Kukonzekera zochizira matenda a arteriosulinosis

Chimodzi mwazinthu zovuta zomwe zimachitika chifukwa cha matenda ashuga ndi matenda amiseche. Matendawa amatengedwa kuti ndi omwe akuwatsogolera kulumala komanso kufa kwa anthu.

Ndi discepulatory encephalopathy, minyewa yam'mimba yotupa, yomwe imakhudza thanzi la minofu yaubongo ndipo imathandizira kuwoneka kwa atherosranceotic stenosis. Zotsirizirazi nthawi zambiri zimayambitsa matenda a ischemic komanso kuchepa kwa mitsempha.

Popeza matendawa amakhala ndi zovuta zambiri m'matenda a shuga, mankhwalawa matenda am'madzi amtundu wa mankhwala ayenera kukhala ovomerezeka. Koma musanayambe kugwiritsa ntchito mankhwala osokoneza bongo, muyenera kumvetsetsa zomwe zimayambitsa, zizindikiro za matendawa ndikufunsani dokotala.

Zolemba za matendawa

Atherosclerosis ndi matenda a mitsempha yayikulu, yomwe imadziwika ndi kudzikundikira kwa lipids pamakoma amitsempha yamagazi komanso kukula kwa minyewa yolumikizira ma cell. Chomwe chimayambitsa matendawa ndikulephera kwama metabolism amafuta. Zinthu zakunja ndi zamkati zimatha kutsogolera matendawa.

Zifukwa zomwezo zimaphatikizana ndi ukalamba, pomwe machitidwe ndi ziwalo zimayamba kugwira ntchito zoyipa kwambiri chifukwa cha ukalamba. Gender imathandizanso kwambiri pakupezeka kwa matenda a ubongo. Chifukwa chake, mwa amuna, matendawa amawonekera kawirikawiri motsutsana ndi maziko a kuchepa kwa estrogen, omwe akuphatikizidwa ndi kuphwanya kwa triglycerides.

Kubadwa kwamtunduwu kumatanthauzanso zinthu zosasinthika pakuwonekera kwa zolembedwa zamtundu wa atherosrance? Zoyipa zomwe zimayambitsa chitukuko cha matendawa ndi monga:

1. kupsinjika
2. uchidakwa, kusuta fodya;
3. hypercholesterolemia;
4. kagayidwe kachakudya matenda;
5. kuthamanga kwa magazi;
6. aakulu hyperglycemia;
7. kuperewera kwa zakudya m'thupi;
8. kunenepa kwambiri;
9. kuchuluka kwa homocysteine ​​m'magazi;
10. kulephera kwa aimpso.

Matenda enanso amakula motsutsana ndi maziko a kuchepa kwa thupi, hyperfibrinogenemia. Ndizosangalatsa kuti, kutengera zomwe zachitika, mitundu ya atherosulinosis imasiyanitsidwa ndi metabolic, zaka, poizoni, matupi awo komanso matendawa (syphilis, chifuwa chachikulu).

Ngati matendawa akuwoneka motsutsana ndi ochepa matenda oopsa, ndiye kuti amatchedwa hyalinosis. Matendawa akapezeka chifukwa cha kuchuluka kwa mchere wa calcium m'mitsempha, ndiye kuti wodwalayo amapezeka ndi mediacalcinosis.

Pali magawo anayi a chitukuko cha matenda amiseche. Pa gawo loyamba, lipid amawoneka mawonekedwe, ndipo chachiwiri - zolembera zam'mimba.

Gawo lachitatu limadziwika ndi mapangidwe a atherosselotic zolembera komanso kudzikundikira kwa ma thrombotic misa. Pa gawo lotsiriza la matendawa, atherocalcinosis imachitika, momwe mumakhala kulowetsedwa kwa mapangidwe ndi kusintha kwa mitsempha.

Kumayambiriro kwa chitukuko, atherosulinosis sikuwonetsedwa. Odwala nthawi zina amangodandaula za kutopa kwambiri, kusasunthika bwino, kupweteka mutu.

Pamene matenda akupita patsogolo, zizindikiro zotsatirazi zimachitika:

• tinnitus;
• Chizungulire
• kudumpha mu kuthamanga kwa magazi;
• mantha
• kusowa tulo
• kusokonezeka kwa kukumbukira;
• kusasamala ndikuyenda kwa manja;
• zolakwika mu ntchito zowoneka ndi zolankhula.

