Zotsatira za mankhwala a Humalog Remix mu shuga

Humalog Mix ndi gulu la othandizira a hypoglycemic. Amaperekedwa mu mawonekedwe amadzimadzi, amapatsidwa mitundu ya matenda a shuga omwe amadalira insulin. Mtengo wa mankhwalawo ndi wapamwamba pang'ono. Amagwiritsidwa ntchito kuteteza matenda a shuga. Mankhwala amadziwika ndi dera laling'ono logwiritsira ntchito. Zopindulitsa zimaphatikizapo zoletsa zingapo pazogwiritsa ntchito.

Dzinalo Losayenerana

Lyspro insulin ndi biphasic.

Mankhwala Humalog Remix amapezeka mu mtundu wa yankho lomwe limapangidwa pakayendetsedwe ka subcutaneous.

ATX

A10AD04.

Kutulutsa mafomu ndi kapangidwe kake

Mankhwala amaperekedwa mu mawonekedwe a zinthu zamadzimadzi. Njira yothetsera vutoli ndi yopanga subcutaneous makonzedwe. Monga ntchito yogwira, insulin lyspro imagwiritsidwa ntchito. Ili ndi mitundu iwiri yosiyanasiyana, yabwino kwambiri pa liwiro la chiwonetsero cha katundu: insulin solution lyspro (panthawi ya 25 ndi 50%), imapereka chithandizo nthawi yomweyo; Lyspro protamine kuyimitsidwa kwa insulin (75 ndi 70%, motero) - zotulukapo zake zimafalikira kwakanthawi. Kusasinthika kofunikira kwa mankhwala kumaperekedwa ndi zotsatirazi zomwe sizikuwonetsa ntchito ya hypoglycemic:

• metacresol;
• phenol madzi;
• glycerol;
• protamine sulfate;
• sodium hydrogen phosphate heptahydrate;
• zinc oxide qs yopanga ma ayoni a zinc;
• madzi a jakisoni;
• 10% yankho la hydrochloric acid ndi / kapena sodium hydroxide kwa pH ya 7.0-7.8.

Mutha kugula katunduyo phukusi lokhala ndi matuza 1 (ma cartridge 5, 3 ml ya kuyimitsidwa). Makatoni amaikidwa mu cholembera cha syringe cha QuickPen TM. Phukusilo limatha kukhala ndi zinthu zisanu.

Zotsatira za pharmacological

Kuphatikizika kwa mankhwalawa kumaphatikizanso cholowa cha DNA chophatikizira insulin ya anthu. Mfundo zoyendetsera ntchito zimatengera kusintha kwa kapangidwe ka shuga.

Mfundo za mankhwalawa zimatengera kusintha kwa kapangidwe ka shuga.

Kuphatikiza apo, mankhwalawa amadziwika ndi katundu wa anabolic (amathandizira kukulitsa kukula kwa minofu), motero Humalog ikhoza kugwiritsidwa ntchito pamasewera.

Mankhwalawa amawonetseranso anti-catabolic athari. Chifukwa chake, mchikakamizo chake, zoletsa zamkati mwa kuphwanya mapuloteni zimadziwika. Katundu wa anabolic ndi anti-catabolic amalumikizana.

Zotsatira za njirazi ndikuwonjezereka kwa kuchuluka kwa mafuta acid, glycogen, glycerol.

Nthawi yomweyo, kuwonjezeka kwa kuchuluka kwa mapuloteni amodzi amadziwika, komanso kufunikira kwa thupi kwa amino acid kumawonjezeka. Nthawi yomweyo, kuwonongeka kwa mafuta, kupanga matupi a ketone, komanso njira monga gluconeogeneis, glycogenolysis, kumachepetsedwa.

M'malo mwake lyspro ndi ofanana ndi insulin yomwe ili m'thupi la munthu, imasiyanitsidwa ndi kuchuluka kwa kuchitapo kanthu. Komabe, thunthu limakhala ndi choletsa: zomwe zimapezeka sizimatenga nthawi yayitali.

