Mankhwala amatchulidwa kuwonjezera pa zolimbitsa thupi ndi kudya. Chidacho chimachepetsa shuga. Amagwiritsidwa ntchito pochiza matenda osokoneza bongo omwe amadalira shuga. Ndi mtundu 1 wa matenda osokoneza bongo satchulidwa.
Dzinalo Losayenerana
Repaglinide.
Kuzindikira kumachepetsa shuga.
ATX
A10BX02.
Kutulutsa mafomu ndi kapangidwe kake
Wopanga amatulutsa mankhwalawo ngati mapiritsi am'kamwa. Chosakaniza chophatikizacho ndi repaglinide mu kuchuluka kwa 0,5 mg, 1 mg ndi 2 mg. Katemera amakhala ndi miyala 20 kapena 60.
Zotsatira za pharmacological
Ili ndi vuto la hypoglycemic. Zimakhudza maselo ogwirira pancreatic beta. Imatseka njira za potaziyamu ndikuyambitsa kutsegulidwa kwa njira za calcium. Imalimbikitsa kutulutsa kwa insulin.
Pharmacokinetics
100% odzipereka kuchokera kumimba. Amamangidwa ndi mapuloteni ndi 98% ndipo imapangidwira m'chiwindi ndikupanga ma metabolites osagwira. Pambuyo mphindi 60, kuchuluka kwambiri kwa repaglinide mu madzi amwazi kumafika. Imafukusidwa mu ndulu ndi mkodzo pambuyo pa maola 5-6.
Mankhwalawa amatengedwa 100% kuchokera m'mimba.
Zizindikiro zogwiritsidwa ntchito
Mankhwala a hypoglycemic amaperekedwa kwa mtundu wachiwiri wa matenda osokoneza bongo (ngati sizingatheke kuti muzilamulira shuga mwanjira yogwira komanso zakudya zopatsa thanzi).
Contraindication
Ndi koletsedwa kuyamba kulandira mankhwalawa munthawi zotere:
- mtundu 1 shuga;
- mimba
- kuyamwitsa;
- ziwengo zosiyanasiyana za mankhwala;
- kuphwanya kagayidwe kazakudya chifukwa cha kuperewera kwa insulin (ketoacidosis);
- chikomokere ndi mtengo;
- kukhalapo kwa matenda, opaleshoni ndi zina zomwe zimafuna insulin.
Woopsa milandu, kuwonongeka chiwindi ndi impso, Diagnlinide si zotchulidwa.
Ndi chisamaliro
Kusamala munthawi ya mankhwala ndikofunikira kuti chiwindi chisagwidwe ndi impso (mofatsa pang'ono), kulephera kwaimpso, kuledzera komanso matenda achibadwa.
Mlingo wothandizila kudziwa
Imwani mankhwalawa mphindi 15-30 musanadye. Mlingo woyambirira ndi 0.5 mg. A.
Kuchepetsa thupi
Mu matenda a shuga, mankhwalawa akuwonetsa kuti amachepetsa thupi komanso amakhala ndi matenda a metabolism.
Chithandizo cha matenda ashuga
Mlingo amasankhidwa payekha kutengera mulingo wa shuga m'magazi. Ngati munathandizidwa kale ndi mankhwala a hyperglycemia, mutha kuyamba kumwa 1 mg patsiku. Kusintha kwa Mlingo kumachitika nthawi 1 m'masiku 7-14. Mlingo waukulu patsiku ndi 16 mg.
Imwani mankhwalawa mphindi 15-30 musanadye.
Zotsatira zoyipa za Diagninide
Mankhwalawa amatha kuyambitsa zovuta kuchokera kuzinthu zosiyanasiyana zamakanidwe.
Pa mbali ya gawo la masomphenyawo
Zowonongeka zitha kuchitika.
Kuchokera minofu ndi mafupa
Palibe zambiri zomwe zaperekedwa.
