Neurorubin ili ndi mavitamini a B. Chifukwa cha kapangidwe kameneka, njira zabwino pamachitidwe angapo amachitidwe amadziwika. Pa mankhwala ndi mankhwalawa, kagayidwe kachakudya kamabwekanso. Amaperekedwa m'njira zosiyanasiyana: cholimba, chamadzimadzi. Ndi zovuta kwambiri ma pathologies, jakisoni amapangidwa. Mankhwalawa ali ndi contraindication ochepa, chifukwa cha kusowa kwa zinthu zopanda pake zomwe zimapangidwa. Komabe, pamakhala zovuta zingapo zoyipa. Ichi ndichifukwa chosalolera mavitamini ena omwe amatengedwa mu Mlingo waukulu.
Dzinalo Losayenerana
Pyridoxine + cyanocobalamin + thiamine.
ATX
A11DB.
Chifukwa cha zomwe zili ndi mavitamini a B, mankhwalawa Neurorubin amabwezeretsa kagayidwe.
Kutulutsa mafomu ndi kapangidwe kake
Mankhwala amaperekedwa m'mitundu iwiri: mapiritsi ndi jakisoni. M'magawo onse awiriwa, kuphatikiza chimodzi mwazinthu zazikulu kumagwiritsidwa ntchito, koma Mlingo wawo ndi wosiyana. Zinthu zomwe zimagwira ntchito: thiamine, pyridoxine hydrochloride, cyanocobalamin.
Mapiritsi
Mankhwala okhazikika mawonekedwe amaperekedwa m'mapaketi a 20 ma PC. (2 matuza a ma PC 10). Kuchuluka kwa zosakaniza piritsi limodzi:
- thiamine mononitrate - 200 mg;
- pyridoxine hydrochloride - 50 mg;
- cyanocobalamin - 1 mg.
Kuphatikiza apo, malembawa amaphatikizapo zinthu zomwe sizikuwonetsa ntchito:
- mapadi ophatikizika;
- hypromellose;
- wowuma pregelatinized;
- mannitol;
- ma cellcose a microcrystalline;
- magnesium wakuba;
- colloidal silicon dioxide.
Zinthu zogwira zomwe zimagwiritsa ntchito mankhwalawa: thiamine, pyridoxine hydrochloride, cyanocobalamin.
Njira Zothetsera
Mankhwala amaperekedwa mu ma ampoules a 3 ml iliyonse. Mlingo wa zomwe zimagwiritsidwa ntchito zimasiyana ndi kuchuluka kwa zinthu zazikulu pakapangidwe kamapiritsi. Mbale 1 ili ndi:
- thiamine hydrochloride - 100 mg;
- pyridoxine hydrochloride - 100 mg;
- cyanocobalamin - 1 mg.
Kuphatikiza apo, mankhwalawa amaphatikizapo madzi a jakisoni, potaziyamu cyanide, mowa wa benzyl. Phukusili lili ndi ma ampoules asanu.
Zotsatira za pharmacological
Kuphatikizikako kumaphatikizapo mavitamini ambiri: thiamine (B1), pyridoxine (B6), cyanocobalamin (B12). Chitsogozo chachikulu chogwiritsira ntchito ndi kuphatikiza kwa kagayidwe kachakudya, kamene kamayambitsa kuchotsedwa kwa mawonekedwe owoneka kuchokera ku ziwalo zosiyanasiyana komanso chamkati mwamanjenje. Zonse zomwe zimagwira ntchito pakupanga zimachita mosiyana, zimathandizira zotsatira za wina ndi mnzake.
Mwachitsanzo, vitamini B1 kapena thiamine ndi coenzyme ya pentose phosphate njira (transketolase). Komanso imagwira ntchito - imatenga nawo mphamvu zama metabolism. Zidziwikanso kuti vitamini iyi ndi gawo la nthambi ya alpha-keto acid dehydrogenase yomwe imapangidwa ndi catabolism ya leucine, isoleucine ndi valine.
Kuphatikiza apo, vitamini B1 ndi gawo la thiamine triphosphate. Pulogalamuyi imathandizira kufalitsa zikhumbo za mitsempha, mapangidwe a chizindikiro cha ma cell. Pali umboni kuti thiamine triphosphate imakhudzanso kayendedwe ka njira za ion. Chifukwa cha izi, kukula kwa mitsempha kumadziwika, kulimba kwa mawonekedwe ena mu milandu yakuphwanya kwamtunduwu kumatsika. Vitamini uyu amatchedwa antineuritic. Amapezeka muzinthu zotsatirazi: nyemba, nyama, buledi wa bulauni, chimanga, yisiti.
