Ndi kuchuluka kwa lipoprotein otsika kwambiri, ndikofunikira kuchitapo kanthu pofuna kutsitsa mtengo. Pali mitundu yambiri yamankhwala yomwe imakhudza bwino kagayidwe ka mafuta ndikuletsa mapangidwe a LDL.
Kuti muchepetse cholesterol, mankhwala amaikidwa omwe ali m'gulu la ma statins kapena ma fiber. Ndalama zatsimikiziridwa pazaka zambiri. Amalembedwa panthawi yomwe njira zina zochiritsira - chakudya chathanzi, zolimbitsa thupi, kuchepa thupi, ndi zina zambiri, sizinapatse zotsatira zomwe mukufuna.
Mankhwala ambiri amatha kugulidwa ku pharmacy popanda mankhwala a dokotala. Koma izi sizitanthauza kuti wodwala matenda ashuga amatha kudzilingalira. Kuti mukwaniritse zochizira, mathandizidwe amomwemo kuti mugwiritse ntchito mankhwala amafunikira.
Ganizirani mapiritsi amomwe amachepetsa cholesterol m'thupi ndi abwino, momwe angamwere bwino, ndipo ndi zovuta ziti zomwe zingachitike odwala omwe ali ndi matenda ashuga?
Mfundo yopangira ma statins
Mapiritsi a cholesterol a gulu la statin ndi omwe amapatsidwa nthawi zambiri. Mankhwala amathandizira kuchepetsa kuchuluka kwa lipoproteins otsika m'thupi, kuchepetsa kupezeka kwa LDL m'chiwindi cha wodwalayo. Ziwerengero zikuwonetsa kuti OH (cholesterol yathunthu) imatsika ndi 30-45% kuchokera pamlingo woyamba, komanso kuchuluka kwa zinthu zoyipa ndi 40-60%.
Chifukwa cha kugwiritsidwa ntchito kwa ma statins, ma lipoproteins okwera amatha kuchulukitsidwa, ndipo mwayi wopanga zovuta za ischemic mu matenda ashuga umatsitsidwanso ndi 15%. Ma Statin samapereka mutagenic ndi carcinogenic zotsatira, zomwe ndizotsimikizika kuphatikiza.
Kudzichiritsa nokha pa mapulani oterowo nkoletsedwa. Popeza kuwunika kokwanira kwa wodwalayo kumafunikira kuti athe kuwunika onse owopsa ake. Mukamapereka mankhwala, dziwani izi:
- Kukhalapo / kusakhalapo kwa zizolowezi zoyipa;
- Okwatirana
- Gulu la odwala;
- Matenda oyamba (matenda oopsa, matenda a shuga, ndi zina).
Ngati mungafune mankhwala kuchokera ku ma statins, mwachitsanzo, Atorvastatin, Simvastatin, Zokor, Rosuvastatin, ndiye ayenera kutengedwa pa mlingo womwe woyesedwa ndi katswiri wa zamankhwala amapanga. Mankhwala, kuyezetsa magazi kwamomwe amadziwika nthawi ndi nthawi kuyang'anira zizindikiro.
Mapiritsi ochepetsa cholesterol yamagazi siotsika mtengo. Ngati wodwalayo sangathe kugula mankhwala aliwonse, ndiye kuti sikulimbikitsidwa kuti azisankha yekha analogue. Tiyenera kufunsa adotolo kuti apereke njira ina yomwe ingagwirizane ndi mtengo wa odwala matenda ashuga. Chowonadi ndi chakuti zamagetsi opanga zoweta ndizoperewera kwambiri pamakhalidwe ndi ochiritsira osati mankhwala oyamba okha, komanso ma generics opanga akunja.
Chithandizo chikamalembera okalamba, kuyanjana ndi mankhwala ochizira matenda am'mimba, matenda oopsa, ndi matenda oopsa a shuga kuyenera kukumbukiridwa. Panthawi imeneyi, odwala ali ndi chiopsezo chowirikiza cha myopathy.
Statin tikulimbikitsidwa kuganizira izi:
- Pamaso pa matenda amchiwindi osakanikirana, ndibwino kumwa Rosuvastatin, koma osachepera mlingo, womwe umapereka zomwe mukufuna. Kugwiritsa ntchito kwa mankhwala a Pravaxol ndikololedwa. Mankhwalawa alibe zotsatira zoyipa ku chiwindi, koma samaphatikizidwa ndi mowa komanso antibacterial.
- Ngati wodwala matenda ashuga apweteka pafupipafupi, kapena pali kuwonongeka kwawo, ndibwino kugwiritsa ntchito Pravastatin. Mankhwalawa alibe poizoni m'misempha ya wodwalayo, motero, chiopsezo chokhala ndi myopathy ndi matenda a shuga chimachepa.
- Ngati wodwala akudwala matenda a impso, ndiye kuti simuyenera kumwa fluvastatin. Kwambiri zikutsimikizira zovuta za mankhwalawa pazomwe zimagwira impso.
Kuphatikizidwa kwa mitundu ingapo yama statins ndikuloledwa, mwachitsanzo, Atorvastatin + Rosolipt.
