Siofor: contraindication ndi zotsatira zoyipa

Siofor ndi piritsi la antidiabetesic. Wothandizira wake ndi metformin.

Chidacho, monga mankhwala ena aliwonse, chili ndi zotsutsana zingapo. Ngati mungaganize zoyamba kutenga Siofor, ndikofunikira kuphunzira malangizo ndi kuwunika kwa odwala.

Siofor amadziwika kuti ndi mankhwala otchuka polimbana ndi matenda ashuga a 2. Mankhwala amatengedwanso kupewa. Siofor imakulitsa chidwi cha maselo pazovuta za insulin, ndiye kuti, amachepetsa kukana kwa insulin.

Cholinga cha Siofor

Siofor 850 imazindikiridwa molakwika ndi anthu ambiri ngati njira, cholinga chake chachikulu ndicho kuchepa thupi.

Cholinga chachikulu cha mankhwalawa ndikuchepetsa shuga la magazi mwa anthu omwe ali ndi matenda a shuga. Kunenepa kwambiri muzochitika izi ndizofala kwambiri, nthawi zambiri kumalumikizidwa ndi kuchuluka kwa shuga m'magazi komanso kuchepa kwa kagayidwe kazinthu.

Mankhwalawa ali ndi metformin, yomwe imachepetsa shuga ya magazi ndikuphwanya zotsalira za cholesterol. Chifukwa chake, odwala matenda ashuga amatha kuchepa thupi. Anthu athanzi nthawi zina amagwiritsanso ntchito mankhwalawa.

Ndemanga za Siofor za anthu athanzi omwe akufuna kuchepa thupi ndizovuta, chifukwa popanda kulankhula ndi dokotala ndikutsatira malangizowo, kuwonda sikuchitika, ndipo zotsatira zoyipa zimachitika.

Ngati munthu alibe kuchuluka kwamphamvu kwa shuga m'magazi, ndiye kuti kuchepa kwambiri m'magazi kungakhale koopsa, mpaka matenda amtundu wa endocrine komanso mawonekedwe a hypoglycemic coma, shuga atatsika mtengo wotsika kwambiri.

Mankhwala Siofor ali ndi mawonekedwe awa:

• Glycon.
• Bagomet.
• Glucophage.
• Glformin.
• Vero-Metformin.
• Glycomet 500.
• Dianormet.
• Langerine.
• Methadiene.
• Glyminfor.
• Metfogamma 1000.
• Dormin
• Metospanin.
• Metformin.
• Metfogamma.
• Metfogamm 500.
• NovoFormin.
• Metformin-BMS.
• Siofor 500.
• Metformin Richter.
• Sofamet.
• Fomu.

Pharmacological zochita ndi zikuchokera mankhwala

Siofor ndi mankhwala omwe amapangidwa kuti achepetse shuga m'magazi mwa anthu omwe ali ndi mtundu wachiwiri wa shuga. Odwala otere nthawi zambiri amakhala onenepa kwambiri.

Mu malangizo omwe akupangidwira chida palibe chidziwitso chakugwiritsa ntchito anthu athanzi kuti achepetse thupi. Metformin ikalowa m'thupi la munthu wodwala matenda ashuga, zimakhudza maselo am'misempha kuti azitha kutulutsa shuga wowonjezera omwe ali ndi magazi.

Izi zimagwira ntchito makamaka kwa thupi la anthu odwala matenda ashuga a 2. Kwa iwo omwe alibe matenda otere, kugwiritsa ntchito mankhwalawa kumakhala kopanda ntchito. Zomwezo zimagwiranso ntchito pa mankhwala a Siofor.

Mlozera wa digito, womwe umayenera pambuyo pa dzina la zilembo, ndiye mtundu wake wa mlingo. Pakadali pano, mankhwala a Siofor amagulitsidwa pamiyeso:

• 1000 mg
• 850 mg
• 500 mg

Njira yamachitidwe

Mankhwala amachepetsa kufunika kwa shuga m'magazi, komanso chisonyezo chake mukatha kudya. Metformin sikukakamiza maselo a pancreatic beta kuti apange insulin yochulukirapo, zomwe zikutanthauza kuti hypoglycemia siziwoneka.

Njira yochepetsera kuchuluka kwa shuga mukamagwiritsa ntchito Siofor ndikuwonjezera mphamvu ya maselo kutenga shuga kuchokera m'magazi. Kuphatikiza apo, insulin sensitivity ya cell membrane imakulira.

Siofor amachepetsa kuyamwa kwa chakudya kuchokera m'matumbo ndi m'mimba. Mafuta acid oxidation amathamangitsidwanso ndipo anaerobic glycolysis imakonzedwa. Siofor mu matenda a shuga amachepetsa njala, yomwe imathandizanso kuchepetsa kunenepa. Mwa anthu omwe alibe shuga, mapiritsi awa samachepetsa kuchuluka kwa shuga. Zochita za Siofor pankhaniyi sizikupezeka.

