Heinemox: Mankhwala ntchito

Mapiritsi a Heinemox amatha kuchotsa kutupa komwe kumachitika chifukwa cha ntchito ya anaerobic, anti-bacteric acid komanso mabacteria atypical. Pofuna kupewa zoyipa, mankhwalawa amayenera kuvomerezedwa ndi adokotala.

Dzinalo Losayenerana

Moxifloxacin (moxifloxacin).

ATX

J01MA14.

Mankhwala a antimicrobial akugulitsidwa monga mapiritsi a 400 mg a moxifloxacin.

Kutulutsa mafomu ndi kapangidwe kake

Mankhwala a antimicrobial akugulitsidwa mwanjira ya mapiritsi a 400 mg a moxifloxacin (gawo logwira ntchito).

Zina zomwe zili motengera:

• anhydrous colloidal silicon dioxide;
• croscarmellose sodium;
• ma cellcose a cellulose;
• magnesium wakuba;
• ufa wonyezimira wa talcum;
• sodium lauryl sulfate;
• Macrogol 3000;
• soya lecithin;
• oxide wofiira wachitsulo;
• White Opadry 85G58977.

Zotsatira za pharmacological

Mankhwalawa ndi angapo a fluoroquinolones ndipo ali ndi tanthauzo la bactericidal. Yogwira motsutsana ndi anaerobes ambiri, ma tizilombo tating'onoting'ono, othandizira acid (kuphatikizapo gram-negative ndi gram-gerins zabwino).

Zinthu zomwe zimapanga maziko a mapiritsi zimaletsa michere ya DNA ya mabakiteriya, kupangitsa kuti akule komanso kubereka. The achire ntchito ya moxifloxacin zimatengera mwachindunji kuchuluka kwa zosakaniza mu minofu ndi madzi am`magazi.

Pakati pa njira ya fluoroquinolone mndandanda, zovuta zotsutsa zinajambulidwa. Koma ma anaerobes ambiri komanso mabakiteriya abwino omwe amakhala ndi ma fluoroquinolones ena amamva kwambiri zovuta za moxifloxacin.

Zinthu zomwe zimapanga maziko a mapiritsi zimaletsa michere ya DNA ya mabakiteriya, kupangitsa kuti akule komanso kubereka.

Pharmacokinetics

Moxifloxacin amakamizidwa wathunthu komanso nthawi yochepa. Cmax imayimiriridwa pamphindi 30-240. The bioavailability wa MS ukufika 90%. Kuchuluka kwa thunthu kumawonedwa ndi bronchial mucous nembanemba, sinuses ndi zimakhala zam'mimba. Amawachotsa pamodzi ndi ndowe komanso mkodzo. Pafupifupi theka la moyo ndi maola 12.

Zizindikiro zogwiritsidwa ntchito

Njira zotsatirazi zotupa ndi zopatsirana zomwe zimapangidwa ndi tizilombo tating'onoting'ono timayang'ana mankhwala:

• chibayo chopezeka pagulu chopupulitsidwa ndi Streptococcus anginosus ndi Streptococcus milleri;
• pachimake gawo la matenda;
• sinusitis (pachimake), zotumphukira ndi tizilombo toyambitsa matenda;
• matenda opatsirana a m'mimba (kuphatikizapo matenda a polymicrobial);
• matenda a pakhungu ndi zotupa zofewa;
• matenda a m'matumbo otupa, kuphatikizapo endometritis ndi salpingitis.

Heinemox analamula kuti yotupa matenda a m'chiuno ziwalo.

Ndi matenda apakhungu, Heinemox ndi mankhwala.

Thrombomagum sinafotokozeredwe kuwonongeka kwa kupuma.

Kumwa mankhwalawa ndi mankhwala a chibayo.

Ndi sinusitis, ndichizolowezi kupatsa Heinemox.

Contraindication

Mankhwalawa sagwiritsidwa ntchito pazinthu izi:

• ziwengo kwa soya ndi / kapena mtedza;
• Hypersensitivity kuti moxifloxacin;
• Kuwonongeka kwa minofu ya Tendon pambuyo pa quinolone;
• kuphatikiza ndi antihistamines kuwonjezera nthawi ya QT (Terfenadine, Astemizole), ndi antibacterial mankhwala (Halofantrine);
• odwala omwe ali ndi vuto lalikulu la chiwindi ndi impso;
• zaka zazing'ono.

Wothandizira antimicrobial amalembedwa mosamala matenda amanjenje, limodzi ndi kupsinjika, ma psychoses, proarrhythmic reaction, komanso hepatic cirrhosis komanso kuphatikiza ndi mankhwala omwe amachepetsa mulingo wa potaziyamu m'thupi.

