Ngakhale pali zinthu zabwino za mankhwalawo, Glucophage, zoyipa zomwe aliyense ayenera kudziwa, ali ndi zina zomwe angagwiritse ntchito.
Kuphatikiza apo, wopangayo amapanga Glucofage Long, mankhwala amkamwa omwe amagwiritsidwa ntchito kuti awonjezere kuyankha kwa ma receptor ku timadzi totsitsa-shuga, komanso kugwiritsa ntchito shuga ndi maselo.
Nkhaniyi ithandizira kumvetsetsa zinthu zofunika monga magwiritsidwe, ntchito, mavuto kuchokera ku glucophage, contraindication, kuwunika, mitengo yamtengo wapatali ndi analogues.
Mankhwala
Mankhwala Glucophage amasonyezedwa kwa odwala omwe samadalira insulin, pomwe kuchita masewera olimbitsa thupi komanso zakudya zapadera sizithandiza kutsika kwamisempha. Malangizowo akuti othandizira odwala matenda ashuga amatha kugwira ntchito ngati kunenepa kwambiri kumachitika. Pochita, zimaphatikizidwa ndi zonse insulin mankhwala ndi mitundu ingapo yochepetsera shuga.
Wopanga amatulutsa Glucophage antidiabetesic wothandizira mu mapiritsi a mitundu yosiyanasiyana: 500, 850 ndi 1000 mg. Chomwe chimagwiritsa ntchito mankhwalawa ndi metformin hydrochloride - woimira kalasi yayikulu. Piritsi lililonse la mankhwalawa limaphatikizapo zinthu monga povidone, macrogol (4000, 8000), hypromellose ndi magnesium stearate.
Mtundu wapadera wamasulidwa ndi mankhwala omwe akhala akuchita kwa nthawi yayitali. Mapiritsi amapangidwa mosiyanasiyana Mlingo (Glucofage Long 500 ndi Glucofage Long 750).
Glucophage siyikutsogolera kukula kwa hypoglycemia, ndipo palibenso kulumikizana kowongoka kuzidziwitso zamagulu a shuga. Mukamatenga Glucofage mwa anthu athanzi, palibe kuchepa kwa glycemia yomwe ili pansi pa malire a 3.3-5.5 mmol / L. Matenda a shuga amakwaniritsidwa chifukwa cha mankhwala otsatirawa:
- Kupanga insulin kwa beta maselo a beta.
- Kuchuluka kwa chiwopsezo cha "maselo chandamale" mapuloteni ndi adipose minofu ya insulin.
- Kupititsa patsogolo kwa kukonza kwa dzuwa ndi minyewa.
- Chotsitsa chimbudzi cha chakudya cham'mimba mwa chimbudzi.
- Kutsitsa kuchuluka kwa shuga chiwindi.
- Kupititsa patsogolo kagayidwe.
- Kuchepetsa kuzama kwa cholesterol, otsika ochepa lipoproteins ndi triglycerides.
- Kuchepetsa thupi kwa odwala omwe ali ndi kunenepa kwambiri (Glucofage acidifying acid acid).
Pogwiritsa ntchito pakamwa pa Glucofage metformin, hydrochloride imalowa mwachangu m'matumbo am'mimba, ndipo mawonekedwe ake apamwamba amawonekera pambuyo pa maola awiri ndi theka. Glucophage Long, m'malo mwake, imamizidwa nthawi yayitali, chifukwa chake imangotengedwa kamodzi kokha pa tsiku.
Gawo logwira ntchito silikugwirizana ndi mapuloteni, omwe amafalikira mwachangu kuzinthu zonse zama cell a thupi. Metformin imakumbidwa limodzi ndi mkodzo.
Anthu omwe ali ndi vuto la impso ayenera kudziwa kufunikira kwa kuletsa kwa mankhwala mu minofu.
Malangizo ogwiritsira ntchito mapiritsi
Mankhwala onsewa (Glucophage ndi Glucophage Long) amagulidwa ku mankhwala, okhala ndi malangizo a endocrinologist nawo. Dokotalayo amapereka mankhwala malinga ndi kuchuluka kwa glucose ndi zizindikiro zake odwala matenda ashuga.
