Momwe mungagwiritsire ntchito Atorvastatin-Teva?

Atorvastatin-Teva ndi m'badwo watsopano wama statins. Mankhwalawa amadziwika kuti ndi othandiza pochiza matenda a cholesterol yayikulu magazi.

Asanagwiritse ntchito, wodwalayo ayenera kudziwa zambiri zamalonda, aziganizira zomwe zikuwoneka, komanso samalani ndi chidziwitso chazotsatira zake.

Dzinalo Losayenerana

Atorvastatin, Atorvastatin.

ATX

C10AA05.

Kutulutsa mafomu ndi kapangidwe kake

M'mabungwe azachipatala ndi malo a mankhwala, mankhwalawa amaperekedwa mwanjira ya mapiritsi. Zotsalazo zimakhala ndi matuza, kenako m'matumba a pepala lalikulu.

Fomu ya kipimo imakulungidwa ndi filimu ndipo amalemba mbali zonse za chinthu. Mapiritsi amaperekedwa ndi manambala otsatirawa:

• 93 ndi 7310 pambali zotsutsana za mapiritsi a 10 mg (10 mg mapiritsi);
• 93 ndi 7311 (20 mg aliyense);
• 93 ndi 7312 (40 mg aliyense);
• 93 ndi 7313 (80 mg aliyense).

Chithandizo chogwira mankhwalawa ndi calcium calcium.

Atorvastatin-Teva ndi m'badwo watsopano wama statins.

Zothandiza:

• shuga wogwiritsa ntchito popanga mankhwala;
• mawonekedwe osakwanira a maselo owonda kwambiri a polyvinylpyrrolidone;
• Eudragit E100;
• alpha tocopherol macrogol kuperekera;
• cellulose sodium mchere;
• antihypoxant yomwe imakhudza mtundu wa maselo osinthika ngati vuto la kuchepa kwa oxygen.

Danga lapamwamba kwambiri lili ndi opadray YS-1R-7003: polysorbate-80, hypromellose 2910 3cP (E464), titanium dioxide, hypromellose 2910 5cP (E464), macrogol-400.

Zotsatira za pharmacological

Mankhwala ndi othandizira kutsitsa lipid omwe amalepheretsa kuyambiranso kwa enzyme HMG-CoA reductase. The yogwira pophika piritsi amakhudza kuchuluka kwa cholesterol biosynthesis, amawongolera kuchuluka kwa lipoproteins mu madzi am`magazi, kumawonjezera kuchuluka kwa chiwindi cholandilira.

Zomwe zimagwira popanga piritsi zimakhudza kuchuluka kwa cholesterol biosynthesis.

Nthawi yomweyo, mankhwalawa amakhudza kuchepa kwa apolipoprotein B m'magazi (onyamula mafuta osafunikira a cholesterol) ndi triglycerides (wopanga mafuta m'thupi).

Chifukwa chake, mankhwalawa amachepetsa mwayi wokhala ndi matenda oyamba ndi magazi, amachepetsa chiopsezo cha matenda a mtima ndi stroko.

Malinga ndi maphunziro azachipatala, mankhwalawa amachepetsa kuchuluka kwa cholesterol ya LDL ndi 41-61%, apolipoprotein B - ndi 34-50%, triglycerides - mwa 14-33%.

Pharmacokinetics

Yogwira pophika mankhwala ali mu madzi am`magazi 30-60 Mphindi.

Zinthu zomwe zimapezeka mu piritsi zimapukusidwa kudzera mu chiwindi ndipo zimapukusidwa mu ndulu kwa maola 14, ndikusunga zomwe zimapangitsa kuti pakhale zoletsa (mpaka maola 30).

Gawo lochita ntchito silichotsedwa mthupi ndi kuyeretsa kowonjezereka kwa magazi.

M'mabungwe azachipatala ndi malo a mankhwala, mankhwalawa amaperekedwa mwanjira ya mapiritsi. Zotsalazo zimakhala ndi matuza, kenako m'matumba a pepala lalikulu.

