Kuti muchepetse matenda opatsirana, pamafunika mankhwala opha tizilombo omwe angalimbane ndi microflora ya bakiteriya ndipo sangavulaze wodwala. Amikacin ndi yoyenera kuchitira odwala omwe akhudzidwa ndi mitundu yosiyanasiyana ya tizilombo.
ATX
Nambala ya ATX ndi J01GB06.
Amikacin ndi yoyenera kuchitira odwala omwe akhudzidwa ndi mitundu yosiyanasiyana ya tizilombo.
Kutulutsa mafomu ndi kapangidwe kake
Kutulutsa kwa maantibayotiki ali mumtundu wa ufa womwe umagwiritsidwa ntchito kukonza njira. Chombochi chimayikidwa mu ma ampoules. Phukusili lili ndi mabotolo a 1, 5, 10 kapena 50.
The yogwira mankhwala amikacin sulfate ilipo kuchuluka kwa 250, 500 kapena 1000 mg. Zowonjezera ndi:
- madzi a jakisoni;
- sodium hydrogen phosphate;
- disodium edetate.
Zotsatira za pharmacological
Mankhwala ndi a semisynthetic aminoglycosides. Mankhwalawa ali ndi bacteriostatic ndi antibacterial. Tizilombo toyambitsa matenda tosagwirizana ndi mtundu wa aerobic komanso ma gram okhala ndi ma gramu ena amakhala ndi chidwi ndi mankhwalawo.
Pharmacokinetics
Maantibayotiki amalowa m'thupi lonse. Ndi njira ya makonzedwe a makonzedwe, imakwaniritsidwa kwathunthu komanso mwachangu.
Amachotseredwa osasintha kuchokera m'thupi. Mankhwala akhoza kulowa placental chotchinga. Chosakaniza chophatikizika chimapezeka mu amniotic fluid.
Zizindikiro zogwiritsidwa ntchito
Kugwiritsa ntchito kwa chida kukuwoneka pamaso pa zinthu zotsatirazi:
- sepsis mu akhanda;
- matenda am'mimba
- matenda a biliary thirakiti;
- kuwotcha, limodzi ndi kulowerera kwa microflora ya pathogenic;
- kuwonongeka kwa mafupa ndi mafupa;
- matenda am'mimba;
- chotupa cha m'mapapo;
- zotupa za purulent pakhungu;
- matenda opatsirana pambuyo opaleshoni;
- chibayo.
Kugwiritsidwa ntchito kwa amikacin kumasonyezedwa matenda opatsirana pamimba.
Contraindication
Kukhalapo kwa zotsatirazi zamatenda komanso zovuta ndizotsutsana ndikusankhidwa kwa mankhwala:
- makutu amitsempha;
- Hypersensitivity zikuchokera mankhwala;
- kulakwitsa kwambiri kwa impso;
- chidwi chachikulu ndi mankhwala ochokera ku gulu la aminoglycoside;
Momwe mungagwiritsire ntchito
Pamaso jakisoni, tikulimbikitsidwa kuti mutenge zitsanzo kuti mupeze kuchuluka kwa chidwi cha mankhwalawa. Chidachi chimagwiritsidwa ntchito pokonzekera intramuscular kapena intravenous.
Odwala achikulire amapatsidwa jakisoni katatu patsiku.
Mankhwalawa kumatenga masiku 10. Mlingo amasankhidwa payekha, chifukwa momwe wodwalayo alili, kuchuluka kwa chitukuko cha matendawa komanso kulemera kwa thupi kuyenera kuganiziridwanso.
Zomwe ndi kubereketsa
Ngati mukusamba kugwiritsa ntchito 2-3 ml ya madzi osungunuka, oyenera jakisoni. Mankhwalawa amapaka jakisoni wamadzimadzi, kenako ndikugwiritsidwa ntchito mongaalangidwa.
Pofuna kuchepetsa ululu pakumwa mankhwala, Novocain 0,5% kapena Lidocaine 2% angagwiritsidwe ntchito. Mukasakaniza zigawo zimatengedwa zofanana.
Kodi ndizotheka kumwa mankhwalawa chifukwa cha matenda ashuga
Kugwiritsa ntchito amikacin sikuletsedwa ndi malangizo ogwiritsa ntchito. Pamaso mankhwala ayenera kuganizira wodwalayo.
Zotsatira zoyipa
Mankhwala amatha kuyambitsa mavuto.
Pakati mantha dongosolo
Maonekedwe amtundu wovuta kuchokera ku dongosolo lamkati wamanjenje kumabweretsa zotsatirazi:
- kugona
- kumva kusamva, m'malo ovuta, kutayika kwa ntchito kumatha;
- Vuto lama vestibular;
- kuphwanya kwa mitsempha yotulutsa.
Kuchokera kwamikodzo
Zotsatira izi ndizofala:
- kukhalapo kwa mapuloteni mumkodzo;
- Kutulutsa kwamkodzo;
- kukhalapo kwa maselo ofiira am'mimba mu mkodzo.
Nthawi zina, wodwalayo amayamba kulephera.
Matupi omaliza
Ndi kukula kwa thupi lawo siligwirizana, zizindikiro zimawonekera:
- angioedema;
- Khungu;
- mankhwalawa;
- dermatitis;
- zotupa pakhungu;
- kuwonongeka kwa makoma a venous (phlebitis).
Malangizo apadera
Odwala ndi mkhutu aimpso ntchito ayenera kusintha mlingo. Kuchuluka kwa mankhwalawa kumasankhidwa poganizira kuchuluka kwa creatinine mu seramu yamagazi kapena kuwerengera phindu.
Kuyenderana ndi mowa
Kumwa mowa panthawi yamankhwala kumakulitsa zovuta zomwe zimayambitsa chiwindi. Kuphatikiza apo, mavuto amabwera.
