Gliclazide canon ndi mankhwala omwe ali ndi vuto la hypoglycemic. Ndi iyo, mutha kusintha magawo a glucose, magawo a hematological ndi kayendedwe ka magazi. Kuphatikiza apo, mankhwalawa ali ndi phindu pakubwera kwa magazi ndi hemostasis, amagwiritsidwa ntchito popewa micothrombosis komanso njira zotupa m'makoma a microvessels.
Dzinalo Losayenerana
Mankhwala a INN: Gliclazide.
Gliclazide canon ndi mankhwala omwe ali ndi vuto la hypoglycemic.
Ath
A10VB09.
Kutulutsa mafomu ndi kapangidwe kake
Mankhwala amapezeka mu mawonekedwe a mapiritsi, omwe amadziwika ndi kumasulidwa kosasunthika. Wopanga amapereka ma 2 Mlingo: 30 mg ndi 60 mg. Mapiritsiwo ali ndi mawonekedwe ozungulira a biconvex ndi mtundu woyera. Zomwe zikuchokera mankhwalawa zimaphatikizapo:
- yogwira mankhwala (gliclazide);
- zosakaniza zowonjezera: colloidal silicon dioxide, ma cellcose a cellulose, magnesium stearate (E572), hydroxypropyl methylcellulose, mannitol, mafuta a masamba a hydrogenated.
Mankhwala amapezeka mu mawonekedwe a mapiritsi, omwe amadziwika ndi kumasulidwa kosasunthika.
Zotsatira za pharmacological
Mfundo za mankhwalawa zimakhudzidwa ndimomwe zimakhudzira ma cell a beta a kapamba. Chifukwa chakuchita kwa ma cell, ma membrane am'mimba amasungunuka ndipo njira za KatiF zimatsekedwa. Izi zimabweretsa kutsegulidwa kwa njira za calcium ndi kulowa kwa calcium ion m'maselo a beta.
Zotsatira zake ndikuwamasulidwa ndikuwonjezereka kwa insulin, komanso kayendedwe kazinthu zoyenda mozungulira.
Mphamvu ya mankhwalawa ikupitirirabe mpaka ndalama zomwe amapanga insulin zikatha. Chifukwa chake, ndimankhwala omwe amapezeka nthawi yayitali ndi mapiritsi awa, insulin synthesis imachepetsedwa. Koma mankhwala atatha, ma cell a beta amabwerera mwabwinobwino. Popanda kuyankhidwa kwachithandizo, ndibwino kukaonana ndi dokotala nthawi yomweyo.
Mfundo za mankhwalawa zimakhudzidwa ndimomwe zimakhudzira ma cell a beta a kapamba.
Pharmacokinetics
Mankhwalawa amakamwa m'mimba. Pogwiritsa ntchito nthawi yomweyo chakudya chake, mayamwidwe ake amachepa.
The achire zotsatira zimawonedwa pambuyo maola 2-3. Pazitali kwambiri pazogwira ntchito m'madzi a m'magazi zimawonedwa pambuyo pa maola 6-9. Kutalika kwakanthawi - 1 patadutsa pakamwa. Mankhwalawa amachotseredwa m'mimba ndi impso.
Zizindikiro zogwiritsidwa ntchito
Mapiritsi amayikidwa zochizira matenda osagwirizana ndi insulin omwe amadalira shuga (mtundu 2), ngati zakudya, kuchuluka kwa kulemera ndi masewera olimbitsa thupi sizikuthandizira pazinthu zabwino. Kuphatikiza apo, mankhwalawa amagwiritsidwa ntchito popewa zovuta za kunenepa kwambiri, mtundu wachiwiri wa matenda ashuga komanso chithandizo cha matenda omaliza.
Mapiritsi amalembedwa kuti athandizire odwala omwe samadwala matenda a shuga.
Contraindication
Kugwiritsa ntchito mankhwala kumaphatikizidwa motere:
- mawonekedwe a insulin omwe amadalira shuga (mtundu 1);
- zaka zosakwana 18;
- mkaka wa m`mawere ndi pakati;
- kwambiri aimpso ndi kwa chiwindi kuwonongeka;
- chikomokere;
- matenda a shuga a ketoacidosis;
- IF (hypersensitivity) kuti sulfonamides ndi zotumphukira za sulfanylurea;
- tsankho limodzi ndi zigawo zikuluzikulu za mankhwala.
Ndi chisamaliro
Mankhwalawa angagwiritsidwe ntchito poyenda pang'ono komanso pang'ono pa kuwonongeka kwa impso ndi chiwindi. Mankhwalawa amadziwitsidwa mosamala mu zotsatirazi zamikhalidwe ndi mikhalidwe:
- kusasamala kapena kudwala;
- matenda a endocrine;
- matenda oopsa a CVS;
- shuga-6-phosphate dehydrogenase akusowa;
- uchidakwa;
- odwala okalamba (azaka 65 ndi akulu).
Momwe mungatenge Glyclazide Canon?
