Amix ndi mankhwala ochizira ovuta a 2 shuga. Zimathandizira pakupanga bwino insulin ndi maselo a pancreatic. Nthawi yomweyo, chidwi cha minofu kuti chikhale ndi insulin yowonjezereka chikuwonjezeka, ndipo kumasulidwa kwake kumakhala kwabwino.
Dzinalo Losayenerana
Mankhwala a INN: Glimepiride.
Mankhwala amathandizira kupanga bwino insulin ndi maselo a pancreatic.
ATX
Code ya ATX: A10BB12.
Kutulutsa mafomu ndi kapangidwe kake
Mankhwalawa amapezeka piritsi. Dzina lenileni la mankhwalawa limatengera kuchuluka kwa mankhwala omwe amapezeka piritsi limodzi.
Zomwe zimagwira ndi glimepiride. Wothandiza:
- povidone;
- cellulose;
- ena lactose;
- silika;
- magnesium wakuba;
- iron oxide;
- utoto.
Amix-1 ili ndi 1 mg ya glimepiride. Mapiritsi ndi chowulungika ndi pinki. Amix-2 - zobiriwira. Ili ndi 2 mg yogwira ntchito. Amix-3 ili ndi 3 mg ya glimepiride. Mapiritsi achikasu. Amix-4 ndi mtundu wamtambo, ali ndi 4 mg pazinthu.
Mapiritsi onse ali ndi matuza apadera a ma 10 ma PC. m'modzi aliyense. Pa mtolo wa makatoni pakhoza kukhala 3, 9 kapena 12 mwa matuza awa.
Mukamagwiritsa ntchito mankhwalawa, kumva kwa insulin pancreatic zimakhala.
Zotsatira za pharmacological
Mankhwala ali ndi hypoglycemic. The yogwira mankhwala - glimepiride - amatanthauza sulfonylurea zotumphukira. Chimalimbikitsa kutsegula kwa insulin katulutsidwe ndi maselo apakati a pancreatic. Pankhaniyi, kutulutsidwa kwa insulin kumachitika mwachangu, ndipo chidwi cha minyewa ya pancreatic kwa icho chimakulanso.
Pharmacokinetics
The bioavailability ndi kuthekera kumangiriza ku mapuloteni opanga pafupifupi 100%. Chakudya chochepa kwambiri chimalepheretsa kuyamwa kwa mankhwalawo m'mimba. Kwambiri ndende yogwira ntchito m'magazi imawonedwa maola angapo mutatha piritsi. Metabolism imachitika makamaka m'chiwindi. Chidacho chimaphatikizika limodzi ndi mkodzo komanso kudzera m'matumbo patatha maola 6 atatha kulowa thupi.
Zizindikiro zogwiritsidwa ntchito
Mankhwalawa amagwiritsidwa ntchito pothana ndi matenda a shuga a mtundu wachiwiri, makamaka muzochitika zomwe shuga ya magazi singathe kuwongolera pakudya, kuwonda komanso kuyesetsa mwamphamvu.
Mankhwalawa amagwiritsidwa ntchito pochiza matenda amishuga amtundu wa 2 pomwe shuga yamagazi sangathe kuwongolera pakudya.
Contraindication
Pali zoletsa kugwiritsa ntchito mankhwalawa:
- mtundu 1 matenda a shuga;
- ketoacidosis;
- matenda a shuga;
- nthawi ya bere ndi kuyamwitsa.
Izi zotsutsana zonse ziyenera kukumbukiridwa musanayambe mankhwala. Wodwala adziwitsidwe kudziwa zoopsa zomwe zingachitike ndi zovuta zake.
Ndi chisamaliro
Mosamala kwambiri, imwani mapiritsi a anthu omwe ali ndi chidwi chachikulu ku zinthu zina za mankhwalawo, ku zotumphukira zina za sulfanilamide.
Momwe mungatenge Amix
Mlingo wa mankhwalawa umatsimikiziridwa ndi zotsatira za mayeso. Kupambana kwa chithandizo kumatengera kutsatira zakudya zapadera ndikuwunika mayeso a magazi ndi mkodzo nthawi zonse.
Poyamba, 1 mg patsiku ndizomwe zimayikidwa. Mlingo womwewo umagwiritsidwa ntchito pokonza mankhwala. Ngati zotsatira zomwe mukufuna sizingatheke, mlingowo umakulitsidwa mpaka 2, 3 kapena 4 mg patsiku lililonse masabata awiri. Mlingo waukulu kwambiri umatha kufika pa 6 mg pa tsiku. Koma ndibwino kuti musapitirire 4 mg.