Kumayambiriro kwa mankhwala, tikulimbikitsidwa kudya 500 mg kawiri pa tsiku. Pakatha milungu iwiri, amaloledwa kuwonjezera Mlingo. Tiyenera kudziwa kuti mutatenga Glucofage woyamba masiku 10 mpaka 14 pali zotsatira zoyipa zomwe zimakhudzana ndi kusintha kwa thupi ndi gawo lomwe limagwira. Odwala amadandaula za kuphwanya kwam'mimba, monga, kugwidwa ndi mseru kapena kusanza, kudzimbidwa kapena, matendawa, kutsekemera kwazitsulo.
Mlingo wokonza ndi 1500-2000 mg patsiku. Kuti muchepetse mavuto chifukwa chomwa mankhwalawa, muyenera kugawa mlingo wa tsiku ndi tsiku katatu. Zolemba malire patsiku zimaloledwa kudya mpaka 3000 mg.
Ngati wodwalayo agwiritsa ntchito mankhwala ena a hypoglycemic, ndiye kuti ayenera kusiya kudya ndi kuyamba kulandira chithandizo ndi Glucofage. Mukaphatikiza mankhwalawa ndi insulin, muyenera kutsatira mlingo wa 500 kapena 850 mg kawiri kapena katatu patsiku, komanso 1000 mg kamodzi patsiku. Anthu omwe ali ndi vuto la kulephera kwa impso kapena matenda ena a impso, ndikofunika kusankha mlingo wa mankhwalawo payekha. Zikatero, anthu odwala matenda ashuga amapanga kamodzi mwa miyezi 3-6.
Gwiritsani ntchito Glucofage Long 500 ndiyofunikira kamodzi patsiku madzulo. Kusintha kwa mankhwala kumachitika kamodzi pakadutsa milungu iwiri iliyonse. Glucophage Long 500 ndi koletsedwa kugwiritsa ntchito zoposa kawiri pa tsiku. Ponena za kuchuluka kwa 750 mg, ziyenera kudziwitsidwa kuti mlingo waukulu ndi kawiri patsiku.
Kwa odwala aubwana ndi unyamata (wopitilira zaka 10) amaloledwa kudya mpaka 2000 mg patsiku. Kwa odwala opitilira zaka zopitilira 60, dotoloyo amasankha payekha chifukwa cha kuchepa kwa impso.
Mapiritsiwo amatsukidwa ndi kapu yamadzi opanda, osaluma kapena kutafuna. Ngati mungadumphe kumwa mankhwalawo, simungawonjezere kuchuluka kwake. Kuti muchite izi, muyenera kumwa nthawi yomweyo ya Glucofage.
Kwa odwala omwe amamwa oposa 2000 mg a glucophage, palibe chifukwa chomwa mankhwala omwe atulutsidwa nthawi yayitali.
Pogula othandizira odwala matenda ashuga, onetsetsani kuti nthawi yake yatha, ndi zaka 500 ndi 500 mg kwa Glucofage, ndi zaka zisanu kwa Glucofage 1000 mg - zaka zitatu. Ulamuliro wa kutentha komwe ma CD umasungidwapo suyenera kupitirira 25 ° C.
Chifukwa chake, kodi Glucophage imayambitsa mavuto, ndipo imakhala ndi zotsutsana? Tiyeni tiyese kuzilingalira mopitirira.
Contraindication hypoglycemic mankhwala
Mankhwala omwe amapezeka nthawi yayitali komanso nthawi yayitali amakhala ndi zotsutsana zapadera komanso zoyipa.
Pofuna kupewa zoyipa zomwe zimachitika mutatha kumwa Glucofage, odwala matenda ashuga amafunika kukambirana zonse zamatenda ndi dokotala.
Phukusi lililonse la mankhwalawo limatsagana ndi pepala loyika lomwe limakhala ndi zotsutsana zonse ndi mankhwala a Glucophage.
