Dapril: Malangizo ntchito

Dapril ndi mankhwala othandizira komanso otchipa a antihypertensive. Amasintha magazi kupita ku ischemic myocardium, amachepetsa kuthamanga kwa magazi, OPSS ndikutsitsa.

Dzinalo Losayenerana

INN ya mankhwalawa ndi lisinopril.

ATX

Khodi ya ATX ndi C09AA03.

Wothandizira antihypertensive amapangidwa ngati mapiritsi a pinki, omwe amayikidwa mu mizere 10 ma PC.

Kutulutsa mafomu ndi kapangidwe kake

Wothandizira antihypertensive amapangidwa ngati mapiritsi a pinki, omwe amayikidwa mu mizere 10 ma PC. Mu paketi imodzi ya 2 kapena 3 mizere. Piritsi 1 imakhala ndi 5, 10 kapena 20 mg ya lisinopril, yomwe ndi gawo lalikulu la mankhwalawa. Zothandiza:

• wowuma wa gelatinized;
• calcium hydrogen phosphate;
• utoto E172;
• mannitol;
• magnesium wakuba.

Zotsatira za pharmacological

Chidacho chili ndi ntchito ya antihypertensive ndipo ndi ya gulu la zoletsa zoletsa za ACE. Mfundo ya zochita zake za pharmacotherapeutic ikufotokozedwa ndi kukakamiza kwa ntchito ya ACE, kutembenuka kwa angiotensin 1 kupita ku angiotensin 2. Kuchepa kwa plasma ya kumapeto kumayambitsa kuwonjezeka kwa ntchito za renin komanso kuchepa kwa kupanga kwa aldosterone.

Mankhwala amachepetsa pambuyo- ndi preload, kuthamanga kwa magazi ndi zotumphukira mtima kukana.

Mankhwalawa amayamba kugwira ntchito mkati mwa mphindi 120 mutatha kugwiritsa ntchito. Zochita kwambiri zimalembedwa pambuyo pa maola 4-6 ndipo zimatha mpaka tsiku limodzi.

Pharmacokinetics

The bioavailability wa lysinoril ukufika 25-50%. Mulingo wake wapamwamba kwambiri wa plasma umapezeka mu maola 6-7. Chakudya sichikhudza mayamwidwe a antihypertensive mankhwala. Sipangaphatikizidwe ndi mapuloteni a plasma; sikuti amakhala ndi thupi lambiri. Amachotseredwa ndi impso zoyambirira. Kuchotsa theka moyo ndi maola 12.

Chakudya sichikhudza mayamwidwe a antihypertensive mankhwala.

Zizindikiro zogwiritsidwa ntchito

Mankhwala osokoneza bongo a antihypertgency amatchulidwa motere:

• mawonekedwe osalephera a minofu ya mtima kulephera (mukamagwiritsa ntchito kukonzekera kwa digitalis ndi / kapena okodzetsa, ngati gawo la chithandizo chovuta);
• matenda oopsa a arterial (amaloledwa kugwiritsa ntchito mankhwalawa mu monotherapy kapena kuphatikiza ndi antihypertensive mankhwala).

Contraindication

Kuletsa kwa mankhwala ndi izi:

• mawonekedwe oyamba a hyperaldosteronism;
• zaka zosakwana 18;
• mbiri ya edema ya Quincke;
• kusalolera munthu lisinopril ndi yachiwiri zosakaniza mankhwala;
• 2 ndi 3 trimester ya gestation;
• kuyamwitsa;
• Hyperkalemia
• azotemia;
• kwambiri / pachimake aimpso kuwonongeka;
• kuchira pambuyo kumuika impso;
• bilatal mawonekedwe a stenosis a mitsempha ya impso.

Mankhwalawa sayenera kumwa kwa anthu ochepera zaka 18.

Contraindication pakugwiritsira ntchito mankhwalawa ndi 2nd ndi 3 trimester ya mimba.

Ndikofunika kupewa kumwa mankhwalawa panthawi yochepa mkaka.

Kuchepetsa kwambiri / kupweteka kwambiri kwaimpso kumatinso kuphwanya kugwiritsa ntchito mankhwalawa.

Mosamala, muyenera kugwiritsa ntchito mankhwalawa kwa anthu omwe ali ndi vuto la mtima ndi mitsempha yamagazi.

Mosamala, mankhwalawa amayenera kugwiritsidwa ntchito motsutsana ndi maziko a kulowerera kwamatenda am'matumbo, chizolowezi chowonjezereka cha matenda a mtima, komanso mavuto ena a mtima.

