Wessel Douay f amatanthauza mankhwala omwe amathandiza kuchepetsa magazi omwe amapanga magazi. Ndiwofotokozera mwachindunji komanso mwachangu. Amagwiritsidwa ntchito popanga zovuta za matenda omwe amaphatikizidwa ndi kuchuluka kwa kuphatikizana kwa maselo.
Wessel Douay f amatanthauza mankhwala omwe amathandiza kuchepetsa magazi omwe amapanga magazi.
Dzinalo Losayenerana
INN: Sulodexide.
ATX
Nambala ya ATX: B01A B11.
Kutulutsa mafomu ndi kapangidwe kake
Mankhwalawa amapezeka m'mitundu iwiri yayikulu: makapisozi a gelatin zofewa komanso yankho lomveka bwino la jakisoni.
Njira Zothetsera
Mbale umodzi nthawi zonse umakhala ndi 600 LU yofunikira yogwiritsira ntchito, yomwe ndi sodeodeide. Zinthu zothandiza: Madzi oyeretsedwa kuti aphatikizidwe jakisoni ndi kashiamu yaying'ono ya sodium.
Mbale umodzi nthawi zonse umakhala ndi 600 LU yayikulu yogwira ntchito.
Njira yothetsera vutoli ndi yowonekera bwino, yokhala ndi chikasu. Mbale iliyonse imakhala ndi 2 ml yankho labwino. M'magawo asanu ndi ma ampoules asanu. Mu kakhadibhodi mumatha kukhala phukusi limodzi kapena awiri okhala ndi maselo.
Makapisozi
Makapu ofewa a gelatin. Muli 250 LU yazomwe zimagwira. Mwa zina zowonjezera: silicon dioxide, kuchuluka kwa sodium lauryl sarcosinate, ena triglycerides.
Makapisozi ndi ofiira. Piritsi lililonse lili ndi kuyimitsidwa kotuwa. Nthawi zina mhunzi imatha kukhala yapinki kapena kirimu.
Mapiritsi onse amayikidwa m'matumba apadera a 25 makapisozi pachilichonse. Pankhaniyi, phukusi loyambirira limayenera kukhala ndi malangizo a malamulo ogwiritsira ntchito.
Zotsatira za pharmacological
Mankhwala amatanthauza anticoagulants zabwino. Gawo lalikulu ndi sulodexide. Mu kapangidwe kake pali mitundu iwiri ikuluikulu: dermatan sulfate ndi heparin.
Chifukwa cha kukhalapo kwa heparin, mphamvu ya anticoagulant yamankhwala imawonetsedwa. Tizigawo ta hepatini timathandizira kuti masokosi ambiri azikundana.
Mphamvu ya antithrombotic imatheka pochepetsa chizolowezi cha fibrinogen mu plasma yamagazi.
Mphamvu ya antithrombotic imatheka pochepetsa chizolowezi cha fibrinogen mu plasma yamagazi. Pankhaniyi, kubisala ndi kapangidwe ka prostacyclin kumachulukitsidwa ndikutchinga kwamphamvu kwa chinthu choyambirira cha X. Wogwiritsa ntchito magazi ambiri amawonjezeka chifukwa cha kuchuluka kwa mankhwalawa. Kukhulupirika kwa maselo onse am'madzi otayika a ziwiya zazikulu kumabwezeretsedwa mwachangu.
Mankhwalawa amathandizira kuchepa kwa triglycerides. Pafupifupi ntchito zonse zamagazi zowonjezera magazi zimapangidwa modabwitsa. Makulidwe amimba am'mimba amachepa, ndipo kuchuluka kwawo kumachepera. Izi ndizofunikira mankhwalawa a matenda a shuga.
Zimatsimikiziridwa kuti mankhwalawa amathandizira kuwonda m'magazi ndipo amalepheretsa mapangidwe a cholesterol plaque, ofunikira kwambiri popewa kunenepa kwambiri kwa odwala omwe ali ndi matenda ashuga.
Pharmacokinetics
Sulodexide imapangidwa mu impso ndi chiwindi. Mosiyana ndi heparin yomwe ili ndi chidwi chogwiritsa ntchito sizimadutsa pakuwonongedwa. Izi zimawongolera njira yothandizira, chifukwa ntchito ya antithrombotic siyikakamizidwa, ndipo njira yochotsa mankhwalawa m'thupi imathandizira kwambiri.
Mafuta amapezeka m'matumbo ang'onoang'ono. Mafuta amachitidwa mu endothelial wosanjikiza kwamitsempha yamagazi. Maola ochepa mutamwa mankhwalawa, umathiridwa mkodzo.