Mankhwala othandizira pakamwa amapangidwira odwala okhawo. Mlingo wamba wa tsiku lililonse umachokera ku 30 mpaka 120 mg. Mlingo weniweni umatsimikiziridwa ndi katswiri potengera chithunzi cha chipatala.
Mlingo wa tsiku lililonse umalimbikitsidwa kuti umwenso 1 pakumwa piritsi limodzi. Popewa kugwiritsidwa ntchito kosafunikira, ndibwino kumwa mankhwalawa kwa mphindi 30 mpaka 40 musanadye.
Popewa kugwiritsidwa ntchito kosafunikira, ndibwino kumwa mankhwalawa kwa mphindi 30 mpaka 40 musanadye.
Chithandizo ndi kupewa matenda ashuga
Mlingo woyambirira wa mankhwalawa pochiza matenda osokoneza bongo omwe amadalira insulin komanso kugwiritsa ntchito sulfonylurea sayenera kupitirira 75-80 g Pazifukwa zodzitetezera, mankhwalawa amagwiritsidwa ntchito pa 30-60 mg / tsiku. Potere, adotolo amayenera kuwunika mosamala odwala 2 mawola atatha kudya komanso pamimba yopanda kanthu. Ngatiapezeka kuti mankhwalawo sanachite bwino, ndiye kuti amawonjezeka masiku angapo.
Zotsatira zoyipa
Mankhwalawa amatha kuzungulira thupi. Komabe, kugwiritsa ntchito mankhwalawa kwa nthawi yayitali, odwala amatha kukumana ndi zovuta.
Pazifukwa zodzitetezera, mankhwalawa amagwiritsidwa ntchito pa 30-60 mg / tsiku.
Matumbo
- kutsegula m'mimba kapena kudzimbidwa;
- kufuna kusanza;
- nseru
- kupweteka kwam'mimba komanso kusasangalala.
Hematopoietic ziwalo
- kuchepa magazi (kusintha);
- leukopenia;
- agranulocytosis;
- thrombocytopenia (nthawi zina).
Pa khungu
- Khungu;
- zotupa
- kutsekeka kwa khungu;
- kutupa kwa nkhope ndi miyendo.
Kuchokera pamtima
- kuchuluka kwa mtima (kuphatikizapo tachycardia);
- kuchuluka kwa kuthamanga kwa magazi;
- kugwedezeka.
Pa mbali ya chiwindi ndi biliary thirakiti
- hepatitis;
- cholestatic jaundice.
Pa mbali ya ziwalo zamasomphenya
- kutayika kwa chidziwitso;
- kuchuluka kwachulukidwe ka intraocular.
Malangizo apadera
Mankhwalawa amagwiritsidwa ntchito limodzi ndi zakudya zamafuta ochepa.
Mukamamwa, wodwala amayenera kuyang'anira kuchuluka kwa shuga m'magazi.
Mukamamwa mankhwalawa, wodwala amayenera kuyang'anira kuchuluka kwa shuga m'magazi.
Mu matenda a shuga mellitus mu gawo lowonongeka kapena pambuyo pachitetezo cha opaleshoni, mwayi wogwiritsa ntchito insulin uyenera kuganiziridwanso.
Kuyenderana ndi mowa
Ndi zoletsedwa kumwa mowa pa mankhwalawa.
Zokhudza mphamvu pakuwongolera njira
Chifukwa cha chiwopsezo cha hypoglycemia mwa odwala omwe amamwa mapiritsiwa, muyenera kusiyiratu ntchito zomwe zingakhale zoopsa ndikuyendetsa galimoto.
Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere
Malangizo ogwiritsira ntchito mankhwalawa amaletsa kuti azimayi azimwedwa ndi nthawi yoyamwitsa.
Chifukwa cha chiwopsezo cha hypoglycemia mwa odwala omwe amamwa mapiritsiwa, muyenera kusiyiratu ntchito zomwe zingakhale zoopsa ndikuyendetsa galimoto.
Kupangira Gliclazide Canon ya Ana
Mankhwala ndi oletsedwa kugwiritsidwa ntchito ndi ana aang'ono.
Gwiritsani ntchito mu ukalamba
Odwala okalamba amaloledwa kugwiritsa ntchito mankhwalawa mosamala kwambiri komanso moyang'aniridwa ndi achipatala.
The ntchito aimpso kuwonongeka
Sizoletsedwa kugwiritsa ntchito mapiritsiwa ndi hypoglycemic athari ndi a kwambiri aimpso. Mlingo amasankhidwa payekha malinga ndi odwala omwe ali ndi vuto laimpso.
Gwiritsani ntchito ntchito yolakwika ya chiwindi
Ndi osafunika kugwiritsa ntchito mankhwalawa pachimake komanso matenda a chiwindi.
Ndi osafunika kugwiritsa ntchito mankhwalawa pachimake komanso matenda a chiwindi.
Bongo
Kuchulukitsa mlingo wa mankhwalawa kungayambitse hypoglycemia. Zizindikiro zolimbitsa thupi (zopanda mawonekedwe am'mitsempha komanso kusazindikira) zimapangidwa modabwitsa pogwiritsa ntchito chakudya komanso kusintha zakudya ndi mlingo wa mankhwalawo.