Muzochitika zapamwamba, pali ziwalo za thupi zodziwikiratu, kupuma kwa nkhope, dzanzi la miyendo. Komanso, atherosclerosis ya siteji ya 3-4 imadziwika ndi chizindikiro monga kukhumudwa. Nthawi zambiri, odwala amadandaula chifukwa chosowa pogwira, ndipo mwa odwala ena, kusokonekera pang'ono kwamunthu kumachitika.

Musanagwiritse ntchito mankhwala aliwonse a matenda a chithokomiro, muyenera kudziwa bwino za vutoli. Kafukufuku wa Laborator akuphatikizapo kuyezetsa magazi ndi ma biochemical.

Njira yothandiza kwambiri yopezera matenda a atherosulinosis ndi MRI. Ultrasound, angiography ndi transcranial dopplerography imathandizanso chimodzimodzi.

Mfundo zachikhalidwe zamankhwala

Chithandizo cha matenda amtundu wa arteryosulinosis ziyenera kukhala zokwanira komanso zogwirizana ndi njira zowonetsera, pathogenetic komanso kukonza. Koma asanamwe mankhwala, madokotala amalangiza odwala kuti ayang'anenso zakudya zawo.

Mankhwala othandizira pakudya amachititsa kuti mankhwalawa azigwira bwino ntchito ndipo amachepetsa kukula kwa matendawo. Mfundo yayikulu yokhudza zakudya m'zakudya za m'magazi ndi kukana zakudya zamafuta zomwe nyama zimachokera, kugwiritsa ntchito mchere pang'ono komanso zakudya zilizonse zovulaza (chakudya chofulumira, masoseji, zokhwasula-khwasula).

Ndi mtima pathologies, madokotala amalimbikitsa kuyang'anira kuthamanga kwa magazi, kuyang'anira shuga ndi mafuta m'thupi m'magazi. Chofunikanso kwambiri ndikukana kukakamira, kuchuluka kwa kulemera, zochitika za tsiku ndi tsiku. Tisaiwale za zolimbitsa thupi zolimbitsa thupi komanso kupewa mavuto.

Ngati atherosulinosis ya mitsempha ya chithokomiro yapezeka, chithandizo cha mankhwala chimakupatsani zotsatirazi:

1. kuthamanga kwa magazi;
2. utachepa hypoxia;
3. matenda a lipid kagayidwe;
4. kukonzanso kwa lumen ya mtima.

Chithandizo cha matenda a chithokomiro cha ubongo chimaphatikizapo kugwiritsa ntchito mankhwala omwe ali m'magulu osiyanasiyana a mankhwala.

Statins, bile acid sequestrants, antiplatelet agents, Vitamini PP, ma fibrate, mankhwala a anticholesterol ndi mankhwala omwe amaonjezera kuthamanga kwa magazi amagwiritsidwa ntchito.

Madera

Mankhwalawa amawerengedwa ngati maziko othandizira atherosulinosis, chifukwa amachotsa chifukwa cha mawonekedwe ake - hypercholesterolemia.

Kuchepetsa mphamvu ya ma statins ndiko kuletsa kubisalira kwa enzyme yophika yomwe imayambitsa kupanga cholesterol, kuonjezera kuchuluka kwa "zofunikira" zamtali wa lipoproteins, kusintha matenda a lipid, kupuma kwa maselo a cell, komanso kulimbitsa ndi kulimbitsa magazi.

Mapiritsi abwino kwambiri a mitsempha ya m'magazi kuchokera ku gulu la zigawo zatsopano za mibadwo:

Ngakhale kuti ma statins ali ndi mphamvu yokhala ndi lipid yotsitsa, ali ndi zovuta zingapo. Ambiri mwa iwo ndi minofu minofu pathologies, thupi lawo siligwirizana, kusagwira ntchito kwa chapakati mantha dongosolo ndi opuwala magawo a dongosolo.

Contraindication kutenga ma statins - matenda a chiwindi, ana osakwana zaka 8, munthu asalole.

Mankhwala amaletsedwa kugwiritsa ntchito ngati muli ndi pakati, mkaka wa m'mawere ndi mawonekedwe okwanira a transaminases m'magazi.

Fibates

Fibroic acid amachokera ku gulu lachiwiri lothandiza kwambiri la mankhwala okhala ndi matenda a lipid. Amachepetsa kuchuluka kwamafuta m'thupi ndi 50%, kumawonjezera zofunikira za cholesterol m'magazi. The achire zotsatira zimatheka mwa kuwonjezera kuchuluka kwa michere yapadera yomwe imayambitsa kuchotsedwa kwa otsika osalimba a lipoprotein kuchokera mthupi kudzera mu ndulu.

