Mu pachimake kapamba ndi kuchuluka kwa matenda mawonekedwe, inpatient chithandizo ikuchitika, amene mwapadera amafunika opaleshoni kulowererapo. Koma nthawi zambiri, kuti muchepetse kukula kwa kutupa kwa kapamba, kugwiritsa ntchito mankhwala oyenera kumakhala kokwanira.
Chifukwa chake, popewa kukula kwa zovuta, odwala omwe amapezeka ndi kapamba nthawi zambiri amatchulidwa ndi Sandostatin. Malinga ndi pharmacological, mankhwalawa ali pafupi ndi chilengedwe chachilengedwe, chifukwa chomwe chimachepetsa zochitika zachinsinsi za gland.
Mankhwalawa amathandizira minofu ya endocrine, kuthetsa zizindikiro zingapo zopweteka. Kugwiritsa ntchito kwa Sandostatin kumathetsa kufunikira kwa ma analgesic othandizira ena. Zonsezi zimapangitsa kuti ikhale gawo limodzi la mankhwalawa a kapamba.
Makhalidwe a mankhwalawa komanso zotsatira zake
Sandostatin ndi analogue yopanga ya mahomoni somatostatin. Mankhwalawa ali ndi mphamvu yofanana ndi zachilengedwe, koma zotsatira zake zimakhala zazitali.
Mankhwalawa amapezeka ngati jakisoni. Mlingo wake ndi 50, 100 ndi 500 mcg.
Gawo logwira ntchito la Sandostatin ndi octreotide. Monga zowonjezera pazomwe zimapezekera pali mpweya woipa, sodium bicarbonate, madzi a jakisoni, aldit, lactic acid.
Sandostatin chifukwa cha kapamba imakhala ndi zotsatira zingapo zochizira. Chifukwa chake, mankhwalawa ali ndi mphamvu ya antithyroid, amachepetsa kupanga kwa mahomoni STH ndi TSH, omwe amachotsa zizindikiro zowawa za kutupa kwa kapamba.
Komanso, mankhwalawa amachepetsa kuyenda ndi kupanga kwa madzi a m'mimba. Mothandizidwa ndi octreotide, katulutsidwe ka serototin, ma peptides ndi timadzi timene timakula.
Ndi kutupa kwa kapamba, odwala nthawi zambiri amakhala ndi vuto la m'matumbo komanso kuwonda. Kugwiritsa ntchito kwa Sandostatin kumakuthandizani kuti muzolowanso chopondera komanso kulemera. Kuchiza ndi mankhwalawa kumathandizira kuchotsa kutopa konse, komwe nthawi zambiri kumakhudzana ndi chifuwa chachikulu.
Popeza mankhwalawa amachepetsa chinsinsi cha kapamba, nthawi zambiri amakakamizidwa kwa odwala omwe amachitidwa opareshoni. Izi zimakuthandizani kuti muchepetse kupweteka komanso kuti muchepetse chiwonongeko.
Sandostatin nthawi zambiri amalembedwa kwa odwala omwe ali ndi pancreatitis pachimake. Koma nthawi zina, amapatsidwa mtundu wa matenda omwe amakhala ndi kuthekera kwakukulu kuti athetsere zizindikiro zopweteka. Komabe, kuwunika kwa madotolo ndi odwala pankhaniyi ndikosalimbikitsa, chifukwa mankhwalawa ali ndi zotsutsana zingapo komanso zoyipa.
Ndizofunikira kudziwa kuti kuwonjezera pa pancreatitis yovuta, Sandostatin imafotokozedwanso milandu ina:
- kukha magazi;
- acromegaly;
- kupewa mavuto pambuyo ntchito parenchymal England;
- zotupa za kapamba ndi m'mimba thirakiti.
Malangizo ogwiritsira ntchito mankhwalawa
Asanapange chithandizo, tikulimbikitsidwa kupenda magazi ndikupanga ma ultrasound a kapamba ndi m'mimba. Izi zikuwunika mphamvu ya peptide yaulere pa thupi.
Musanagwiritse ntchito, Sandostatin imatsitsidwa ndi mchere kapena madzi a jekeseni. Mankhwalawa amaperekedwa pansi pakhungu kudzera m'mitsempha kapena minyewa katatu patsiku. Koma kwenikweni, mlingo umasankhidwa payekha, kutengera mawonekedwe a thupi la wodwalayo komanso kukula kwa matendawa.
Malangizo ogwiritsira ntchito Sandostatin pancreatitis akuti yankho liyenera kugwiritsidwa ntchito pakati pa chakudya. Ndikofunikira kuti jekeseni lomaliza litengedwe musanagone, zomwe zimachepetsa mwayi wokhala ndi zovuta zina. Kuchiza kumatha kupitilira sabata limodzi mpaka miyezi 2-3.
Kwa odwala omwe akuchitidwa opaleshoni ya pancreatic, Sandostatin amathandizidwa mphindi 60 asanachitidwe opareshoni. Kenako mankhwalawa amapitilira sabata lotsatira ndipo wodwalayo amapatsidwa 0,1 mg wa yankho katatu patsiku pansi pa khungu.
