Aspicor antiplatelet wothandizira adapangira kuti azigwiritsidwa ntchito kwa nthawi yayitali ndi odwala omwe ali pachiwopsezo chokhala ndi zovuta za thromboembolic.
Dzinalo Losayenerana
Mu Chilatini - Aspicor
Aspicor antiplatelet wothandizira adapangira kuti azigwiritsidwa ntchito kwa nthawi yayitali ndi odwala omwe ali pachiwopsezo chokhala ndi zovuta za thromboembolic.
ATX
B01AC06
Kutulutsa mafomu ndi kapangidwe kake
Mankhwala, omwe amagwira ntchito omwe ali acetylsalicylic acid, amapezeka mu mawonekedwe apiritsi ndi kuphatikizika kwapadera kwa enteric. Piritsi limodzi lili ndi 100 mg yogwira ntchito.
Mawonekedwe ake ndi mapiritsi a biconvex, oyera. Amapezeka m'matuza a zidutswa 10. 3, matuza 9 ndi malangizo ogwiritsira ntchito adatsekedwa pakatoni. Analogues a mankhwalawa amapezeka mwanjira ya mapiritsi a dravescent.
Zotsatira za pharmacological
Mphamvu ya antiplatelet ya mankhwalawa imaperekedwa ndi chinthu cha gulu la salicylates. Kupanga enzyme cycloo oxygenase, acetylsalicylic acid imathandizira kusokonekera kwa kapangidwe kazomwe michere ya minofu ya prostaglandin imatupa. Chifukwa cha kuwonekera kotere, mapulateleti amalephera kupanga ma thromboxane. Popanda enzyme iyi, maselo amwazi sangathe kuchulukana ndikuphatikizana ndi fibrin.
Mphamvu yowonetsera imasungidwa mu moyo wonse wamaselo.
Imakhala ndi zoletsa kupanga mapangidwe a prostacyclin ndi maselo am'mitsempha. Enzyme iyi imalepheretsa kuphatikiza kwa mawonekedwe. Kuletsa kaphatikizidwe kumachitika pokhapokha ngati pali chinthu china m'thupi. Mlingo wocheperako wa mankhwalawa suletsa kupangika kwa uhule.
Kupanga enzyme cycloo oxygenase, acetylsalicylic acid imathandizira kusokonekera kwa kapangidwe kazomwe michere ya minofu ya prostaglandin imatupa. Chifukwa cha kuwonekera kotere, mapulateleti amalephera kupanga ma thromboxane.
Mphamvu ya otsika Mlingo imatsimikiziridwa. Izi zimapangitsa kugwiritsira ntchito mankhwala ngati mankhwala a prophylactic. Sichikukhudzana ndimagazi omwe amapangidwa, koma amaletsa mapangidwe awo.
Kusintha kapangidwe ka fibrin, kumasula plasminogen, kumalimbikitsa kuyambitsa kwa fibrinolysis.
Pharmacokinetics
Chovuta ndi pakamwa. Amapangira kuti imalowe m'matumbo ang'ono. Mpaka 90% ndi chifukwa cha mapuloteni. Zimatenga pafupifupi maola atatu kuti mufikire pazomwe zimakhala.
Chifukwa cha hydrolysis, anyezi wa salicylic acid amapangidwa, omwe amagawidwa momasuka m'thupi. Akukumana ndi hepatic kagayidwe. Kwambiri odziwira mu acidic malo.
Chovuta ndi pakamwa.
Kupyola m'makoma amitsempha yamagazi ndimamolekyu a ionized acid okha omwe amalowa mu minofu, mphamvu inayake yamphamvu yomwe imawonjezereka kumalo achilengedwe. Kugwiritsa ntchito mankhwalawa mu acidosis kumakhala koopsa chifukwa cha kukhalapo kwa zinthu zomwe zingachitike chifukwa cha kuledzera.
Imakhala ndi kagayidwe, ndikupanga mankhwala ophatikizika ndi glycine, glucuronic acid. Amathira mkodzo. The renal tubules secrete mpaka 60% ya yogwira pophika ndi metabolites. Kuchotsa hafu ya moyo kumatengera mlingo wovomerezeka, acidity ya sing'anga.
