Actovegin - mankhwala omwe amathandizira kukhazikika kwa kagayidwe kazakudya mu minofu ndimitsempha yamagazi, amathandizanso kukonzanso.
Dzinalo Losayenerana
Sichoncho.
Dzina lazamalonda ndi Actovegin®. Mu Chilatini - Actovegin.
Ampoules ndi madzi owoneka bwino kapena achikasu pang'ono pobayira.
ATX
B06AB (Zinthu zina zamagazi)
Kutulutsa mafomu ndi kapangidwe kake
Ampoules ndi madzi owoneka bwino kapena achikasu pang'ono pobayira.
Yogwira pophika: amachepetsa hemoderivative, 40 mg / ml.
Yopangidwa ndi dialysis, kupatukana kwa nembanemba komanso kupatula magawo a magazi a nyama zazing'ono, odyetsedwa mkaka wokha.
Chowonjezera: madzi a jakisoni.
Itha kupangidwa ndi makampani opanga mankhwala Takeda Austria GmbH (Austria) kapena Takeda Pharmaceuticals LLC (RF). Atakulungidwa mu 2 ml, 5 kapena 10 ml mu galasi lopanda utoto la 5 ma PC. mumapangidwe okhala ndi pulasitiki opangidwa ndi pulasitiki. Maselo okhala ndi 1, 2 kapena 5 m'makatoni.
Mankhwala ndi a gulu la antihypoxants.
Pa paketi iliyonse yamakhadi pazikhala ndi zomata zozungulira zomwe zilembedwe za holographic ndikuwongolera kutsegulira koyamba.
Zotsatira za pharmacological
Ili m'gulu la antihypoxants. Nthawi yomweyo ili ndi mitundu itatu ya zotsatira:
- neuroprotective (imalepheretsa kufa kwa maselo aubongo - ma neurons - chifukwa cha zotsatira zoyipa za njira zosafunikira zamkati kapena zikoka zakunja);
- metabolic (imalimbikitsa kapangidwe ka adenosine triphosphate (ATP) ndikuwonjezera mphamvu yama cell);
- microcirculatory (kayendedwe kabwinobwino kazinthu zachilengedwe m'thupi ndi ziwiya za thupi).
Zimathandizira kukonza chimbudzi ndi kukonza oxygen ndi glucose.
Imasokoneza mapangidwe a njira za apoptotic zomwe zimapangidwa ndi beta-amyloid (Aβ25-35). Imasanduliza mphamvu ya zida za nyukiliya kappa B (NF-kB), yomwe imakhala chofunikira kwambiri pakulimbikitsidwa kwamkati mwa chapakati ndi cham'mitsempha cham'mitsempha cham'mimba komanso apoptosis.
Imagwira bwino ma microcirculation komanso kutsika kwa magazi mu ma capillaries, kumachepetsa kuyang'ana kwa pericapillary zone ndi diastolic. Zimatsimikizirika kuti mphamvu ya mankhwalawa imawonedwa patatha mphindi 30, ndipo mphamvu yake itadutsa patatha maola atatu mutatsata.
Actovegin imathandizira pakachulukidwe ka magazi ndi kuthamanga kwa magazi mu ma capillaries.
Pharmacokinetics
Popeza mankhwalawa ali ndi ziwalo zolimbitsa thupi zomwe zilipo kale mthupi, mankhwala ake a pharmacokinetic molingana ndi magawo a labotale sangaphunzire.
Zomwe zimayikidwa
Actovegin 40 imaphatikizidwa mu mitundu yovuta ya chithandizo:
- zovuta zamavuto osiyanasiyana etiologies;
- zotumphukira mtima dysfunctions ndi ngozi cerebrovascular;
- zotumphukira angiopathy;
- matenda a shuga;
- kusinthika kwa minofu (kuvulala, maopareshoni, zilonda zam'mimba za m'munsi, etc.);
- Zotsatira za mankhwala a radiation.
Kuphatikiza apo, ndi mawonekedwe awa, mankhwalawa am'mimba, zilonda zam'mimba ndi duodenum amathandizidwa.
Contraindication
Sichikulimbikitsidwa kuti chiwopseze kwambiri ku zigawo za mankhwala, mtima wosakhazikika, edema mu bronchopulmonary system, oliguria, anuria ndi congestive process mu thupi.
Ndi chisamaliro
Pamaso pa hyperchloremia ndi hypernatremia, muubwana.
