Glucophage Long: Malangizo a mtundu wa 2 shuga

Glucophage Long ndi amodzi mwa mitundu ya mankhwala omwe amadziwika kuti amachepetsa shuga, omwe amagwiritsidwa ntchito mosamala pochiza matenda osokoneza bongo omwe samatengera shuga.

Prefix Long imawonetsa kukhalapo kwa phale lomwe limatenga nthawi yayitali, mosiyana ndi kukonzekera kwanthawi zonse kwa Glucofage.

Mankhwala onse omwe alipo omwe amagwiritsidwa ntchito pa matenda a shuga a 2 amatha kugawidwa m'magulu otsatirawa:

• ena mwa mankhwalawa ali ndi phindu pa machitidwe a kapamba, kukakamiza thupi kupanga insulin yambiri;
• ena amachepetsa kukana kwa insulini mwa wodwala, kukulitsa chidwi cha maselo ndi minyewa yake kumadzi.

Mankhwala Glucofage Long (kuchitapo kanthu nthawi yayitali) amathandizanso kuchepetsa matenda a shuga panthawi yopanga matenda a shuga komanso amagwira ntchito ngati njira yolembera kukokana ndi insulin.

Kodi mankhwalawa amagwira ntchito bwanji, kodi ndimofunika kudya ndikumwa mankhwala, ndipo Glucofage Long imalembedwa?

Kupanga, mawonekedwe omasulira, mawonekedwe a pharmacological

Mankhwala Glucofage Long ndi gawo limodzi mwa gulu la mankhwala a greatuanide omwe amagwiritsidwa ntchito mosamala pochiza matenda osokoneza bongo omwe samatengera insulin.

Woimira gulu la Biguanides - metformin hydrochloride amachita ngati chinthu chachikulu chogwira ntchito.

Mankhwalawa ndi mankhwala ochepetsa shuga omwe amalola kuti azisintha kuchuluka kwa shuga, komanso kuyimitsa kukhazikika kwa zovuta zingapo zomwe zimachitika ndi chitukuko cha matenda a shuga.

Ubwino wopeza mapiritsi atulutsidwe otere ali motere:

1. Zotsatira zake pakuchepetsa kukana kwa insulin mwa anthu. Metformin hydrochloride imatha kuwonjezera kukhudzika kwa maselo ndi minyewa ku glucose wopangidwa ndi kapamba.
2. Amachepetsa mawonetseredwe a hyperglycemia, pomwe samathandizira pakukula kwa hypoglycemia, ngakhale mwa anthu athanzi. Njira yochepetsera shuga imachitika pamlingo wokhazikika ndipo sizikupita patsogolo. Ndiye chifukwa chake, chidachi chikuyamba kutchuka pakati pa aliyense amene akufuna kuchepetsa thupi, mosasamala kanthu za kupezeka kwa mtundu wa insulin wokha.
3. Zitha kuwonetsa ntchito yodzitchinjiriza pankhani yaubongo kuteteza kukalamba.
4. Mosangalatsa zimakhudza mitsempha yamagazi ndi mitsempha. Chifukwa chake, mothandizidwa ndi metformin, kukula kwa mitsempha ya mitsempha, kulephera kwa mtima, matenda oopsa, komanso kupimitsa mtima kwamitsempha. Ndizovuta zina zomwe zimakonda kukhala zovuta kwa odwala omwe ali ndi shuga yayitali.
5. Amachepetsa mwayi wokhala ndi khansa.
6. Zimalepheretsa kukula kwa mafupa a anthu odwala matenda ashuga. Makamaka nthawi zambiri, azimayi amakhala ndi vuto la mafupa osaneneka atasiya kusamba, popeza pali kuchepa kwakukulu kwa mahomoni - estrogen.
7. Zimakhala ndi phindu pa cholesterol, kuchepetsa zoyipa ndikuwonjeza zabwino.
8. Zokhudza bwino chithokomiro cha chithokomiro.
9. Imathandizira kuchepetsa njira ya peroxidation yamafuta.
10. Ili ndi ntchito yoteteza mokhudzana ndi njira yopumira.

Kusiyana kwakukulu pakati pa mankhwala a piritsi Glucofage Long ndizowonetsera zazotsatira monga:

• pali njira yogwirira ntchito ndikupanga makondedwe amafuta a thupi;
• chakudya chamagulu omwe amalowa mthupi limodzi ndi chakudya amalowetsedwa m'makoma am'mimba kwambiri;
• pali kukondoweza ndi kutsegula kwa glucose processing ndi minofu minofu.

Wopanga mankhwalawa ndi kampani yamankhwala Merck, yomwe katundu wake amakhala ku France ndi Germany. Ichi ndichifukwa chake, mtengo wa mankhwalawa Glucophage Long ukhoza kusiyana kwambiri ndi mankhwala apakhomo, omwe ali ndi chimodzimodzi ndi Glucophage Long.

