Mankhwala ochepetsa mphamvu ya cholesterol amadziwika kuti ndi mankhwala ozizwitsa a zana lino. Odwala omwe ali ndi cholesterol yochepa kwambiri nthawi zambiri amalimbikitsidwa ndi madokotala kuti ayambe kumwa mankhwala a statin.
Kodi ma statins ndi ati? Mankhwalawa ndi mankhwala omwe amalembedwa kuti achepetse cholesterol. Statins imagwira ntchito poletsa enzyme yofunikira popanga cholesterol m'chiwindi. Popanda thandizo la enzyme imeneyi, thupi silingasinthe mafuta owonongedwa kukhala cholesterol.
Kuchulukana kwa cholesterol komwe kumazungulira m'mitsempha kumakhala koopsa chifukwa cholesterol imakonda kudziunjikira khoma lamankhwala ndikupanga mapangidwe a atherosranceotic cholesterol plaques, omwe amachepetsa kwambiri ngozi zamatenda am'mtima - stroko komanso mtima.
Pali mitundu ingapo ya mankhwala. Mulinso ma statins amphamvu:
- Atorvastatin;
- Rosuvastatin;
- ma statins apakatikati mwamphamvu, omwe Simvastatin ndi woimira.
Odwala ambiri amatenga mankhwalawa, poganiza kuti mwanjira imeneyi amaletsa kapena kuchedwetsa kukula kwa atherosulinosis. Palinso umboni wabodza wamadzi akumwa olemera.
Palibe kukayikira kuti ma statins amatha kutsitsa cholesterol mwachangu, koma funso ndikuti kodi odwala onse ayenera kuwagwiritsa ntchito, atapatsidwa zovuta zoyipa za mankhwalawa.
Kuphatikiza apo, zidapezeka kuti ngakhale ma statins ali ndi cholesterol yotsika kwambiri mwa anthu omwe ali ndi matenda amtima, zotsatira zake ndizochepa kwambiri kotero sizitanthauza zifukwa zoyipa zomwe mankhwalawa ali nazo.
Kuopsa kogwiritsa ntchito ma statins
Kafukufuku waposachedwa anena kuti odwala omwe ali ndi matenda a shuga a 2 komanso opaleshoni yayikulu kwambiri omwe amagwiritsa ntchito statin nthawi zambiri amakhala ndi malo ochepa kwambiri kuposa odwala omwe samakonda kugwiritsa ntchito ma statins. Mu gulu laling'ono la omwe sanamwe mankhwalawo, kuchuluka kwa zomwe atherosselotic zolembera adayamba kuchuluka atayamba kumwa mankhwala. Anthu ambiri omwe amatenga ma statins amawalekerera bwino. Koma anthu ena amakumana ndi zovuta zina, zomwe zina mwa izi ndi:
- Mutu.
- Kusowa tulo komanso kusokonezeka kwa tulo.
- Kupweteka kwa minofu, kumva, kapena kufooka (myalgia).
- Kugona.
- Chizungulire
- Mseru kapena kusanza.
- Mimba kukokana kapena kupweteka.
- Kufalikira ndi kusanja.
- Kutsegula m'mimba.
- Kudzimbidwa
- Zowombera.
Kafukufuku wina walembanso za zoyipa, kuphatikizapo izi:
- kuwonongeka kwa chiwindi ndi kapamba chifukwa cha kuchuluka kwa michere yomwe imachitika chifukwa cha kumwa mankhwalawa;
- kuwonongeka kwa minofu komwe kungayambitse kuchepa kwa minofu ya minofu, kulephera kwa impso, ndi kufa;
- kuchuluka kwa shuga wamagazi ndi chiopsezo chachikulu chotenga matenda a shuga a 2;
- kuchepa kwa kukumbukira, kukhumudwa, kuyiwala (komwe kumatha kukhala amnesia) ndi zovuta zina zam'mitsempha zomwe zawonedwa kuti zimayimitsidwa atangoyamba kugwiritsa ntchito ma statins;
- kusowa pogonana.
Ngati wodwala ali ndi ululu wosamveka kapena kupweteka kwa minofu, kumva kapena kufooka mukamamwa mankhwalawo, muyenera kufunsa dokotala. Amayi oyembekezera kapena odwala omwe ali ndi vuto la chiwindi chodwala kapena chodwala sayenera kugwiritsa ntchito ma statins.
Pankhani imeneyi, ndi dokotala yekha amene ayenera kuyambitsa mankhwala a gululi, mosamala zonse zabwino komanso zoipa.
Kwa odwala ambiri, ngakhale ali ndi matenda amtima, palibe chifukwa chofunikira chamankhwala amtunduwu. Mothandizirana ndi izi, dziko lonse lapansi likuyang'ana njira zotsitsira cholesterol yopanda ma statins.
Statin yopanda cholesterol yotsika
Ndi mankhwala ati omwe amachepetsa cholesterol kupatula ma statins? Pali mankhwala ena ambiri omwe amachepetsa mafuta a cholesterol, ndipo amakhala ndi zovuta zochepa. CoQ10 ndi antioxidant wopezeka mu khungu lililonse m'thupi la munthu.