Kupambana kwa chithandizo kumatengera kutsatira zakudya zapadera ndikuwunika mayeso a magazi ndi mkodzo nthawi zonse.
Kwa odwala omwe samalipira zovuta za carbohydrate metabolism, chithandizo chowonjezera cha insulin chimangoyambika pazovuta kwambiri. Kuti muchite izi, gwiritsani ntchito ma cartridge apadera ndi mankhwala osokoneza Mlingo wa 125 mg. Zikatero, chithandizo ndi Amix chimapitiliridwanso pamankhwala omwe amaperekedwa poyamba, ndipo mlingo wa insulin pawokha umakulitsidwa pang'ono ndi pang'ono.
Chithandizo cha matenda ashuga
Nthawi zambiri amalimbikitsidwa kumwa tsiku lililonse kamodzi m'mawa. Ngati wodwalayo adayiwala kumwa piritsi, ndiye kuti nthawi yotsatira simuyenera kuwonjezera mlingo.
Mankhwala, kuchepa kwa insulin kumawonjezera ndipo kufunika kwa glimepiride kumachepa. Popewa kukula kwa hypoglycemia, ndibwino kuti muchepetse mankhwalawo kapena pang'onopang'ono kusiya kumwa. Pochizira matenda amishuga amtundu wa 2, kuphatikiza Amix ndi insulin yoyenera kumakonda kugwiritsidwa ntchito.
Zotsatira zoyipa
Zizindikiro za hypoglycemia nthawi zina zimayamba. Chodziwika pakati pawo:
- kusanza komanso kusanza;
- kupweteka mutu komanso chizungulire;
- kugona
- mphwayi
- kuwonjezeka kwamphamvu kwa chikhumbo.
Kuphatikiza apo, chidwi cha anthu akusintha. Matenda opatsirana ndi kugwedezeka kumawonekera. Munthu amakhala ndi nkhawa, amakhala wosakwiya msanga. Kusowa tulo kumawonekera, kuwonongeka kwina. Nthawi zambiri pamakhala kuchuluka kwa sodium m'magazi.
Matumbo
Kusanza, kusanza, kupweteka kwam'mimba, kusintha kwa chiwindi, kuwonjezeka kwake kwa enzymatic.
Hematopoietic ziwalo
Kumbali ya ziwalo za hemopoietic, kuphwanya kwambiri kumawonedwa. Nthawi zina, thrombocytopenia, agranulocytosis, kuchepa magazi ndi leukopenia amawonekera.
Kuchokera pakuwonekera
Kumayambiriro kwenikweni kwa mankhwalawa, kusokonezeka kwakanthawi kochepa kumatha kuchitika, komwe kumachitika chifukwa cha kulumpha kowopsa m'magazi a magazi.
Kuchokera pamtima
Nthawi zambiri ochepa matenda oopsa, tachycardia, angina osakhazikika komanso arrhasmia yayikulu imayamba. Odwala ena amakhala ndi bradycardia mpaka kuthedwa nzeru.
Matupi omaliza
Nthawi zina, thupi limakhala kuti siligwirizana. Odwala amadziwa mawonekedwe a zotupa pakhungu, kuyabwa, urticaria. Kukula kwa edema ya Quincke ndi mtundu wa anaphylactic sikuti pazokha. Ngati zizindikiro zoopsa ngati izi zikuwoneka, chithandizo chiyenera kuyimitsidwa mwachangu.
Malangizo apadera
Zizindikiro za hypoglycemia zitha kuchitika kuyambira koyambirira kwenikweni kwa mankhwalawa, chifukwa chake, muyezo wothandizira uyenera kuyang'aniridwa mosamala. Kupititsa patsogolo kuchuluka kwa shuga m'magazi kumathandizira kuti asakhale ndi vuto la kuperewera kwa thupi, kulephera kutsatira zakudya zomwe wapatsidwa komanso kudya kudya pafupipafupi.
Kuyenderana ndi mowa
Simungathe kuphatikiza zakumwa zoledzeretsa ndi zakumwa zoledzeretsa. Zizindikiro za kuledzera pamenepa zimakulitsidwa kwambiri, mphamvu ya mankhwalawa pakukalamba kwamanjenje imakulitsidwa. Mphamvu ya hypoglycemic yogwiritsidwa ntchito ndi Amix siyowonekera.