Ma pharmacological mawonekedwe a kumasulidwa kwa mankhwalawa ndi mapiritsi akukonzekera mu chipolopolo. Kuphatikiza pa metformin hydrochloride, kuphatikiza kwa mankhwalawo ndi prefix yayitali kumaphatikizanso zinthu zina zowonjezera mu mawonekedwe a sodium carmellose, hypromellose, ndi magnesium stearate.

Malangizo ogwiritsira ntchito mankhwalawa

Kuti mudziwe mankhwala omwe ali, komanso Mlingo wofunika wodwala amatenga kokha adokotala.

Kutengera mankhwalawa komwe dokotala wakupangira adakupatsani mankhwala, mtundu wake wa mankhwalawo udzasintha.

Mpaka pano, m'mafakitala mutha kugula mankhwala mumagawo awiri akuluakulu - ndi kuchuluka kwa 500 ndi 750 mamilimita a yogwira.

Mukamatenga kuchuluka kwa nthawi yayitali, nthawi komanso mfundo (nthawi) ya makonzedwe ndi kuchuluka kwa mankhwalawa zimatsimikiziridwa ndi katswiri wazachipatala yemwe amasunga mbiri yachipatala ya wodwala.

Mukamagwiritsa ntchito mankhwala, ndikofunikira kutsatira malangizo (malangizo ogwiritsira ntchito):

• imwani pakumwa kamodzi patsiku ndi madzi pang'ono mukamaliza kudya.
• ngati kuli kotheka, dokotala amatha kukhazikitsa mankhwala awiri.
• Mlingo umagwiritsidwa ntchito payekhapayekha kwa wodwala aliyense payokhapayokha pofotokozera za kuchuluka kwa shuga m'magazi.
• Monga lamulo, chithandizo choyambirira chimakhala piritsi limodzi lokhala ndi zinthu zochepa zogwira ntchito madzulo.

Pali milandu pamene wodwalayo adayamba kumwa mankhwalawo ndi nthawi yochepa yopuma ya zomwe zimachitika, pambuyo pake amamuika mankhwala kuti agwiritsidwe ntchito kwa nthawi yayitali. Kenako kuyambika kwa mankhwalawo kuyenera kukhala kofanana ndi kuchuluka kwa mankhwalawa omwe wodwalayo adatenga m'mbuyomu.

Kugawilidwa kwa Mlingo womwe ulipo kumayenera kuchitika pang'onopang'ono, pafupifupi masiku 10 aliwonse pa gramu imodzi yogwira ntchito. Pafupipafupi, kumwa kwa ma milligram miliyoni 1,500 kumagwiritsidwa ntchito, ndipo kugwiritsa ntchito mankhwalawo kuli kofanana ndi magalamu awiri a chinthu chomwe chikugwira ntchito.

Ngati wodwala wasankha kusiya kugwiritsa ntchito mankhwalawa, dokotala wopezekayo ayenera kudziwitsidwa za izi.

Ngati zikuchitika kuti mudadumpha piritsi, palibe chifukwa chobwerezera.

Zotsatira zoyipa mukamagwiritsa ntchito mankhwala

Kuwonetsedwa kwa zoyipa zomwe zimachitika kumatha kuonedwa m'magulu ena a odwala. Tiyenera kudziwa kuti zoyipa zotere zimachitika mosiyanasiyana malinga ndi zomwe ziwalo zamkati sizinachite pakamwa mankhwala m'thupi.

Nthawi zambiri, pamakhala zotsatirapo zovuta pamimba. Wodwalayo amatha kumva kuyandikira mseru, komwe kumayendetsedwa ndi kusanza, kupweteka pamimba. Kuphatikiza apo, zotsatira za mankhwala apiritsi zimaphatikizanso kuchepa kwakudya, ndikuwonetseratu zovuta, munthu samatha kumva njala konse. Nthawi zina, anthu amafotokoza malilidwe osangalatsa a zitsulo pakamwa pawo. Monga lamulo, zizindikiro zotere nthawi zambiri zimayamba kumayambiriro kwa matendawo, pambuyo pake zimayamba kuchepa. Kuti ziwalo zam'mimba zitha kuyamwa pang'ono pang'onopang'ono pomwa mankhwalawo, mlingo wake uyenera kuwonjezeka pang'onopang'ono.

Pafupipafupi, kuwonjezereka kwa ntchito ya chiwindi komanso kufalikira kwa matenda osiyanasiyana a ziwalo.

Thupi lawo siligwirizana pa kumwa mankhwalawa limatha kuwoneka ngati kuyabwa kwa khungu, khungu lawo kapena kutentha kwake.

Chimodzi mwazinthu zowopsa zomwe zimachitika ndi lactic acidosis. Chifukwa chake, kagayidwe ka wodwala, komwe odwala matenda ashuga amalephera chifukwa cha kupangika kwa mapangidwe, angayankhe ku chithandizo chamankhwala. Chiwopsezo cha chiwonetsero chake pamaso pa aimpso a pathologies mu odwala chimawonjezeka. Chiwopsezo cha lactic acidosis imachulukitsidwa ndi zinthu monga kudya zosayenera (kudya mosasamala kapena kusala), kumwa mowa. Zizindikiro zazikulu za izi zitha kukhala kumverera kwa kufooka kwa thupi, kusazindikira, minofu kukokana, asthenia ndi hypothermia.