Momwe mungatenge Actovegin 40
Kutalika, Mlingo ndi mitundu ya mankhwala imatsimikizika potengera zomwe zimayambitsa matenda. Zimatsimikiziridwa payekhapayekha. Amawerengera kudzera m'mitsempha, intravenly ndi intramuscularly.
Mankhwalawa metabolism ndi zotupa zam'mimba mu ubongo, pazigawo zoyambirira zamankhwala, 10-20 ml ya iv kapena iv amalowetsedwa tsiku lililonse. Kenako, malinga ndi dongosolo la mankhwalawo, 5 ml iv kapena IM ndi kuchepetsedwa kulowetsedwa.
Mu ischemic stroke mu pachimake siteji, mankhwala amathandizidwa.
Mu ischemic stroke mu pachimake siteji, infusions amachitidwa. Pachifukwa ichi, mankhwala (10-50 ml) amawonjezeredwa ku 200-300 ml ya kapangidwe ka isotonic (5% glucose kapena sodium chloride solution). Zitatha izi, mankhwalawa amasinthidwa kukhala piritsi la mankhwalawo.
Zochizira pazinthu zomwe zimachitika chifukwa cha kusokonezeka kwa minyewa yaubongo, mankhwalawa amadziwikiridwa ndi iv kapena iv (20-30 ml ya mankhwalawa amaphatikizidwa ndi 200 ml ya kapangidwe ka isotonic).
Kuti athetse zizindikiro za matenda ashuga a polyneuropathy, 50 ml ya iv ndi kulowetsedwa. Kenako achire zotsatira kusintha kwa Actovegin mapiritsi.
Ndi makonzedwe a / m, mpaka 5 ml amagwiritsidwa ntchito. Lowani pang'onopang'ono.
Kumwa mankhwala a shuga
Amatengera mankhwala omwe amathandizira kuti metabolism ikhale yachilendo. Chifukwa chake, ndizovomerezeka pakuchipatala.
Mankhwalawa amafunikira pakuchiza kwa matenda a shuga.
Zotsatira zoyipa
Imalekeredwa bwino. Nthawi zina, mavuto amayamba.
Kuchokera ku minculoskeletal system
Myalgia (kawirikawiri).
Kuchokera ku chitetezo chamthupi
Thupi lawo siligwirizana mu mawonekedwe a matenda mawonekedwe a kutentha thupi kapena anaphylactic mantha.
Pa khungu
Kutupa, totupa, kapena redness.
Matupi omaliza
Kukhalapo kwa matembenuzidwe akuwonetseredwa kwa matupi awo kuyenera kudziwitsidwa kwa dokotala.
Zotsatira zoyipa za mankhwalawa zimatha kukhala zosagwirizana.
Malangizo apadera
Chifukwa cha chiwopsezo cha anaphylactic pakugwiritsa ntchito koyamba, kuyezetsa magazi kwa mankhwalawa kuyenera kuchitidwa musanayambike.
M'magulu osiyanasiyana, mankhwalawa amatha kukhala ndi mtundu wina. Koma izi sizikhudza kulekerera kwa mankhwalawa ndi ntchito zake.
Ma ampoules otseguka samasungira. Iyenera kugwiritsidwa ntchito nthawi yomweyo.
Kuyenderana ndi mowa
Mukamamwa mowa samataya mankhwala.
Zokhudza mphamvu pakuwongolera njira
Palibe zambiri zomwe zilipo.
Mukamamwa mowa samataya mankhwala.
Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere
Zotsatira zoyipa zomwe zimachitika pa mayi kapena mwana wosabadwayo sizinawoneke.
Kusankhidwa Actovegin ana 40
Kutumizidwa kwa makanda okhala ndi zizindikiro za hypoxia. Kuphatikiza apo, mankhwalawa amaperekedwa kwa ana obadwa ndipo amatengera kuvulala kwaubongo.
Gwiritsani ntchito mu ukalamba
Amagwiritsidwa ntchito pochiza komanso kupewa hypoxic komanso vuto la ischemic la ziwalo ndi minyewa mwa odwala okalamba.
Bongo
Panalibe milandu ya overto wa Actovegin.
Amagwiritsidwa ntchito pochiza komanso kupewa hypoxic komanso vuto la ischemic la ziwalo ndi minyewa mwa odwala okalamba.