Udindo waukulu wa CoQ10 ndikusintha michere kukhala mphamvu kuti ikule ndi kusamalira maselo. Chida ichi chimayambitsa kupanga ma enzyme omwe amagwiritsidwa ntchito kugaya chakudya limodzi ndi michere ina yofunika. Monga antioxidant, imatetezanso maselo ku zowonongeka zomwe zimayambitsidwa ndi ma free radicals. Kafukufuku watsimikizira kuti CoQ10 imachepetsa chiwopsezo cha kupsinjika kwa mtima ndikuchepetsa lipoproteins (zomwe zimadziwika kuti "cholesterol" yoyipa).
Tsoka ilo, kafukufuku wasonyeza kuti ma statins amathanso kuchepetsa othandizira thupi a CoQ10. Chifukwa chake, ngati wodwalayo akugwiritsa ntchito mankhwalawa, ndikofunika kumwa mankhwala a CoQ10 kuti muchepetse kupweteka kwa minofu, muteteze chiwindi kuti chisaoneke komanso kupewa kupezeka kwa zotsatirapo zoyipa zomwe zimachitika chifukwa cha mankhwalawo.
Chinthu china chotsitsa cholesterol ndi yisiti yampunga wofiira, yomwe imapangidwa ndi kupesa mpunga ndi mitundu yosiyanasiyana ya yisiti ya Monascus purpureus. Choyambitsa chake chimakhala ndi zosakaniza zingapo zomwe zimathandizira kuwongolera cholesterol, kuphatikizapo sterols, isoflavones ndi mafuta a monounsaturated acids. Monacolin K, yomwe ndi gawo la kuchotsedwako, ndi mankhwala achilengedwe omwe ali ndi mawonekedwe ofanana ndi mankhwala a Lovastatin ndi Mevinolin.
Kafukufuku akuwonetsa kuti kuwonjezera yisiti yampunga wofiyira kumapangitsa kutsika kwa 33% pama lipoproteins otsika, komanso kuwonjezeka kwa lipoproteins okwera kapena cholesterol yabwino.
Niacin ndi omega-3 mafuta acids
Kuyambira m'ma 1950s, niacin kapena Vitamini B3 akhala akupatsidwa mankhwala othandiza kuchepetsa mafuta a cholesterol ndi triglycerides. Komabe, imakhala ndi vuto limodzi lalikulu: kutengera mlingo, niacin imatha kuyambitsa redness ndi kuyabwa.
Komabe, pali njira ina yabwino. Inositol hexanacinate ndi gulu lopulumutsidwa nthawi mamolekyulu asanu ndi limodzi a niacin omwe amapereka phindu la vitamini B wopanda mavutidwe a chiwindi.
Enositol hexanacrate yatsimikiziridwa kuti ndi yothandiza, makamaka pochotsa mafuta ochuluka m'mitsempha yamagazi. Matendawa amatchedwa hyperlipidemia ndipo ali pachiwopsezo chachikulu cha matenda a mtima ndi matenda a mtima.
Kuchepetsa mafuta a cholesterol wopanda mankhwala kumachitika bwino ndi niacin kapena vitamini B-3. Uwu ndi njira yabwino kwa anthu omwe samvera bwino mankhwala ena, chifukwa mavuto ake ndi ofatsa komanso ocheperako.
Anthu omwe amamwa mankhwalawa akhoza kupeza zotsatirazi:
- mawonekedwe ofiira
- mutu
- kudzimbidwa
- thukuta;
- Chizungulire
- nseru
Ngati chithandizo chankhanza kwambiri chikufunika pochiritsa cholesterol yayikulu, gulu la mankhwala lotchedwa fibrate nthawi zambiri limayikidwa.
Kwa zaka 200 zapitazi, kuchuluka kwa mafuta omega-6 mpaka omega-3 acids m'zakudya za anthu kwayenda bwino. Zinthu izi zimathandiza kulimbana bwino ndi cholesterol yambiri, komanso zimathandizanso kuteteza kuchuluka pakati pa lipoproteins yotsika komanso yayikulu.
Munthu amafunika mafuta ochulukirapo a omega-3 ndi omega-6 mu zakudya zawo kuti akhale athanzi. Tsoka ilo, menyu wamba amapereka omega-6 ochulukirapo komanso osakwanira a omega-3 acid acids.
Akatswiri amati kuchuluka kwa mbali imodzi yokha ndiye komwe kumayambitsa matenda a mtima.
Cholesterol mayamwidwe zoletsa ndi sequestrants
Ngati ma statins si njira yabwino, kapena ngati wodwala akuvutika ndi zovuta, dokotalayo angamupatsenso mankhwala ena ochizira cholesterol yayikulu. Njira ina yodziwika ndi cholesterol mayamwidwe.
