Mapiritsi a Amoxicillin 250 mg ndi mankhwala ochulukitsa a beta-lactam. Komabe, mphamvu yawo yotsatsira imakhala yochepa, chifukwa mankhwalawa amawonongeka mchikakamizo cha penicillinase yopangidwa ndi tizilombo tina toyambitsa matenda.
Dzinalo Losayenerana
INN yamankhwala ndi Amoxicillin.
Mapiritsi a Amoxicillin 250 mg ndi mankhwala ochulukitsa a beta-lactam.
ATX
Mankhwala omwe akufunsidwa ali ndi code ya ATX J01CA04.
Kupanga
Gawo logwira la mapiritsi ndi mtundu wa amoxicillin wokwanira 250 mg. Mulinso:
- wowuma;
- talc;
- crospovidone;
- magnesium wakuba;
- calcium owawa.
Mapiritsi amagawidwa zidutswa 10. mu matuza kapena mitsuko ya pulasitiki ya ma 10 kapena 20 ma PC. Phukusi lakunja likuwoneka ngati kabokosi. Mmenemo, ikani 1 jar kapena 2 blister plates ndi pepala lokhala ndi malangizo.
Zotsatira za pharmacological
Mankhwala ndi mankhwala opangidwa ndi penicillin. Imawonetsa katundu wa bactericidal. Mphamvu yake ya antibacterial imatsimikiziridwa ndi kuponderezana kwa transpeptidase ntchito m'maselo a bakiteriya. Izi zimalepheretsa biosynthesis ya murein, yomwe imaphwanya kapangidwe ka khoma la cell ndikupangitsa kufa kwa tizilombo.
Mankhwala ndi mankhwala opangidwa ndi penicillin.
Kuchita kwa mankhwalawa kumafikira kwa anaerobic gram ambiri komanso ma gram-negative tizilombo toyambitsa matenda. Amoxicillin amathetsa bwino:
- Escherichia coli;
- Helicobacter pylori;
- Proteus mirabilis;
- matumbo ndi hemophilic coli;
- nsomba;
- strepto ndi staphylococci;
- causative wothandizirana ndi chibayo, anthrax, meningitis;
- zovuta zina za Klebsiella ndi Shigella.
Koma polimbana ndi mycoplasmas, rickettsia, tizilombo ta Proteus, β-lactamase komanso ma virus, sizothandiza.
Makhalidwe a mankhwalawa a mankhwalawa ndi ofanana ndi Ampicillin, koma bioavailability wamlomo wa Amoxicillin ndiwokwezeka.
Pharmacokinetics
Kuchokera mmimba, mankhwala opatsirana amatengedwa m'magazi. Amagwirizana ndi chilengedwe cham'mimba. Mlingo ndi kuchuluka kwa kuyamwa kwa chigawocho sikokwanira pakudya. Yake bioavailability ukufika 95%. Zolemba malire plasma kutsimikiza mtima pambuyo 1-2 mawola kumwa mankhwala. The achire ntchito ya mankhwala kumatenga pafupifupi maola 8. Mlingo wa kuchuluka kwa magazi ndi mankhwala kumadalira mwachindunji.
Amoxicillin amagawidwa mthupi. Mu achire kuchuluka, amalowa zosiyanasiyana zimakhala ndi zamadzimadzi, kuphatikiza:
- matumbo mucosa;
- mapapu;
- sputum;
- mafupa
- minofu ya adipose;
- chikhodzodzo;
- bile;
- chithokomiro cha Prostate ndi ziwalo za akazi;
- mkodzo
- pleural ndi peritoneal zamadzimadzi;
- zam'matumba.
Amadutsa placenta ndipo amapezeka mkaka wa m'mawere. Mlingo wolumikizidwa ndi mapuloteni amwazi umafika 20%. Popanda kutupa, salowa mu zotchinga magazi.
Gawo kagayidwe ka mankhwala kumachitika mu chiwindi.
Kagayidwe kachakudya limachitika m'chiwindi. Zinthu zowola sizikugwira ntchito. Mpaka 70% ya mankhwalawa amachotsedwa mu mawonekedwe ake apoyamba. Mutatenga piritsi limodzi la 250 mg, zomwe zimagwira mu mkodzo zimafika 300 μg / ml. Hafu ya moyo ndi maola 1-1,5. Polephera aimpso, chimbudzi chimalepheretsa. Gawo laling'ono la mankhwalawa limachoka m'thupi ndi ndowe.
Kodi mapiritsi a amoxicillin 250 amathandizira kuchokera
Mankhwalawa amapangidwira zochizira matenda oyambitsidwa ndi tizilombo toyambitsa matenda. Zisonyezo zogwiritsa ntchito maantibayotiki:
- Matenda a Otolaryngological - sinusitis, frontal sinusitis, pharyngitis, tonsillitis, tonsillitis, laryngitis, kutupa kwa khutu lapakati.
