Pancreatic autoimmune lesion

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Autoimmune pancreatitis ndi njira yatsatanetsatane, yomwe siiyo kapamba wokha, komanso ziwalo zina zamkati zomwe zimakhudzidwa. Matendawa ndi osowa kwambiri, osamveka bwino, chifukwa chake, zomwe zimayambitsa chitukuko sizikudziwika.

Ntchito zoteteza thupi lathu zimayamba kupanga ma antibodies enaake omwe amasokoneza kapangidwe ka maselo kapamba, amakhala ndi vuto la ndulu, impso, mapapo, m'mimba, ndi m'mimba.

Matendawa amatchulidwa ndi ma pathologies omwe amadziwika ndi njira yovuta. Amakhala kuposa miyezi isanu ndi umodzi. Nthawi zambiri kukhathamiritsa kumapezeka, kuchotsera kumakhala kochepa.

Panthawi yotupa, ndiye kuti, ndikuchulukirachulukira, kumachepa pantchito ya mkati. Talingalirani za zomwe matenda amathandizidwe amakhudzana ndi kuwonongeka kwa kapamba, kapangidwe ka mankhwala.

Chipatalachi

Kutsimikizira kwa kayendedwe ka pathological m'thupi sikumveka. Chifukwa cha kuphwanya, chitetezo champhamvu chimayamba kuukira maselo ake omwe. Mtundu wa autoimmune wa pathology nthawi zambiri umaphatikizidwa ndi matenda - Matenda a Sjogren, kusokonezeka kwamatumbo m'mimba.

Matendawa amakhala kwachilengedwe chonse kudzera pakusinthasintha kwakuya, pomwe matenda owopsa amatsatiridwa ndikuchotsedwa. Wodwalayo amakhala ndi zovuta mu 70% ya zithunzi - shuga mellitus, chiwonongeko cha zikondamoyo, mawonekedwe a pseudocysts.

Zimakhala zovuta kukayikira matenda. Nthawi zambiri, zimachitika motsutsana ndi maziko osakhalapo akuwonekera. Nthawi zina mu gawo lowopsa, zizindikiro zazikulu zimakhalapo. Nthawi zambiri odwala amaphunzira za matenda awo mavuto atayamba kale.

Wodwala amatha kukhala ndi izi:

  • Ululu umayamba pamimba, umatha kukhala mphindi zingapo kapena maola angapo. Kukula kwa kupweteka kwapakati.
  • Kuteteza khungu pakhungu ndi mucous nembanemba, kwachilengedwe madzi - malovu kapena misozi. Zimachitika chifukwa cha kusokonezeka kwa kayendedwe ka bile mu duodenum chifukwa chochepetsera ma dancts a pancreatic. Zizindikiro zowonjezera zimaphatikizapo mkodzo wakuda, ndowe zofotokozedwa, zizindikiro za khungu - kuyabwa, kuyaka.
  • Zizindikiro za Dyspeptic. Odwala amadandaula za kutaya mtima, kusanza ndi mseru, kuchuluka kwa mpweya, kuwawa pamkamwa.
  • Pali kuphwanyidwa kwa mapangidwe achilengedwe a chithokomiro, zomwe zimabweretsa kukula kwa matenda a shuga. Chachilendo cha matendawa ndi autoimmune pancreatitis ndikuti zamatsenga zimadziwika ndi njira yabwino komanso kuchira kwathunthu.
  • Emotional lability, kupsinjika mtima, kuchepa kwa ntchito, ndi mawonekedwe ena a asthenic.

Zizindikiro zapadera zitha kuonekanso chifukwa cha kuwonongeka kwa chiwalo china. Mwachitsanzo, ndi kuwonongeka kwa mapapu, kupuma movutikira kumawonekera, kumakhala ndikumverera kosowa kwa mpweya.

Ngati pali zovuta ndi impso, ndiye kuti kulephera kwa impso kumadziwika, mapuloteni amawoneka mkodzo.

Mitundu ya Kutentha kwa Autoimmune Gland

Matenda a autoimmune a kapamba amagawidwa m'mitundu ingapo. Kutengera chithunzi cha mbiriyakale - kusintha kwa kapangidwe ka kapamba kodziwonetsa ndi microscopic diagnostic, mitundu iwiri ya kapamba amadziwika.

