Matenda a shuga ndi matenda oopsa, chifukwa mankhwalawa amagwiritsidwa ntchito mitundu ingapo ya mankhwala, kuphatikizapo Novoformin. Mankhwalawa ndi a gulu la Biguanides ndipo cholinga chake ndicholembetsa shuga.
Mankhwalawa amalimbikitsidwa kwa odwala omwe ali ndi matenda a shuga 2 omwe ali onenepa kwambiri ngati chithandizo cha zakudya sichokwanira.
Kuphatikiza apo, Novoformin imakonda kutumikiridwa limodzi ndi jakisoni wa insulini ngati wodwala akudwala osati kunenepa kwambiri, komanso chifukwa chachiwiri cha insulin.
Mawonekedwe ndi mawonekedwe a mankhwalawa
Novoformin ndi wa gulu la mankhwala a hypoglycemic operekera pakamwa.
Njira yayikulu yoperekera mankhwala ndi mapiritsi oyera ozungulira. Kapangidwe kake ndi biconvex; pali chiopsezo kumbali imodzi ya mapiritsi.
Chofunikira chachikulu cha mankhwalawa ndi metformin hydrochloride. Kutengera ndende, mitundu iwiri ya mapiritsi imapangidwa: 500 mg ya yogwira ndi 850 mg. Omwe amachokera ku mankhwalawa ndi awa:
- polyethylene glycol,
- povidone
- sorbitol
- magnesium wakuba.
Zosiyanasiyana za mankhwalawa zimasiyananso mtundu wamtundu wa chipolopolo: amatulutsa mapiritsi ndi mapiritsi a nthawi yayitali, komanso filimu kapena enveloping.
Mankhwala ndi a gulu la Biguanides. Zotsatira zazikulu za Novoformin ndi hypoglycemic, i.e., zimathandiza kuchepetsa kuchuluka kwa shuga m'magazi a m'magazi. Metformin imatha kuchepetsa mapangidwe a glucose mu hepatocytes, amachepetsa mphamvu ya kuyamwa kwa glucose. Nthawi yomweyo, mankhwalawa amathandizira kugwiritsidwa ntchito kwa shuga ochulukirapo komanso chidwi cha minofu kuti insulin. Ngakhale izi, Novoformin sikuti imabweretsa mavuto a insulin kwambiri ndipo samayambitsa zotsatira za hypoglycemic.
Mphamvu ya mankhwalawa imawonetsedwa pang'onopang'ono popanda insulin. Mphamvu ya mankhwalawa amasiyana mosiyanasiyana malinga ndi mawonekedwe ake. Chifukwa chake, mapiritsi wamba amachititsa kuchepa kwa cholesterol, IG ndi LDL. Mankhwala omwe akhala akuchita kwa nthawi yayitali, m'malo mwake, samakhudzanso cholesterol ndi LDL, koma nthawi zina amatha kuwonjezera kuchuluka kwa TG.
Kuphatikiza apo, mankhwalawa amathandizira kukhazikika kwa kulemera kwa odwala omwe ali ndi matenda a shuga, ndipo nthawi zina pamakhala kuchepa pang'ono kwa mafuta m'thupi. Nthawi zambiri amagwiritsidwa ntchito ngati munthu amachepetsa thupi, ngakhale patakhala kuti alibe matenda a shuga.
Kuyamwa kwa mankhwalawa kumachokera m'mimba. The bioavailability wa mlingo wa Novoformin mpaka 60%. Mankhwala amatha kudziunjikira mthupi - makamaka minyewa, impso, chiwindi ndi ma gasi a salivary. Kuzindikira kwakukulu kumatheka pafupifupi maola awiri. Kuchoka kwa mankhwalawa kumachitika mosasinthika kudzera impso. Kuthetsa nthawi ya theka la yogwira mankhwala ndi maola 6.5
Kuchulukitsa kwa Novoformin ndikotheka, koma nthawi zambiri kumachitika ndi vuto laimpso. Kuchokera mthupi, mankhwalawa amamuchotsa mkodzo.
Malangizo ogwiritsira ntchito mankhwalawa
Musanayambe kumwa mankhwalawa, ndikofunikira kuti muzolowere malangizo a mankhwalawa kuti mugwiritse ntchito Novoformin kuti mtsogolo musakhale ndi zosakondweretsa.
Mlingo komanso muyezo wa mankhwala ndi amodzi amodzi pa wodwala aliyense. Tengani mapiritsi a 500 mg a yogwira ntchito akulimbikitsidwa kuti ayambe ndi mapiritsi a 1-2 patsiku, ndiye kuti osapitirira 500-1000 mg. Pakupita pafupifupi milungu 1.5-2 chithandizo, kuchuluka kwa mankhwalawa ndikotheka, ngakhale izi zimadalira kuchuluka kwa shuga m'magazi. Kuti mukhale ndi vutoli, mulingo wambiri wa mapiritsi a 3-4 a Novoformin akulimbikitsidwa, okwanira sayenera kupitilira mapiritsi 6.
Mapiritsi a Novoformin 850 mg amayamba kumwa ndi piritsi limodzi tsiku lililonse. Pambuyo pa masabata 1.5-2, potengera kuchuluka kwa shuga m'magazi, chisankho chimapangidwa pakuwonjezereka kwapang'onopang'ono kwa mlingo. Mlingo wokwanira wa mankhwalawa sayenera kupitirira 2,5 g.