Anthu odwala matenda ashuga omwe amatenga Siofor ndikutsatira zakudya zapadera nthawi zina amachepetsa thupi. Izi zimatsimikizira nthano kuti metformin ndi njira yochepetsera kunenepa.

Ngati mankhwalawa amachepetsa thupi, akhonza kupatsidwa malangizo kwa anthu onse odwala matenda ashuga.

Tsoka ilo, anthu odwala matenda a shuga omwe amagwiritsa ntchito Siofor kwa nthawi yayitali kuyambira 500 mpaka 850 mg kangapo patsiku samazindikira kwambiri kuwonda.

Malangizo ogwiritsira ntchito mankhwalawa

Mlingo wa mankhwalawa umaperekedwa ndi adokotala okha. Monga lamulo, kugwiritsa ntchito mankhwalawa kumayamba ndi osachepera 500 mg.

Siofor imayikidwa muyezo woyambirira wa 500 mg / tsiku, pakapita nthawi, kuchuluka kumawonjezeka mpaka mfundo zomwe mukufuna zitheke. Pakatha masiku 10 mpaka 15, mulingo woyenera ukusinthidwa pogwiritsa ntchito chizindikiro cha magazi. Kuwonjezeka kwapang'onopang'ono kwa mlingo kumakhudza chidwi cha kukonzekera kwa kugaya chakudya.

Mlingo wapamwamba wa 0,5-3 g metformin hydrochloride amaloledwa tsiku lililonse, izi zikufanana ndi mapiritsi a Siofor 500 kapena 3 g mpaka 3 mapiritsi a Siofor 1000. Mankhwalawa amatha kugwiritsidwa ntchito katatu patsiku, koma, nthawi zambiri, chithandizo cha shuga chimakhala chokwanira 100 mg kawiri pa tsiku.

Kuti mukwaniritse kukonza bwino shuga, magazi amasakanikirana ndi insulin.

Choyamba, Siofor amapatsidwa 500 mpaka 850 mg kangapo patsiku, pomwe kuchuluka kwa insulin kumadalira kuchuluka kwa shuga m'magazi. Mankhwala ayenera kumwedwa ndi zakudya, osafuna kutafuna, amwe ndi madzi okwanira.

Mlingo wa 500 mg nthawi zambiri umagwiritsidwa ntchito ngati pali prediabetes kapena munthu amayamba kuchepa thupi. Ngati wodwala matenda ashuga alibe zotsatira zoyipa pambuyo pa sabata yogwiritsira ntchito, kuchuluka kwa mankhwalawa kumawonjezera, mwachitsanzo, Siofor 850 imagwiritsidwa ntchito kapena piritsi lina la Siofor 500 limawonjezeredwa maola 12 pambuyo pa woyamba. Sabata iliyonse, 500 mg ya metformin imawonjezeredwa pang'onopang'ono, koma ndikofunikira kuyang'anira nthawi zonse kukhalapo kapena kusakhalapo kwa zotsatira zoyipa.

Ngati kuchuluka kwa mankhwalawa a Siofor kumawonjezeka, ndiye kuti zovuta zake zimakhala zofunikira kwambiri. Kenako muyenera kuchepetsa kuchuluka kwa kuchuluka kwapita. Popita nthawi, muyeneranso kuyesetsa kuwonjezera kuchuluka kwa mankhwalawa kukhala othandiza kwambiri.

Ngati mulingo woyenera wa mankhwalawa ndi 500 mg, waledzera 1 nthawi yamadzulo, motero kuchepetsa chiopsezo cha mavuto. Ngati Mlingo uli wa 1000 mg patsiku, ndiye kuti muyezo umagawidwa muyezo waukulu.

Ndikofunika panthawi yamankhwala osokoneza bongo a gululi kuti muzichita mayeso osonyeza momwe chiwindi ndi impso zimagwirira ntchito. Makamaka, izi ziyenera kuchitika:

1. kuyezetsa magazi konse
2. mayeso a biochemical magazi (michere ya chiwindi, creatinine).

Mndandanda wazopondera

Siofor 850 ndi mankhwala amphamvu omwe samalimbikitsidwa kuti azigwiritsa ntchito popanda kufunsa dokotala.

Ngati lingaliro likutenga Siofor, ndiye kuti zotsutsana ndi motere:

• chidwi chapamwamba pazinthu zomwe zimapangidwa,
• zovuta za endocrine,
• kulephera kupuma
• mtundu 1 shuga
• chiwindi ndi matenda a impso,
• kuvulala kwambiri
• myocardial infaration pa siteji yowonjezera,
• matenda opatsirana opatsirana
• ntchito zaposachedwa
• zotupa pa oncological,
• uchidakwa wambiri,
• mimba
• Zakudya zopatsa mphamvu zochepa
• zaka za ana
• yoyamwitsa.

