Mankhwala Moxifloxacin: malangizo ntchito

Moxifloxacin ndi mankhwala antimicrobial, kukula kwake ndi mwatsatanetsatane mankhwala.

Dzinalo Losayenerana

Moxifloxacin. Dzina lazamalonda loperekedwa ndi Moxifloxacin.

Moxifloxacin ndi mankhwala antimicrobial.

ATX

J01MA14.

Kutulutsa mafomu ndi kapangidwe kake

Chofunikira chachikulu ndi moxifloxacin. Chidachi chimapezeka m'mitundu itatu.

Mapiritsi

Zothandizira pazinthu za piritsi ndi microcrystalline cellulose, lactose monohydrate, iron oxide, magnesium stearate, titanium dioxide. Kuchuluka kwa zinthu zogwira ndi 400 mg piritsi limodzi.

Zothandizira pazinthu za piritsi ndi microcrystalline cellulose, lactose monohydrate, iron oxide, magnesium stearate, titanium dioxide.

Madontho

Mawonekedwe amaso ali ndi mawonekedwe ofanana ndi njira yothetsera kukoka. Kuchuluka kwa gawo lalikulu ndi 400 mg.

Njira Zothetsera

Kuchuluka kwa moxifloxacin hydrochloride ndi 400 mg, zothandizira ndi sodium chloride, hydrochloric acid, madzi a jekeseni.

Njira yamachitidwe

Mankhwalawa ali ndi antibacterial ndi bactericidal momwe tizilombo toyambitsa matenda. Kuletsa kwa ntchito ya bakiteriya kumatheka chifukwa chakuti chinthu chachikulu chogwira ntchito chimalepheretsa maapoziatrogen, zomwe zimayambitsa kusokonezeka kwa kaphatikizidwe ka iwo mwa ma cellular. Mankhwala amaletsa njira za kukula ndi kubereka kwa microflora ya pathogenic, amalepheretsa magawo a bakiteriya.

Mankhwalawa ali ndi antibacterial ndi bactericidal momwe tizilombo toyambitsa matenda.

Mankhwalawa ali ndi bactericidal motsutsana ndi microflora ya pathogenic, yomwe imatha kukana kwambiri maantibayotiki ambiri ndi mankhwala ochokera ku gulu la macrolide, methicillin. Ntchito ya in vitro imatheka pokhudzana ndi gram-positive (kuphatikiza Staphylococcus cohnii ndi Streptococcus anginosus) ndi mabakiteriya osagwiritsa ntchito gramu, pamavuto a anaerobes ndi ma microorganisms okhala ndi mwayi wambiri wotsutsana ndi ma macrolide antibayotiki (mwachitsanzo, Streptococcus pneumoniae ndi Haemophilus fuluwenza).

Pharmacokinetics

Mlingo wa bioavailability pafupifupi 91%. Kuzindikira kwakukulu m'magazi kumafika ola limodzi pambuyo pokhazikitsa yankho. Zomwe zimapangidwira mankhwalawa atangolowa m'magazi, zimagawidwa mu minofu yofewa, momwe mulumikizidwe wawo ndi mapuloteni amwazi ndi 45%. Hafu ya moyo wa mankhwala kuchokera mthupi ndi maola 12.

Mukamagwiritsa ntchito mulingo woyenera wa mankhwalawa, pafupifupi 20% imachotsedwa mu impso ndi mkodzo, ndipo pafupifupi 26% ndi ndowe.

Zizindikiro zogwiritsidwa ntchito

Amagwiritsidwa ntchito ngati mankhwala odziyimira pawokha kapena panjira yovuta ya zinthu zotsatirazi:

• bakiteriya matenda a kumaliseche ndi kwamikodzo dongosolo (vaginitis, salpingitis, endometritis mu akazi, prostatitis mwa amuna);
• matenda kupuma: sinusitis mu mawonekedwe ovuta, chibayo zosiyanasiyana etiologies, alveolitis, ulesi bronchitis;
• matenda a pakhungu chifukwa cha malowedwe a tizilombo tizilombo;
• chifuwa chachikulu
• matenda opatsirana pogonana - chlamydia, ureaplasmosis, gonorrhea.