Zomwe zimayikidwa

Mankhwala amaphatikizidwa ndi mankhwala otsatirawa:

1. Kusintha kwa pathological komwe kumalumikizidwa ndi kuchuluka kwa mowa wa polycyclic lipophilic m'magazi am'magazi: chachikulu, heterozygous achibale komanso osakhala achibale hypercholesterolemia.
2. Kuchuluka kwachilendo kwa lipids ndi lipoproteins: mtundu wosakanikirana kapena wophatikizidwa IIa ndi IIb hyperlipidemia malinga ndi Fredrickson. Chithandizo chimayikidwa limodzi ndi zakudya, zotsatirapo zomwe chakudya chimapangidwa kuti muchepetse cholesterol ya LDL, apolipoprotein B ndi triglycerides ndikuwonjezera cholesterol ya HDL.
3. Minyezi ya plasma yachepa ya ma beta-lipoproteins ndi ma chylomicrons, omwe amachititsa kuchepa kwa mavitamini A ndi E: mtundu wa III dysbetalipoproteinemia malinga ndi Fredrickson.
4. Elevated triglycerides (mtundu IV malinga ndi Fredrickson). Mankhwalawa amadziwitsidwa ngati zakudya zochizira sizothandiza.
5. Homozygous achiberekero hypercholesterolemia, kuchotsedwa kwa njira yomwe limagwiritsidwa ntchito pakudya.
6. Chiwopsezo chowonjezeka cha stroke, myocardial infarction, angina pectoris.
7. Kukhalapo kwa zinthu zitatu kapena zowopsa: chikazi cha amuna, kuchuluka kwa ziwonetsero zama thupi, zaka zosaposa zaka 55, hypertrophy yamitsempha, matenda a shuga, mavuto amtundu wa impso, zotumphukira za m'matumbo, matenda obadwa nawo m'matumbo a digiri yoyamba.

Mankhwala akuphatikizidwa ndi mankhwala omwe ali ndi chiopsezo chambiri chotupa, myocardial infarction, angina pectoris.

Contraindication

Mankhwalawa ali ndi zotsutsana zotsatirazi:

• tsankho limodzi ndi zigawo zikuluzikulu za mankhwala;
• kulephera kwa thupi kuyamwa lactose;
• kusowa kwa Lapp-lactase enzyme, matenda a chonyamula mapuloteni a shuga ndi galactose;
• okwera chiwindi michere;
• pachimake kapena matenda a chiwindi;
• kulephera kwa chiwindi;
• kukonzekera pakati, nthawi yobala mwana kapena yoyamwitsa;
• matenda a neuromuscular (myopathy);
• ochepa.

Hepatic insufflication ndi contraindication kumwa mankhwalawa.

Ndi chisamaliro

Mankhwala ayenera kumwedwa mosamala pamene:

• matenda a chiwindi;
• kusinthana kolakwika kwa zinthu;
• kukhalapo kwa zovuta mu endocrine ndi m'mimba dongosolo;
• matenda owopsa (sepsis);
• kugwidwa kwa khunyu kosalamulirika;
• kukhalapo kwa kuvulala kambiri;
• kukanika kwa minofu ndi mafupa;
• uchidakwa.

Pamaso pa kuphwanya dongosolo la endocrine, mankhwalawa ayenera kumwedwa mosamala.

Munthu amene wachitidwa opareshoni nthawi yayitali ndi mapiritsi amayenera kuyang'aniridwa pafupipafupi ndi akatswiri azachipatala kuti adziwe zovuta zomwe zingachitike.

Mkazi yemwe amagwiritsa ntchito mankhwalawa ayenera kugwiritsa ntchito njira zabwino zakulera.

Momwe mungatenge atorvastatin-Teva

Mankhwala amalimbikitsidwa kuti azigwiritsidwa ntchito pokhapokha akuwonetsedwa.

Chithandizo chimaphatikizapo kugwiritsa ntchito mapiritsi potsatira ndondomeko ya hypocholesterolemic.

Posankha mulingo woyenera wabwino kwambiri (10-80 mg), dokotala amatenga ngati njira zowunikira, poganizira za kuchuluka kwa cholesterol ya LDL. Mayeso owongolera kuti asinthe njira zosankhidwa zamankhwala amachitika masiku 14-28 onse.

Mu hypercholesterolemia yoyamba komanso yophatikiza hyperlipidemia, muyezo Mlingo 10 mg mu maola 24.

Ndi homozygous achibale hypercholesterolemia - 80 mg pa tsiku.