- Kugonjetsedwa kwa zida za bronchopulmonary - bronchitis, kuphatikiza, chibayo.
- Matenda a urogenital - pyelitis, cystitis, pyelonephritis, urethritis, prostatitis, cervicitis, endometritis, salpingitis, gonorrhea.
- Typhoid, paratyphoid, peritonitis, cholangitis, gastroenteritis, colitis, cholecystitis.
- Bacteria wam'mimba, kamwazi.
- Meningitis
- Borreliosis
- Kugonjetsedwa kwa listeria ndi leptospira.
- Septicemia.
- Erysipelas, impetigo ndi matenda ena amkhungu ndi zigawo za subcutaneous, kuphatikiza matenda opatsirana a mabala ndi kuwotcha.
- Kupewera kwa bakiteriya endocarditis ndi matenda a postoperative.
Ndi matenda ashuga
Matenda a shuga amayambitsa kukana kwa thupi, kotero matenda opatsirana mwa matenda ashuga amakula nthawi zambiri. Gwiritsani ntchito maantibayotiki m'malo mwa odwala. Nthawi zambiri, mankhwala omwe amafunsidwa amapatsidwa mavuto azakhungu, matenda a kupuma komanso kwamikodzo. Ndikofunika kuthandizira kuchipatala.
Contraindication
Mapiritsi sayenera kumwedwa ngati:
- tsankho kwa amoxicillin kapena othandiza mbali;
- mbiri ya ziwengo kwa mankhwala a beta-lactam;
- hay fever, mphumu;
- matenda mononucleosis;
- lymphocytic leukemia;
- colitis;
- zotupa za chiwindi.
Iwo saledzera nthawi yoyamwitsa ndipo sapatsidwa kwa ana osakwana zaka zitatu.
Muyenera kusamala makamaka popereka mankhwalawa kwa amayi apakati ndi odwala omwe ali ndi vuto la impso kapena amene akuyembekezerera magazi.
Muyenera kusamala makamaka popereka mankhwala kwa amayi apakati.
Momwe mungatenge mapiritsi a Amoxicillin 250
Chida ichi chimatengedwa monga momwe dokotala wakupangira. Mlingo ndi nthawi ya maphunzirowa zimatsimikiziridwa payekhapokha malinga ndi zaka za wodwalayo, kuchuluka kwa matenda, kuopsa kwa matendawa, mphamvu zake.
Asanadye kapena pambuyo chakudya
Mutha kumwa mapiritsi nthawi iliyonse. Kudya sikukhudza mayamwidwe a amoxicillin. Ndikulimbikitsidwa kugwiritsa ntchito mlingo wa tsiku ndi tsiku m'magawo atatu, ndikuwona kufanana pakati pa Mlingo. Mapiritsiwo amezedwa lonse, sayenera kutafuna.
Masiku angati kumwa
Nthawi yayitali ya mankhwala ndi masiku 5-12. Ngati ndi kotheka, njira yochizira imatha kukulitsidwa.
Zotsatira zoyipa za Amoxicillin 250 mapiritsi
Pa mankhwala opha maantibayotiki, zovuta zomwe zimachokera ku ziwalo zosiyanasiyana ndi machitidwe awo zimawonedwa.
Matumbo
Colitis yotheka, stomatitis, glossitis, kuphwanya kwamphamvu malingaliro, nseru, kusanza, kutsegula m'mimba, kupweteka kwa anus, dysbiosis, cholestatic jaundice.
Pakati mantha dongosolo
Chizungulire, kufooka, migraines, overexcitation, nkhawa yowonjezera, kusokonezeka kwa kugona, chisokonezo, kukokana kwa minofu, arthralgia kumawonedwa.
Amoxicillin angayambitse chizungulire.
Kuchokera ku kupuma
Nthawi zina zimakhala zovuta kupuma.
Kuchokera pamtima
Tachycardia imayamba. Nthawi zambiri pamakhala kuphwanya hematopoiesis.
Matupi omaliza
Nthawi zambiri, khungu limakumana ndi mawonekedwe: urticaria, hyperemia, thupi totupa, kuyabwa, edincke, edema, anaphylactic kugwedezeka, mawonekedwe a seramu. Milandu ya mawonekedwe a multiforme exudative erythema ndi poermal necrolysis woopsa idadziwika.
Malangizo apadera
Mukamamwa Amoxicillin, muyenera kuwunika momwe impso, chiwindi ndi hematopoiesis zimachitikira.
Ngati kholo la antibayotiki ndilofunikira, jakisoni wa Ampicillin amagwiritsidwa ntchito.
Pambuyo pakutha kwa zizindikiro zoyambirira, mapiritsiwo amatengedwa kwa masiku osachepera a 2.
Chifukwa chogwiritsa ntchito mankhwalawa, kupatsirana mphamvu kumatha. Ndi hypersensitivity kwa penicillins, kuyanjana kwamtanda ndi oimira gulu la cephalosporin ndikotheka.