Miyezo imeneyi imalimbikitsidwa kwa achikulire. Kwa okalamba, tikulimbikitsidwa kuchepetsa kuchuluka kwa mapiritsi 2 (osapitirira 1000 mg). Komanso, mankhwalawa amachepetsa ndikusokonezeka kwakukulu kwa metabolic m'thupi.
Ndikofunika kumwa mankhwalawo ndi chakudya kapena mukangodya. Mapiritsi amatha kutsukidwa, koma kuchuluka kwa madzi kuyenera kukhala kochepa. Popeza zotsatira zoyipa za mankhwalawa zimatha kuchitika, mlingo wonse wa tsiku ndi tsiku umalimbikitsidwa kuti uugawidwe m'magawo awiri omwewo mu Mlingo wa 2-3.
Ngati wodwala watchulidwa mankhwalawa Novoformin limodzi ndi insulin (Mlingo watsiku ndi tsiku wosakwana 40), ndiye kuti momwemo malamulowo ndi omwewo. Potere, ndizovomerezeka kuti pang'onopang'ono muchepetse mulingo wa insulin, osaposa magawo 8, kamodzi pakapita masiku awiri. Ngati wodwala amakakamizidwa kumwa insulin yoposa 40 ya insulin tsiku lililonse, ndiye kuti kuchepetsa magazi kumavomerezedwanso, koma osavomerezeka kuti azichita yekha. Nthawi zambiri, kuchepetsa insulini kumachitika mu chipatala, mogwirizana ndi njira zonse zofunika kuzisamalira.
Mankhwalawa ali ndi zifukwa zingapo zotsutsana:
- Matenda a chiwindi, impso.
- Myocardial infaration mu shuga.
- Kusalolera payekha kwa metformin kapena zigawo zina za mankhwala.
- Hyperglycemic chikomokere.
- Zakudya zama calori zochepa (zama caloric kudya zosakwana 1000 kcal / tsiku).
Kuphatikiza apo, mankhwalawa sanalembedwe masiku awiri asanachitike opaleshoni iliyonse komanso mayeso omwe amasiyana ndi zomwe ayodini amapatsidwa.
Contraindication poika mankhwala ndi pakati.
Pakukonzekera kutenga pakati, komanso pakati pa mankhwala atangoyamba kumwa, mankhwalawa ndi Novoformin ayenera kusiyidwa.
Ndemanga ndi mtengo wa mankhwalawo
Ndemanga za mankhwala a Novoformin ndi abwino, onse pakati pa madokotala komanso pakati pa odwala. Endocrinologists omwe asiya ndemanga zawo akuti akhala akuwapatsa mankhwala kwa chaka chopitilira chaka chimodzi. Mankhwala othandiza makamaka amawaganizira odwala omwe ali ndi kunenepa kwambiri (omwe ali ndi BMI yoposa 35). Zimathandizira kuchepa kwamafuta ochulukirapo, ngakhale kuti akwaniritse zomwe zimafunika kutsatira zakudya komanso kuchepetsa kudya komwe kumakhala ndi shuga.
Malinga ndi ndemanga, mankhwalawa a Novoformin ali ochepetsetsa kwambiri pakati pa biguanides. Mankhwalawa amathandizanso kuchepetsa misempha ya magazi. Odwala omwe ali ndi kunenepa kwambiri, chizindikiro ichi chatsika ndi 1.5% osamwa mankhwala ena owonjezera ndi insulin.
Ubwino wa mankhwalawo umaphatikizapo mtengo wake: kutengera mzindawu ndi mankhwala, mankhwalawa amatha kutengera mitundu ya ma ruble 100-130.
Kuphatikiza pa ndemanga zabwino, mankhwalawa adalandira ambiri osalimbikitsa. Odwala ena sanawone kusintha kulikonse, ngakhale atakhala nthawi yayitali. Madokotala ena amagwirizana nawo: amakhulupirira kuti Novoformin ndiwofowoka kwambiri kuposa ma analogues, monga Glucofage kapena Siofor.
Mankhwala othandiza, ma endocrinologists amalangizidwa kuti asankhe mitundu ya mankhwala:
- Metformin (chinthu chachikulu),
- Chikwanje,
- Siofor
- Forin Pliva,
- Sofamet
- Metfogamma.
Odwala ena omwe amamwa mankhwalawa amadandaula za mawonekedwe a mankhwalawa:
- kupweteka kwambiri pamimba
- nseru
- kusowa kwa chakudya
- kusokoneza kwam'mimba,
- ziwengo
Mankhwalawa atha kugulidwa ku mankhwala aliwonse, koma pokhapokha ngati mwalandira mankhwala.
Imwani mankhwalawo mosamala mogwirizana ndi malangizo, kupewa bongo.
Kuchulukitsa kuchuluka kofunikira kwa mankhwalawa kumatha kuyambitsa zovuta zina. Chifukwa chake, kumwa mankhwala aliwonse a gulu la Biguanide (kuphatikiza Novoformin) kungayambitse lactic acidosis - mkhalidwe wamavuto omwe ungayambitse imfa. Zizindikiro za lactic acidosis ndi kupweteka kwa minofu, chidwi, kugona, kutsika kutentha kwa thupi, komanso nseru.
Ngati zizindikiro zilizonse za lactic acidosis zikuwoneka, ndikofunikira kusiya kumwa Novoformin ndikugoneka m'chipatala mwansanga.
Ndi mankhwala ati omwe angagwiritsidwe ntchito m'malo mwa Noformin a shuga? Kanemayo munkhaniyi ayankhula za izi.