Matumbo
Kudzimbidwa, kugaya chakudya, kukhumudwa, ndi mseru. Kupweteka m'mimba kungachitike.
Hematopoietic ziwalo
Zochita za chiwindi michere sizichulukitsidwa kawirikawiri.
Chifukwa cha kumwa mankhwalawa, kudzimbidwa nthawi zina kumachitika.
Pakati mantha dongosolo
Kutopa, thukuta, kunjenjemera zimadziwika.
Kuchokera kwamikodzo
Palibe zambiri zomwe zaperekedwa.
Kuchokera ku kupuma
Palibe zambiri zomwe zaperekedwa.
Kuchokera pamtima
Mankhwala angayambitse kukula kwa pachimake coronary syndrome.
Pa mbali ya chiwindi ndi biliary thirakiti
Kugwira ntchito kwa chiwindi sikumveka bwino.
Pambuyo kumwa mankhwalawa, kugwira ntchito kwa chiwindi nthawi zina kumavuta.
Kuchokera kumbali ya kagayidwe
Nthawi zambiri, hypoglycemia imayamba (kuthamanga kwa shuga). Potere, mkhalidwe wodwala umadalira mlingo, kuchuluka kwa ena othandizira a hypoglycemic ndi zakudya.
Matupi omaliza
Chitetezo cha mthupi chimayambitsa hypersensitivity (kuyabwa, khungu, zotupa).
Zokhudza mphamvu pakuwongolera njira
Mankhwala amakhudza kuthekera kwazomwe zimayang'ana ndikuwongolera njira.
Malangizo apadera
Chiwopsezo cha kukhala ndi hypoglycemia chimawonjezeka ndikusagwirizana ndi zakudya, kusala, kumwa mowa komanso kupitirira muyeso wovomerezeka. Ndikofunikira kuyendetsa kuchuluka kwa shuga m'magazi am'magazi panthawi ya mankhwala. Kuyambapo ndi mlingo wocheperako ndikofunikira ndikulimbitsa thupi komanso malingaliro.
Chiwopsezo cha kukhala ndi hypoglycemia chimawonjezeka ngati zakudya sizitsatiridwa.
Gwiritsani ntchito mu ukalamba
Palibe chidziwitso pakugwira bwino ntchito komanso chitetezo kwa okalamba. Okalamba okalamba omwe afika zaka 75 zakubadwa.
Kupatsa ana
Mpaka azaka 18, mankhwalawa sanalembedwe.
Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere
Amayi oyembekezera sayenera kumwa mankhwalawa. Kwa nthawi yamankhwala, ndikofunikira kusiya kuyamwitsa.
The ntchito aimpso kuwonongeka
Odwala omwe ali ndi vuto laimpso ayenera kusamala posankha mlingo.
Gwiritsani ntchito ntchito yolakwika ya chiwindi
Pankhani ya kufatsa kwapafupipafupi, mankhwalawa ayenera kuyikidwa ndi dokotala. Woopsa milandu, mankhwalawo saloledwa.
Odwala omwe ali ndi vuto laimpso ayenera kusamala posankha mlingo.
Kuchulukitsa kwa Diagninid
Ndi bongo, amuna ndi akazi amakhala ndi hypoglycemia. Pankhaniyi, zizindikiro zotsatirazi zikuwoneka:
- kulakalaka;
- migraine
- mantha
- Kuda nkhawa
- thukuta lozizira;
- nseru
- tachycardia;
- chisokonezo cha chikumbumtima;
- chikomokere.
Ngati vutolo likukhutira, tengani chakudya chamafuta. Woopsa milandu, 50% shuga yankho limayendetsedwa kudzera m'mitsempha.
Kuchita ndi mankhwala ena
Mankhwalawa amalumikizana ndi mankhwala ena motere:
- mphamvu ya kutenga imatheka ndikutenga zoletsa za ATP, ma beta-blockers, anticoagulants, NSAIDs, Probenecid, mowa, anabolic mankhwala, salicylates, Mao inhibitors, sulfonamides;
- calcium blockers blockers, diuretics, corticosteroids, mahomoni a chithokomiro, sympathomimetics, isoniazid, phenothiazines, estrogens ndi phenytoin amatha kufooketsa izi.