Moxifloxacin amagwiritsidwa ntchito ngati matenda a bakiteriya a ziwalo zoberekera ndi kwamikodzo.

Moxifloxacin amagwiritsidwa ntchito kupuma matenda.

Moxifloxacin amagwiritsidwa ntchito poteteza khungu.

Monga prophylaxis, mankhwalawa amagwiritsidwa ntchito pamene mycoplasmosis ikupezeka motsutsana ndi maziko a chitetezo chamthupi chodandaula. Pankhaniyi, mankhwala okhazikika amathandizira kuchepetsa kubwereranso. Mankhwala amatchulidwa pambuyo opaleshoni ntchito ngati njira kupewa mavuto.

Kwa amuna, mankhwalawa amagwiritsidwa ntchito pochiza matenda a prostatitis oyambira bakiteriya, komanso milandu otsatirawa:

• kuchepa mphamvu kapena kusowa kwake mukamamwa mankhwala ena;
• kukhalapo kwa microflora ya pathogenic, yomwe nthawi ya mankhwala okhala ndi quinolones siziwonongeka chifukwa chotsutsa kwambiri;
• kukhalapo kwa akatswiri angapo a etiology;
• pafupipafupi matenda;
• mkulu Mwina kusintha kwa prostatitis aakulu mawonekedwe.

Kwa amuna, mankhwalawa amagwiritsidwa ntchito pochiza matenda a prostatitis a bacteria.

Nthawi zambiri, mankhwalawa amagwiritsidwa ntchito ngati chida chowonjezera pothandizira matenda a bakiteriya oyambira.

Contraindication

Sizoletsedwa kulandira anthu ndi:

• tsankho limodzi pazigawo za mankhwala;
• kuchepa kwa lactose;
• colitis ya mtundu wa pseudomembranous;
• magawo akulu a impso kulephera;
• khunyu;
• Misewu yambiri yolumikizidwa;
• pachimake siteji ya myocardial infarction.

Sizoletsedwa kutenga anthu omwe ali ndi colitis ya mtundu wa pseudomembranous.

Sizoletsedwa kutenga anthu omwe ali ndi khunyu.

Sizoletsedwa kutenga anthu omwe ali ndi gawo loyipa la infracation ya myocardial.

Ndi zoletsedwa kumwa mankhwalawa odwala osaposa zaka 18 komanso kulekerera maantibayotiki a gulu la fluoroquinolone ndi gulu la quinolone.

Ndi chisamaliro

Kupezeka kwa hypoglycemia ndi kuphwanya wachibale kutenga Moxifloxacin. Mankhwalawa amatchulidwa pokhapokha ngati phindu likamamwa limaposa chiopsezo chovuta. Mochenjera ndi kusintha kwa mlingo wa munthu, mankhwalawa amathandizidwa ndi mtima wa arrhythmias (arrhythmias), hypokalemia.

Chisankho cha munthu payekha chikufunika pochiza anthu opatuka pakugwira ntchito kwamkati wamanjenje, chifukwa pali kuthekera kwa kugwidwa kwa minofu ndikugwedezeka.

Zizindikirozi zikachitika, muyenera kudziwitsa dokotala wanu za izi ndikusiya kumwa Moxifloxacin.

Kodi kutenga moxifloxacin?

Njira yothetsera kulowetsedwa kwa mtsempha wa magazi (400 mg) iyenera kuthandizidwa pang'onopang'ono, kwa ola limodzi. Pafupipafupi mankhwala osokoneza bongo patsiku ndi 1 nthawi. Milandu yayikulu yamankhwala yokhala ndi chithunzi chodziwika bwino, mukakhala ndi zotsatira zabwino, mankhwalawa amaperekedwa kudzera mwa catheter.