Zomwe zimayikidwa
Mankhwala amapezeka Mlingo, wowerengeka chifukwa cha kukonzanso kwa nthawi yayitali. Imalepheretsa mapangidwe amu magazi ngati:
- pachimake myocardial infarction;
- mtima matenda a matenda kufala;
- angina pectoris.
Imalepheretsa mapangidwe amitsempha yamagazi ngati angina osakhazikika.
Perekani kwa odwala omwe ali pachiwopsezo cha kukhala ndi pulmonary embolism, coruteary corombary. Kugwiritsa ntchito mankhwalawa kumakhala koyenera ngati:
- matenda oopsa
- matenda a shuga;
- atherosulinosis, hyperlipidemia;
- kunenepa
- kuchuluka kwa nthawi yayitali;
- zinthu pambuyo opaleshoni ya mtima.
Kugwiritsa ntchito mankhwalawa kumakhala koyenera ngati munthu wanenepa kwambiri.
Amayikidwa kuti ateteze kubwereza kwa mtima mobwerezabwereza, kuchepa kwa kanthawi kochepa, thrombosis ya ziwiya zazikulu.
Contraindication
Chifukwa chazovuta zamankhwala omwe amapezeka pamankhwala, kugwiritsidwa ntchito kwake kumachepa ngati:
- zilonda zam'mimba zilonda;
- magazi
- opambana atatu a Ferian-Vidal;
- matupi awo sagwirizana ndi mankhwala a gulu la salicylate;
- mphumu ya bronchial, yopweteketsedwa ndi kugwiritsa ntchito mankhwala omwe si a steroidal;
- mimba
- mankhwala a methotrexate.
Sizingagwiritsidwe ntchito kuchiza ana ndi achinyamata.
Ndi chisamaliro
Chidwi chochulukirapo popereka mankhwala pamafunika:
- matenda a m'mapapo;
- polyposis ya mphuno, hay fever;
- matenda am'mimba ndi kuchuluka acidity;
- chiwindi ndi impso ntchito;
- matenda a magazi;
- kugwiritsa ntchito methotrexate;
- pamodzi mankhwala regimens;
- gout, hyperuricemia.
Kuchulukitsa chidwi mukamapereka mankhwala kumafuna matenda am'mimba omwe ali ndi acidity yayikulu.
Chithandizo chimafuna chisamaliro ngati odwala ali ndi matenda ophatikizika, kufunikira kwa mankhwala ena.
Momwe mungatengere Aspicore
Mapiritsi ayenera kumwedwa kwathunthu, kutsukidwa ndi madzi ambiri. Tengani nthawi yomweyo musanadye. Mlingo ndi nthawi yayitali ya chithandizo iyenera kutumizidwa ndi dokotala.
Popewa thrombosis, mankhwalawa amatchulidwa 100 mpaka 300 mg patsiku. Pazovuta zapachifuwa, ndikofunikira kutafuna piritsi loyambilira.
Ndi matenda ashuga
Kuphatikiza kwa Aspicore ndi mankhwala a hypoglycemic kumapangitsa kuchuluka kwa zotsatirazi. Choopseza cha hypoglycemia chimapangidwa. Ayenera kuyang'anira shuga, magazi, impso, chakudya,
Zotsatira zoyipa za Aspicore
Zotsatira zoyipa zomwe zimagwiritsidwa ntchito pogwiritsa ntchito mankhwalawa nthawi zambiri zimawonetsedwa ndi:
- khungu
- kugaya chakudya;
- chapakati mantha dongosolo;
- ziwalo zopanga magazi.
Zotsatira zoyipa zomwe zimagwiritsidwa ntchito pogwiritsa ntchito mankhwalawa nthawi zambiri zimawonetsedwa ndi ziwalo za hematopoietic.
Kukula kwa zotsatira zoyipa kumachitika chifukwa cha mphamvu ya yogwira zinthu pama receptor a malo aubongo, kulengedwa kwa michere yambiri m'magazi am'magazi.
Matumbo
Monga salicylates onse, imatha kupangitsa zizindikiro za dyspeptic. Zowonjezera, zomwe zimaphatikizapo ma oxygenase inhibitors, sizikulimbikitsidwa kuti zigwiritsidwe ntchito palimodzi. Kuphatikiza uku kumawonjezera chiopsezo cha kuyonekera kwa ulcerogenic Zotsatira zoyipa za mankhwalawa zimaphatikizapo kutulutsa magazi m'mimba.