Momwe mungatenge Dapril

Mlingo wothandizira ochepa matenda oopsa amaperekedwa palokha, chifukwa cha kuthamanga kwa magazi.

Mlingo woyambirira ndi 10 mg / tsiku, mlingo wothandizira ukufika mpaka 20 mg / tsiku. Mlingo wapamwamba tsiku lililonse ndi 80 mg.

A aakulu mawonekedwe a mtima kulephera amayamba kuthandizidwa ndi Mlingo wa 2,5 mg / tsiku. Ndiye kuchuluka kwa mankhwalawa kumasankhidwa malinga ndi zochita za pharmacological zomwe zimapezeka ndipo ndi 5-20 mg patsiku.

Ndi matenda ashuga

Anthu omwe ali ndi matenda ashuga, akamamwa mankhwala othandizira, ayenera kuwunika kuchuluka kwa shuga m'magazi. Mlingo wa odwala a gululi amasankhidwa payekha.

Anthu omwe ali ndi matenda ashuga, akamamwa mankhwala othandizira, ayenera kuwunika kuchuluka kwa shuga m'magazi.

Zotsatira zoyipa za Dapril

Matumbo

Potengera zakumwambazo, wodwalayo amatha kusanza, kusasangalala ndi epigastrium, pakamwa kowuma, ndi m'mimba.

Hematopoietic ziwalo

Mankhwalawa nthawi zina amachititsa kuchepa kwa maselo ofiira am'magazi ndi hemoglobin, agranulocytosis ndi neutropenia.

Pakati mantha dongosolo

Kuchokera kumbali ya dongosolo lamkati lamanjenje, chizungulire, kumva kufooka, kupweteka mutu, kuda nkhawa komanso kusinthasintha mwadzidzidzi kumachitika.

Kuchokera ku kupuma

Pogwiritsa ntchito mankhwalawa, chifuwa chowuma nthawi zina chimawonedwa.

Mukamamwa mankhwalawa, mseru komanso kusanza kumachitika.

Mankhwala amatha kuyambitsa matenda otsegula m'mimba.

Nthawi zina, mankhwalawa angayambitse chizungulire.

Chimodzi mwazotsatira zoyipa za mankhwalawa ndi kusinthasintha kwa machitidwe.

Nthawi zina, kutenga Dapril kumatsatana ndi chifuwa chowuma.

Kutengera komwe kumamwa mankhwalawa, pakamwa youma kumatha kuchitika.

Dapril ikhoza kuyambitsa kufooka.

Kuchokera pamtima

Mankhwalawa amachititsa kuti khungu lizigwirana ndi khungu, khungu la orthostatic hypotension ndi tachycardia.

Matupi omaliza

Odwala ndi hypersensitivity a zigawo zikuluzikulu za mankhwalawa, kuyabwa ndi totupa pakhungu kumatha kuchitika. Nthawi zina, angioedema amakula.

Zokhudza mphamvu pakuwongolera njira

Popeza kuti mankhwala a antihypertensive angayambitse chizungulire komanso kusazindikira bwino, tikulimbikitsidwa kupewa kuyendetsa galimoto ndi zina mwa njira poyambira kugwiritsa ntchito kwake.

Ngakhale mukutenga Dapril, ndibwino kukana kuyendetsa galimoto.

Malangizo apadera

Tiyenera kukumbukira kuti kupsinjika kumatha kuchepa kwambiri ndi kuchepa kwamadzi mu thupi ndikumwa mankhwala okodzetsa, ndi kuchepa kwa mchere m'zakudya ndikukhazikitsa njira za dialysis. Odwala otere ayenera kuyamba kulandira chithandizo motsogozedwa ndi dokotala. Mlingo amasankhidwa mwamseri.

Gwiritsani ntchito mu ukalamba

Kusankha kwapadera sikofunikira.

Kupatsa ana

Mankhwala a antihypertensive muopadokotala sagwiritsidwa ntchito.

Kuyenderana ndi mowa

Akatswiri salimbikitsa kumwa mowa pogwiritsa ntchito mankhwala a antihypertensive.

Akatswiri salimbikitsa kumwa mowa pogwiritsa ntchito mankhwala a antihypertensive.

The ntchito aimpso kuwonongeka

Mlingo wamtunduwu umasankhidwa malinga ndi chilolezo cha creatinine.