Kutalika kwa nthawi ya maphunzirowa ndi kwamodzi:

1. Chithandizo cha chibayo chomwe chinapezeka m'magulu: Mlingo ndi 400 mg, njira ya mankhwalawa imachokera ku sabata 1 mpaka 2.
2. Matenda opatsirana a pakhungu: kuyambira masiku 7 mpaka 21. Mlingo wokhazikika ndi 400 mg.
3. Chithandizo cha matenda ophatikizika kwambiri: kuyambira masiku 5 mpaka milungu iwiri.

Njira yothetsera kulowetsedwa kwa mtsempha wa magazi (400 mg) iyenera kuthandizidwa pang'onopang'ono, kwa ola limodzi.

Kutenga mapiritsi a Moxifloxacin - piritsi 1 patsiku.

Kutalika kwa mankhwala kumatsimikiziridwa ndi dokotala;

Kumwa mankhwala a shuga

Mlingo umatsimikiziridwa payekha ndi dokotala wopita. Munthawi yonse ya mankhwala a Moxifloxacin odwala omwe ali ndi matenda ashuga, ndikofunikira kuwunika pafupipafupi kuchuluka kwa shuga m'magazi. Malinga ndi kuchuluka kwazachipatala, mwa anthu omwe ali ndi vutoli pomwe akumamwa Moxifloxacin, pakhoza kukhala kupatuka mu labotale ya glucose m'magazi.

Mankhwala ayenera kumwedwa mosamala, kumatha kupangitsa matenda a hyperglycemia kapena hypoglycemia.

Zotsatira zoyipa

Nthawi zambiri kugwiritsa ntchito mankhwalawa kwakanthawi, pamakhala kuphwanya boma komanso kugwira ntchito kwa microflora yopindulitsa - kukulitsa kwa candidiasis ya mkamwa kapena ukazi. Maonekedwe a dysbiosis ndi otheka. Zotsatira zoyipa zamunthu wamba: kupweteka pachifuwa, pelvis ndi m'munsi kumbuyo, kukula kwa photosensitivity.

Nthawi zambiri pogwiritsa ntchito mankhwalawa kwa nthawi yayitali, dysbacteriosis imawoneka.

Matumbo

Kuchepetsa mseru komanso kusanza, kusokonezeka kwa chifuwa (kutsekula m'mimba), kupweteka pamimba, kukulira kapena kusowa kudya kwathunthu. Pafupipafupi - kudzimbidwa, gastritis, stomatitis, colitis.

Hematopoietic ziwalo

Nthawi zina, kuchepa magazi, leukopenia imawonekera. Kuchuluka kwa kuchuluka kwa prothrombin thunthu.

Pakati mantha dongosolo

Pali matenda a chizungulire komanso kupweteka kwa mutu pafupipafupi, chisokonezo, kunjenjemera, vuto la kugona (kusowa tulo), kusokonezeka kwa kayendedwe ka kayendedwe. Mavuto olankhula ndi chidwi, amnesia osakhalitsa, chitukuko cha zotumphukira zamtundu wa neuropathy sichitha.

Nthawi zina mutamwa mankhwalawa, mutu umayamba.

Kuchokera ku minculoskeletal system

Odwala ena amakhala ndi myalgia ndi arthralgia. Minyewa yolimbitsa thupi, kufooka kwa minofu sikumawonedwa kawirikawiri. Ngakhale chocheperako kwambiri ndicho kupuma kwa tendon, nyamakazi.

Kuchokera ku genitourinary system

Kuwonongeka kwa impso, kukula kwa aimpso kulephera.

Kuchokera pamtima

Matenda oopsa a ubongo amayamba, tachycardia, angina pectoris, kugunda kwa mtima.

Matupi omaliza

Nthawi zina ming'oma, kuyabwa pakhungu, zotupa ndi redness zimawonekera.