Mukatha kugwiritsa ntchito mankhwalawa, zimayambitsa zovuta, koma nthawi zambiri zimatha mphindi 15 pambuyo pa jakisoni.
Komanso, malangizo a mankhwalawa akuti musanagwiritse ntchito, mankhwalawa amayenera kutenthetsedwa ndi kutentha kwa chipinda, komwe kumapewetsa kupweteka pakukonzekera.
Zotsatira zoyipa, contraindication ndi malangizo apadera
Ngakhale chithandizo chachikulu cha Sandostatin pakugwiritsidwa ntchito, zotsatira zoyipa zingapo zimatha kuoneka. Chifukwa chake, kuchokera mmimba othimbirira, kutulutsa, kupweteka m'mimba, kusanza, kutsegula m'mimba, kusokonezeka kwa ndowe, kunyansidwa komanso kupezeka nthawi zina kumachitika.
Mankhwalawa amatha kukhala ndi vuto lililonse pamtima, lomwe limawonetsedwa ndi arrhythmia, bradycardia ndi tachycardia. Komanso, mankhwalawa amakhudza njira za metabolic, zomwe zimayambitsa kuchepa kwa madzi m'thupi, matenda a anorexia komanso kusinthasintha kwa shuga m'magazi.
Ponena za dongosolo la endocrine, octreotide imatha kubweretsa vuto la chithokomiro komanso hypothyroidism. Matenda wamba amaphatikizapo kuwawa pakakonzedwe ka mankhwalawa komanso kusapeza bwino m'malo a jekeseni.
Zotsatira zina zoyipa zomwe zimachitika mutagwiritsa ntchito Sandostatin:
- Chiwindi - kuwonjezeka kwa kuchuluka kwa bilirubin m'magazi, cholecystitis, matenda a ndulu.
- Dermatological matenda - kuyabwa, matupi awo sagwirizana, zotupa.
- Machitidwe amsempha - migraines, chizungulire, kukomoka.
Pali zingapo zotsutsana zomwe zimaletsa kugwiritsa ntchito mawonekedwe ena a somatostatin. Mwapadera, mankhwalawa sangathe kugwiritsidwa ntchito mwachidwi pazinthu zake.
Otsutsa contraindication ndi shuga, cholelithiasis, pakati ndi mkaka wa m`mawere. Kodi ndizotheka kupatsa ana a Sandostatin? Zomwe amamuchitira mwana ndi mankhwala ndizochepa, chifukwa chake pazoyenera kugwiritsa ntchito kwake ziyenera kupangidwa ndi adokotala.
Ponena za kutenga pakati komanso kuyamwa, Sandostatin imagwiritsidwa ntchito pangozi. Kupatula apo, maphunziro omwe akuwonetsa kuchuluka komwe kumayamwa mkaka ndi placenta sikunachitike.
Zolemba zina za mankhwalawa:
- Pochiza odwala okalamba, palibe chifukwa chochepetsera mulingo.
- Popeza chizungulire chimakonda kuchitika pambuyo popereka mankhwala munthawi ya chithandizo, muyenera kusamala mukamayendetsa galimoto ndikuchita ntchito yomwe imafunika kuchitapo kanthu mwachangu.
- Octreotide imaletsa mayamwidwe a cimetidine ndi cyclosporin.
- Kuti muchepetse zovuta zomwe zingayambitse kugaya zakudya, ndibwino kuperekera mankhwalawa musanayambe kugona kapena pakati pa chakudya.
- Ndi insellitus wodwala yemwe amadalira insulin panthawi yamankhwala ndi Sandostatin, kufunika kwa insulin kumachepa.
Pogwiritsa ntchito molakwika mankhwalawa, mankhwala osokoneza bongo amatha kuchitika.
Vutoli limadziwika ndi matenda otsegula m'mimba, kusokonezeka kwa kupangika kwa mtima, kukhumudwa pamimba, kutulutsa nkhope, nseru, ndi chopondapo.
Mtengo, analogi, ndemanga
Mankhwala atha kugulidwa ku malo ogulitsira mankhwala pokhapokha ngati pali mankhwala omwe dokotala amakupatsani. Mtengo wake umachokera ku 1800 mpaka 3000 rubles.
Zofananira zotchuka kwambiri ku Sandostatin ndi Octreotide, Okeron, Genfastat, Octra, Octrade, Octretex, Ukreotide, Seraxtal, Okreastatin ndi ena. Palibe mwachindunji mankhwala a mapiritsi.
Ndemanga za odwala omwe ali ndi vuto la kapamba za Sandostatin ndi zabwino. Mankhwalawa amathandizanso kupweteka mofulumira ndi kutupa kwa kapamba. Komabe, imakhudza chiwindi, ndipo mtengo wake umakhala wokwera kwambiri. Chifukwa chake, mankhwalawa amaperekedwa pokhapokha pokhapokha pokhapokha.
Pankhani ya mankhwalawa Sandostatin akufotokozedwa mu kanema m'nkhaniyi.