Sizowoneka bwino kuphatikiza ma statins ndi nicotinic acid. Zimatha kupangitsa kugwa kwamphamvu mu shuga m'magazi a anthu odwala matenda ashuga, zomwe zimapangitsa kuti magazi azituluka m'mimba.
Statins: mndandanda wa mankhwala ndi mawonekedwe ogwiritsira ntchito
Ma Statin amatchulidwa nthawi zambiri. Amathandizanso kuchepetsa kuchuluka kwa cholesterol m'magazi a odwala. Kugwiritsa ntchito kwawo motsutsana ndi matenda ashuga kuli koyenera, komabe, zoopsa zonse mu chithunzi china ziyenera kukumbukiridwa. Kutsitsa cholesterol kumachitika chifukwa choletsa mapangidwe ake m'chiwindi.
Statin adayikidwa m'mibadwo. Pali anayi a iwo. Ali ndi zinthu zosiyanasiyana zogwira, mosiyanasiyana mu contraindication, mavuto. M'badwo woyamba umaphatikizapo waukulu yogwira pophika simvastatin. Amakhulupirira kuti mankhwala am'badwo uno amaphunziridwa kwambiri, koma samalimbikitsidwa, popeza mapiritsi amphamvu kwambiri adawonekera.
Mapiritsi satchulidwa konse ngati wodwala matenda ashuga ali ndi mbiri ya myopathy kapena ali pachiwopsezo chachikulu chotenga matendawa. Sayenera kumwedwa pakamwa, ndi kuyamwitsa, pakuchulukana kwa matenda a chiwindi.
M'badwo woyamba wama statin umaimiridwa ndi mankhwala otsatirawa:
- Simvor;
- Simvastatin;
- Vasilip;
- Ariescore et al.
Mankhwala amawoneka ngati ma analogues. Ngakhale mayina osiyanasiyana, ali ndi mfundo imodzi yochitapo kanthu. Mlingo amasankhidwa payekha. Koma mwezi woyamba wa maphunziro achire umaphatikizapo kugwiritsa ntchito 10 mg patsiku. Ngati ndi kotheka, mlingo umakulitsidwa.
Mankhwala a m'badwo wachiwiri amaphatikizanso yogwira fluvastatin. Mwa gulu ili, Leskol Forte nthawi zambiri amalimbikitsidwa. Zotsatira zabwino za mankhwalawa zimawonedwa mu matenda a shuga, chifukwa mapiritsi amachotsa urea mthupi. Kuti mukwaniritse zomwe mukufuna, muyenera kudya.
Mbadwo wachitatu:
- Atomax
- Tulip.
- Anvistat.
Gawo lomwe limagwiritsa ntchito mankhwalawa ndi atorvastatin. Zimathandizira kuchepetsa ndende ya otsika osalimba lipoproteins. Malangizowo akuti mapiritsi amatengedwa kamodzi patsiku, kuyambira pa 10 mg. Mlingo wapamwamba tsiku lililonse ndi 80 mg. Kuchepetsa kwambiri cholesterol, ma statin amatha kuphatikizidwa ndi mankhwala ena, mwachitsanzo, Omacor.
M'badwo wachinayi (wotsiriza) - mankhwala otetezeka kusintha mawonekedwe a cholesterol. Izi zikuphatikizapo Rosart, Rosuvastatin, Krestor. Dziwani kuti ambiri akufuna mankhwala a Novostatin, koma mankhwalawa sapezeka. Itha kuganiziridwa kuti kusaka ndikulinga ku Lovastatin.
Thupi rosuvastatin limaphatikizidwa chifukwa cha tsankho lactose, kuperewera kwa lactase, hypothyroidism, hypersensitivity, kwambiri pathologies mu gawo la kubwezeretsa.
Zimapangira kuti muchepetse mafuta m'thupi
Fibates ndi gulu lopatula la mankhwala omwe amachepetsa chidwi cha LDL chifukwa chosintha kapangidwe ka lipid. Nthawi zina, zimaphatikizidwa ndi ma statins kuti muchepetse kuthana ndi mavuto, koma izi sizothandiza.
Filates sinafotokozedwe kwa odwala matenda ashuga ngati ali ndi mbiri yolephera kuyenda bwino kwa chiwindi, matenda owopsa a chiwindi, kuperewera kwaimpso, kapena matenda enaake. Simungathe kumwa mankhwalawa panthawi yapakati, ndikuyamwitsa, hypersensitivity.
Mankhwala ndi omwe anapangidwa, ali ndi zovuta zambiri, motero kugwiritsa ntchito kumayambira ndi mlingo wochepa. Pang'onopang'ono zimawonjezeka pakapita mwezi umodzi. Kuphatikiza apo, mutha kugwiritsa ntchito wowerengeka azitsamba, mwachitsanzo, msuzi wa adyo uli ndi mphamvu yoyeretsa mitsempha yamagazi ndikuyeretsa zolembera za cholesterol.
