Lozap Plus - mankhwala ochepetsa kupanikizika kukhala mulingo wabwinobwino. Chifukwa cha mankhwalawa, katundu pamtima amachepa, chifukwa chake, chiwopsezo cha kusokonezeka m'melocardium chimachepa.
ATX
Khodi ya ATX ndi C09DA01.
Lozap Plus - mankhwala ochepetsa kupanikizika kukhala mulingo wabwinobwino.
Kutulutsa mafomu ndi kapangidwe kake
Zomwe zimagwira ndi 12.5 mg ya hydrochlorothiazide ndi 50 mg ya losartan potaziyamu. Zofunikira za chikhalidwe chothandizira ndi:
- simethicone emulsion;
- croscarmellose sodium;
- Utoto wofiirira;
- MCC;
- utoto wa quiniline wachikasu;
- hypromellose;
- mannitol;
- titanium dioxide;
- macrogol;
- magnesium wakuba.
Tulutsani mankhwalawa monga mapiritsi ndi utoto wa film.
Tulutsani mankhwalawa monga mapiritsi ndi utoto wa film.
Zotsatira za pharmacological
Hydrochlorothiazide ndi diuretic, ndipo potaziyamu losartan ndi angiotensin II receptor blocker. Chifukwa cha kupezeka kwa zinthu izi, mankhwalawa ali ndi zotsatirazi:
- kutsitsa magazi;
- amachepetsa ndende ya potaziyamu m'madzi am'magazi;
- imakhala ndi uricosuric.
Pharmacokinetics
Hydrochlorothiazide siikutulutsa mkaka ndipo siyidutsa chotchinga bongo. Komabe, thunthu limatha kulowa m'magazi a fetoplacental. Choikacho chimapukutidwa ndi impso. Sizinapikisidwe.
Mankhwalawa amachepetsa kuchuluka kwa potaziyamu m'madzi a m'magazi.
Pakupanga kagayidwe, losartan imakhala metabolite, yomwe 99% imakhala ndi mapuloteni amwazi. Kuzindikira kwakukulu kumachitika pambuyo pa maola atatu. Katunduyo amatengeka mwachangu.
Zizindikiro za Lozap kuphatikiza
Mankhwalawa adagwiritsidwa ntchito pazinthu zotsatirazi:
- Kuchepetsa chiopsezo cha matenda amitsempha yama mtima kutsutsana ndi maziko amanzere am'mitsempha yamagazi;
- ndi ochepa matenda oopsa;
- Kuchepetsa mwayi wokhala ndi vuto la mtima kapena sitiroko.
Contraindication
Contraindication imaperekedwa ndi zinthu zotsatirazi:
- kuwonongeka kwambiri kwa impso;
- gout
- mtundu wotsutsa wa hyperkalemia;
- kuchepa kwamkaka wa bile mu duodenum;
- zotupa zotsekemera zomwe zimakhudza khunyu;
- kukhudzika kwakukulu pazinthu zomwe zili pakapangidwe kamankhwala;
- Anuria
- kuvulala kwamphamvu kwa chiwindi;
- Refractory kuchepetsa kuchuluka kwa sodium ndi potaziyamu.
Kuphatikiza apo, sikulimbikitsidwa kugwiritsa ntchito zomwe akazi omwe akukonzekera kukhala ndi mwana.
Ndi chisamaliro
Matenda ndi zovuta zotsatirazi zimafuna kusamala:
- hyponatremia;
- kulephera kwa mtima;
- aimpso mtsempha wamagazi stenosis;
- magazi ochepa magnesium;
- mtima wowononga;
- matenda a zolumikizana minofu;
- Hyperkalemia
- mphumu, kuphatikiza mu anamnesis;
- mtundu woyamba wopanga kuchuluka kwa aldosterone;
- mitral kapena aortic stenosis;
- matenda amisala.
Momwe angatenge
Zomwe mungagwiritse ntchito mankhwalawa zimatengera zolinga ndi matendawo:
- Kuchepetsa chiopsezo cha matenda a mtima, kuyamba ndi piritsi 1 patsiku, ngati kuli kotheka, bweretsani mapiritsi 2 mapiritsi.