Woopsa milandu, pali chiopsezo cha hypoglycemic zimachitika, zomwe zimayendera limodzi ndi kupweteka, chikomokere ndi zovuta zina zamitsempha. Wovutitsidwa pankhaniyi amafuna kuchipatala mwachangu.
Njira zoyendetsera thupi sizothandiza chifukwa cha kuphatikiza kwa mapiritsi omwe amapezeka ndi mapuloteni a plasma.
Kuchita ndi mankhwala ena
Pogwiritsa ntchito nthawi yomweyo mankhwala ndi mankhwala ena, mutha kukumana ndi mayankho abwino komanso olakwika. Ngati zizindikiro zoyipa zikuwoneka, pitani kuchipatala.
Kuphatikiza kophatikizidwa
Sizoletsedwa kugwiritsa ntchito nthawi imodzi ndi miconazole, chifukwa zimawonjezera mphamvu ya hypoglycemic. Kuphatikiza apo, phenylbutazone sayenera kuperekedwa nthawi yomweyo ndi mankhwalawa.
Phenylbutazone sayenera kutumikiridwa pamodzi ndi Glyclazide Canon.
Osavomerezeka kuphatikiza
Ndiosafunika kugwiritsa ntchito mankhwala okhala ndi ethanol ndi mankhwala omwe amapangidwa ndi chlorpromazine nthawi imodzi ndi mankhwala omwe mukufunsidwa.
Phenylbutazone, Danazole ndi mowa zimawonjezera hypoglycemic zotsatira za mankhwala. Pankhaniyi, ndikwabwino kusankha mtundu wina wa anti-kutupa.
Kuphatikiza komwe kumafunikira kusamala
Kuphatikiza kwa mankhwalawa ndi Acarbose, beta-blockers, biguanides, Insulin, Enalapril, Captopril ndi mankhwala ena a anti-yotupa omwe si a antiidal komanso mankhwala omwe ali ndi chlorpromazine amafunika chisamaliro chapadera, chifukwa munthawi imeneyi mumakhala chiopsezo cha hypoglycemia.
Analogi
Pankhani ya contraindication kapena kusapezeka kwa mankhwala, imodzi mwa mayanjano ake ingagulidwe:
- Glycaside MV;
- Diabetes;
- Osiklid et al.
Kupita kwina mankhwala
Mankhwala omwe mumalandira.
Kodi ndingagule popanda kulandira mankhwala?
Ndizosatheka kugula mankhwala popanda kulandira mankhwala.
Ndizosatheka kugula mankhwala popanda kulandira mankhwala.
Mtengo wa Glyclazide Canon
Mtengo wa mankhwalawa m'mafakitale aku Russia umasiyana ndi ma ruble 110-150 pakiti iliyonse ya mapiritsi 60.
Zosungidwa zamankhwala
Mankhwalawa amasungidwa m'malo amdima, owuma komanso osatheka kuwapeza kwa nyama ndi ana. Kutentha - osati kuposa + 25 ° C.
Tsiku lotha ntchito
Osapitilira zaka ziwiri mutapanga.
Wopanga
Kampani yopanga mankhwala ku Russia Canonfarm Production.
Ndemanga pa Gliclazide Canon
Pazinthu zapadera za intaneti, mankhwalawa nthawi zambiri amayankhidwa. Ndemanga zoyipa zimagwirizanitsidwa ndi kusatsatira malangizo azachipatala.
Madokotala
Sergey Shabarov (wochiritsa), wazaka 45, Volgodonsk.
Mankhwala abwino ngati agwiritsidwa ntchito mwanzeru. Mlingo umasankhidwa mophweka - 1 nthawi patsiku (pafupifupi). Mlingo wa shuga umayendetsa bwino. Kuphatikiza apo, mankhwalawa ali ndi phindu pa ntchito yozungulira komanso amachepetsa chiopsezo cha zovuta za matenda ashuga.
Anna Svetlova (wochiritsa), wazaka 50, Moscow.
Odwala amakhutira ndikamawalembera mapiritsi. Sindinakumane ndi zovuta zapadera zilizonse. Chimodzi mwazabwino za mankhwala ndimtengo wotsika mtengo. Ndipo kugwira ntchito kwake kulinso pamwambapa!
Anthu odwala matenda ashuga
Arkady Smirnov, wazaka 46, Voronezh.
Akadapanda mapiritsi awa, ndiye kuti manja anga akadatsika kalekale. Ndakhala ndikudwala matenda ashuga a 2 kwa nthawi yayitali. Mankhwalawa amawongolera bwino magazi. Zotsatira zoyipa, ndimakumana ndi mseru wokha, koma adadzipatula pambuyo masiku angapo.
Inga Klimova, wazaka 42, Lipetsk.
Mayi anga ali ndi matenda osokoneza bongo omwe amadalira insulin. Adotolo adamupatsa mapiritsiwo. Tsopano adayamba kukhala wokondwa komanso analawa moyo.