Vitamini B6 imawonetsa ntchito yolimbikitsa, imathandizira kuthamanga kwa metabolism. Ndi coenzyme ya mapuloteni omwe amagwiritsidwa ntchito pokonza ma amino acid. Kuphatikiza apo, vitamini B6 imathandizira kuti chakudya chikhale bwino. Pyridoxine amagwira ntchito popanga maselo amwazi, hemoglobin. Ntchito ina ndikupereka minofu yokhala ndi glucose.
Pyridoxine akusowa: amatha kuthandizira pakukula kwa zinthu zingapo zam'magazi, pakati pa zomwe coronary artery atherosulinosis. Mankhwala othandizira antibiotic, kumwa anti-TB mankhwala osokoneza bongo, kusuta fodya, komanso kuletsa pakamwa kumathandiza kuchepetsa kuchuluka kwa Vitamini B6. Chifukwa chake, ndikofunikira kuwonjezera kupezeka kwa thupi ndi pyridoxine mothandizidwa ndi zinthuzi. Vitaminiyi imapezeka m'chiwindi, nyemba, yisiti, impso, nyama, mbewu monga chimanga. Pazovomerezeka, pyridoxine imapangidwa ndi microflora yamatumbo.
Vitamini B12 imakhudzidwa ndi metabolism ya mapuloteni, chakudya, lipids. Mothandizidwa ndi cyanocobalamin, kayendedwe ka magazi kamabwezeretsedwa, chifukwa kapangidwe ka magazi kamachita bwino. Vitamini amaikidwa ngati antianemic, metabolic. Mothandizidwa ndi iye, kusinthika kwa minofu kumathandizira, ntchito ya chiwindi ndi kwamanjenje imasinthidwa.
Mphamvu zamagazi zimapangidwa modabwitsa (kuthekera kwa kusokonekera kumabwezeretseka). Pakusintha (njira imachitika m'chiwindi), cobamide imamasulidwa, yomwe ndi gawo la michere yambiri. Kuphatikizidwa kwa mavitaminiwa kumathandiza kuchepetsa ululu m'matenda osiyanasiyana amanjenje.
Pharmacokinetics
Mafuta amapezeka m'matumbo. Ikafika m'chiwindi, vitamini B1 imalowetsedwa ndi chiwalochi, koma pang'ono, gawo lotsalazo limasinthidwa ndikupanga metabolites. Impso ndi matumbo ndizo zimapangitsa kuti zithetsedwe. Pyridoxine imasinthidwanso ndikuchita chiwindi. Kukula kwakukulu, vitamini B6 amadziunjikira m'chiwindi, minofu, ndi ziwalo zamanjenje. Zimadziwika kuti amamangirira mapuloteni a plasma. Pyridoxine amamuchotsa impso.
Vitamini B12 pambuyo mayamwidwe kwakukulu kumadziunjikira m'chiwindi. Chifukwa cha kagayidwe, gawo limodzi limamasulidwa. Cyanocobalamin ndi metabolite ake amuchotsa ndikugwira impso, limodzi ndi bile.
Zizindikiro zogwiritsidwa ntchito
Ndikofunika kugwiritsa ntchito chida chomwe mukufunsachi, poganizira momwe mumasulidwa. Mapiritsi ndi yankho zimagwiritsidwa ntchito mosiyanasiyana. Koma pali mitundu yambiri ya momwe mungakhalire zovomerezeka kupereka mitundu yonse ya Neurorubin:
- matenda ashuga polyneuropathy;
- neuralgia ya etiologies osiyanasiyana;
- neuritis ndi polyneuritis.
Njira yothetsera vutoli imagwiritsidwanso ntchito pa hypovitaminosis, pamene vuto la mavitamini a B ladziwika, komanso chithandizo cha beriberi. Komanso, mawonekedwe amadzimadzi a mankhwalawa angagwiritsidwe ntchito ndi monotherapy.
Mapiritsi amalembera zakumwa zamtundu osiyanasiyana, kuphatikizapo zakumwa zoledzeretsa. Komanso, mtundu uwu wamankhwala ungagwiritsidwe ntchito kokha ngati gawo la zovuta mankhwala.
Contraindication
Pali zoletsa zochepa pamankhwala.
- Hypersensitivity ku gawo lililonse la Neurorubin;
- diathesis wa thupi lawo siligwirizana.
Ndi chisamaliro
Odwala omwe ali ndi psoriasis ayenera kuwunika momwe mawonekedwe amtundu wakunja aliri, chifukwa ndi matenda, kutenga mankhwalawo chifukwa chofunsidwa kumatha kuyambitsa kuchuluka kwa mawonekedwe owonetsa. Zofanana ndi zina nthawi zina zimachitika ndi ziphuphu.