Ngati matenda am'mimba akuchitika pakumwa, ndiye kuti sizingatheke kugwiritsa ntchito mankhwala omwe amatchinga matumbo kuti athane nawo.
Chifukwa chakuchepa kwa njira zolerera, njira zina zakulera zingafunikire.
Momwe mungaperekere ana
Mapiritsi amaloledwa kutenga kuchokera zaka zitatu. Mlingo wa 250 mg wopangidwa kwa odwala azaka 5-10. Ana aang'ono aang'ono amakulimbikitsidwa kuti apereke maantibayotiki mwa kuyimitsidwa kapena madzi. Kuyambira wazaka 10 wokhala ndi thupi loposa 40 makilogalamu, mulingo womwewo uyenera kugwiritsidwa ntchito ngati wodwala wamkulu.
Ana aang'ono aang'ono amakulimbikitsidwa kuti apereke maantibayotiki mwa kuyimitsidwa kapena madzi.
Kuphatikiza pa metronidazole, mankhwalawa omwe amagwiritsidwa ntchito sagwiritsidwa ntchito mpaka zaka 18.
Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere
Pa kubereka komanso poyamwitsa, kugwiritsa ntchito maantibayotiki kuyenera kukhala njira yomaliza. Kukhazikika koyambirira ndi dokotala komanso kusamutsa mwana kwakanthawi kuti akwanitse kudya ndi zinthu zofunika kuvomerezedwa ndi Amoxicillin.
Bongo
Kuchulukitsa mlingo waukulu kumawonetsedwa ndi kusanza ndi kutsekula m'mimba, komwe kumayambitsa kuperewera kwamadzi ndi kusakhazikika muyezo wa electrolyte. Ngati sipanadutse maola 1.5 kuchokera mukumwa mapiritsiwo, ndiye kuti muyenera kutulutsa m'mimba (kusambitsa kapena kusambitsa) ndi kutenga enterosorbent, mwachitsanzo, makala oyambitsa. Ngati ndi kotheka, zibwezereni madzi osungiramo magetsi. Palibe mankhwala ena apadera, chifukwa chake, pakakhala mankhwala ochulukirapo, amatha njira ya hemodialysis.
Ndi chithandizo chotenga nthawi yayitali, michere ya neurotoxic imatha kuchitika komanso kusintha kachulukidwe kapangidwe ka magazi kumatha kuchitika. Vutoli limasintha pakumalizira maphunziro.
Kuchita ndi mankhwala ena
Plasma wozungulira wa mankhwala amafunsidwa pamaso pa ascorbic acid amawonjezeka ndikuchepa mchikakamizo cha glucosamine, maantacid, aminoglycosides, ndi mankhwala ofewetsa tuvi tolimba. Allopurinol, Probenecid, NSAIDs, okodzetsa ndi ma tubular secretion blockers amachedwetsa kuchotsedwa kwake.
Amoxicillin imathandizira mphamvu ya anticoagulants osalunjika ndikuchepetsa mphamvu ya ethinyl estradiol, mankhwala a bacteriostatic, ndi njira zoletsa za estrogen. Kuopsa kwa methotrexate kumachulukana ndi kugwiritsidwa ntchito mosiyanasiyana ndi maantibayotiki.
Kuyenderana ndi mowa
Kumwa mowa kumapangidwa.
Zakumwa zoledzeretsa pamankhwala amaswa.
Analogi
Mankhwala omwe ali mu Mlingo wa 250 mg amapezeka osati pamapiritsi, komanso mawonekedwe a granules omwe amayenera kuyimitsidwa pakamwa, komanso makapisozi. Mankhwala ena amakhudzanso chimodzimodzi:
- Amoxil;
- Flemoxin Solutab;
- Ecobol;
- Amosin;
- Ospamox et al.
Kuti muwonjezere kuchuluka kwa maantibayotiki, ophatikiza othandizira ndi clavulanic acid, monga Amoxiclav, amapangidwa.
Kupita kwina mankhwala
Kupeza mankhwala ndi kochepa.
Kodi ndingagule popanda kulandira mankhwala?
Mankhwalawa amaperekedwa ndi mankhwala.
Mtengo wa mapiritsi
Mtengo wa Amoxicillin 250 mg - kuchokera ku 32 ma ruble.
Zosungidwa zamankhwala
Mankhwalawa amasungidwa kutentha mpaka + 25 ° C.
Tsiku lotha ntchito
Zaka zitatu
Wopanga
Mankhwalawa amapangidwa ku Russia.
Ndemanga
Valentina, wazaka 52, Yalta
Ndinafunika kusiya maantibayotiki, chifukwa amandiyambitsa matenda.
Elena, wazaka 27, Rostov
Mankhwala otsika mtengo komanso othandiza. Anali mwana wanga wamwamuna yemwe adatenga pomwe adatseka makutu ake. Kutupa kunachokapo mwachangu, palibe zomwe zinkachitika.