Main contraindication ndi:
- kuchuluka kwa zinthu zomwe zimapezeka;
- matenda ashuga ketoacidosis;
- chikomokere, matenda a shuga;
- kukulitsa kwa ma pathologies omwe amatsogolera kuwoneka kwa minofu hypoxia (myocardial infarction, kupuma / mtima kulephera);
- kukanika kwa chiwindi kapena kulephera kwa chiwindi;
- aimpso ntchito kapena kulephera kwa aimpso (creatinine osakwana 60 ml mphindi imodzi);
- pachimake zinthu zomwe zimawonjezera mwayi wa kukanika kwa impso (kutsegula m'mimba, kusanza), kugwedezeka, matenda opatsirana;
- kuvulala kwakukulu, komanso kulowererapo;
- nthawi ya bere ndi mkaka wa m`mawere;
- uchidakwa kwambiri, komanso uchidakwa.
- masiku awiri isanachitike komanso itatha mayeso a radioisotope ndi x-ray ndikuyambitsa gawo lokhala ndi ayodini;
- lactacidemia, makamaka m'mbiri.
Kuphatikiza apo, ndizoletsedwa kumwa mankhwalawa ngati mugwiritsa ntchito hypocaloric zakudya (zosakwana 1000 kcal patsiku).
Zotsatira zoyipa ndi bongo
Kodi mavuto amakumana ndi chiyani?
Monga tanena kale, Glucophage imakhudza kugwira ntchito kwa m'mimba thirakiti koyambira kwamankhwala.
Kuzolowera thupi kumayendera limodzi ndi zizindikiro monga mseru, kusanza, chimbudzi, kudzimbidwa, kulawa zachitsulo, pakamwa pouma, kusowa chilakolako cha chakudya.
"Zotsatira zoyipa" zimalumikizidwa ndi zovuta zina pakugwira ntchito kwa ziwalo zamkati.
Choyamba, zotsatira zoyipa zimawonetsedwa:
- Kukula kwa lactic acidosis.
- Kupezeka kwa kuchepa kwa vitamini B12, komwe kuyenera kutengedwa mozama ndi meWIblastic anemia.
- Khungu komanso kusintha kosiyanasiyana monga pruritus, zotupa, ndi erythema.
- Zotsatira zoyipa za chiwindi, kukula kwa chiwindi.
Ndi bongo wambiri, kukula kwa dziko la hypoglycemic sikunawonedwe. Komabe, lactic acidosis nthawi zina imatha kuchitika. Zizindikiro zomwe zingakhalepo zingaphatikizepo kusazindikira bwino, kukomoka, kusanza, nseru, chizungulire, kupweteka kwa mutu, ndi ena.
Zoyenera kuchita ngati wodwala akuonetsa zizindikiro za lactic acidosis? Iyenera kuperekedwa kuchipatala posachedwa kuti itsimikizire kuchuluka kwa mkaka wa lactate. Monga lamulo, dokotala amamuwonetsa hemodialysis ngati njira yabwino kwambiri yochotsera lactate ndi metformin hydrochloride m'thupi. Chithandizo cha Syndrome chimachitidwanso.
Malangizowo sakusonyeza njira zosaphatikizidwa zomwe zimagwiritsidwa ntchito limodzi ndi Glucofage, zimatha kukweza msanga kapena kuchepa kwa msanga. Simungathe kuphatikiza chithandizo cha Glucofage ndi:
- antipsychotic;
- danazol;
- chlorpromazine;
- beta2-sympathomimetics
- mankhwala a mahomoni;
- "loop" okodzetsa;
- Mowa.
Kuphatikiza apo, sikulimbikitsidwa kuphatikiza kuyendetsa kwa Glucofage ndi ayodini okhala ndi ayodini.
Kugwiritsa ntchito mankhwalawa pofuna kuchepetsa thupi komanso thanzi la azimayi
Odwala ambiri amadabwa chifukwa chake glucophage imakhudzanso kuchepa thupi. Popeza mankhwalawa amalimbikitsa acidization yamafuta achilengedwe ndikuchepetsa kugwiritsa ntchito mafuta, zimayambitsa mwachindunji kuchepa kwambiri kwa thupi.
Chimodzi mwazotsatira zoyipa, kulephera kudya, odwala matenda ashuga ambiri amawona kuti ndi othandiza, chifukwa amachepetsa kudya kwawo tsiku ndi tsiku. Komabe, mphamvu ya mankhwalawa imatha kuchepetsedwa chifukwa chakuwonjezeka kwa acidic m'thupi. Chifukwa chake, pakulandila Glucofage, sikulimbikitsidwa kuti mudzikweze kwambiri ndi masewera olimbitsa thupi. Koma palibe amene analetsa kudya mokwanira. Ndikofunikira kusiya zakudya zamafuta ndikugaya chakudya mosavuta.