Momwe mungatengere neurorubin
Malangizo a mankhwalawa amadzimadzi komanso amitundu yosiyanasiyana ndi osiyana. Chifukwa chake, ngati adotolo adalimbikitsa kumwa mapiritsi, tsiku lililonse mapiritsi a 1-2 amawonedwa kuti ndi okwanira. Sayenera kutafuna. Ndikulimbikitsidwa kumeza mapiritsi ndi madzi. Mankhwala amatengedwa motere tsiku lililonse. Kutalika kwa chithandizo kumagwirizana ndi dokotala aliyense payekha, zomwe zimakhudzidwa ndi mkhalidwe wa wodwalayo komanso kupezeka kwa matenda ena. Komabe, nthawi zambiri, njira yochizira imakhala mwezi umodzi.
Malangizo ogwiritsira ntchito yankho la makolo
- Mlingo wa tsiku lililonse wa matenda amawonekera ndi 3 ml (1 ampoule), mankhwalawa angagwiritsidwe ntchito tsiku lililonse, koma kamodzi pakapita masiku awiri;
- pafupipafupi kugwiritsa ntchito Neurorubin amachepetsa pambuyo kuchepa kwa mphamvu ya zizindikiro za pathological mkhalidwewo, motere ndikuloledwa kupereka jakisoni mopitilira 1-2 pa tsiku (mlingo womwewo - 3 ml patsiku).
Ndi matenda ashuga
Mankhwalawa amatha kugwiritsidwa ntchito pochiza odwala omwe ali mgululi. Mlingo umatsimikiziridwa payekhapayekha poganizira kuchuluka kwa kukula kwa matenda amisempha, chithunzi cha matenda ndi kupezeka kwa zovuta zina.
Zotsatira zoyipa
Choyipa chachikulu cha Neurorubin ndizovuta zambiri zoyipa zomwe zimachitika panthawi yamankhwala. Nthawi zambiri, mankhwalawa amalekeredwa bwino. Zotsatira zoyipa zimachitika pamene thupi lili ndi hypersensitive ku chinthu chilichonse, kupezeka kwa matenda ena, kapena ngati pakulakwira mlingo. Kudzichiritsa wekha kungayambitsenso mavuto ena.
Matumbo
Kuthetsa mseru, kusanza, magazi m'mimba. Ntchito ya plasma glutamine oxaloacetin transaminase imawonjezeka.
Pakati mantha dongosolo
Nkhawa, kusakwiya, kupweteka mutu, kuuma.
Kuchokera ku kupuma
Cyanosis, edema ya m'mapapo.
Pa khungu
Ziphuphu, kukulira khungu ndi ziphuphu.
Kuchokera pamtima
Tachycardia, kukula kwakanthawi kochepa kagwiridwe ka ntchito yamtima wamunthu ndi chiopsezo cha imfa.
Dongosolo la Endocrine
Njira ya kupukusa kwa prolactin imalepheretseka.
Zotsatira zoyipa za mankhwalawa, kufalikira kwakanthawi kwa ntchito ya mtima kumadziwika.
Matupi omaliza
Urticaria, kuyabwa, zidzolo, angioedema, anaphylactic.
Zokhudza mphamvu pakuwongolera njira
Popeza chida chomwe chikufunsidwachi chimakhudza kugwira ntchito kwa mtima wama mtima (kumapangitsa kuti tachycardia, kugwa), osavomerezeka kuyendetsa magalimoto panthawi ya chithandizo.
Malangizo apadera
Chithandizo cha odwala omwe ali ndi vuto la mtima ayenera kuchitidwa moyang'aniridwa ndi dokotala.
Ngati sensor neuropathy imayamba pakumwa mankhwalawa ndi Neurorubin, zotsatira zoyipa zimatha pambuyo posiya izi.
Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere
Zosagwiritsidwa ntchito.
Kulembera Neurorubin kwa Ana
Ndi chololedwa kugwiritsa ntchito mankhwalawa pongofunsira odwala omwe ali ndi zaka zopitilira 18.
Gwiritsani ntchito mu ukalamba
Mankhwala angagwiritsidwe ntchito. Komabe, amawerengedwa kwa odwala popanda kupatuka mu ntchito ya mtima. Pa nthawi yoyamba kuvomerezedwa, muyenera kuyang'anira momwe thupi liliri. Ngati zizindikiro zoyipa zikuchitika, mankhwalawo amachotsedwa.