Pali kuthekera kowonjezereka kuwonekera kwa zoyipa.
Kuchita ndi mankhwala ena
Palibe zotsatira zoyipa chifukwa chogwiritsa ntchito mankhwala omwe adapezeka.
Zimagwirizana ndi mitundu ya mankhwala omwe amagwiritsidwa ntchito popanga zovuta za ischemic stroke (mwachitsanzo, ndi Mildronate).
Kuphatikiza apo, imagwiritsidwa ntchito pophatikizira ndi mankhwala omwe amagwiritsidwa ntchito kuti athetse kuperewera kwa venous ndi placental, mankhwalawa a thrombosis (mwachitsanzo, ndi Curantyl).
Kuphatikiza komwe kumafunikira kusamala
Kuphatikizidwa ndi ACE inhibitors (Enalapril, Lisinopril, Captopril, etc.), komanso kukonzekera kwa potaziyamu, kumafunikira kusamala.
Analogi
M'malo a Actovegin ndi:
- Vero-Trimetazidine;
- Curantyl-25;
- Cortexin;
- Cerebrolysin, etc.
Curantil-25 ndi analogue ya Actovegin.
Kupita kwina mankhwala
Ndi mankhwala.
Kodi ndingagule popanda kulandira mankhwala?
Mankhwala ambiri opezeka pa intaneti ali okonzeka kugulitsa osagwiritsa ntchito mankhwala.
Mtengo Actovegin 40
Mtengo wapakati umatengera kuchuluka kwa ma ampoules ndi kuchuluka kwawo phukusi. Chifukwa, mwachitsanzo, ku Russia, mtengo wa Actovegin (jekeseni wa 40 mg / ml ampoules a 5 ml 5 pcs.) Amasiyana kuchokera ma ruble 580 mpaka 700.
Ku Ukraine, phukusi lofananalo limawononga pafupifupi 310-370 UAH.
Mtengo wapakati wa mankhwalawa umatengera kuchuluka kwa ma ampoules ndi kuchuluka kwawo phukusi.
Zosungidwa zamankhwala
Pamalo otetezedwa ndi kuwala kwa dzuwa pa kutentha mpaka 25 ° C. Bisani ana.
Tsiku lotha ntchito
Zaka 3 kuyambira tsiku lopangira.
Wopanga
Nycomed Austria GmbH, Austria.
Wonyamula / Wowongolera kuyendetsa bwino: Takeda Pharmaceuticals LLC (Russia).
Ndemanga za madotolo ndi odwala pa Actovegin 40
Malingaliro a madokotala ndi odwala okhudzana ndi kugwiritsa ntchito, magwiridwe antchito ndi chitetezo amasiyana.
Vasilieva E.V., katswiri wamitsempha, Krasnodar
Actovegin alibe zotsatira zoyipa ndipo amalekeredwa bwino. Itha kugwiritsidwa ntchito onse mu monotherapy komanso mu regimens zovuta. Amasankhidwa kuti a pathologies a mtima dongosolo ndi metabolic zolephera. Ndikupangira odwala anga ambiri.
Marina, wazaka 24, Kursk
Anapereka jakisoni ndi ma donsi panthawi yoyembekezera kuti magazi azituluka. Palibe zoyipa. Pambuyo pa chithandizo, magazi amatuluka kukhala abwinobwino, ndipo kutopa ndi chizungulireko zidatha limodzi ndi matendawa. Ndimalangiza azimayi onse oyembekezera.
Nefedov I.B., wazaka 47, Oryol
Ngakhale kuti mankhwalawa aletsedwa ndi FDA (US Department of Health and Human Services), imagwiritsidwa ntchito kwambiri ku Russia ndi mayiko a CIS. Antigen wakunja. Sindikhulupirira mankhwalawa, malangizo omwe amawonetsa kuti ndizosatheka kuwunika malo ake a pharmacokinetic.
Afanasyev P.F. dokotala wa ultrasound, St.
Mankhwala abwino a antihypoxic omwe amasunga achire kwa miyezi 3-6. Chida ichi chimagwiritsidwa ntchito kwambiri kuchipatala chathu ku Research Institute. Ankylosing spondylitis yochotsa zizindikiro za matenda amisempha komanso matenda am'mimba otupa. Zimathandizira kuthetsa kupweteka kwa mutu, migraines, kumverera kwa nkhawa, kumapangitsa ntchito zamaganizidwe, etc.