Ngati wodwala sagwirizana ndi soya, kumwa mankhwalawo ndizoletsedwa.

Kuwonongeka kwa tendon minofu pambuyo pa quinolone mankhwala ndi contraindication kumwa mankhwalawa.

Ndi mawonekedwe ofatsa a impso ndi chiwindi, mankhwalawa ayenera kumwedwa mosamala.

Msinkhu wocheperako - kuphwanya kugwiritsa ntchito mankhwala a Heinemoks.

Momwe mungatenge Heinemox

Mapiritsi a antimicrobial ayenera kumwedwa pakamwa yonse, kutsukidwa ndi madzi. Ndikofunika kuchita izi mukatha kudya.

Mlingo wambiri:

• chibayo (mitundu yopezeka m'deralo): mankhwalawa amatengedwa mu mlingo wa 400 mg; mankhwala kumatenga 1 mpaka 2 milungu;
• bronchitis (ndi exacerbation): tsiku lililonse kuchuluka kwa mankhwala - 400 mg; nthawi yovomerezeka ndi masiku 5-10;
• sinusitis ya bakiteriya: 400 mg ya mankhwala zotchulidwa patsiku; Kutalika kwa mankhwala - 1 sabata;
• khungu / subcutaneous matenda: mlingo - 400 mg; Kutalika kwa mankhwala kuyambira 1 mpaka 3 milungu;
• intra-m'mimba matenda opatsirana: Mlingo - 400 mg; nthawi ya chithandizo - kuyambira masiku 5 mpaka 14;
• zotupa zotupa (zosavuta), zotulutsidwa m'matumbo amchiberekero: pafupifupi tsiku lililonse - 400 mg; Nthawi yayitali ya masabata awiri.

Mapiritsi a antimicrobial ayenera kumwedwa pakamwa yonse, kutsukidwa ndi madzi.

Ndi matenda ashuga

Mukamamwa mankhwala, odwala matenda ashuga ayenera kuyang'anira kuchuluka kwa shuga m'magazi.

Zotsatira zoyipa za Heinemox

Kuchokera minofu ndi mafupa

• myalgia;
• arthralgia;
• kuchuluka minofu kamvekedwe;
• minofu kukokana;
• kufooka
• nyamakazi;
• kuchuluka kwa myasthenia gravis;
• kuwonongeka kwa tendon.

Matumbo

• zilonda zam'mimba;
• nseru
• kutsegula m'mimba
• chisangalalo;
• kuchepa kwa chakudya;
• stomatitis
• dysphagia;
• colitis (mawonekedwe a pseudomembranous);
• gastroenteritis.

Pa ntchito ya mankhwala, minyewa kukokana kumachitika.

Ululu pamimba ndi zotsatira zoyipa za mankhwala a Thrombomag.

Mankhwala ndi Heinemox, kuchepa kwa chilakolako chokwanira kumatha.

Mankhwala amatha kuyambitsa matenda otsegula m'mimba.

Mukumwa mankhwala a thrombomag, mseru komanso kusanza kumatha kuchitika.

Hematopoietic ziwalo

• kuchuluka kwa INR / kutalika kwa PV;
• kusintha kwa thromboplastin ndende;
• leukopenia;
• neutropenia;
• thrombocythemia;
• thrombocytopenia;
• kuchepa magazi

Pakati mantha dongosolo

• Chizungulire
• dysesthesia / paresthesia;
• kuwonongeka mu kukoma;
• chisokonezo;
• kusowa tulo
• Kukhumudwa
• vertigo;
• kutopa
• kugona
• zochitika zamankhwala;
• mavuto ndi ntchito yolankhula;
• mwachidwi.

Mukumwa mankhwalawa, kuoneka kwa kufooka wamba ndikotheka.

Chizungulire chosatha ndi zotsatira zoyipa za kutenga Aspirin.

Kusowa tulo ndi chimodzi mwazotsatira za mankhwalawa.

Heinemox angayambitse kugona.

Kuchokera pamtima

• kuchuluka kwa nthawi ya QT mwa anthu omwe ali ndi vuto la hypokalemia;
• kuchuluka / kuchepa kwa kuthamanga kwa magazi;
• yamitsempha yamagazi tachyarrhythmia;
• mitundu yosakhazikika ya arrhythmia;
• kugaya mtima.

Kuchokera kumbali ya kagayidwe

• Hyperuricemia
• kuchuluka kwa bilirubin;
• hyperglycemia;
• Hyperlipidemia.

Matupi omaliza

• eosinophilia;
• anaphylactic zimachitika;
• zotupa
• Edema ya Quincke;
• laryngeal kutupa (koopseza moyo).