Pharmacokinetics

Mlingo wa mayamwidwe a insulin ndiwokwera. Pambuyo mphindi 15, kusintha kwa mkhalidwe wa wodwalayo kumadziwika. Kuchuluka kwa ntchito ya chinthu sikufika pasanathe maola 2,5.

Mlingo wa mayamwidwe a insulin ndiwokwera. Pambuyo mphindi 15, kusintha kwa mkhalidwe wa wodwalayo kumadziwika.

Zizindikiro zogwiritsidwa ntchito

Chida chomwe chikufunsidwa chimadziwika ndi dera laling'ono logwiritsa ntchito. Amawerengera odwala matenda ashuga mu mawonekedwe odalira insulin.

Contraindication

Mankhwalawa sagwiritsidwa ntchito pothandizira tsankho. Chinsinsi china ndi mkhalidwe wa matenda monga hypoglycemia. Pankhaniyi, kutsika kwamphamvu kwa glucose kumadziwika chifukwa cha insulin lyspro. Izi zingayambitse kuchepa kwakukulu kwa kuchuluka kwake m'magazi.

Mankhwala amagwiritsidwa ntchito mosamala pakulephera kwa chiwindi. Potere, kuyamwa kwa gawo lolimba kumawonjezeka, ndipo zotulukazo zimasungidwa kwakanthawi. Pankhani ya kuwonongeka kwa impso, mankhwalawa amatha kugwiritsidwanso ntchito, koma ndikofunikira kuyang'anira wodwalayo nthawi zonse. Kuphatikiza apo, mosamala, mankhwalawa amafunsidwa milandu ingapo:

• kupsinjika
• kuchuluka kwa zolimbitsa thupi;
• kusintha kwa mtundu wa chakudya, zakudya.

Tiyenera kudziwa kuti kugwiritsa ntchito nthawi yayitali nthawi zambiri kumayambitsa matendawa omwe amayambira hypoglycemia.

Zotsatira zofananazo zimakwaniritsidwa pamaso pa matenda a matenda am'mimba monga matenda a shuga.

Hypoglycemia ndi njira ya m'magulu momwe kugwiritsa ntchito mankhwalawa Humalog Remix kumapangidwira.

Momwe mungatengere Humalog Remix

Mankhwala ndi mankhwala asanadye. Njira yothetsera vutoli iyenera kugwiritsidwa ntchito mphindi 15 musanadye. Izi zatheka chifukwa chakupezeka mwachangu kwa chinthucho. Nthawi zina, mankhwalawa amaperekedwa nthawi yomweyo chakudya chisanachitike, kupuma sikukwaniritsidwa. Lyspro insulin imagwiritsidwa ntchito pokhapokha. Mothandizidwa ndi mtsempha wa magazi amaloledwa. Kuthamanga kwa chochita cha mankhwala kumadalira komwe khungu limakwapulidwa: ntchafu, phewa, matako, m'mimba.

Komanso, ndikofunikira kusinthanitsa tsamba la mankhwala jakisoni. Pafupipafupi pakubwezeretsa mankhwala kudzera mu 1 point sikupitilira 1 nthawi pamwezi. Mankhwala sayenera kulowa mtsempha wamagazi ndi subcutaneous makonzedwe. Kuyimitsidwa kumagwiritsidwa ntchito pokhapokha ngati kutentha kwake kukufanana ndi kutentha kwa chipinda. Malangizo ogwiritsa ntchito cholembera:

• ndikofunikira kukwaniritsa kuyanjana kofananira kwa yankho, komwe ndikulimbikitsidwa kuti mugwedezeke syringe pakati pa manja kangapo, komabe mutembenuzire mosinthana, koma simungathe kuigwedeza, chifukwa thovu limawonekera, zomwe zimapangitsa kuti zikhale zovuta kudziwa mlingo wa mankhwalawo;
• Lyspro insulin ikhoza kugwiritsidwa ntchito ngati itasinthasintha; pamaso pa ma flakes, ngakhale atasakanikirana, kuyimitsidwa sikungagwiritsidwe ntchito;
• 1 syringe yomwe ili ndi 3 ml ya mankhwala kapena 300 IU yogwira ntchito, kamodzi kovomerezeka kulowa kuchokera ku 1 mpaka 60 mayunitsi, ndipo mwayi wa cholembera ndikutha kudziwa mlingo wa mankhwalawa;
• musanalowetse singano pamtundu wakunja wa manja, manja ndi khungu pakamtundu womwe akuti wakupangirayo uyenera kuthandizidwa.

Payokha, malangizo okonza syringe kuti agwiritse ntchito amaperekedwa:

1. Muyenera kukoka kapu kuti muchotse, simuyenera kuzungulira.
2. Konzani singano yatsopano. Kuti muchite izi, chotsani chizindikiro kuchokera kumapeto kwake. Wogwirizira ndi singano amathandizidwa ndi yankho la antiseptic ndikuyimika pa cholembera.
3. Cheke chimapangidwa kuti pakhale insulini, ndipo ndikofunikira kudikirira mpaka nkhani itadutsa.
4. Gawo la zokutira zakunja limakhazikika, ndiye kuti singano imayikidwa ndikuyika batani ndikukanikizidwa, mutayiyika kale momwe mungafunire.
5. Singano imachotsedwa pachikuto chakunja. Nsonga yake imalimbikitsidwa kuti ikhale yotsekedwa ndi kapu, ndipo tsamba la jakisoni la insulin limakutidwa ndi swab ya thonje, pomwe muyenera kupereka kukakamiza pang'ono pakhungu. Kupukuta chivundikiro chakunja m'derali ndizosatheka. Atagwira kwa masekondi angapo, swab ya thonje imachotsedwa.
6. Chovala chodzitchingira chikatha kuyika singano, chimayenera kutsekedwa ndikutayidwa.

Pamaso pa chithandizo chilichonse cha mankhwalawa, singano yatsopano imayikidwa. Kuphatikiza apo, muyenera kuyang'ana nthawi zonse za kumaliza kwa insulin (pa syringe).

Ndi matenda ashuga

Mlingo wa akulu ndi ana umaperekedwa payekhapayekha. Malangizo a mankhwalawa amasankhidwa malinga ndi kuchuluka kwa shuga m'thupi.

M'masewera

Mankhwala omwe amafunsidwa akuwonetsa ofooka a anabolic, anti-catabolic. Komabe, kugwiritsa ntchito insulin pambuyo pakuchita masewera olimbitsa thupi kumathandizira kuti akulepheretsa kusintha kwa amino acid kukhala glucose. Zotsatira zake, mapuloteni sagwiritsidwa ntchito ndi thupi kukwaniritsa zosowa zamphamvu, koma kubwezeretsa minofu minofu. Musanapereke mankhwala, funsani dokotala, monga Kugwiritsa ntchito insulin mosasamala kungakhale pachiwopsezo cha moyo.

Kugwiritsa ntchito mankhwalawa Humalog Remix pambuyo pophunzitsa masewera kumafunika kufunsa dokotala.

Maola angati ndi ovomerezeka

Achire zotsatira zimapitirira kwa maola atatu otsatira. Nthawi zina, insulin imatha mpaka maola 5.

Zotsatira zoyipa

Mankhwalawa, zimachitika kuti mutha kukhala ndi hypoglycemia, makamaka, kukomoka. Zizindikiro zina ndi:

• njala yayikulu;
• chikumbumtima;
• Chizungulire
• kuchuluka kwa thukuta kumachuluka;
• kugunda kwa mtima kwasokonezeka (tachycardia);
• dzanzi la miyendo;
• chikomokere.