Zokhudza mphamvu pakuwongolera njira
Ma Antibiotic amatha kukhala ndi vuto loyendetsa.
Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere
Pa mkaka wa pakati ndi pakati, ndizoletsedwa kugwiritsa ntchito mankhwalawa.
Kupangira Amikacin kwa ana
Mankhwalawa amatha kugwiritsidwa ntchito pochiza ana. Mlingo wake umasankhidwa poganizira kulemera kwa wodwalayo.
Gwiritsani ntchito mu ukalamba
Kwa anthu okalamba, mankhwalawa amadziwitsidwa mosamala.
Bongo
Zizindikiro za bongo ndi:
- ludzu
- kulephera kupuma;
- mavuto pokodza;
- kumva kuwonongeka kapena kutayika;
- kusanza ndi mseru;
- chiwindi ntchito;
- Chizungulire
- kutayika kwathunthu kapena pang'ono kwa mgwirizano wa minyewa yoyenda (ataxia).
Zizindikiro za bongo wa Amikacin ndi ludzu.
Nthawi yomweyo pezani thandizo kuchipatala pamaso pazomwe zalembedweratu.
Kuchita ndi mankhwala ena
Otsatirawa amakambirana a Amikacin ndi mankhwala ena:
- kumawonjezera mwayi wopsinjika mtima mukamagwiritsa ntchito ma neuromuscular transmission blockers kapena ethoxyethane;
- Mphamvu ya mankhwala amachepetsa kugwiritsa ntchito ma penicillin motsutsana ndi kukula kwa aimpso;
- Zotsatira zoyipa za ziwalo za makutu zimawonjezeka pamene mukumwa mankhwala a Cisplatin kapena loopte;
- kuchuluka kwa poizoni pa impso chifukwa chogwiritsa ntchito NSAIDs, Vancomycin, Polymyxin, cyclosporin kapena Enfluran.
Kuphatikiza apo, maantibayotiki sagwirizana ndi mankhwala otsatirawa:
- potaziyamu mankhwala enaake (kutengera kapangidwe ka yankho);
- Erythromycin;
- cephalosporins;
- Vitamini C
- Nitrofurantoin;
- Chlortiazide;
- tetracycline mankhwala (kutengera ndende yankho ndi kapangidwe kake).
Analogi
Zofananazo zimakhala ndi njira:
- Ceftazidime ndi mankhwala omwe mankhwala omwe amagwira ndi 0,5 kapena 1 g wa ceftazidime. Mankhwalawa ali ndi bactericidal.
- Ceftriaxone ndi mankhwala a gulu la mankhwala a cephalosporin. Mankhwalawa cholinga chake ndikuwononga makoma a ma cell a tizilombo toyambitsa matenda.
- Kanamycin ndi yankho la aminoglycoside. Mankhwala tikulephera kukula kwa microflora pathogenic.
- Cefixime ndi mankhwala a m'badwo wachitatu wa cephalosporins. Mankhwalawa samadziwika ndi beta-lactamase, amagwira ntchito pamaso pa gram-negative ndi gram-microflora. Amapezeka mu mawonekedwe a ufa ndi mapiritsi am'kamwa.
- Lendacin ndi mankhwala omwe zotsatira zake zowonongeka zimafalikira pamagciwane ambiri.
- Sulperazone ndi mankhwala osokoneza bongo omwe ali ndi zotsatira zoyipa.
- Sizomycin ndi mankhwala okhala ndi mawonekedwe osiyanasiyana a antibacterial.
Kupita kwina mankhwala
Kuti mugule mankhwala, muyenera kulembetsa kuti mulembe mankhwala mu Latin mukamalankhula ndi dokotala.
Mtengo wa Amikacin
Mtengo wa mankhwalawa ndi 40-200 rubles.
Kusungidwa kwa mankhwala Amikacin
Malo osungirako ayenera kukhala ouma. Mankhwalawa ayenera kutetezedwa ku dzuwa.
Ana sayenera kulandira mankhwalawo kwaulere.
Tsiku lotha ntchito
Ndizoyenera zaka 3.
Ndemanga za Amikacin
Olga, wazaka 27, Krasnodar
Mankhwalawa adalamulidwa kuchitira mwana wanga wamkazi, chifukwa adayamba matenda amatumbo. Amikacin adathandizidwa kudzera m'mitsempha. Mwanayo sanadandaule za ululu kapena mavuto ake, motero kumwa mankhwalawo kunayenda bwino. Pambuyo pa masiku atatu, mankhwalawa adasinthidwa ndi Ceftriaxone, koma palibe zotsatira zoyipa.
Sofia, wazaka 31, Penza
Mwana wake wamkazi atabadwa, adatenga matenda. Anapatsidwa jakisoni ndi Amikacin kwa masiku 5. Adotolo adati simungathe kupuma, apo ayi muyenera kuyambanso kulandira chithandizo. Njira yovomerezeka idatha, adatha kuchira msanga. Panalibe zovuta zoyipa. Pokhapokha nthawi zina osokoneza, koma chizindikirocho sichinatenge nthawi.
Elena, wazaka 29, Norilsk
Amikacin adathandizidwa ndi mwana wamkazi pamene kutentha kwake kudumpha panthawi yachangu. M'dipatimenti ya ana adapatsa jakisoni ndi mankhwalawa, ndiye adandiuza kuti ndiziwagwiritsa ntchito mankhwalawa kwa masiku angapo. Pa tsiku 3, mwana adawoneka mawanga pakhungu. Ndimayenera kuyimbira dokotala. Zidadziwika kuti izi ndizomwe thupi limachita. Pambuyo pa antibayotiki, ma antihistamines adatengedwa.