Zokhudza mphamvu pakuwongolera njira
Panthawi yamankhwala, ndi bwino kukana kuyendetsa galimoto nokha. Mankhwalawa amakhudza chidwi cha anthu, amathandiza kupewetsa kukhudzika kwa ma psychomotor kofunikira mwadzidzidzi.
Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere
Simungagwiritse ntchito mankhwalawa panthawi yonse yobala mwana. Changu chogwira ntchito chimalowa mwachangu zotchinga za placenta ndipo zimatha kupangitsa mapangidwe a fetal. Ngati pakufunikira chithandizo, mayi woyembekezera amapititsidwa ku mulingo wochepa wa insulin.
Ngati pakufunika kuchitira insulin mankhwala, mkazi ndi bwino kusiya kuyamwitsa.
Kulembera Amix kwa ana
Mankhwala sagwiritsidwa ntchito ngati ana.
Pochiza Amix ndi odwala okalamba, muyeso wochepa wa mankhwalawo ndi mankhwala.
Gwiritsani ntchito mu ukalamba
Pochiza Amix ndi odwala okalamba, mulingo wochepetsetsa wa mankhwalawa umaperekedwa, chifukwa zimakhudza ntchito ya ziwalo zambiri ndi machitidwe. Akuluakulu amatha kutengera zovuta pamtima, motero muyenera kuyang'anira mosamala kusintha kulikonse komwe kumachitika wodwalayo akamalandira chithandizo.
The ntchito aimpso kuwonongeka
Samalani mukamagwiritsa ntchito mapiritsi pamaso pa impso. Ndikwabwino kusankha mlingo wocheperako wolepheretsa kulephera kwa impso. Zonse zimatengera chilolezo cha creatinine. Zizindikiro zake zochulukirapo, kuchuluka kwa mankhwalawo kungafunikire.
Gwiritsani ntchito ntchito yolakwika ya chiwindi
Yang'anani kusintha kulikonse pakuyesedwa kwa chiwindi. Mlingo waukulu umathandizira kukula kwa chiwindi. Pankhaniyi, mlingo uyenera kuchepetsedwa. Ngati wodwalayo akupitilirabe, ndi bwino kusiya kumwa Amix.
Bongo
Ngati bongo wambiri, hypoglycemia imayamba, Zizindikiro zake zomwe zimatha kukhala kwa maola angapo mpaka masiku angapo. Chowonekera:
- nseru
- kusanza
- mutu
- kupweteka kwa epigastric;
- olimba;
- kuwonongeka kwamawonekedwe;
- kusowa tulo
- kugwedezeka
- kukokana.
Pankhani ya mankhwala osokoneza bongo, kutsuka kwa m'mimba kumachitika.
Pankhaniyi, wodwala ayenera kuchipatala.
Gastric lavage ndi detoxification mankhwala amachitika. Onetsetsani kuti mukugwiritsa ntchito mayankho omwe ali ndi shuga wambiri. Mankhwala ena ndiwowonekera.
Kuchita ndi mankhwala ena
Kugwiritsa ntchito Amix ndi mankhwala ena kumatha kubweretsa kulimbikitsidwa kosafunikira kapena kufooka kwa mphamvu ya hypoglycemic ya chinthu. Kupatula kokha ndi mankhwala a immunomodulatory.
Kuphatikiza kophatikizidwa
The munthawi yomweyo kuperekedwa kwa Amix ndi mankhwala amatsutsana:
- phenylbutazone;
- insulin;
- salicylic acid;
- anabolic steroids;
- mahomoni ogonana amuna;
- anticoagulants.
The munthawi yomweyo Amix ndi Insulin ali contraindicated.
Ndi kuphatikiza pamodzi, hypoglycemia ikhoza kuchitika.
Osavomerezeka kuphatikiza
Kuchepa kwa mphamvu ya mankhwalawa kapena kuchuluka kwa shuga m'magazi kumatsutsidwa ndi kayendetsedwe kake ka munthawi yomweyo ndimankhwala otere:
- estrogen;
- progesterone;
- okodzetsa;
- glucocorticosteroids;
- Adrenaline
- nicotinic acid;
- mankhwala othandizira;
- barbiturates.
Kuchitikirana kumatha kukhala kwadzidzidzi, chifukwa chake muyenera kumwa mankhwalawa mosamala kwambiri.