Ngati kuphwanya kuchuluka kwa lipid - 10 mg mu 24 maola. Mukamayesedwa ndi dokotala, mulingo wake umasinthidwa ndipo ngati kuli koyenera, umachulukitsa mpaka 80 mg.

Zotsatira zakumwa mankhwalawa zimawonekera patatha milungu iwiri.

Mankhwala amalimbikitsidwa kuti azigwiritsidwa ntchito pokhapokha akuwonetsedwa.

Kumwa mankhwala a shuga

Pogwiritsa ntchito ma statins, kuchuluka kwa shuga m'magazi kumachuluka, kotero kupanga hyperglycemia ndikotheka.

Zotsatira zoyipa

Matumbo

Nthawi zambiri, zotsatira zoyipa zimachitika monga kupweteka kwam'mimba, kutentha kwa mtima, nseru, kutuphuka ndi kudzimbidwa. Izi zimayamba kufooka mu nthawi ya chithandizo.

Zotsatira zoyipa kwambiri zimaphatikizapo kutupa m'mimba, kapamba kapena mucous membrane wa esophagus, intrahepatic cholestasis ndi anorexia.

Pakati mantha dongosolo

Nthawi zina, wodwala angaonekere:

• Chizungulire
• mutu
• kufooka kwathunthu ndi kuchepa;
• kuleka kukumbukira kwakanthawi kochepa;
• kudziwa zamkati (kumverera kwa tsekwe, kumva kugunda, kumva kugunda);
• kuchepa chidwi chazosangalatsa zakunja;
• kuwonongeka kwa mitsempha yotumphera;
• kugona ndi zoopsa;
• asthenic syndrome.

Nthawi zina, wodwalayo amatha kudwala komanso kufooka.

Kuchokera ku kupuma

Zotsatira zoyipa izi ndizotheka:

• mphumu ya bronchial;
• kusokoneza kuwonongeka kwa mapapo;
• kutupa kwa mphuno;
• chibayo

Pa khungu

Nthawi zina, mabala ndi matuza amapezeka pakhungu la wodwalayo chifukwa cha zomwe zimachitika. Mwina kupangidwa kwa chotupa pa polymorphic pa khungu ndi ma mucous membrane, maonekedwe a eczema ndi seborrhea, kukula kwa poermal necrolysis yoopsa.

Nthawi zina, mabala ndi matuza amapezeka pakhungu la wodwalayo chifukwa cha zomwe zimachitika.

Kuchokera ku genitourinary system

Kugwiritsa ntchito mankhwalawa kungayambitse:

• kuchuluka kukodza;
• kulephera;
• polakiuria;
• kuchuluka kwa usiku kukodza masana;
• leukocyturia;
• mawonekedwe a magazi mumkodzo;
• kusabala ndikuphwanya ejaculation;
• kutupa kwa Prostate.

Kuchokera pamtima

Mwa odwala ena, pakumwa mapiritsi, kuchuluka kwa mapulosi m'magazi kumatsika, kutupa kwa khoma la venous kumachitika, kuchepa kwa magazi, kuchepa kwa thupi ndi angina.

Kuchokera ku minculoskeletal system

Odwala ena amadzazindikira:

• kusapeza bwino ndi kupweteka m'munsi mwa msana;
• minofu kukokana ndi hypertonicity;
• kufooka kwa minofu;
• kuchuluka kwambiri kwa myopathy;
• nyamakazi;
• kupweteka kwapakati molumikizana.

Zotsatira zoyipa kuchokera ku minculoskeletal system: nyamakazi.

Matupi omaliza

Monga momwe thupi limagwirira ntchito ndizotheka:

• urticaria;
• kuyabwa
• zotupa
• anaphylactic mantha;
• kutupa kwa pakhungu, minyewa yolumikizira kapena mucous nembanemba.

Malangizo apadera

Kuyenderana ndi mowa

Kugwiritsa ntchito pamodzi mapiritsi ndi mowa kumathandizira, kumawononga thanzi la wodwalayo.

Kugwiritsa ntchito pamodzi mapiritsi ndi mowa kumathandizira, kumawononga thanzi la wodwalayo.

Zokhudza mphamvu pakuwongolera njira

Zotsatira zoyipa izi zikachitika, kudziyendetsa nokha nkoletsedwa.

Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere

Mankhwalawa sayenera kumwa pa nthawi yoyembekezera komanso poyamwitsa.

Kukhazikitsidwa kwa Atorvastatin-Teva kwa ana

Mankhwala contraindicated ana.

Mankhwala contraindicated ana.

Gwiritsani ntchito mu ukalamba

Kukalamba sikukulepheretsa kugwiritsa ntchito mankhwalawa pakamwa: chiwopsezo cha zotsatira zoyipa sichikula, mphamvu ya mankhwala sikuchepa.

The ntchito aimpso kuwonongeka

Mapiritsi amayenera kudyedwa moyang'aniridwa ndi dokotala.

Gwiritsani ntchito ntchito yolakwika ya chiwindi

Kugwiritsa ntchito mankhwalawo kumaletsedwa pachimake komanso matenda osachiritsika a matenda a chiwindi, komanso kuwonjezeka koperewera kwa milingo ya transaminases m'magazi (katatu kapena kuposanso poyerekeza ndi chizolowezi).

Kugwiritsa ntchito mankhwalawo kumaletsedwa pachimake komanso matenda a chiwindi, komanso kuchuluka kwachulukidwe ka magazi m'magazi.

Odwala aimpso kulephera

Potere, adokotala amapita kukayezetsa wodwalayo, kenako mankhwala atamulembera kuchepetsedwa Mlingo kapena kutsika kwa lipid.

Bongo

Pogwiritsa ntchito mankhwala ochulukirapo m'thupi, wodwalayo amakhala ndi zotsatirazi:

• kumverera kowuma ndi kuwawa mkamwa;
• kusanza ndi kusanza
• dyspepsia.

Pogwiritsa ntchito mankhwala ochulukirapo m'thupi, wodwalayo amatha kusanza.

Pakakhala vuto la bongo, m'mimba mumachitika, kenako ndikuwunika kuchuluka kwa CPK m'magazi.

Kuchita ndi mankhwala ena

Kuphatikiza kophatikizidwa

Pa chithandizo, ndikofunikira kupatula kugwiritsa ntchito:

• mafupa;
• macrolide mankhwala;
• nicotinic acid;
• azole antifungal othandizira;
• madzi a mphesa.

Pa chithandizo, ndikofunikira kupatula kugwiritsa ntchito madzi a mphesa.

Osavomerezeka kuphatikiza

Mankhwala ndi osayenera kugwiritsa ntchito molumikizana ndi:

• Cyclosporine;
• HIV protease zoletsa;
• Nefazodone;
• othandizira omwe amachepetsa kuchuluka kwa mahomoni amkati mwathunthu.

Kuphatikiza komwe kumafunikira kusamala

Wodwalayo akulangizidwa kuti afotokoze zavuto lililonse la thanzi lanu kwa adokotala ngati mapiritsi ake amagwiritsidwa ntchito nthawi imodzi ndi:

• P-glycoprotein zoletsa;
• Digoxin;
• njira zakulera za pakamwa zomwe zimakhala ndi ethinyl estradiol ndi norethisterone;
• Colestipol;
• Warfarin.

Wodwalayo akulangizidwa kuti afotokoze zavuto lililonse la thanzi kwa dokotala ngati mapiritsi ake amagwiritsidwa ntchito pamodzi ndi P-glycoprotein inhibitors.

Analogi

Mankhwala othandizira, omwe ali ndi zinthu zofananira:

• Abender
• Actastatin;
• Astin;
• Atomax;
• Atocor
• Atorem;
• Atoris;
• Atorvastatin;
• Atorvastatin alkaloid;
• Atorvastatin-LEXVM;
• Atorvastatin-SZ;
• Vazator;
• Lipoford;
• Liprimar;
• Novostat;
• Torvazin;
• Torvacard
• Torvas
• Tulip.

Atorvastatin ndi amodzi mwa fanizo la mankhwala.

Vazator ndi amodzi mwa fanizo la mankhwalawa.

Novostat ndi amodzi mwa fanizo la mankhwalawa.

Zomwe zili bwino - Atorvastatin kapena Atorvastatin-Teva?