Madokotala amamulembera mankhwalawa kwambiri. Siofor 850 iyenera kumwedwa mosamala:

1. anthu opitilira 60
2. ana ochepera zaka 12
3. anthu omwe nthawi zambiri amakhala ndi masewera olimbitsa thupi.

Pali zovuta zowonjezera chifukwa chotenga Siofor, iyi ndi lactic acidosis. Vutoli limafunikira kuchipatala mwachangu ndi chithandizo chamankhwala osamala kwambiri.

Lactic acidosis ili ndi zizindikiro izi:

• dontho lakuthwa,
• kugunda kwamtima
• kulephera kupuma
• kusokonezeka kwa mtima
• kufooka ndi kugona,
• dontho mu kuthamanga kwa magazi.

Kuchokera ku Siofor pali zovuta zina zomwe zimawonjezeka pambuyo zolimbitsa thupi mwamphamvu. Ponyalanyaza mfundo iyi, azimayi ambiri amayamba kumwa mankhwalawo kuti achepetse thupi, kuphatikiza phwando ndi katundu m'malo olimbitsa thupi kapena dziwe. Chifukwa chake, zotsatira zomwe sizikuyembekezeka sizichitika.

Chifukwa chogwiritsa ntchito Siofor mosaganizira, ndemanga zoyipa zimabuka za mankhwalawa.

Tiyeneranso kudziwa kuti mwayi wa lactic acidosis ukuwonjezeka ngati mumamwa zakumwa zoledzeretsa.

Siofor yoletsa matenda ashuga amtundu wa 2

Popewa kupangika kwa matenda ashuga amtundu wa 2, ndikofunikira kutsatira njira zonse zathanzi. Chifukwa chake, muyenera kuwonjezera zochita zanu zolimbitsa thupi ndikusintha makina azakudya.

Odwala ambiri m'moyo watsiku ndi tsiku samakonda kutsatira malingaliro a moyo. Nkhani yofunikira ndikukupanga njira yopeweretsera matenda a shuga a 2 omwe amagwiritsidwa ntchito ndi Siofor.

Zaka 10 zapitazo, malingaliro ochokera ku American Diabetes Association okhudza kugwiritsa ntchito kwa Siofor popewa matenda oyamba ndi matenda a shuga amawonekera. Kafukufukuyu wasayansi adatenga zaka zitatu, ndikuthokoza kwake kudadziwika kuti kugwiritsa ntchito Glucophage kapena Siofor kumachepetsa mwayi wopanga matendawa ndi 31%.

Ngati munthu wasinthiratu ndi moyo wathanzi, ndiye kuti chiopsezo chidzagwa ndi 58%. Kugwiritsa ntchito mapiritsi a metformin ngati njira yodzitetezera akulimbikitsidwa kwa odwala omwe ali pachiwopsezo chachikulu chotenga matenda a shuga.

Gululi limaphatikizapo anthu azaka zosaposa 60 omwe onenepa kwambiri, omwe ali ndi vuto limodzi kapena zingapo, zomwe ndi:

1. glycated hemoglobin - oposa 6%,
2. ochepa matenda oopsa
3. Anachepetsa cholesterol yayikulu kwambiri m'magazi,
4. triglycerides
5. lembani matenda ashuga 2 mwa achibale,
6. kulemera kwamphamvu kwa thupi kupitilira 35.

Odwala oterewa amatha kutenga Siofor kuti apewe matenda a shuga. Mlingo mu nkhani iyi amachokera ku 250 mpaka 850 mg kawiri pa tsiku. Pakadali pano, Siofor kapena mitundu yake, Mankhwala Glucofage ndi mankhwala okhawo omwe amawerengedwa ngati prophylactic motsutsana ndi matenda a shuga.

Kuwongolera ntchito ya impso ndi chiwindi kuyenera kukhala kusanachitike ndalama ndi metformin kenako miyezi isanu ndi umodzi. Kuphatikiza apo, ndikofunikira kuyang'ana kuchuluka kwa magazi lactate kawiri pachaka. Mankhwalawa a shuga mellitus osakanikirana ndi Siofor omwe amachokera ku sulfonylurea, kuthekera kwakukulu kwa hypoglycemia kumawonekera.

Kuwunikira pafupipafupi kuchuluka kwa shuga m'magazi kumafunika, mpaka kangapo patsiku. Chifukwa cha chiwopsezo cha hypoglycemia mwa odwala omwe amatenga Glucofage 850 kapena Siofor, sizikulimbikitsidwa kuti azichita zinthu zomwe zimafunikira chidwi chochulukirapo komanso ma psychomotor reaction.

Mtengo

Pakadali pano, mtengo wa mankhwalawo umasiyanasiyana kutengera mtundu wake. Monga lamulo, phukusi la Siofor 850 limadya pafupifupi ma ruble 350.

Katswiri wa kanemayu munkhaniyi anena za Siogor wa hypoglycemic.