Kutalika kwa mankhwalawa kuonda sikuyenera kupitilira masabata 4-8. Musanagwiritse ntchito mankhwalawa, muyenera kufunsa akatswiri odziwa zaumoyo kuti mupewe kuvulazidwa komanso kukhala ndi hypoglycemia mu matenda a shuga.
Kafukufuku waposachedwa awonetsa kuti kumwa mankhwala ndikothandiza pakubala. Kuphatikiza apo, imatengedwa kuti ndi polycystic, yomwe idapangitsa kuti 57% ya omwe akulephera kukhala ndi ana. Izi zitha kupezeka chifukwa cha metabolic syndrome kapena kukana insulin.
Poyamba, odwala ambiri amakhala ndi zizindikiro monga kuchedwa, kusakhazikika, komanso cystitis. Zizindikirozi sizikhala bwino ndipo zimafunikira kulumikizidwa mwachangu ndi dokotala wazamankhwala.
Kuphatikiza kwa Glucophage ndi Duphaston kumathandizira kukhazikika kwamadzi.
Mtengo, kuwunika ndi zofanana
Glucophage imadabwitsa osati ndi ntchito yake, komanso pamitengo yosangalatsa. Chifukwa chake, mtengo wa 1 phukusi la Glyukofage umasiyana ndi ma ruble a 105 mpaka 310, ndikuchitapo kanthu kwa nthawi yayitali - kuchokera pa ma ruble 320 mpaka 720, kutengera mtundu wa kumasulidwa.
Ndemanga za odwala omwe amamwa mankhwalawa ndi zabwino kwambiri. Glucophage sichimayambitsa hypoglycemia ndipo imakhazikitsa shuga mu odwala matenda ashuga. Komanso, ndemanga zambiri zikuwonetsa kuyenera kwa njira yothetsera kuwonda. Mwachitsanzo, mwachitsanzo, ndemanga:
Lyudmila (wazaka 59): "Ndidawona Glucofage pazaka zitatu zapitazi, shuga sapitirira 7 mmol / L. Inde, kumayambiriro kwamankhwala ndidadwala, koma ndikuganiza ngati mukudwala, mutha kuthana nawo. Ngati mupitiliza kumwa mankhwala, "Zaka zitatu zapitazo, thupi langa linali lolemera makilogalamu 71, mothandizidwa ndi chida ichi kulemera kwathu konse kunatsikira mpaka 64 kg. Vomerezani, zotsatira zabwino. Zachidziwikire, simungachite popanda kudya komanso kulipiritsa zachipatala."
Komabe, pali malingaliro oyipa okhudza mankhwalawa. Amalumikizidwa ndi kudzimbidwa komanso kusintha kwina kwamthupi. Mwachitsanzo, kupanikizika kowonjezereka, kuvuta kwa impso. Komanso, mankhwalawa amatha kuyambitsa kukulira kwa cholecystitis, atrive fibrillation, kuchuluka kwa zizindikiro za psoriasis, mwa anthu omwe akudwala matendawa. Ngakhale ubale weniweni pakati pa matenda ndikumwa mankhwalawa sunakhazikike kwathunthu.
Popeza Glucophage imakhala ndi chinthu chotchuka padziko lonse lapansi - metformin, imakhala ndi mitundu yambiri. Mwachitsanzo, Metformin, Bagomet, Metfogamma, Formmetin, Nova Met, Glformin, Siofor 1000 ndi ena.
Glucophage (500, 850, 1000), komanso Glucophage 500 ndi 750 ndi mankhwala othandiza a matenda ashuga a 2. Nthawi zambiri, mankhwala omwe amayambitsa mavuto ena amangogwiritsidwa ntchito molakwika. Akagwiritsidwa ntchito moyenera, amakhala ndi thanzi labwino ndipo amachotsa matenda oopsa a matenda ashuga.
Zambiri zokhudzana ndi Glucofage zimaperekedwa mu kanema munkhaniyi.