Mankhwalawa salola kuti matumbo ang'onoang'ono azitha kuyamwa bwino mafuta a cholesterol. Ngati sichingamwe, cholesterol siyofika m'magazi. Mankhwala okhawo omwe akupezeka pamsika ndi Ezetimibe. Mankhwalawa amatha kuphatikizidwa ndi ma statins pazotsatira zothamanga. Komabe, madokotala ambiri amatenga Ezetimibe chokhacho ndikuphatikiza ndi zakudya zamafuta ochepa kuti zithandizire kuchepetsa cholesterol.
Njira ina yochepetsera cholesterol yopanda ma statins ndikugwiritsa ntchito bile acid yomanga kapena othandizira. Mankhwalawa amagwira ntchito pomanga bile m'matumbo, kutsekereza mayamwidwe a cholesterol. Kugwira bwino ntchito kwa ndalamazi sikokwanira ngati mankhwala ena, chifukwa nthawi zambiri amagwiritsidwa ntchito ndi anthu omwe ali ndi cholesterol, yomwe imangokulitsidwa pang'ono. Mankhwalawa amathanso kupangitsa kuti mavitamini azitha kuchepa mosavuta. Kusowa kwa Vitamini K ndizowopsa makamaka chifukwa ndi vitamini yemwe amayambitsa dongosolo la heestatic.
Bile acid sequestrants ndi ma polymeric opanga omwe amasinthana anions, monga chloride ions, a bile acids. Chifukwa chake, iwo bile bile acid. Chiwindi chimapanga ma asidi ambiri a bile kuti m'malo mwa omwe atayika. Popeza thupi limagwiritsa ntchito cholesterol kupanga ma asidi a bile, amachepetsa kuchuluka kwa cholesterol yocheperako yomwe imazungulira m'magazi. Bile acid sequestrants ndi ma polymer akuluakulu, ndipo samatengeka kwambiri kuchokera m'matumbo kulowa m'magazi.
Chifukwa chake, mankhwalawa omwe ali ndi bile acid omwe amaphatikizana ndi mankhwalawa amathandizidwa kudzera m'mimba.
Natural cholesterol kutsitsa wothandizira
Zithandizo zachilengedwe zawonekeranso kuti zimapangitsa kuchepa kwa cholesterol.
Komabe, kugwiritsa ntchito kwawo kuyenera kutsagana ndi kusintha kwa moyo wawo.
Zakudya zochepa za cholesterol ziyenera kudyedwa. Ndikofunika kuti muzichita zolimbitsa thupi.
Kuphatikiza ndi izi, izi zimathandizanso:
- Garlic.
- Oat chinangwa.
- Artichoke.
- Barele
- Blond psyllium.
Ngati mukufuna kutsitsa cholesterol yanu, chinsinsi ndikungosintha chakudya cham'mawa. Kuphatikizidwa kwa oats m'mawa kumatha kuchepetsa kuchuluka kwa lipoprotein otsika ndi 5.3% m'milungu 6 yokha. Izi zimaperekedwa ndi beta-glucan - chinthu mumafuta omwe amamwa cholesterol, potero kupewa kutulutsa ma cholesterol. Mtedza ulinso bwino pakuchepetsa cholesterol, koma chifukwa cha zomwe amapeza kwambiri ma calorie, cholinga chawo ndizochepa.
Ndi kuvomerezedwa ndi adotolo, amatha kuwonjezedwa mosavuta muzakudya. Ndikofunika kudziwa kuti ngati pali mankhwala omwe dokotala akukulemberani, kumwa mankhwala achilengedwe kuti muchepetse cholesterol sichili chifukwa chosiya kumwa mankhwalawa.
Kusankha bwino kwambiri kwamankhwala kumatengera zinthu zambiri. Dokotala asanalembe mankhwala chamankhwala ena, katswiri amadziwa za mbiri ya wodwalayo, kuopsa kwa matenda amtima wamunthuyu, ndikuwunikanso moyo wa wodwalayo. Madokotala ambiri amakonda kuyamba kulandira chithandizo posintha kadyedwe komanso masewera olimbitsa thupi. Ngati izi zitatha, dokotalayo amakupatsani chithandizo chamankhwala. Ndikosatheka kusintha mulingo kapena mtundu wa mankhwalawo popanda upangiri wa zamankhwala, chifukwa izi ndizodzala ndi kusakhalapo kwa chithandizo chamankhwala, kapena, moyipitsitsa, kukulitsa zovuta.
Komanso, kukanidwa kwa mankhwalawa kumawonjezera mtengo wawo. Ngakhale kuti mapiritsiwa ayenera kumwa tsiku lililonse komanso osasokoneza, ma statin amakhala katundu osati chiwindi chokha, komanso chikwama. Ndemanga zenizeni za gulu la mankhwalawa nthawi zambiri zimakhala zopanda ndemanga zoyipa, chifukwa mankhwalawa amatha kuonekera kwambiri kuposa zovuta.
Zambiri zokhudzana ndi ma statins zimaperekedwa kanema munkhaniyi.
