Zinc insulin ndi mtundu 1 komanso mtundu wa 2 wa matenda ashuga omwe amabwera poyimitsidwa. Mankhwala osokoneza bongo akhala akuchita insulin kuti cholinga chake chikhale chopanda minofu ina.
Kutalika kwa kuyimitsidwa kwa zinc-insulin pafupifupi maola 24. Monga momwe amakonzera insulini yonse kwanthawi yayitali, mphamvu yake pakhungu sikuwoneka nthawi yomweyo, koma patatha maola awiri jekeseni atayamba kubayidwa. Peak zochita za nthaka insulin amapezeka pakati 7-16 mawola makonzedwe.
Kuphatikizidwa kwa insulin zinc kuyimitsidwa kumaphatikizapo kuyeretsedwa kwambiri kwa insulin ndi insulin chloride, komwe kumalepheretsa mankhwalawo kulowa m'magazi mwachangu kwambiri ndipo potero amawonjezera nthawi yayitali.
Machitidwe
Kuyimitsidwa kwa insulin zinc amakhalanso chakudya, mapuloteni ndi lipid kagayidwe. Ikamamwa, imathandizira kupezekanso kwamitsempha yama cell yama glucose, omwe amathandizira kuti shuga akhale ndi shuga m'thupi. Kuchita kwa mankhwalawa ndikofunikira kwambiri, chifukwa kumathandizira kuchepetsa shuga yamagazi ndikuthandizira kuti isasungidwe nthawi yochepa.
Zulin insulin imachepetsa kupanga glycogen ndi ma cell a chiwindi, komanso imathandizira njira ya glycogenogeneis, ndiko kuti, kutembenuka kwa glucose ku glycogen ndi kuchuluka kwake mu minyewa ya chiwindi. Kuphatikiza apo, mankhwalawa amathandizira kwambiri lipogenis - njira yomwe glucose, mapuloteni ndi mafuta amakhala mafuta acids.
Mlingo wa mayamwidwe m'magazi ndi kuyambika kwa mankhwalawa zimatengera momwe insulin idathandizira - subcutaneally kapena intramuscularly.
Mlingo wa mankhwalawa amathanso kukhudza kukula kwa zochita za zinc.
Malangizo ogwiritsira ntchito mankhwalawa
Kugwiritsa ntchito mankhwala kuyimitsidwa kwa nthaka insulin jekeseni tikulimbikitsidwa mankhwalawa mtundu 1 matenda a shuga, kuphatikiza ana ndi akazi udindo. Kuphatikiza apo, chida ichi chitha kugwiritsidwa ntchito pochiza matenda a shuga 2, makamaka chifukwa chosagwiritsa ntchito mapiritsi ochepetsa shuga, makamaka ochokera ku sulfonylurea.
Zulin insulin imagwiritsidwa ntchito kwambiri pothana ndi zovuta za matenda ashuga, monga kuwonongeka kwa mtima ndi mtsempha wamagazi, phazi la matenda ashuga komanso kuwonongeka kwa mawonekedwe. Kuphatikiza apo, ndizofunikira kwa odwala matenda ashuga omwe amachitidwa opaleshoni yayikulu komanso panthawi yochira pambuyo pawo, komanso chifukwa cha kuvulala kwambiri kapena zochitika zam'mutu kwambiri.
Kuyimitsidwa kwa zinc insulin kumapangidwira majakisoni amkati, koma nthawi zina amatha kuthandizira intramuscularly. Mothandizidwa ndi intravenous a mankhwalawa ndi oletsedwa, chifukwa angayambitse matenda a hypoglycemia.
Mlingo wa mankhwala a insulin Zinc amawerengedwa aliyense payekha kwa wodwala aliyense. Monga ma insulin ena omwe akhala akuchita kwakanthawi, amayenera kuperekedwa kamodzi kapena kawiri patsiku, kutengera zosowa za wodwalayo.
Mukamagwiritsa ntchito kuyimitsidwa kwa insulin zinc panthawi yomwe muli ndi pakati, ndikofunikira kwambiri kukumbukira kuti m'miyezi itatu yoyambirira yobereka mwana mkazi akhoza kuchepetsa kufunika kwa insulin, ndipo m'miyezi 6 yotsatira, motsutsana, iwonjezeka. Izi ziyenera kukumbukiridwa powerengera mankhwalawo.
Pambuyo pa kubadwa kwa mwana ndi matenda a shuga komanso pa nthawi yoyamwitsa, ndikofunikira kuyang'anitsitsa kuchuluka kwa shuga m'magazi ndipo ngati kuli koyenera, sinthani mlingo wa insulin.
Kuwunikira mosamala koteroko glucose kuyenera kupitilizidwa mpaka mkhalidwewo utakhazikika.
Mtengo
Masiku ano, kuyimitsidwa kwa insulin ndizosowa kwambiri m'masitolo am'mizinda ya Russia. Izi zimachitika makamaka chifukwa cha kutuluka kwa mitundu yambiri yamakono ya insulin, yomwe idachotsa mankhwalawa m'mashelufu azamankhwala.
Chifukwa chake, ndizovuta kutchula mtengo weniweni wa insulin. M'mafakitala, mankhwalawa amagulitsidwa pansi pa mayina amalonda Insulin Semilent, Brinsulmidi MK, Iletin, Insulin Lente "HO-S", Insulin Lente SPP, Insulin Lt VO-S, Insulin-Long SMK, Insulong SPP ndi Monotard.
Ndemanga za mankhwalawa nthawi zambiri zimakhala zabwino. Odwala ambiri omwe ali ndi matenda ashuga akhala akuwagwiritsa ntchito bwino kwazaka zambiri. Ngakhale m'zaka zaposachedwa akuchitanso zina ndi anzawo amakono.
Analogi
Monga fanizo la zinc insulin, mutha kutcha kukonzekera konse kwa insulin. Izi zikuphatikiza Lantus, Insulin Ultralente, Insulin Ultralong, Insulin Ultratard, Levemir, Levulin ndi Insulin Humulin NPH.
Mankhwalawa ndi mankhwala osokoneza bongo am'badwo waposachedwa. Insulin yomwe ikuphatikizidwa ndi mawonekedwe ake ndi analogue ya insulin yaumunthu yomwe imapezeka ndi ma genetic engineering. Chifukwa chake, sichimayambitsa ziwopsezo ndipo zimalekeredwa bwino ndi wodwalayo.
Makhalidwe ofunikira kwambiri a insulin akufotokozedwa mu kanema m'nkhaniyi.