Mu malo a atherosulinotic, ma fibrate amadziwika ndi ma statins, makamaka pamene hypercholesterolemia imayendera limodzi ndi triglyceridemia. Koma ndi kulekerera kwa michere ya enzyme ya chiwindi, zotumphukira za michere zimatha kutengedwa padera.

Chithandizo chothandiza cha matenda a m'magazi a arteryosulinosis kuchokera ku gulu la fiber ndi Fenofibrate. Mlingo wa tsiku ndi tsiku wa mankhwalawa ukhoza kuchokera ku 140 mpaka 400 mg.

Zothandiza kuchokera ku fibroic acid, ngati ma statins, amatengedwa mu maphunziro - kuyambira miyezi itatu. Mapiritsi aledzera mpaka 2 pa tsiku.

Mankhwala otchuka kuchokera ku kalasi la fibrate:

• Bezafibrat. Mutha kutenga mpaka 0,3 ga malonda nthawi.
• Clofibrate. Imakhala ndi zochitika mwatsatanetsatane - imatseka enzyme ya chiwindi, imaphwanya mafuta, imachepetsa kukhudzika kwa magazi ndi ndende ya uric acid. Mutha kumwa mpaka mapiritsi 9 patsiku, mapiritsi atatu atatu nthawi imodzi.
• Gemfibrozil. Mankhwala amatengedwa 1 (900 mg) kapena 2 (600 mg) kamodzi patsiku musanadye.
• Lipanor Mlingo m'masiku 90 oyambirira a chithandizo ndi 100 mg patsiku, ndiye kuti ukhoza kuwonjezeka mpaka 200 mg. Ngati ndi kotheka, mankhwalawa amagwiritsidwa ntchito zaka zingapo.
• Waprofibrate. Amasiyana ndi ma fiber ena pakapita nthawi yayitali, zomwe zimachepetsa nthawi yayitali ya chithandizo komanso kuchuluka kwa Mlingo wa mankhwalawa. Masabata oyamba a 8-12, mankhwalawa amaperekedwa mu mawonekedwe a monotherapy, ndiye kuti kugwiritsidwa ntchito kwake kumaphatikizidwa ndi mankhwala ena a anti-atherosselotic.

Ndemanga ya anthu ambiri omwe ali ndi matenda atherosulinosis amatsimikizira kuti mu 90% ya milandu, ma fibrate amaloledwa bwino. Chifukwa chake, zovuta zoyipa (chifuwa, nseru, kugaya chakudya, kuwonongeka kwa potency) ndizosowa kwambiri. Komabe, pankhani ya mgwirizano wa fibroic acid wokhala ndi ma statins, ntchito ya chiwindi imakonda kuipiraipira.

Aliyense fibrate contraindicated mu aimpso kapena kwa chiwindi kusakwanira, pakati ndi mkaka wa m`mawere.

Mankhwalawa satchulidwa chifukwa cha majini omwe amapezeka mu carbohydrate metabolism, ndipo ana ndi achinyamata amaletsanso kumwa.

Ma antiplatelet othandizira komanso othandizira ena

Ma antiplatelet othandizira omwe amachepetsa kulumikizana kwa ma enzyme oumbidwa, omwe amachititsa kuti magazi azituluka komanso kupewa kuphatikizana kwa magazi. Mankhwala odziwika kwambiri omwe ali mgululi ndi Aspirin.

Ubwino wa mankhwalawa ndi wotsika mtengo komanso kuchitapo kanthu mwachangu. Komabe, muyenera kudziwa kuti asidi acetylsalicylic amakwiyitsa mucosa wam'mimba, chifukwa chake amatsutsana mu gastritis ndi zilonda zam'mimba.

Zida zina zodziwika bwino za antiplatelet, kugwiritsa ntchito nthawi zonse komwe kumathandizira kupewa kulowererapo kwa thrombosis, ndi Thrombo ACC, Cardiomagnyl, Clopidogrel.

Bile acid sequestrants ndi gulu lina la mankhwala lomwe limapangidwira matenda amisempha. Othandizawo amachita mogwirizana ndi mfundo yapadera ya kusinthanitsa kwa ma ion. Mankhwala amachotsa mafuta achilengedwe m'thupi, kuphatikiza cholesterol yoyipa.

Poyerekeza ndi mankhwalawa omwe ali pamwambapa, ogwiritsira ntchito mankhwala omwe ali ndi pakati amakhala ndi mphamvu yokwanira yaukatswiri. Koma ali ndi maubwino - mtengo wovomerezeka komanso chiwopsezo chochepa chodana ndi zovuta.