- Ndi kuthamanga kwa magazi - 1 nthawi patsiku. Ngati palibe zotsatira zomwe mukufuna, ndiye kuti mlingowo ungathe kuchuluka.
Mlingo weniweni umasankhidwa ndi adotolo, choncho onetsetsani kuti mwakumana ndi katswiri musanayambe chithandizo.
Kugwiritsa ntchito kwayokha sikudalira chakudya.
Kodi Lozap kuphatikiza amakakamizidwa ndi mavuto otani?
Mankhwalawa amangoikidwa ndi kuthamanga kwa magazi.
Mankhwalawa amangoikidwa ndi kuthamanga kwa magazi.
M'mawa kapena madzulo
Ndikulimbikitsidwa kumwa mankhwalawa m'mawa. Ngati ndi kotheka, mankhwalawa amagwiritsidwa ntchito kawiri pa tsiku - mutadzuka ndi madzulo.
Kodi ndizotheka kumwa mankhwalawa chifukwa cha matenda ashuga
Mankhwalawa amatengedwa pokhapokha ndi chilolezo cha dokotala, chifukwa mankhwalawo amathandizira kulolerana kwa shuga.
Zotsatira zoyipa
Mukamaganizira za kuthekera kosavomerezeka.
Matumbo
Mkhalidwe umadziwika ndi zizindikiro:
- kusanza
- kamwa yowuma
- nseru
- cramping;
- kudzimbidwa
- zizindikiro za dyspeptic;
- chisangalalo;
- kapamba
- gastritis;
- kutukusira kwa tiziwalo tating'onoting'ono.
Hematopoietic ziwalo
Pali zizindikiro zoyipa:
- kuchepa magazi, kuphatikizapo mtundu wa hemolytic ndi aplastic;
- leukopenia;
- thrombocytopenia;
- agranulocytosis.
Pakati mantha dongosolo
Kuchokera kumbali ya dongosolo lamanjenje lamkati pali zizindikiro:
- zotumphukira neuropathy;
- chisokonezo cha chikumbumtima;
- kusowa tulo
- kuchuluka kukwiya;
- vuto kugona;
- mantha;
- kugwedezeka
- zolota;
- Kuda nkhawa
- migraine
- kukomoka.
Kuchokera kwamikodzo
Wodwala ali ndi zizindikiro zotsatirazi:
- kuchuluka kwa usiku kusiyirana masana masana;
- kukakamiza pafupipafupi kuchotsa chikhodzodzo;
- impso zolakwika;
- yotupa yomwe imakhudza kwamikodzo;
- kukhalapo kwa shuga mkodzo.
Kuchokera ku kupuma
Pazovuta, mawonekedwe amawonekera:
- pulmonary edema ya sanali-cardiogenic;
- kugonjetsedwa kwa mphuno za mphuno;
- kutsokomola
- kuchulukana kwammphuno;
- kusapeza bwino pakhosi;
- bronchitis;
- kutukusira kwa zimakhala za pharynx ndi mucous nembanemba za m'mimba.
Kuchokera ku chitetezo chamthupi
Wodwala akuwonekera:
- anaphylactic zimachitika;
- angioneurotic mtundu wa edema;
- kutentha thupi.
Kuchokera mumtima
Zowonongeka pamtima pazochitika zoyipa zimayambitsa kupangika kwa zizindikiro:
- michere yamitsempha yamagazi;
- kuchuluka kwa mtima;
- sinus mtundu bradycardia;
- kupweteka kwa sternum;
- orthostatic chikhalidwe cha ochepa hypotension.
Pa mbali ya chiwindi ndi biliary thirakiti
Zizindikiro zotsatirazi zoyipa zimadziwika ndi njira yothandizira matenda a chiwindi ndi chiwindi:
- cholecystitis;
- cholestatic jaundice;
- kulakwitsa kwa chiwindi ntchito.
Kuchokera minofu ndi mafupa
Wodwala ali ndi mawonekedwe awa:
- kusapeza bwino mu minofu ndi mafupa;
- kukokana
- fibromyalgia;
- kutupa
- kupweteka kumbuyo ndi mafupa: m'chiuno, phewa ndi bondo;
- nyamakazi.