Kuphatikiza apo, zotsatira zina zimadziwika:

• ziwengo, zomwe nthawi zambiri zimawonetsedwa ndi zizindikiro zakumaloko: mkwiyo, kufupika kwa khungu, kutupa, komwe kumachitika chifukwa cha kusamveka bwino kwa njira yothetsera antiseptic ndi thupi kapena kuphwanya malamulo oyendetsera mankhwala
• zokhudza thupi lawo siligwirizana amakula pafupipafupi, mwanjira imeneyi Zizindikiro zikuwonetsa kuyimitsidwa kwambiri, edema yambiri, kulephera kupuma, hypotension, kufupika, Hyperhidrosis.

Chizungulire ndichotheka chotsatira chogwiritsira ntchito mankhwalawa Humalog Remix.

Tachycardia ndi zovuta zina zomwe zimakhudzidwa ndi mankhwala a Humalog Mix.

Kulephera kopumira, kufupika ndi zotsatira zochepa zomwe zimachitika panthawi yogwiritsira ntchito Humalog Remix.

Zokhudza mphamvu pakuwongolera njira

Cholinga cholondola, komanso kugwiritsa ntchito mankhwalawa pofunsa, sikuthandizira kuchepa kwa chidwi, sikumabweretsa kuphwanya kwa ntchito zofunika. Chifukwa chake, chitha kugwiritsidwa ntchito pa matenda ashuga. Komabe, muyenera kusamala, chifukwa kugwiritsa ntchito mankhwalawa kwa nthawi yayitali kumayambitsa hypoglycemia.

Malangizo apadera

Cholembera cha syringe chiyenera kusungidwa padera ndi singano. Ngati nsikayo singachotsedwe, mankhwalawo amatha kupukuta kapena kutayikira kwathunthu.

Syringe imasungidwa pansi moyenera. Mukazisunga kunja kwa firiji, mankhwalawo amawonongeka.

Sitikulimbikitsidwa kuti musinthe mtundu, mtundu kapena mitundu ya insulin panthawi ya mankhwala.

Nthawi yomweyo, kusintha kwa kuchuluka kwa komwe kumagwira ntchito ndikuwongolera kwa dokotala nthawi zambiri kumafunikira.

Odwala omwe ali ndi mtundu woyamba wa matenda a shuga, kuphwanya malamulo a insulin, kusowa kwachangu kwa zochiritsira ndizomwe zimayambitsa hyperglycemia, matenda ashuga a ketoacetosis.

Kuchepa kwa impso ndi chiwindi kumathandizira kuchepetsa kufunikira kwa insulini mu shuga.

Mankhwala okhala ndi kuchuluka kwa kuyimitsidwa kwa lyspro okwanira 25% amatha kuperekedwa kwa ana opitirira zaka 12. Pamafunika kuthandiza odwala ochepera zaka izi, insulin imagwiritsidwa ntchito ngati zotsatira zabwino zimapitilira kuvulaza kwakukulu.

Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere

Poganizira kuti kafukufuku wokhudzana ndi insulin pamimba ya mwana wosabadwa kapena wamkazi panthawi yopereka mwana ndikuyamwitsa sichinachitike, mankhwala ayenera kutumizidwa ngati zotsatira zabwino zitha kuvulaza. Mu trimester yoyamba, kufunika kwa insulin nthawi zambiri kumachepera. Mu trimesters 2 ndi 3, Mosiyana, zimawonjezeka.

Mankhwala Humalog Remix amawonetsedwa pa mimba ngati zotsatira zake zabwino zitha kuvulaza.

Kuyenderana ndi mowa

Mukamamwa zakumwa zoledzeretsa, wothandizirayo pamafunso amakhala ndi ntchito zambiri.