Kugwiritsa ntchito kwa gemfibrozil ndikutsutsana.
Mutha kuphatikiza chithandizo ndi thiazolidatediones ndi Metformin. Kugwiritsa ntchito kwa gemfibrozil ndikutsutsana.
Kuyenderana ndi mowa
Amapatsirana kumwa zakumwa zoledzeretsa pamankhwala.
Analogi
Odwala a shuga a Type 2 angasankhe wothandizira wina wa hypoglycemic. Mankhwala otsatirawa ndi ofanana:
- Glidiab;
- Amaryl;
- Attokana;
- Glucophage;
- Diabetesalong;
- Novonorm.
Musanalowe ndi izi ndi analogue, muyenera kupita kwa dokotala. Adzakulemberani mulingo woyenera, poganizira momwe wodwalayo alili ndi zina zake. Mankhwala omwe amaphatikizidwa kwa odwala ena amatha kuyambitsa zovuta.
Musanalowe ndi izi ndi analogue, muyenera kupita kwa dokotala.
Kupita kwina mankhwala
Mankhwala omwe mumalandira amamasulidwa.
Kodi ndingagule popanda kulandira mankhwala?
Mutha kungogula ndi mankhwala kuchokera kwa dokotala.
Mtengo wa Diaglinide
Mtengo wapakati ndi ma ruble 300.
Zosungidwa zamankhwala
Sungani mankhwalawo mu phukusi. Onetsetsani kuti kutentha kumafika mpaka + 25 ° C.
Tsiku lotha ntchito
Moyo wa alumali ndi zaka 2.
Wopanga
Chomera ndi mankhwala Akrikhin, OJSC (Russia).
Madokotala amafufuza
Egor Konstantinovich, katswiri wazamankhwala, Moscow
Chidachi chimagwiritsidwa ntchito pa matenda a shuga a 2. Pakangotha mphindi 30 mutamwa mapiritsi, pali kuchepa kwa shuga m'magazi. Zotsatira zake zimakhala kwa nthawi yayitali. Mankhwala amaletsa kukula kwa hyperglycemia pakati pa chakudya.
Marina Stanislavovna, endocrinologist, Zelenograd
Kuphatikiza apo, mutha kumwa Metformin ndi mankhwala ena a hyperglycemia. Muyenera kuyamba kumwa mankhwalawa ndi mlingo wochepa ndikuyang'anira shuga yanu yamagazi nthawi zonse. Mankhwala abwino, koma popanda mankhwala a dokotala, amatha kuvulaza thupi.
Ndemanga Zahudwala
Anna, wazaka 36, Tufall
Mankhwala otsegula pakamwa hypoglycemic adalembedwa ndi dokotala kuwonjezera pa mankhwala othandizira. Mkhalidwe waumoyo unasintha pakadutsa mphindi 30 mpaka 40 atatha kukhazikitsa. Ndinayamba kupita kuchimbudzi nthawi zambiri ndikungokhala ndi ludzu. Ndili wokondwa ndi kugula.
Eugene, wazaka 45, Tver
Mankhwala okwera mtengo amathandiza kuti magazi asagwere kwambiri. Ngati atengedwa mogwirizana ndi malangizo sayambitsa zovuta.
Ndemanga yakuchepetsa thupi zokhudza Diaglinide
Julia, wazaka 28, Smolensk
Anamwa mankhwalawa kwa milungu ingapo, koma anakana kumwa chifukwa cha zovuta zina. Zinali zotheka kutulutsa kagayidwe, kuti muchotse 2-3 kg. Ndiwothandiza kwambiri kuchita masewera olimbitsa thupi komanso kutsatira zakudya.