Matupi omaliza
Chizindikiro chotsatira cha matupi awo sagwirizana ndi zotheka:
- malungo;
- kutupa
- kusasangalala mu mawonekedwe a kuyaka ndi kuyabwa;
- redness la pakhungu.
Malangizo apadera
Mankhwalawa sagwiritsidwe ntchito musanayesenso magwiridwe amtundu wa parathyroid, chifukwa mankhwalawa amatha kukhala ndi vuto pazotsatira zodziwira.
Kukhazikitsidwa kwa Lozap Plus kwa ana
Mankhwalawa amalephera kuchiza ana. Malangizowo akuwonetsa kuti odwala omwe ali ndi zaka zosakwana 18 sayesedwa mankhwala, chifukwa palibe kafukufuku omwe adachitika kuti adziwe chitetezo ndi mankhwalawa.
Mankhwalawa amalephera kuchiza ana.
Gwiritsani ntchito mu ukalamba
Pa mankhwala a odwala omwe ali ndi zaka zopitilira 65, palibe chifukwa chosinthira.
Mimba komanso kuyamwa
Kutenga mankhwalawa mu 1, 2nd ndi 3 trimesters wam'mimba kumabweretsa zotsatira zoyipa pakukula kwa mwana wosabadwayo, chifukwa chake, mankhwalawa sagwiritsidwa ntchito panthawi ya bere.
Kuti mupeze chithandizo mukamayamwa, muyenera kukana kuyamwitsa kapena kusankha mankhwala ena.
Kuyenderana ndi mowa
Kugwiritsa ntchito pamodzi kwa Lozap Plus ndi zinthu zokhala ndi mowa kumabweretsa zovuta. Kumwa mowa panthawi yamankhwala kumaletsedwa.
Zokhudza mphamvu pakuwongolera njira
M'pofunika kukana kuyendetsa galimoto chifukwa cha mankhwalawa pazomwe zimachitika komanso kuchuluka kwake.
M'pofunika kukana kuyendetsa galimoto chifukwa cha mankhwalawa pazomwe zimachitika komanso kuchuluka kwake.
Bongo
Zizindikiro za bongo:
- bradycardia;
- kusowa kwa ma elekitirodi;
- tachycardia;
- kuthamanga kwa magazi.
Ndi zizindikiro zotere, nthawi yomweyo amapita kuchipatala. Wodwalayo adapangidwa kuti apatsidwe mkaka wam'mimba ndi chithandizo chothandizira kuti athe kuwonetsa.
Kuchita ndi mankhwala ena
Mukamamwa hydrochlorothiazide, pali zinthu zotsatirazi zomwe zimachitika pakukhudzana ndi mankhwala:
- mankhwala ofewetsa thukuta ndi corticosteroids - chiwopsezo chowonjezereka cha kuchepa kwa electrolyte;
- Osiyanasiyana othandizira ayodini - mwayi wokhala ndi vuto la impso pakuchepa kwa madzi;
- Carbamazepine - amathandizira pakupezeka kwa hyponatremia;
- mtima glycosides - chiopsezo cha arrhythmias chikukula;
- Methyldopa - hemolytic anemia imatha;
- salicylates - kumawonjezera zovuta pa chapakati mantha dongosolo mukamagwiritsa hydrochlorothiazide ambiri;
- mankhwala a anticholinergic - bioavailability okodzetsa okhudzana ndi gulu la thiazide limawonjezeka;
- mankhwala omwe ali ndi lithiamu - poizoni amathandizidwa;
- antihypertensive othandizira - zowonjezera zimachitika.
Kukhalapo kwa losartan ku Lozap Plus kumayimiridwa ndi mikhalidwe yofananira yamankhwala:
- antipsychotic mankhwala ndi ma triceclic depressants - mwayi wa ochepa matenda oopsa umapangika;
- Aliskiren - imaphatikizidwa kwa odwala omwe ali ndi matenda osokoneza bongo motsutsana ndi maziko a kulephera kwambiri kapena kwapakati kwaimpso;
- NSAIDs - mphamvu ya Lozap imakula;
- diuretic mankhwala a potaziyamu oteteza mtundu - mwayi wowonjezera wa potaziyamu m'magazi ukuwonjezeka;
- Kashiamu D3 - ndikofunikira kuyang'anira kuchuluka kwa calcium mthupi la wodwalayo.