Mafuta amapezeka m'matumbo ang'onoang'ono.
Zizindikiro zogwiritsidwa ntchito
Wessel Douay F amagwiritsidwa ntchito pazochitika zina za m'magazi zomwe zimatha kutsagana ndi kupangika kwachilendo kwa magazi m'ziwiya zazikulu. Potere, kukhulupirika kwa makoma a zotengera sikuphwanyidwa ndipo zolembera za cholesterol sizimapanga.
Zizindikiro zachindunji zogwiritsira ntchito ndi:
- Angiopathy, yomwe imadziwika ndi kuphwanya umphumphu wa makoma a ziwiya zam'madzi komanso chiopsezo chowonjezeka cha kupangika kwa magazi akulu chifukwa chamtima wapamtima.
- Kusokonezeka kwa kayendedwe kabwinobwino ka magazi m'zigawo zikuluzikulu za ubongo.
- Dyscirculatory encephalopathy, yomwe imayamba chifukwa cha matenda osokoneza bongo, matenda oopsa oopsa komanso matenda a mtima a ziwiya zazikulu.
- Vuto la kuchepa kwa mtima, lowonetsedwa ndi kuchepa kwa maluso onse aluntha.
- Phlebopathy, yodziwika ndi mitsempha yakuya, makamaka pamagawo otsika.
- Microangiopathy ndikuphwanya kukhulupirika kwa ma capillaries, omwe amatsogolera kuchepa kwa magazi. Kuphwanya kotereku kumawonedwa mu mitsempha ya mitsempha, mapangidwe a impso, ndi retina.
- Macroangiopathy ndi vuto lozungulira m'matumbo akulu a mtima, impso ndi miyendo.
- Kuchulukitsa kwa magazi.
Matenda onsewa amafunika kuwongoleredwa mwachangu. Chifukwa chake, chithandizo chovuta chogwiritsa ntchito Wessel Douay F chitha kusintha zinthu.
Contraindication
Pali zochitika zina za momwe mankhwalawa amaletsedwera ntchito:
- tsankho la munthu pazigawo zina za mankhwala;
- hemorrhagic diathesis, yomwe nthawi zambiri imayendetsedwa ndi kuchepa kwa nthawi ya magazi;
- DIC;
- chiyambi cha kutenga pakati.
Musanayambe mankhwala osokoneza bongo, muyenera kuonetsetsa kuti palibe zoletsa pa mankhwalawa.
Momwe mungatenge Wessel Douai f
M'milungu iwiri yoyamba ya mankhwala, mankhwalawa amaperekedwa ndi jekeseni. Onse jakisoni wa intramuscular and intravenous mankhwala opatsirana amaloledwa. Zolemba zonse za ampoule - 2 ml ya mankhwalawa - amasungunuka mu 200 ml ya saline yachilengedwe.
M'milungu iwiri yoyamba ya mankhwala, mankhwalawa amaperekedwa ndi jekeseni.
Pambuyo pake, amayamba kumwa mankhwalawo m'mapiritsi. Mankhwalawa ayenera kukhala osachepera mwezi. Gawani kapisozi kamodzi patsiku. Ndikwabwino kumwa mapiritsi pakati pa zakudya zazikulu.
Kuti muchiritsidwe kwakanthawi, tikulimbikitsidwa kulandira chithandizo kamodzi miyezi isanu ndi umodzi. Ngati ndi kotheka, mutha kusintha mankhwalawa kutengera thanzi la wodwala.
Kumwa mankhwala a shuga
Ndi matenda a shuga, mankhwalawa amagwiritsidwa ntchito kwambiri. Chigawo chogwira ntchito sichimangochulukitsa magazi, komanso chimalepheretsa mapangidwe a cholesterol plaque. Pankhaniyi, njira ya chithandizo iyenera kukhala ya masiku 50-60. Mulingo wovomerezeka tsiku lililonse soposa 18 mg.
Zotsatira zoyipa za Wessel Douai f
Zotsatira zoyipa zimachitika kawirikawiri. Amathanso kukhudza ziwalo zosiyanasiyana zamkati. Pali kuphwanya kwam'mimba kachitidwe kake ndi matupi awo sagwirizana.
Ndi matenda a shuga, mankhwalawa amagwiritsidwa ntchito kwambiri.
Matumbo
Pa mbali ya m'mimba ndi matumbo, kukula kwa chimbudzi chokwiya, mawonekedwe a nseru, kusanza ndi kupweteka kwambiri mu epigastrium ndikotheka.