Iwo ali osavomerezeka kuphatikiza mankhwalawa ndi mankhwala omwe ali ndi diuretic.
Kuphatikiza komwe kumafunikira kusamala
Kugwiritsa ntchito nthawi yomweyo kwa Amix ndi olimbana ndi H2-receptor, mapuloteni ena a plasma, komanso b-blockers ndi Reserpine kumapangitsa kutsika kwa glucose. Mankhwala omwe adatchulidwa amatha kuphimba zizindikiro za adrenergic matenda, omwe amachokera ku hypoglycemia.
Analogi
Pali ma analogi angapo omwe ali ofanana ndi mankhwalawa pokhudzana ndi yogwira ntchito komanso yothandizira. Zodziwika kwambiri pakati pawo ndi:
- Amaryl;
- Amapyrid;
- Glairie
- Glimax;
- Glimepiride;
- Dimaril;
- Guwa
- Perinel.
Mankhwalawa ndi osavuta kupeza m'masitolo, ndipo ndi otsika mtengo.
Glimax imatha kukhala ngati analogue ya mankhwala.
Amixa Mankhwala Olephera Kupezeka
Mankhwala amaperekedwa kuchokera ku malo ogulitsa mankhwala okha ndi mankhwala apadera kuchokera kwa adokotala.
Mtengo
Masiku ano, mankhwala ndiosavuta kupeza m'masitolo. Popeza ikupezeka ndi mankhwala, sizingatheke kuigulanso muma pharmacies opezeka pa intaneti, chifukwa chake palibe deta pamtengo.
Mtengo wa analogues ku Russia umayambira ku ma ruble 170, ndipo ku Ukraine mankhwalawa amatenga 35 mpaka 100 UAH.
Sinthani malo osungira
Mankhwalawa amasungidwa pokhapokha choyambirira. Mu malo owuma komanso amdima, pa kutentha kwa mpweya osaposa + 30 ° C, kutali ndi ana aang'ono ndi ziweto.
Tsiku lotha ntchito
Alumali moyo wa mapiritsiwo ndi zaka 2 kuyambira tsiku lotulutsidwa lomwe lasonyezedwa pa zoyambitsidwa koyambirira.
Wopanga
Kampani yopanga: Zentiva, Czech Republic.
Umboni wa madokotala ndi odwala pa Amiks
Ndemanga za mankhwalawa samangokhala ndi madokotala okha, komanso ndi odwala ambiri.
Madokotala
Oksana, wazaka 37, endocrinologist, Saratov: "Nthawi zambiri ndimapereka mankhwala kwa odwala omwe ali ndi matenda a shuga. Ndemanga za iwo ndizosiyana. Ena amathandizanso, ena amakakamizidwa kuti abwererenso ku insulin. Mphamvu yake ndimankhwala abwino. Mwamaganizidwe abwinobwino ndi thupi, zochizira zimatheka mwachangu" .
Nikolai, wazaka 49, woweruza wazachipatala, a Kazan: "Ngakhale mankhwalawa amakonda kuperekedwa kwa odwala, siothandiza aliyense. Odwala ena amakhala ndi zovuta zosiyanasiyana zomwe zimapangitsa kuti asamamwe mankhwalawa. Pewani zovuta zosasangalatsa. "
Odwala
Petr, wazaka 58, ku Moscow: "Mankhwalawa adathandizira. Zinali zotheka kuchepetsa shuga m'magazi kwa nthawi yayitali. Koma kumayambiriro kwa chithandizo, mutu wanga udayamba kupweteka komanso ndikamadandaula pang'ono. Patadutsa masiku angapo, ndimadwaladwala."
Arthur, wazaka 34, Samara: "Mankhwalawa sanakwane. Patatha mapiritsi oyamba, zotupa pakhungu zinaonekera, ndinayamba kugona tulo, ndinakwiya kwambiri. Kuphatikiza apo, thanzi langali limadwaladwala. Dotolo adandiwuza kuti ndibwererenso kukamwa insulin."
Alina, wazaka 48, wa ku St. Petersburg: "Ndikhutira kwathunthu ndi mankhwalawa. Mankhwalawa ndi abwino. Ndidaigwiritsa ntchito m'malo mwa insulin yeniyeni. Sindimva chilichonse. Zotsatira zake zakhala zikuchitika kwa miyezi inayi."