Hematopoietic ziwalo
Supombocytopenia ikhoza kuchitika. Ndi kuchepa kwa phosphate dehydrogenase amachititsa hemolytic anemia.
Supombocytopenia ikhoza kuchitika. Ndi kuchepa kwa phosphate dehydrogenase amachititsa hemolytic anemia.
Pakati mantha dongosolo
Kudzikundikira kwa chinthu chogwira ntchito mu minyewa yaubongo kumawonetsedwa ndi phokoso lamakutu m'makutu, chizungulire. Aspicore metabolites amachititsa tinnitus yakanthawi popereka mankhwala akulu.
Kuchokera ku kupuma
Zotsatira zoyipa za kupuma zimawonetsedwa ndi kukula kwa bronchospasm, dyspnea wakunja. Zithunzizi zimapangitsa kuti zikhale zovuta kugwiritsa ntchito mankhwalawa pazolinga zomwe adakonza.
Zotsatira zoyipa za kupuma zimawonetsedwa ndi kukula kwa bronchospasm, dyspnea wakunja.
Matupi omaliza
Kulandila kungayambitse kuwoneka ngati zotupa pakhungu, edema la Quincke. Zomwe zimachitika mwadzidzidzi ndizochepa, zimafunikira chisamaliro. Zochita za anaphylactic mu anamnesis ndi nthawi yochotsa mankhwala.
Zokhudza mphamvu pakuwongolera njira
Pamaso pa zovuta zamtundu wamanjenje, ntchito yofunikira chidwi iyenera kusiyidwa.
Pamaso pa zovuta zamtundu wamanjenje, ntchito yofunikira chidwi iyenera kusiyidwa.
Malangizo apadera
Gwiritsani ntchito mankhwalawa nokha kupweteka ndi matenda oopsa ovomerezeka osaposa masiku atatu.
Kutha kuyambitsa magazi kumalepheretsa kugwiritsa ntchito mankhwalawa ngati othandizira kutupa. Mankhwala othandizira antiplatelet amayenera kuchitika ndikuwunika kuchuluka kwa magazi nthawi zonse. Kufufuza ndowe za magazi amatsenga ngati mungagwiritse ntchito nthawi yayitali ndikofunikira.
Pofuna kuonetsetsa kuti magazi ochepa kwambiri atayika panthawi yopanga maopaleshoni, kuphatikizapo matenda a m'mimba, mankhwalawa amayenera kutha sabata asanachite opareshoni.
Kugwiritsa ntchito mitundu yapadera ya kumasulidwa kwa mankhwalawa kumathandizira kuchepetsa kukhumudwitsa kwa salicylic acid.
Gwiritsani ntchito mu ukalamba
Ndi zaka, pharmacokinetics ya mankhwala amasintha:
- hepatic kagayidwe amachepetsa;
- kusintha kwa minofu;
- nthawi yochotsera ikula.
Kuchuluka kwa plasma albin, kuchepa kwa impso, kuwonjezereka kwa mphamvu yapadera ya adipose minofu kumapangitsa kuti pakhale kuchuluka kwa ntchito yogwira ntchito komanso kukulitsa mavuto.
Kugwiritsa ntchito mankhwala omwe ali ndi poizoni omwewo pakukalamba sikuvomerezeka.
Kukhalapo kwa matenda olumikizana ndi mankhwala a nthawi yayitali amafunikira kuwunika kwa serum creatinine komanso kuthamanga kwa magazi. Mankhwala osokoneza bongo amachititsa zotsatira zoyipa. Kugwiritsa ntchito mankhwala omwe ali ndi poizoni omwewo pakukalamba sikuvomerezeka.
Kupatsa ana
Zosagwira ntchito paubwana ndi unyamata. Ali ndi chiwopsezo chachikulu cha mavuto a hemorrhagic. Kugwiritsidwa ntchito kwa Aspicore kumayambitsa kukula kwa magazi, kupezeka kwa matenda amphumu. Simungathe kupereka mankhwala popanda kuikidwa ndi dokotala.
Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere
Osati zotchulidwa koyambirira kwa mimba. Pali chiwopsezo chachindunji cha mapangidwe obadwa nawo kwa mwana wosabadwa. Chiwopsezo chopereka mankhwala mu trimester yachiwiri iyenera kuvomerezeka.
Kulowa kwa chinthu chogwira ntchito kudzera mwa placenta kumayambitsa kukula kwa hemorrhagic syndrome. Kugwiritsa ntchito mankhwala oledzeretsa ndiwowopsa pangozi.
Kugwiritsa ntchito mankhwala oledzeretsa ndiwowopsa pangozi.
Kungogwiritsa ntchito kamodzi kakang'ono ka chinthucho sikukutsutsana poyamwitsa. Kutenga nthawi yayitali panthawiyi kumayenderana ndi kuthetsedwa kwa yoyamwitsa.
The ntchito aimpso kuwonongeka
Kupereka mankhwala kwa odwala omwe asinthika aimpso, kulephera kwaimpso ndikosayenera. Kuchepa kwa uric acid kumapangitsa kuti musavutike ngakhale pang'ono.
Gwiritsani ntchito ntchito yolakwika ya chiwindi
Kuphwanya hepatic kagayidwe kamachepetsa chilolezo ndi 30%, zomwe zimafuna kuti munthu asinthe. Fotokozani mankhwala a matenda a chiwindi ayenera kusamala.
Fotokozani mankhwala a matenda a chiwindi ayenera kusamala.
Mankhwala osokoneza bongo a Aspicore
Kukula kwa zizindikiro za poizoni kumatengera mlingo wa mankhwalawa. Mawonetseredwe azachipatala akukhazikika kwabasi amadziwika ndi:
- kusanza, kusanza;
- chizungulire
- kuwonongeka kwamawonekedwe;
- kusamva kwamakutu, kulira m'makutu;
- chikumbumtima.
Chizindikiro cha poizoni ndimankhwala chingakhale chizungulire.
Kuwoneka kwa zizindikiro za poyizoni kumafuna kuchepetsedwa msanga mu mankhwalawa, kuyang'aniridwa mosamalitsa kuchipatala.
Poizoni wowopsa wa salicylate amafunika kuchipatala mwachangu, chisamaliro chodzidzimutsa.
Zizindikiro za poizoni wamphamvu amadziwika ndi:
- ketoacidosis;
- malungo;
- Hyperventilation;
- kupuma alkalosis;
- kulephera kudziwa;
- kutsika kwakuthwa kwa shuga m'magazi;
- kulephera kwa mtima, kupuma kwamphamvu.
Zizindikiro za poizoni woopsa amadziwika chifukwa cha kusazindikira.
Odwala amafunika kulowetsedwa kwa mankhwala a alkaline, hemodialysis, kukonza electrolyte bwino komanso magazi. Chithandizo cha Syndrome zimayikidwa ngati pakufunika.
Mchere wambiri womwe umakhala ndi mchere wa salicylic umawonetsa kuchuluka kwa poyizoni komanso chidziwitso chovuta.
Kuchita ndi mankhwala ena
Kugwiritsa ntchito kwa salicylic acid ndi mankhwala am'magulu osiyanasiyana kuyenera kukhala koyenera. Kuyanjana kumawonekera pokhazikitsa njira zotsatirazi:
- kulimbikitsa kapena kufooka kwa cholingacho;
- kukula kwa zovuta zowopsa, zotsatira zoyipa.
Popanda kukaonana ndi dokotala, sikulimbikitsidwa kugwiritsa ntchito mankhwalawa m'njira zina.
Popanda kukaonana ndi dokotala, sikulimbikitsidwa kugwiritsa ntchito mankhwalawa m'njira zina.
Kuphatikiza kophatikizidwa
Ntchito yosakanikirana ndi maantibayotiki ndizoletsedwa. Mankhwala amateteza zochita za wina ndi mnzake, zimalepheretsa chitetezo cha m'thupi.
Zosiyanasiyana zimayambitsa kuphatikiza ndi diclofenac, ibuprofen, digoxin chifukwa cha kuchuluka kwa plasma.