Mavuto akumva ndi dyspnea nthawi zina amatha kuwonekera.

Pa chithandizo ndi Heinemox, kuwonetsedwa kwa vuto la mtima ndikotheka.

Zokhudza mphamvu pakuwongolera njira

Njira zochokera ku gulu la fluoroquinolones zimatha kubweretsa kusintha kwa zochitika zama psychomotor zikagwidwa, motero pakadali pano ndikusiya kuyendetsa galimoto ndi zina zomwe zingakhale zoopsa.

Malangizo apadera

Munthawi yogwiritsira ntchito mankhwala osokoneza bongo, milandu ingapo yokhudza kuwonekera kwa zilonda zamkati zamkati inalembedwa (epermal toxic necrolysis, Stevens-Johnson syndrome). Wodwala ayenera kudziwitsidwa pasadakhale kuti ngati pali zovuta zina, muyenera kufunsa dokotala.

Ndiosafunika kugwiritsa ntchito mankhwalawa pochiza matenda opatsirana omwe amayamba chifukwa cha mabakiteriya osagwirizana ndi methicillin.

Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere

Akatswiri amaletsa kugwiritsa ntchito mankhwalawa panthawi yoyamwitsa komanso pakati.

Akatswiri amaletsa kugwiritsa ntchito mankhwalawa panthawi yoyamwitsa.

Gwiritsani ntchito mu ukalamba

Mwa odwala, chidwi cha mankhwalawa chimachulukitsidwa kwambiri, motero, mankhwalawa amayenera kusankhidwa poganizira thanzi lawo.

Kupatsa ana

Osapatsidwa zaka 18 zakubadwa.

Gwiritsani ntchito ntchito yolakwika ya chiwindi

Mosamala zotchulidwa mavuto ndi thupi.

Mankhwala osokoneza bongo a Heinemox

Poterepa, ndikofunikira kulabadira chithunzi cha chipatala. Mankhwala osokoneza bongo - othandizira, potengera kuwunika pogwiritsa ntchito ECG. Kukonzekera kwa kaboni kokhazikitsidwa kumalepheretsa kwambiri zotsatira za moxifloxacin.

Kukonzekera kwa kaboni kokhazikitsidwa kumalepheretsa kwambiri zotsatira za moxifloxacin.

Kuchita ndi mankhwala ena

Pogwiritsa ntchito munthawi yomweyo maantacid, ma multivitamini ndi mankhwala osakanikirana, mayamwidwe amachepetsa ndipo kuchuluka kwa plasma kwa moxifloxacin kumachepa.

Pogwiritsa ntchito nthawi yomweyo mankhwala omwe ali ndi fluoroquinolones, pamakhala chiwopsezo chowonetsedwa.

Ranitidine amathandiza kuchepetsa kuyamwa kwa moxifloxacin.

Kuyenderana ndi mowa

Wopanga sapereka chidziwitso chokhudza kuphatikiza kumeneku.

Avelox ndi analogue ya mankhwala a Heinemox.

Misonkho ya mankhwala a Heinemox - Maxiflox.

M'malo mwa Heinemox, Vigamox nthawi zina amakhazikitsidwa.

Rotomox nthawi zina amakhazikitsidwa m'malo mwa Heinemox.

Analogi

• Avelox;
• Maxiflox;
• Vigamox;
• Moksimak;
• Moxigram;
• Aquamax;
• Alvelon MF;
• Ultramox;
• Simoflox;
• Rotomox;
• Plevilox;
• Moflaxia.

Kupita kwina mankhwala

Mapiritsi Othandizira

Mtengo

300-380 rub. pa paketi No. 10 (mapiritsi 10, okhala ndi mafilimu).

Zosungidwa zamankhwala

Mankhwalawa azikhala pamalo akutali ndi ana pamalo otentha osapitirira + 25 ° C.

Tsiku lotha ntchito

Zaka 5

Wopanga

Highglans Laboratories HTP. LTD (India).

Ndemanga

Olga Shapovalova, wazaka 39, Irkutsk

Ndimakonda kumwa mankhwalawa pamene bronchitis yanga imayamba kuwonda. Imagwira modekha komanso yotsika mtengo. Poyamba ndimagwiritsanso ntchito mankhwala ena, koma kuchokera pamenepa sindimakumana ndi zovuta.

Victor Koklyushnikov, wazaka 45, Vladimir

Anawachiritsa ndi mapiritsi a sinusitis, popeza amalepheretsa mabakiteriya osavomerezeka ndi gramu. Adapita kukagwira ntchito patadutsa milungu 1.5 atatha chithandizo. Zizindikiro zamankhwala zabwerera mwakale, mkhalidwe umakhala bwino.