Bongo

Ngati mankhwalawa atengedwa kwa nthawi yayitali kapena njira yachipatala itaphwanyidwa (milingo yayikulu ya insulin imayendetsedwa), chiopsezo cha hypoglycemia chikuwonjezeka. Pakuwonetsedwa koyipa komwe tafotokozazi, kusinthaku kwa mankhwalawo kumafunikira, kuwonjezera, kuchuluka kwa shuga kumakhala koyenera mwa kutenga mankhwala okoma (mwachitsanzo, shuga).

Ndi zizindikiro zofooka za hypoglycemia, muyezo wofanana ndi kuchepa kwa zochitika zolimbitsa thupi umagwira.

Mu pathological mkhalidwe wolimba mwamphamvu, mulingo wa shuga umakonzedwa ndi kayendedwe ka glucagon (subcutaneously). Pambuyo pa izi, zakudya zamafuta ochulukirapo zimalimbikitsidwa. Njira zomwezi zimatengedwa kuti ziwonetse kwambiri hypoglycemia, koma mu nkhani iyi, glucagon imathandizidwanso kudzera mu intramuscularly / mtsempha wa magazi.

Kuchita ndi mankhwala ena

Kuchita bwino kwa Humalog Remix kumatha kuchepetsedwa ndikugwiritsidwa ntchito motere:

• glucocorticosteroids;
• njira zakulera pakamwa;
• mahomoni a chithokomiro omwe ali ndi ayodini;
• diuretics a gulu la thiazide;
• beta2-adrenergic agonists;
• othandizira omwe ali ndi phenothiazine zotumphukira;
• Isoniazid;
• nicotinic acid.

Mukamayanjana ndi mankhwala Isoniazid, mphamvu ya Humalog Remix imachepetsedwa.

Mlingo wogwira ntchito umachuluka mothandizidwa ndi mankhwalawa:

• mankhwala a anabolic;
• beta-blockers;
• mankhwala a tetracycline;
• ena othandizira a hypoglycemic;
• antimicrobial mankhwala a sulfanilamide gulu;
• salicylates;
• nthumwi za angiotensin zotembenuza gulu la enzyme inhibitor.

Analogi

M'malo wamba ndi Insulin Lizpro magawo awiri.

Vacation Hum Humgaga Sakanizani kuchokera ku mankhwala

Mankhwala ndi gulu la mankhwala omwe mumalandira.

Kodi ndingagule popanda kulandira mankhwala?

Ayi.

Mtengo wa Humalog Mix

Mtengo wapakati ndi ma ruble 1800.

Humalog Remix imangopezeka ndi mankhwala okha.

Zosungidwa zamankhwala

Kutentha kumatha kusintha pakati pa + 2 ... + 8 ° С. Pambuyo potsegula ma phukusi, syringe imatha kusungidwa m'nyumba ngati kutentha kwa mpweya sikupitirira + 30 ° C.

Tsiku lotha ntchito

Mankhwala osindikizidwa otsekemera sataya katundu wake kwa zaka zitatu kuyambira tsiku lomwe amatulutsa. Pambuyo kutsegulira amatha kugwiritsidwa ntchito mkati mwa masiku 28.

Wopanga Wophatikizira wa Humalog

Lilly France, France.

Ndemanga za Humalog Mix

Veronika, wazaka 38, Nizhny Novgorod

Mankhwalawa amachita mwachangu, ndiye mwayi wake waukulu. Koma sindimakonda momwe zimagwirira ntchito: amasintha glucose ochulukirapo kukhala mafuta, omwe amakhudza kulemera. Ngakhale analogue sinathe kusankhidwa, ndikupitilizabe kugwiritsa ntchito chida ichi.

Anna, wazaka 42, Perm

Mankhwala ndi osavuta kugwiritsa ntchito: mutha kudzipangira nokha, kuwongolera moyo wa alumali wa insulin mu syringe. Ndizomvetsa chisoni kuti zotsatira zake zimatha msanga. Kupanda kutero, mankhwalawa amandiyenerera. Mtengo ndi wokwera pang'ono, koma pazachuma cha gululi ndimaona kuti ndiwo amtengo.