Otsatira otchuka:

1. Mtundu. Kuyimitsidwa akutengedwa pakamwa Mlingo wa 4 ga nthawi pamaso chakudya. Kutalika kwa mankhwala kumatsimikiziridwa ndi adokotala. Zotsatira zoyipa zoyipa ndiz kuphwanya chimbudzi, kuchepa kwa kuchuluka kwamavitamini osungunuka m'thupi.
2. Colestipol kapena Colestid. Amapezeka mu mapiritsi (5 g) ndi ufa (1 g). Pa gawo loyambirira la chithandizo, kumwa kamodzi kwa mankhwalawa ndi magalamu 5, kenako, kuchuluka kwake kumatha kuwonjezeka mpaka 30 g.
3. Questran imapezeka mu ufa. Mlingo wa tsiku ndi tsiku wa ana ndi 1 sachet, kwa akulu - 6 amiseche. Pa mankhwala ndi mankhwalawa, tikulimbikitsidwa kumwa madzi ambiri.

Mankhwala ena othandiza

Vitamini PP imagwira ntchito yofunika kwambiri pothandizira matenda a atherosulinosis. Katunduyo ali ndi zinthu zingapo zabwino. Ili ndi hypotensive, anticholesterol, vasodilator ndi fibrinolytic.

Niacin mu ubongo wa arteriosulinosis imayambitsa lipoproteidlipases ndikuchotsa mafuta aulere acid, kuchepetsa ndende ya TG.

Zinthu zopangidwa ndi Vitamini PP zimapezeka m'mitundu mitundu ndipo zimatengedwa mukatha kudya. Mlingo watsiku ndi tsiku womwe ndi theka magalamu.

Mankhwala osokoneza bongo a nicotinic acid amatha kuyambitsa kutentha. Contraindication - urolithiasis, chiwindi kulephera, kugwira ntchito bwino kwa kugaya chakudya.

Komanso, ndi atherosulinosis, vasodilators ndi mankhwala. Amakulitsa kuunikira kwa mitsempha yaubongo ndikuwongolera njira ya matendawa, omwe amasintha kayendedwe ka magazi ndikuwonjezera mphamvu ya neural metabolism.

Mankhwala ogwira vasodilator:

• Cinnarizine;
• Norvask
• Nimodipine;
• Lacipil;
• Adalat ndi ena.

Payokha, ndikofunikira kuzindikira mankhwala omwe amatchedwa Detralex. Awa ndi mankhwala atsopano omwe amatsuka mwachangu ndikuwongolera mitsempha yamagazi muubongo. Koma nthawi zambiri, Detralex imathandizidwa kuti ichotsetse matenda a atherosulinosis, chifukwa amachotsa kutupa, kulemera ndi kupweteka m'miyendo.

Mavitamini ndi mchere ndi gawo limodzi lofunikira la zovuta kuchitira kuti magazi atulutse mitsempha ndi cholesterol plaque. Zinthu zofunikira zama cell pathological: mavitamini PP, C, B ndi kufufuza zinthu - silicon, potaziyamu, selenium.

Popeza atherosulinosis nthawi zambiri imayendera limodzi ndi matenda oopsa, mankhwala opatsirana a hypotensive amaphatikizidwa ndi zovuta kuchitira odwala matenda ashuga. Indapamide, Captopril, Hydrochlorothiazide, Nifedipine ndi Carvedilol ali ndi chithandizo chabwino. Ndipo pamlingo wapamwamba kwambiri wa atherosulinosis, wodwala amatha kupatsidwa ma dontho omwe ali ndi mankhwala amphamvu kuti ayeretse magazi ndi kuwonda.

Kuti muthane ndi zosasangalatsa za ma pathological a mtima, chithandizo chamankhwala chimachitika. Nthawi zambiri, dokotala amalembera antidepressants, psychotropic mankhwala, analgesics, tranquilizer.

Monga adjunct mankhwala omwe ali ndi chiopsezo chowonjezeka chamagazi, mafuta onunkhira ozikidwa pazomera zamankhwala angagwiritsidwe ntchito. Ndipo ngati angafune, odwala amatha kuwonjezera chithandizo chokwanira ndi wowerengeka azitsamba.

Ndi atherosclerosis yaubongo, zitsamba monga periwinkle, mankhwala a mandimu, valerian, katsabola, timbewu, borax, melilot, meadowsweet, chithandizo cha clover. Pofuna kukopa kwa microcirculation, kuchotsa kwa kuphipha kwamankhwala ndi kuphipha magazi, makonzedwe okhala ndi ginko-biloba yotulutsa -Tanakan, Ginko Fort ndi Bilobil amagwiritsidwa ntchito.

Momwe ma atherosclerosis amathandizira akufotokozedwa mu kanema munkhaniyi.