Gwiritsani ntchito ntchito yolakwika ya chiwindi

Mankhwala a antihypertensive amaperekedwa mosamala pazilonda zofatsa komanso zolimbitsa thupi. Woopsa milandu, ntchito contraindised.

Mankhwala osokoneza bongo a Dapril

Nthawi zambiri amawonetsedwa ndi ochepa ochepa hypotension, aimpso ntchito ndi electrolyte bwino. Chithandizo cha mankhwalawa chimakhudzana ndi kukonzekera kwa njira ya saline ndi hemodialysis.

Kuchita ndi mankhwala ena

Kuphatikiza kwa lisinopril ndi potaziyamu wotsekemera mtundu okodzetsa, kulocha mchere ndi kukonzekera kwa potaziyamu, chiopsezo cha hyperkalemia chikuwonjezeka.

Mukaphatikiza mankhwala ndi antidepressants, kuchepa kwakukulu kwa magazi kumawonedwa.

Mukaphatikiza mankhwala ndi antidepressants, kuchepa kwakukulu kwa magazi kumawonedwa.

Ntchito ya antihypertensive ya lisinopril imachepetsedwa limodzi ndi mankhwala omwe si a antiidal.

Ethanol kumawonjezera hypotensive zotsatira za lisinopril.

Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere

Kumwa mankhwalawo ndizoletsedwa mu 2nd ndi 3 trimesters, chifukwa lisinopril amatha kudutsa placenta.

Ngati mankhwalawa adayikidwa panthawi ya mkaka wa m'mawere, muyenera kupewa kuyamwitsa.

Analogi

Omwe amathandizira pakumwa mankhwala a antihypertensive ndi awa:

• Rileys-Sanovel;
• Liteni;
• Sinopril;
• Zovomerezeka;
• Lister;
• Lysoril;
• Lisinopril granate;
• Lisinopril dihydrate;
• Lisinotone;
• Lysacard;
• Zonixem;
• Irume;
• Diroton;
• Diropress.

Kupita kwina mankhwala

Mankhwala a antihypertensive amapezeka pamankhwala.

Mtengo

Mtengo wapakati wa mankhwalawa m'masitolo a Russian Federation ndi ma ruble 150. a pack No. 20.

Zosungidwa zamankhwala

Mankhwalawa ayenera kutetezedwa kwa ana, kuwala kwa dzuwa, chinyezi komanso kutentha kwambiri.

Tsiku lotha ntchito

Zaka 4

Wopanga

Kampani "Medochemie Ltd" (Kupro).

Mankhwala a antihypertensive amapezeka pamankhwala.

Ndemanga

Valeria Brodskaya, wazaka 48, Barnaul

Chida chothandiza kukhazikika magazi. Ndakhala ndikugwiritsa ntchito kwa nthawi yayitali (pafupifupi zaka 5). Munthawi imeneyi, sindinawonepo zoyipa zilizonse, zotengedwa molingana ndi malangizo azachipatala, osapitilira muyeso komanso osaphonya mlingo. Kupanikizika kumakhala kotheka m'maola 1-1,5. Ndiotsika mtengo. Tsopano ndikupangira izi kwa anzanga onse.

Petr Filimonov, wazaka 52, mzinda wa Mines

Mankhwalawa adalimbikitsidwa ndi wokondedwa wanga. Ndimamwa ndikamayamba kukakamizidwa kuti "wopanda pake". Zimathandiza mwachangu. Mankhwala amatenga nthawi yayitali. Kwa sabata limodzi lovomerezeka, mkhalidwe wanga unayenda bwino, mtima wanga unadzuka. Magulu oyang'ana pamaso panga anazimiririka ndikusintha kwakanthawi kwamayendedwe.

Denis Karaulov, wazaka 41, Cheboksary

Mankhwala okhawo olimbitsa bata omwe thupi langa linatenga modekha. Ndinakhuta nazo. Mtengo wotsika mtengo, chitani zinthu mwachangu komanso motalika.

Varvara Matvienko, wazaka 44, Smolensk

Ndakhala ndikugwiritsa ntchito mankhwala a antihypertgency kwa zaka zoposa ziwiri. Ndakhutira kwathunthu ndi momwe zimakhalira, kukakamiza kumayendedwe ake kwakanthawi kochepa, sikudumpha. Piritsi limodzi patsiku limakhala bwino tsiku lonse. Nthawi yomweyo ndimavomereza zothandizira kudya. Panalibe mavuto.