Asanaganize zogwiritsa ntchito mankhwala omwewo, mosasamala kanthu chifukwa chake, wodwalayo ayenera kuphunzira zambiri zam'mapiritsiwo ndikuwonana ndi dokotala kuti athe kulowa m'malo mwake.

Dzina loti Atorvastatin (popanda kuwonjezera dzina la wopangiralo) limanenanso kuti mankhwalawa adapangidwa ndi bungwe lomwe silingakhale logulitsa lodalirika la mankhwala.

Kupita kwina mankhwala

Mapiritsiwo amawagawa malinga ndi mankhwala, omwe ali ndi dzina la mankhwalawo m'Chilatini, amalembedwa pamakalata a chipatala ndikuwatsimikizira ndi chidindo.

Kodi ndingagule popanda kulandira mankhwala?

Pali milandu yopeza mankhwala osagwiritsa ntchito mankhwala (kudzera m'masitolo a pa intaneti). Koma kumwa mankhwalawa osasankhidwa ndi katswiri kungayambitse kuvulaza kwamunthu.

Mankhwalawa amayenera kusungidwa kuti ana asawatenthedwe pofika 30 ° C.

Mtengo wa Atorvastatin-Teva

Mtengo wa mankhwalawa wopanga ku Israeli umasiyana kuchokera ku 95 mpaka 600 rubles. kutengera mlingo komanso malo ogulitsa.

Zosungidwa zamankhwala

Mankhwalawa amayenera kusungidwa kuti ana asawatenthedwe pofika 30 ° C.

Tsiku lotha ntchito

Osapitilira zaka ziwiri kuchokera tsiku lomwe adatulutsa.

Wopanga

Kampani - Teva Pharmaceutical Viwanda, Israel.

Ndemanga Atorvastatin-Teva

Madokotala

Vitaliy, wazaka 42, Ufa

Mankhwala ochokera ku Teva amapangidwa ndi kampani yodalirika yamankhwala, chifukwa chake mankhwalawa amaperekedwa kwa odwala omwe ali ndi vuto loyenerera. Nthawi zina odwala amadandaula chifukwa chosagwiritsa ntchito mankhwalawa. Komabe, atapempha kuti awonetse phukusi logula, zimapezeka kuti mankhwalawo amapangidwa ndi kampani ina yodziwika pang'ono.

Irina, wazaka 48, Stavropol

M'pofunika kugwiritsa ntchito mankhwalawa monga momwe adanenera dokotala komanso pokhapokha ngati pali zotsutsana. Pazochita zanu zokha, pamakhala zochitika pomwe wodwala yemwe ali ndi matenda a chiwindi adayamba kumwa mapiritsi popanda kufunsa katswiri wazachipatala, zomwe zidamupweteketsa kwambiri.

Renat, wazaka 37, Rostov-on-Don

Odwala sayenera kuiwala za zovuta zomwe mankhwalawa amayambitsa. Pogwiritsa ntchito mapiritsi, odwala amalangizidwa mwamphamvu kuti nthawi zonse azichita kuyezetsa magazi a biochemical.

Odwala

Ilya, wazaka 38, Surgut

Kwa miyezi itatu yotsatira kudya komanso kumwa mankhwala, kuchuluka kwa cholesterol ya LDL kutsika mpaka 3 mmol / L. Chifukwa chake, nditha kunena kuti mapiritsiwa ali ndi zotsatira zabwino, zosiyana pamtengo wotsika uwu. Ndikupangira.

Alexandra, wazaka 29, Izhevsk

Amayi adayikidwa mapiritsi ochepetsa cholesterol. Miyezi itatu yadutsa, koma palibe zotsatira. Koma kuchuluka kwa zoyipa - kusowa tulo, kupweteka mutu, kupweteka kumbuyo.

Marina, wa zaka 32, Voronezh

Ndikukhulupirira kuti ngati pali zovuta ndi cholesterol, ndiye kuti ndibwino kutsatira zakudya ndikusunthira zina. Mankhwalawa samakhudzanso kuchuluka kwa mowa wa lipophilic, koma amayambitsa kutentha kwa mtima ndi mutu. Ndidamwa mapiritsi motsutsana ndi adotolo anga ndipo sindikumvetsa zomwe amatsogozedwa ndi kuperekera mankhwala kwa odwala. Vazator ndi amodzi mwa fanizo la mankhwala.