Wopanga
Chidacho chimamasulidwa ndi kampani yaku Czech mankhwala Zentiva.
Analogi
Mankhwala ofanana ndi awa:
- Lorista ndi mankhwala ogwiritsidwa ntchito ngati angiotensin 2 antagonist.
- Cozaar ndi mankhwala othandizira kuchepetsa magazi.
- Losartan ndiwotsika mtengo wogwiritsira ntchito mankhwala okwera mtengo. Chipangizocho chimachepetsa kuthamanga kwa magazi kunthawi zonse.
- Presartan ndi mankhwala a antihypertgency omwe amakhala olimbitsa magazi.
- Blocktran ndi mankhwala a ku Russia omwe amagwiritsidwa ntchito poletsa mtima komanso matenda oopsa.
Kupita kwina mankhwala
Amamasulidwa mosamalitsa malinga ndi zomwe wapatsidwa.
Mtengo wa Lozap Plus
Kugulitsa ndalama kumachitika pamtengo wa ma ruble 300-700.
Zosungidwa zamankhwala
Mankhwalawa amasungidwa m'malo owuma komanso amdima.
Tsiku lotha ntchito
Ndizoyenera zaka 2.
Lozap Plus ikupezeka pa mankhwala okha.
Ndemanga pa Lozap Plus
Omvera zamtima
Evgeny Mikhailovich
Kupezeka ndi mwayi wochepa wakutukuka ndizotsatira zazikulu za Lozap Plus. Mankhwalawa ali ndi vuto lochita kupsa mtima komanso kutulutsa mphamvu ya glucosuric. Komabe, kugwiritsa ntchito mankhwalawa nthawi zonse sikokwanira, kotero muyenera kuwonjezera ndalama momwe mulibe hydrochlorothiazide.
Vitaliy Konstantinovich
Kugwiritsa ntchito nthawi imodzimodziyo kwa hydrochlorothiazide ndi losartan ndi njira yabwino yosakanikirana ndi zinthu zomwe zimakhala zoyenera kwa odwala ambiri. Komabe, pamavuto opitilira 160 mm Hg. Art. pakufunika mankhwala ena omwe angachepetse mwayi wokhala ndi zovuta komanso kukhalabe ndi magazi.
Odwala
Irina, wazaka 53, Moscow
Ndinayenera kumwa mankhwala a Enap nthawi yayitali, yomwe ndinasankha kugula ndekha. Atapanikizika kwambiri, adapita kuchipatala. Adotolo adalemba Lozap Plus. Mankhwalawa adatengedwa m'mawa, zotsatira zake zidawonekera patatha masiku atatu. Katundu wa diuretic amathandizanso, chifukwa panali zotupa, koma chifukwa cha mankhwalawa amachepetsa.
Elena, wazaka 47, Kemerovo
Mothandizidwa ndi Lozap Plus ndakhala ndikugwiriridwa kwazaka pafupifupi zisanu. Munthawi imeneyi, kunalibe mankhwala osokoneza bongo, choncho mankhwalawa akupitilizabe kuthandiza. Kupanikizika kumakhalabe kwachilendo masana onse, kotero ndimamwa mankhwalawa katatu patsiku. Zotsatira zoyipa sizinachitike, chomwe ndichofunikira kwambiri pakuwonjezera matenda oopsa.
Olga, wazaka 54, Rostov
Ngati idapulumutsidwa ku edema mothandizidwa ndi mbewu zamankhwala zomwe zimakhala ndi diuretic katundu, ndiye kuti sizingatheke kutsitsa kuthamanga popanda mankhwala. Kuchipatala adalimbikitsa kutenga Lozap Plus. Chidacho ndichotsika mtengo, koma chothandiza, chifukwa chitha kuchepetsa kukakamiza kwa 210/110 kufika pamlingo wovomerezeka.
