiri kuposa ma statins zimaletsa kufa msanga ndi ngozi zam'mimba.
Tsopano palinso mankhwala atsopano ochepetsa cholesterol yamagazi - ezetemib. Zochita zake zimatengera kuchepetsa kuyamwa kwa cholesterol kuchokera m'matumbo. Mlingo wa tsiku ndi tsiku wa mankhwalawa ndi 10 mg.