Nthawi zina, mutatha kumwa mankhwalawa, ming'oma imawoneka.

Malangizo apadera

Pambuyo pa Mlingo woyamba wa mankhwalawa, kuwonetseredwa kwa zizindikiro zam'mbali ndikotheka. Ngati ziwengo zachititsa kuti anaphylactic asinthe, mankhwala ayenera kuyimitsidwa nthawi yomweyo. Kukula kocheperako kwa ziwonetsero za thupi lawo sikutanthauza kuti munthu athetse mankhwalawa, tikulimbikitsidwa kuti muchepetse mlingo wa 250 mg. Momwe zilabwinizo zimatha, mlingo umayamba kuchuluka.

Jakisoni wa mu mnofu samaperekedwa. Mothandizidwa ndi catheter, kulowetsedwa njira zimawonjezeredwa kwa mankhwalawa, omwe amatha kusungidwa kwa tsiku limodzi. Popanga mankhwala ovuta, mankhwala onse ayenera kumwedwa mosiyanasiyana.

Kuyenderana ndi mowa

Kumwa zakumwa zoledzeretsa panthawi yopereka chithandizo koletsedwa.

Kumwa zakumwa zoledzeretsa panthawi yopereka chithandizo koletsedwa.

Zokhudza mphamvu pakuwongolera njira

Popeza kuopsa kwa zotsatira zoyipa mukamamwa Moxifloxacin, monga chizungulire, kuchepa ndende ndikuchepetsa kukhudzika kwa psychomotor, tikulimbikitsidwa kuti tisayendetse ntchito ndikugwiritsa ntchito njira zovuta.

Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere

Izi ndi zoletsa kumwa mankhwalawa. Ngati ndi kotheka, gwiritsani ntchito mankhwalawa panthawi yoyamwitsa, yoyamwitsa iyenera kuyimitsidwa.

Kupangira Moxifloxacin kwa ana

Osati kwa ana osachepera 33 kg. Nthawi zina, muyezo Mlingo ndi 400 mg wodziwika ndi chithunzi cha matendawa. Ndi chiwonetsero chokwanira cha matendawa komanso vuto la zovuta zakumwa kwa Moxifloxacin, mlingo wa mankhwalawa umachepa.

Moxifloxacin sanalembedwe kwa ana olemera zosakwana 33 kg.

Gwiritsani ntchito mu ukalamba

Mlingo ndi nthawi ya maphunzirowa amasankhidwa kwa wodwala aliyense pamaso pa matenda oyipa payekhapayekha.

The ntchito aimpso kuwonongeka

Kusintha kwa Mlingo kwa odwala omwe ali ndi matenda a impso, kuphatikizira anthu omwe akudwala hemodialysis, sikofunikira.

Gwiritsani ntchito ntchito yolakwika ya chiwindi

Mankhwalawa amatengedwa malinga ndi malingaliro omwe aperekedwa pakutsatira komanso kutalika kwa njira yothandizira achire.

Bongo

Pogwiritsa ntchito Moxifloxacin kwambiri, kuwonjezeka mwamphamvu kwa mawonetseredwe a zizindikiro za mbali ndizotheka. Njira zothandizira woyamba amasankhidwa poganizira zovuta za momwe wodwalayo alili. Mankhwalawa ndi chizindikiro. Nthawi zambiri, wodwala ndi wokwanira kuti atenge adsorbent - yodziyimira kaboni.

Malinga ndi kafukufuku, mankhwalawa samayenderana ndi kulera kwapakamwa.

Kuchita ndi mankhwala ena

Malinga ndi kafukufuku, mankhwalawa samayenderana ndi kulera kwapakamwa, Warfarin, Probenecid, Glibenclamide. Njira yothetsera mankhwala siyenera kusakanikirana ndi mayankho ena.