Oimira gulu la fibrate:
- Gemfibrozil - mapiritsi a cholesterol ndiabwino kwambiri, koma osati otsika mtengo. Mtengo ndi ma ruble 1700-2000 phukusi lililonse. The ntchito limapereka kuchepa ndende ya triglycerides, kuchepa kupanga lipids, amene imathandizira kuchotsedwa kwa zoipa mafuta m'thupi. Mutha kugula ku pharmacy kapena kugula pa intaneti;
- Bezafibrat ndi mankhwala omwe amathandiza kuyeretsa magazi m'magazi a cholesterol. Itha kuthandizidwa kwa odwala matenda ashuga omwe ali ndi mbiri yamatenda am'mtima komanso angina pectoris. Mtengo kuchokera ku ruble 3000 pa paketi iliyonse.
Etofibrate amachepetsa cholesterol yamagazi, amachepetsa mamasukidwe amwazi, amadziwika ndi katundu wa antithrombotic. Tengani 500 mg mukatha kudya. Poyerekeza ndi chithandizo cha nthawi yayitali, kuwongolera ndulu kumafunika.
Zotsatira zoyipa za ma statins ndi ma fiber
Ma tebulo azachipatala amabweretsa mavuto ambiri omwe ali chifukwa chogwiritsa ntchito ma statins. Mankhwala a gululi nthawi zambiri amabweretsa kusokonezeka kwa kugona, asthenic syndrome, kupweteka mutu, nseru, kudzimbidwa / kutsekula m'mimba, kupweteka kwam'mimba, myalgia, kuwonjezeka / kuchepa kwa kuthamanga kwa magazi.
Kuchokera kumbali ya mavuto amkati mwazinthu zamkati ndikuwonetsetsa komanso kukumbukira zimawonekera, pali chiwopsezo chachikulu, chizungulire. Matenda a shuga a polyneuropathy amatha. Kuchokera pagawo logaya - hepatitis, kuchepa msanga kwa thupi, cholestatic jaundice, pancreatitis pachimake - kutupa kwa kapamba.
Malinga ndi malangizo a mankhwalawa, kupezeka kwa thrombocytopenia, matenda a shuga. Matenda onse amakhudzidwa. Mawonetsedwe ake akuphatikizapo zotupa pakhungu, urticaria, kuyabwa ndi kuwotcha khungu, hyperemia, erythema yapamwamba.
Poyerekeza ndi ma statins, ma fibrate amaloledwa bwino ndi odwala matenda ashuga, ndipo zochitika zovuta sizimakhalapo. Izi zikuphatikiza:
- Chizungulire
- Mutu.
- Kusokonezeka tulo.
- Leukopenia
- Anemia.
- Alopecia mwa amuna.
- Ziwengo
Ndikupanga zotsatira zoyipa, kukonza mankhwalawa ndikofunikira - kuchepetsa mlingo wa mankhwalawa kapena kuphatikiza mankhwala angapo.
Mankhwala ena otsitsa cholesterol
Pali kutsutsanabe pakufunika kwa Aspirin kuchokera ku cholesterol yayikulu - akatswiri azachipatala sangathe kudzagwirizana. Ena amaganiza kuti ndi mankhwala otsika mtengo, pafupifupi panacea, amalimbikitsa kutenga nthawi yayitali ngati kupewa atherosclerosis ndi matenda osiyanasiyana amtima.
Madokotala ena samapereka mankhwala, ngakhale mopitilira, amayesa kuletsa mankhwalawa. Palibe mgwirizano. Koma maphunziro azachipatala amawonetsa kuti mapiritsiwa ndi otsika kwambiri, chifukwa chake odwala matenda ashuga amakhala bwino osamamwa, mochepera okha.
Kuchepetsa cholesterol m'thupi kumafuna njira yolumikizidwa, kotero ma statins ndi ma fiber amatha kuphatikizidwa ndi mankhwala ena.
Chithandizo cha hypercholesterolemia chimaphatikizapo mankhwala:
- Probucol ndi mankhwala a hypolipidemic komanso antioxidant omwe amathandizira kutsimikiza kwa LDL mu shuga. Imalepheretsa kupanga cholesterol mthupi la munthu, imathandizira kuchotsedwa kwa zinthu zoyipa m'magazi. Kugwiritsidwa ntchito ndi maphunziro kwa nthawi yayitali;
- Alisat ndi mankhwala otsika mtengo komanso othandiza omwe ali ndi zochita zambiri. Imayendetsa kuthamanga kwa magazi, imachepetsa mamasukidwe amwazi, imasungunuka magazi ndikuyetsa ma cholesterol plaque. Mapiritsiwo amakhala ndi adyo, ndiye si mankhwala athunthu.
Ndi hypercholesterolemia, mapiritsi amayikidwa kokha ndi dokotala, poganizira kuchuluka koyambirira kwa LDL komanso mkhalidwe wa wodwalayo. Chithandizo cha anthu odwala matenda ashuga chimayendera limodzi ndi zakudya zopatsa thanzi komanso zolimbitsa thupi, zomwe zimakuthandizani kuti mulibe matenda a cholesterol.
About mankhwala ochepetsa cholesterol akufotokozedwa mu kanema m'nkhaniyi.