Kuphatikiza apo, ziyenera kukumbukiridwa kuti kusatsatira malamulo omwe amalimbikitsidwa kungathandizenso kukulitsa lactic acidosis. Pamaso pa izi, mankhwalawa ayenera kuyimitsidwa pomwepo ndipo wodwala amayenera kuchipatala.

Monga mankhwala a bongo ndi kuwonetsa lactic acidosis, symptomatic mankhwala ndi hemodialysis ndi mankhwala.

Kodi milandu ndi yoletsedwa liti?

Ndi zoletsedwa kusankha payokha mankhwalawa.

Tiyenera kukumbukira kuti mapiritsi a Glucofage Long ayenera kulembedwa kwa anthu omwe ali ndi vuto la matenda osokoneza bongo kuti azitha kusintha kuchuluka kwa shuga m'magazi ndikuwonjezera chidwi cha insulin yotulutsidwa pamaselo a cellular.

Mankhwalawa ali ndi chiwerengero chambiri chotsutsana ndi zomwe amagwiritsidwa ntchito, zomwe zimafunikira kuti muzidziwika bwino musanayambe mankhwala.

Kumwa mankhwala ndikoletsedwa pamaso pa zinthu izi:

1. Amayi pa nthawi yobereka komanso mkaka wa m`mawere, chifukwa cha kusowa kwa deta yokwanira pakukonzekera kwa mwana wosabadwa ndi mwana. Kuzindikira kochepa komwe kunachitika sikunawonetse vuto pa kukula ndi ntchito yofunika ya mwana. Komabe, izi sizokwanira kungomwa mankhwalawo motetezeka.
2. Ngati pali kuwonjezeka kwa kumverera kwa chimodzi mwazigawo za mankhwala. Kulephera kutsatira izi kungapangitse kukula kwa mayankho osiyanasiyana munthawi zosiyanasiyana.
3. Ngati wodwala akuvutika ndiimpso ntchito.
4. Pali kukhalapo kwa ketoacidosis.
5. Anthu odwala matenda ashuga kapena glycemic coma.
6. Kulimbitsa thupi, komwe kumayendetsedwa ndi kusanza kwambiri kapena kutsegula m'mimba, ndipo kumatha kuyambitsa vuto laimpso.
7. Pamaso pa kuwonekera kwa njira zosiyanasiyana za pathological mu magawo osiyanasiyana a chitukuko, zomwe zimapangitsa kukhala minofu yamtundu wa hypoxia.
8. Pa kuvulala kwambiri kapena kuchitapo kanthu opaleshoni.
9. Ana osakwana zaka zambirimbiri.

Kuphatikiza apo, muyenera kumwa mankhwalawa mosamala ndi mankhwala ena. Pali zosankha pamene mankhwala othandizira, omwe ali gawo la mankhwala Glucofage Long, sagwirizana ndi magulu ena a mankhwala. Dokotala wopezekapo ayenera kudziwitsidwa za kugwiritsa ntchito mankhwala ena onse.

Mndandanda wa mankhwala Glyukofazh Long

Ndemanga ya Glucophage Long imawonekera mu lingaliro la odwala ndi akatswiri azachipatala. Monga lamulo, amawonetsa kulekerera kwabwino kwa mankhwalawa, kupezeka kwake komanso kuchuluka kwabwino kwa shuga m'magazi ake. Nthawi yomweyo, palinso gulu la odwala, lomwe likuwonetsa kuwoneka kwa zoyipa zosiyanasiyana zakusiyanasiyana kosiyanasiyana.

Mpaka pano, mtengo wa piritsi lamankhwala wokhala ndi mphamvu yayitali uli m'malo osiyanasiyana a ruble 270-300.

Pakhoza kukhala zochitika zina zomwe wodwalayo ayenera kuyang'ana m'malo mwa mankhwalawa Glucofage Long. Pankhaniyi, dokotala wopezekapo ayenera kulembera wodwalayo mankhwala omwewo chimodzimodzi - yochepa kapena yayitali. Monga lamulo, kusintha kwa mankhwalawa kumachitika malinga ndi INN yomwe ikupezeka, ndiye kuti, ndi zomwe zimagwiranso ntchito popanga mankhwalawa. Kusiyanako kungakhale mu kuchuluka kwa zigawo zothandizira kapena kusiyanasiyana.

Mwa mankhwala omwe ali ofanana ndi Glucophage Long, munthu amatha kudziwa mankhwalawa monga Glyformin Prolong, Diaformin OD, Formin Pliva.

Momwe mungagwiritsire ntchito Glucophage pa matenda a shuga afotokozedwa ndi katswiri muvidiyoyi.