Osagwiritsa ntchito limodzi ndi methotrexate. Kutalika kwa nthawi yayitali kumayambitsa chitukuko cha poizoni, imalepheretsa dongosolo la hematopoietic.
Kuphatikiza ndi zakumwa zoledzeretsa kumayambitsa chowonjezera. Kuwopseza mwachindunji kutuluka kwa magazi, ziwalo zingapo.
Osavomerezeka kuphatikiza
Pewani kugwiritsidwa ntchito limodzi ndi heparin, maanticoagulants ena, thrombolytics kuti muchepe magazi. Kugwiritsa ntchito ndi valproic acid kumafuna kusamala. Kuwonjezeka kwa zotsatira zoyipa pamatumbo am'mimba ndi hematopoietic dongosolo kumaonekera.
Kuphatikiza komwe kumafunikira kusamala
Akatengedwa, corticosteroids amachepetsa masilicylates m'thupi. Kuthana kwa mahomoni kumayambitsa zizindikiro zosokoneza bongo.
Musapitirire Mlingo wa odwala omwe akutenga insulin, pakamwa hypoglycemic. Kuopsa kopezeka ndi hypoglycemia kumafuna kuyang'aniridwa ndi achipatala mosalekeza.
Maantacid okhala ndi aluminiyamu ndi magnesium, amachepetsa mphamvu ya ma salicylates.
Kuyenderana ndi mowa
Zowonjezera zakumwa zoledzeretsa ndi salicylates zimawononga thupi, mosasamala za msinkhu komanso kuuma kwa matendawa.
Zowonjezera zakumwa zoledzeretsa ndi salicylates zimawononga thupi, mosasamala za msinkhu komanso kuuma kwa matendawa.
Kuphatikiza kowopsa kumapangidwa, kuwonetseredwa ndi zovuta zoyipa. Kutulutsa magazi kwambiri kumayamba, ntchito ya chiwindi imachepa, zimachitika kwambiri mu mitsempha. Izi zimapangitsa kukhala kosatheka kumwa mankhwalawo ndi mowa limodzi.
Analogi
Mulinso ndi zomwe zimagwira. Nthawi zambiri amagwiritsidwa ntchito:
- Taspir;
- CardiASK;
- Thromboass;
- Acecardol;
Thrombo ACC ndi analogue of aspiric.
Pakati pazofanizira zakunja, mumakonda kugwiritsa ntchito Trombogard 100, Trombopol, Upsarin UPSA. Kusankha kwa mankhwalawa kuyenera kuchitidwa ndi dokotala.
Kupita kwina mankhwala
Kodi ndingagule popanda kulandira mankhwala?
Zimapezeka pa malonda aulere.
Mtengo wa Aspicore
Mapaketi a mapiritsi 30 amapezeka ku ma ruble 63. Phukusi lomwe lili ndi mapiritsi 90, mtengo wake umachokera ku ma ruble 105.
Zosungidwa zamankhwala
Sungani pamalo otetezedwa ku kuwala ndi chinyezi. Kutentha kosasamala kuposa + 25̊ С. Pewani patali ndi ana.
Tsiku lotha ntchito
Moyo wa alumali - mpaka zaka 2. Zawonetsedwa pamaphukusi. Osagwiritsa ntchito tsiku litatchulidwa.
Wopanga
Vertex CJSC, Russia.
Ndemanga za Aspicore
Inna, wazaka 56, Belgorod
Panali mavuto ndi mtima, kuchuluka kowonjezereka. Anamwa mankhwalawo pamalangizo a dokotala wamtima wazaka ziwiri. Mankhwala amapezeka momasuka, mtengo wake ndi wokwanira. Ndimamva bwino.
Natalya, wazaka 27, Kharkov
Mwamuna wanga ali ndi matenda ashuga. Dotolo adayika mapiritsi otetezedwa mchimake. Popewa, mulingo woyenera, umatenga 200 mg tsiku lililonse. Palibe zoyipa zomwe zimachitika. Mkhalidwewo ndiwokhutiritsa.
Alina, wazaka 40, Russia
Mankhwala amathandizira pakhungu lamavuto. Zokhudza ukhondo wa khungu la nkhope, ndimapanga masks, omwe ndi gawo. Zimakupatsani mwayi wokhala ndi khungu labwino.