Matupi omaliza
Nthawi zina, kukula kwa thupi lawo siligwirizana ndikotheka. Odwala ambiri amadandaula za kupweteka ndi kuphulika, kuwotcha kwambiri pamalo a jekeseni wamitsempha ya mankhwala. Mutatenga makapisozi, ziwonetsero zimadziwoneka ngati zotupa zapakhungu. Mwazovuta kwambiri, kukulitsa edema ya Quincke kapena anaphylactic kugwedezeka ndikotheka.
Zokhudza mphamvu pakuwongolera njira
Zilibe kukhudzidwa Chifukwa chake, mukatenga, mutha kuyendetsa magalimoto ndi makina olemera. Pokhapokha ngati pakuchitika zoyipa zazikulu, muyenera kupewa kuyendetsa.
Mukamatenga Wessel Douay F, mutha kuyendetsa magalimoto ndi makina olemera.
Malangizo apadera
Chithandizo chikuyenera kuchitika motsogozedwa molunjika ndi zofunikira zonse za coagulogram. Cholinga chake chizikhala pa nthawi ya kukha magazi komanso kuwonongeka kwa magazi. Ndikofunikanso kuganizira za kukhalapo kwa mtima ndi zovuta zina zam'mimba.
Gwiritsani ntchito panthawi yoyembekezera komanso mkaka wa m`mawere
Sizoletsedwa kumwa mankhwala mu trimester yoyamba kubereka. Pali umboni wa zotsatira zabwino za mankhwalawa panthawi yomwe amayi apakati omwe ali ndi matenda ashuga tsiku lomaliza mu 2nd ndi 3 trimesters. Mankhwalawa amagwiritsidwa ntchito poletsa kukhazikika kwa mochedwa gestosis ndi ma pathologies ena okhudzana ndi kuphwanya umphumphu wa makhoma amitsempha yamagazi. Pokonzekera kutenga pakati, muyenera kusiya kulandira.
Sizoletsedwa kumwa mankhwala mu trimester yoyamba kubereka.
Palibe deta yodalirika yokhudza momwe mankhwalawo amakhudzira kupezeka kwa mkaka wa m'mawere. Chifukwa chake, ndibwino kusiya kuyamwitsa pakumwa mapiritsi.
Mlingo wa ana
Zambiri pakugwiritsa ntchito mankhwalawa kwa ana aang'ono sizikupezeka. Kwa ana a zaka 12 zakubadwa, mankhwalawa amawerengedwa pokhapokha ngati pali vuto ladzidzidzi komanso pamunsi yotsika.
Mankhwala ochulukirapo a Wessel Douai
Ngati mupitilira dontho limodzi, magazi amatha kukhala, kutuluka m'malo osiyanasiyana: kuchokera kulumikizana mpaka m'mimba. Pankhaniyi, mankhwalawa atathetsedwa, wodwalayo amapaka jekeseni ya 1% ya protamine sulfate.
Kuchita ndi mankhwala ena
Mfundo zachikhalidwe ndi mankhwala ena sizinafotokozedwebe. Kugwiritsa ntchito nthawi yomweyo ndi mankhwala omwe angakhudze dongosolo la hemostatic sikulimbikitsidwa. Izi zimaphatikizapo ma anticoagulants ndi ma antiplatelet othandizira ena. Kugwirizana kwa Courantil ndi Wessel Douay F sikulimbikitsidwa.
Kugwiritsa ntchito nthawi yomweyo ndi mankhwala omwe angakhudze dongosolo la hemostatic sikulimbikitsidwa.
Kuyenderana ndi mowa
Ndi mowa, achire zotsatira zimachepa.
Analogi
Pali malo ochepa okha, otchuka kwambiri a iwo:
- Sulodexide;
- Angioflux;
- Axparin;
- Clexane.
Potengera njira zawo zochizira komanso zamankhwala, mankhwalawa ndi fanizo lokwanira. Musanasankhe mankhwala alionse kuti alowe m'malo, ndibwino kuonana ndi dokotala. Mitengo yamankhwala onsewa idzakhala yotsika.
Musanasankhe mankhwala alionse kuti alowe m'malo, ndibwino kuonana ndi dokotala.
Kupita kwina mankhwala
Mwayi womasuka wa Wessel Douai f sankho lilibe. Amagwiritsidwa ntchito pokhapokha ngati akusunthira magawo onse a magazi.
Kodi ndingagule popanda kulandira mankhwala?
Imatulutsidwa pokhapokha malinga ndi njira yomwe yaperekedwa mwapadera.
Zochuluka motani
Mtengo udzatengera mtundu wa mankhwala ndi maupanga a mankhwala. Mtengo wa makapisozi ndi ma ruble 2800-3000. Mtengo wa 1 ampoule ukhale ma ruble 200.