Kuphatikiza kophatikizidwa

Ndi zoletsedwa kutenga Moxifloxacin ndi:

• antiarrhythmics of IA, kalasi III;
• antipsychotic mankhwala;
• tetracyclic antidepressants;
• antimicrobial agents (saquinavir, erythromycin);
• antihistamines (Misolastine, Astemizole).

Kukhazikika kwa moxifloxacin ndi erythromycin sikuletsedwa.

Ndi zoletsedwa kumwa Moxifloxacin ndi mankhwala a antipsychotic.

Kugwiritsa ntchito nthawi yomweyo kwa Moxifloxacin okhala ndi ma tidacclic antidepressants ndi koletsedwa.

Osavomerezeka kuphatikiza

Kuphatikiza ndi thiazide diuretics ndizoletsedwa. Ndiosafunika panthawi ya mankhwala ndi Moxifloxacin kuyika kuyeretsa enemas ndi mankhwala ofewetsa tuvi tolimba.

Kuphatikiza komwe kumafunikira kusamala

Chenjezo kuphatikiza ndi mankhwalawa:

• piritsi la didanosine;
• kukonzekera kokhala ndi aluminiyamu ndi magnesium;
• Maantacid - kupuma kwa maola osachepera 6 ndikofunikira.

Analogi

Mankhwala omwe ali ndi vuto lofananalo (ma cellacological synonyms): Moxifloxacin Canon, Ofloxacin, Alvogen, Moxin, Tevalox.

Kupita kwina mankhwala

Chinsinsi chimafunikira ku Latin kapena Russian.

Kodi ndingagule popanda kulandira mankhwala?

Popanda mankhwala, mankhwalawo sadzagulitsidwa ku pharmacy.

Mtengo wa moxifloxacin

Mtengo wamankhwala amachokera ku ma ruble a 360.

Zosungidwa zamankhwala

Sungani kutentha kwa 8 mpaka 25 ° C. Mankhwalawa mu ampoules amaletsedwa kusunga mufiriji. Mothandizidwa ndi kutentha kochepa, mvula imawoneka, kupezeka kwake komwe kumawonetsa kuti yankho silingagwiritsidwe ntchito.

Kuti mugule mankhwalawa, muyenera kupatsidwa mankhwala mu Latin kapena Russian.

Tsiku lotha ntchito

Osapitirira zaka 2.

Wopanga

India, MacLeods Pharmaceuticals Limited.

Ndemanga za moxifloxacin

Madokotala

Eugene, wazaka 51: “Moxifloxacin wadziwikiratu pochiza matenda a bakiteriya. Amathetsa mwachangu matendawa, kuwononga mabakiteriya. Pothandizidwa ndi prostatitis, iyenera kugwiritsidwa ntchito limodzi ndi mankhwala ena.”

Ksenia, wazaka 44, yemwe ndi dokotala wamkulu: "Pneumonia, chithandizo cha Moxifloxacin ndichofunika kwambiri. Ngakhale mankhwalawa amagwiritsidwa ntchito limodzi ndi mankhwala ena, amathandizira kwambiri microflora ya pathogenic ndipo amachepetsa zizindikiro za matendawa."

Odwala

Dmitry, wazaka 43, Odessa: "Anazindikira kuti ali ndi vuto la prostatitis. Dokotala nthawi yomweyo adamuuza Moxifloxacin. Anamwa mankhwalawa kwa masiku 10, patatha masiku ochepa ululuwo utapita. Pambuyo pa chithandizo chomwe adapereka mayeso, zonse zili bwino."

Alexandra, wazaka 41, Tomsk: "Ziphuphu zochizira m'masiku 10, anaikapo jakisoni wa Moxifloxacin m'masiku atatu oyamba, kenako nkuyamba kumwa mapiritsi.

Andrey, wazaka 29, Krasnoyarsk: "Anachiza Moksifloxacin ndi matenda apakhungu. Masiku 5 - otsika ndi njira, masiku - mapiritsi 10. Atatha kumwa, mkhalidwewo unatha, ndipo matendawo anatha. mankhwala othandiza. "