Loyamba ndi mtundu wonyezimira wamitsempha. Mtundu wachiwiri ndi mawonekedwe idiopathic a duct-concentric pancreatitis okhala ndi zotupa za granulocytic za epithelial minofu. Kusiyanaku kumangokhala m'mbiri yokha. Mwanjira ina, zimangotsimikizika mu ma labotale okhaokha; palibe njira zina zodziwira.

Pathology imadziwikanso ndi kukhalapo kwa autoimmune pathologies. Pali mitundu iwiri:

  1. Mtundu wakudziwika umapezeka mwa odwala omwe zolephera zina za autoimmune sizipezeka.
  2. Autoimmune pancreatitis syndrome ndi matenda omwe amakula motsutsana ndi maziko a autoimmune pathologies ena.

Kutengera ndi malo a chotupa, kapamba amatha kukhala a mawonekedwe osokoneza - gawo lonse lamkati ndi mtundu wotsoguka zimakhudzidwa - pali zotupa za magawo pancreatic, pazithunzi zambiri, kutupa kumakhala m'mutu.

Kuzindikira ndi chithandizo

Mukalumikizana ndi dokotala, mbiri yachipatala ya wodwala imasonkhanitsidwa, kafukufuku amachitika pamfundo ya madandaulo a anthu. Kuyesedwa kwa Laborator ndi njira zothandizira kudziwa matenda amtunduwu ndi komwe.

Kuyesedwa kwa Laborator kumaphatikizapo kuyezetsa magazi konse, kuchuluka kwa shuga mthupi, kuwunika kwa glycosylated hemoglobin, kuyezetsa magazi a biochemical, kuyesa kwa zotupa ndi zomwe zili mu immunoglobulin. Perekani zida zokuthandizani - ma ultrasound am'mimbamo, CT, MRI, kuyesa kwa biopsy, ndi zina zambiri.

Muzochita zachipatala, pakhala pali pomwe matendawa adapangidwira okha popanda kugwiritsa ntchito mankhwala. Komabe, utoto wambiri umafuna chithandizo chokhazikika cha autoimmune pancreatitis.

Odwala amalembedwa zakudya nambala 5. Ndi chitukuko cha matenda ashuga, kutsimikizika kwakukulu ndikudya koyenera osagwiritsa ntchito shuga granured. Conservative therapy imaphatikizapo kugwiritsa ntchito mankhwala otsatirawa:

  • Corticosteroids ndi mafanizo opanga ma hormone a adrenal cortex; kugwiritsa ntchito kwawo kumayeserera njira yochizira. Nthawi yakuvomerezedwa ndi pafupifupi milungu iwiri. Odwala ena amafuna chithandizo chotalikirapo pamlingo wochepa.
  • Immunosuppressants - gulu la mankhwala omwe amalepheretsa chitetezo chambiri. Amalimbikitsidwa ngati kugwiritsa ntchito kwa glucocorticosteroids sikokwanira kapena ngati nkosatheka kuzigwiritsa ntchito.
  • Ma antispasmodics amatha kuyimitsa kupweteka, komwe kumayamba chifukwa chakuchepetsa kwa ma pancreatic ducts.
  • Kukonzekera kwa enzyme kumayendetsedwera kusintha kwa chimbudzi cha chakudya chomwe mumadya.
  • Ngati zowonongeka zam'mimba zilipo, ndiye kuti ma proton pump zoletsa amalembera. Amathandizira kubwezeretsa mawonekedwe a mucous.
  • Insulin yokhala ndi kanthawi kochepa imagwiritsidwa ntchito kuchepetsa matenda a shuga ngati matenda "okoma" apezeka. Nthawi zina mphamvu ya insulin nthawi yayitali imagwiritsidwa ntchito.

Mankhwala othandizira opaleshoni ali ndi makina kubwezeretsa chimbudzi cha ndulu ndi ma ducts a bile. Njira yothandizira ndiyofunikira pokhapokha kuchepa kwapakati pamayendedwe amomwe adapezeka, pomwe palibe zotsatira kuchokera ku glucocorticosteroids.

Kukula kwakanthawi kwamatenda a autoimmune kumachitika chifukwa cha zovuta zomwe zilipo, concomitant autoimmune pathologies ndi kukhalapo / kusowa kwa matenda ashuga. Kupewa kulibe, chifukwa zomwe zimayambitsa kuwonongeka kwa maselo anu sizidziwika ngati mankhwala.

Zomwe zimayambitsa ndi njira zochizira pancreatitis zakambidwa mu kanema munkhaniyi.

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