Wessel Douai F amamasulidwa pokhapokha malinga ndi njira yomwe yaperekedwa mwapadera.
Zosungidwa zamankhwala
Mankhwalawa amasungidwa m'malo owuma, kutali ndi ana aang'ono, kutentha firiji.
Tsiku lotha ntchito
Moyo wa alumali ndi zaka 5 kuyambira tsiku lopangira, zomwe ziyenera kuwonetsedwa pakapangidwe kake koyambirira.
Wopanga
Production wa Pharmacor, Russia.
Ndemanga za madotolo za Wessel Douai f
Alexander, wazaka 38, wa endocrinologist, ku St. Petersburg: "Nthawi zambiri ndimalimbikitsa mankhwala kuti magazi asungunuke m'mitsempha. Izi ndizofunikira makamaka kwa odwala omwe ali ndi vuto la matenda a shuga a 2 komanso matenda a atherosulinosis omwe amalephera kuzungulira m'munsi. Mankhwalawa nthawi zina amatha kusokoneza magazi a magazi. matenda ashuga komanso kulephera kuzungulira kwa ziwongo zamagalimoto. "
Mankhwalawa sioyenera aliyense chifukwa cha mtengo wake wokwera. Mosamala, iyenera kugwiritsidwa ntchito ndi anthu omwe ali ndi retinopathy ndipo pokhapokha atakambirana ndi a ophthalmologist kuti tipewe kutaya mtima kwapakati. "
Konstantin, wazaka 42, wazachipatala, ku Moscow: "Wessel Douay f adziyambitsa yekha ngati njira yabwino yotsatirira. Ubwino wodziwikiratu ndikuti umatha kuthandizidwa ngakhale ndi anthu odwala matenda ashuga. Komanso, kuchuluka kwa zovuta ndizochepa. Kuphatikiza apo, amagwira bwino pakuchiza matenda a atherosulinosis, varicose veins and thromboangiitis "Ngakhale atalandira chithandizo chamanthawi yayitali, mankhwalawo ndiotetezeka kwathunthu. Choyipa chokha ndikuti palibe mafanizo omwe kuthekera kwake kungatsimikiziridwe."
Ndemanga za Odwala
Olga, wazaka 26, Saratov: "Mwamuna wanga sanathe kukhala ndi pakati. Palibe chomwe chidatulukira ndi IVF. Pambuyo pa kulephera kwina, dokotala wazachipatala adatumiza chithandizo kwa a hematologist. Tidapeza zovuta za magazi. Dotolo adayambitsa maphunziro a Wessel Douay F. Poyamba tidachita mantha ndi mtengo wake - chifukwa cha 4 mapaketi azamankhwala adapereka ma ruble 3,000, koma zidathandiza.Zowongolera zidasintha, ndidatha kutenga pakati.
Koma pa sabata la 20, Kafukufuku wa Doppler adatsimikiza kuti mwana ali ndi vuto la oxygen. Dokotala adamulamula kuti atenge kapisozi kwa milungu itatu. Kumapeto kwa maphunzirowa, adadutsa mayeso onse ofunikira ndikuyambiranso Doppler. Zonse zakhala zabwinobwino. "
Valentina, wazaka 52, Penza: "Wessel Douay f adayikidwa ndi a nephrologist. Kwa zaka zambiri ndakhala ndikudwala matenda a shuga, omwe amakhala ndi zovuta m'm impso. Mankhwalawa amathandizira magwiridwe antchito a impso ndipo amakhala ndi zotsatira zabwino m'mitsempha yamagazi. "zotupa za pakhungu. Amakanda ndipo sanapumule. Dotolo adalangiza kuti muchepetse mankhwalawo. Pakapita kanthawi, zotupa zimachoka ndipo zonse zidayambiranso."
Peter, wazaka 60, Kazan: "Ndili ndi vuto lam'mitsempha yama varicose yotsika kwambiri. Kutupa kokhazikika komanso kulemera kwambiri m'miyendo. Dotoloyo adadziwonetsa kamodzi pachaka kuti alowetse mankhwalawa mwamphamvu. Njira yochizira ndi masiku 10. Patatha jakisoni 10 zimayamba kukhala zosavuta. kuti sinditha kuyimitsa jakisoni. Nthawi zonse pamakhala mabowo pamalo opangira jakisoni komanso kumva kutentha kwamphamvu. Ndikupangira mankhwalawa kwa aliyense amene akufuna kuti athetse msanga zizindikiro zopweteka za mitsempha ya varicose. "