The ntchito aimpso kuwonongeka
Popeza kuti zigawo zikuluzikulu za mankhwalawa zimapukusidwa ndi gawo la gululi, kusamala kuyenera kuchitika pakumwa.
Gwiritsani ntchito ntchito yolakwika ya chiwindi
Chida choganiziridwa chitha kugwiritsidwa ntchito ndi odwala omwe ali ndi zoterezi, komabe, ndikofunikira kuyang'anitsitsa kusintha kwa thupi.
Pakachitika zovuta, mankhwalawa amayenera kusokonezedwa.
Bongo
Zotsatira zoyipa zimachitika ngati milingo yayikulu ya mankhwalawa (500 mg patsiku) ikulowetsedwa m'thupi kwa nthawi yayitali (kuposa miyezi isanu ndi inayi). Pankhaniyi, chiwopsezo cha kukulitsa minyewa ya m'maganizo chikuwonjezeka, chomwe chimawonetsedwa ndi kupweteka miyendo, kuchepa kwa mphamvu, kumva kugunda, kumva mphamvu. Izi ndi zotsatira za kugonjetsedwa kwa mitsempha yambiri. Mawonekedwe oyipa amadzatha atasiya mankhwala.
Kuchita ndi mankhwala ena
Kuchita bwino kwa mankhwala a antiparkinsonia kumachepetsedwa. Kuwonjezeka kwa mulingo wa poizoni wa isoniazid kumawonetsedwa.
Zinthu zotsatirazi zimatsutsana: Theosemicarbazone ndi 5-fluorouracil. Kukonzekera kwa Antacid kumachepetsa kuyamwa kwa thiamine.
Njira ya Neurorubin siyingasakanikirane ndi njira zina, chifukwa kuphatikiza kwake ndi mitundu ina ya mankhwala sikunaphunzire kwathunthu.
Kuyenderana ndi mowa
Sitikulimbikitsidwa kumwa mankhwalawa komanso nthawi yomweyo kumwa zakumwa zoledzeretsa. Izi ndichifukwa choti zakumwa zakumwa zimapangitsa kuti mavitamini B azitha kuchepa ndipo zotuluka zawo m'thupi zimathamangitsidwa, zomwe zimapangitsa kuti pakhale kusowa kwa michere.
Analogi
M'malo mogwira mtima:
- Vitaxone;
- Nerviplex;
- Milgamma.
Miyezo ya holide ya Neurorubin kuchokera ku mankhwala
Mankhwala mu mawonekedwe a yankho ndi mankhwala. Dokotala sayenera kugula mapiritsi.
Kodi ndingagule popanda kulandira mankhwala?
Inde, koma mwa mawonekedwe okhazikika.
Mtengo wa neurorubin
Mtengo wapakati ku Russia ndi ma ruble 1000. Mtengo wa mankhwalawa ku Ukraine umasiyana pakati pa ma ruble a 230-550, omwe malinga ndi ndalama yadziko ndi 100-237 UAH.
Zosungidwa zamankhwala
Kutentha kwakanthawi kanyumba sikokwanira kuposa + 25 ° ะก. Mankhwalawa ayenera kusungidwa m'malo owuma. Zinthu zoterezi ndizoyenera mapiritsi.
Njira yothetsera vutoli izisungidwa pa kutentha kwa + 2 ... + 8 ° C.
Tsiku lotha ntchito
Piritsi la mankhwalawa lingagwiritsidwe ntchito zaka 4. Njira yothetsera vutoli itha kugwiritsidwa ntchito zaka zitatu kuyambira tsiku lomwe watulutsa.
Wopanga Neurorubin
Wepha GmbH, Germany.
Ndemanga za Neurorubin
Galina, wazaka 29, Perm
Dokotala anachenjeza kuti ndi matenda amphumo am'mimba amatha kuchitika. Koma Zizindikiro zosasangalatsa mwa ine sizinawonekere nthawi yomweyo (ndili ndi gastritis), koma pafupi kwambiri ndi maphunzirowa (sabata lachivomerezo). Zotsatira zamankhwala ndizabwino: kupweteka kumachepa, mkhalidwe wamaganizidwe wapambana.
Veronika, wazaka 37, Yaroslavl
Gwiritsani ntchito mankhwalawa chifukwa chakusokoneza kwamanjenje. Nthawi yoyamba ankalandira jakisoni. Pambuyo pake, Zizindikiro zake sizinatchulidwe, motero ndinasintha mapiritsi. Zotsatira zoyipa sizinachitike, mankhwalawa amalekeredwa bwino. Sindinganene kuti mapiritsiwo ndi othandiza bwanji, chifukwa ndinawamwa pamodzi ndi mankhwala ena.
