Momwe mungagwiritsire mankhwala osinopril 20?

Lisinopril 20 - njira yothandizira mpumulo wa zizindikiro za matenda oopsa.

Dzinalo Losayenerana

Lisinopril.

Lisinopril 20 - njira yothandizira mpumulo wa zizindikiro za matenda oopsa.

ATX

Khodi ya ATX ndi C09AA03.

Kutulutsa mafomu ndi kapangidwe kake

Mankhwala amapezeka piritsi. Mapiritsiwo ali ndi lisinopril mu mawonekedwe a dihydrate. Zomwe zimagwiritsidwa ntchito zimatha kukhala zosiyanasiyana. Piritsi limodzi lili ndi 5 mg, 10 mg kapena 20 mg ya lisinopril.

Zotsatira za pharmacological

Mphamvu yogwira ya wothandizirayo ndi ya gulu la angiotensin-kutembenuza ma enzyme zoletsa. Mothandizidwa ndi mankhwalawa, zomwe zili ndi angiotensin 2 ndi aldosterone m'magazi zimachepa.

Kupanikizika kwa magazi kumacheperanso chifukwa chobisalira kwambiri pa bradykinin, chinthu chomwe chili ndi mphamvu yodutsa. Vasodilation kumabweretsa kuchepa kwa zotumphukira mtima kukana. Katundu pa minofu ya mtima amachepa, omwe amatha kupopa magazi omwewo ndi ochepa minyewa. Kukula kwa magazi m'mitsempha ya impso kumakulanso.

Mukamamwa pakamwa, kuchuluka kwa kuthamanga kwa magazi kumachepa pambuyo pa ola limodzi. The mulingo woyenera zimatheka mu 6 maola.

Mukamamwa pakamwa, kuchuluka kwa kuthamanga kwa magazi kumachepa pambuyo pa ola limodzi. The mulingo woyenera zimatheka mu 6 maola. Kutalika kwa zochita zimatengera kuchuluka kwa zinthu zomwe zimatengedwa. Ikagwiritsidwa ntchito muyezo waukulu, ntchito zimatha pafupifupi tsiku limodzi.

Lisinopril amakhala ndi chokhazikika cha hypotensive nthawi yonse yogwiritsira ntchito. Kuchepetsa kwakanthawi kwamankhwala kumapangitsa kuti magazi achepe.

Ngakhale kuti lisinopril imalepheretsa ntchito ya angiotensin-kutembenuza enzyme, imakhudza kagayidwe ka angiotensin-aldosterone dongosolo, pogwiritsa ntchito nthawi yayitali, mankhwalawa amathandizanso kukakamiza odwala omwe ali ndi ziwengo zochepa.

Kuphatikiza pa hypotensive zotsatira, mankhwalawa amachepetsa nawonso kuchuluka kwa albumin mu mkodzo. Lisinopril sichikhudzanso kuchuluka kwa shuga m'magazi.

Pharmacokinetics

Mayamwidwe yogwira zigawo zikuluzikulu za wothandizila zimachitika kudzera mucosa wa m'matumbo aang'ono. The bioavailability wa mankhwala zimatengera mawonekedwe a wodwala thupi. Amachokera ku 5 mpaka 50%.

Kuzindikira kwamphamvu kwambiri m'magazi mukamamwa pakatha maola 7. Kubzala sikudalira nthawi yakudya.

Kuzindikira kwamphamvu kwambiri m'magazi mukamamwa pakatha maola 7.

Zomwe zimagwiritsidwa ntchito sizikumanga ma peptides a plasma. Kumangiriza kumachitika kokha ndi angiotensin kutembenuza enzyme. Lisinopril amatha kudutsa BBB pamiyeso yaying'ono.

Gawo logwirika silikusintha ma metabolic. Kuchoka kumachitika momwe zimakhalira kale. Madzi amadzimadzi. Hafu ya moyo ndi maola 12.

Normal aimpso kulenga chilolezo cha 50 ml / min. Gawo lamankhwala limathiridwa mwachangu, gawo lomwe limalumikizidwa ndi ACE limakhalabe m'magazi kwa nthawi yayitali.

Zizindikiro zogwiritsidwa ntchito

Lisinopril ndi mankhwala ochizira matenda otsatirawa:

• ochepa matenda oopsa;
• kulephera kwa mtima;
• AMI odwala odwala khola hemodynamic magawo;
• nephropathy yomwe imayambitsidwa ndi zovuta za metabolic mu mellitus osagwirizana ndi insulin, kuthamanga kwa magazi.

Mankhwalawa amalembera mtima kulephera.

Ndi mavuto ati

Chithandizo cha angiotensin-converting enzyme inhibitors, chomwe chimaphatikizapo lisinopril, chimawonetsedwa kwa odwala onse omwe ali ndi matenda oopsa. Amawalemba onse ndi kuchepa kwamphamvu kwa kuthamanga kwa magazi, komanso ndiwofatsa komanso matenda oopsa.

Mlingo woyamba wa matenda oopsa umaonedwa kuti ndiwowonjezereka wopsinjika wa systolic mpaka 140-159 mm Hg. ndi kukakamiza kwa diastolic mpaka 90-99 mm Hg

Tazindikira kuti magazi akuchulukirachulukirachulukira, musadzinamize. ACE zoletsa ayenera kuyikidwa ndi dokotala.

Contraindication

Lisinopril sanalembedwe milandu iyi:

• wodwalayo ali ndi hypersensitivity yogwira ntchito kapena zinthu zina zomwe zimapangika;
• angioedema;
• bilteryal aimpso mtsempha wamagazi;
• myocardial infarction;
• kusakwanira kwa bcc;
• Cardiogenic mantha;
• odwala pambuyo impso;
• kulephera kwaimpso;
• kuchepa kwa aortic lumen;
• matenda oopsa a mtima;
• mitral valavu stenosis;
• hyperaldosteronism.

Amakanizidwa kuti amwe mankhwala osokoneza bongo.

Momwe mungatengere Lisinopril 20

Chidachi chimagwiritsidwa ntchito nthawi 1 patsiku. Kumwa mankhwalawa sikudalira nthawi yakudya. Piritsi imatengedwa m'mawa.

Mlingo ndi nthawi ya maphunzirowa amasankhidwa ndi adokotala, poganizira zomwe wodwala aliyense ali nazo. Mkhalidwe wa impso, mankhwala omwe amamwa, komanso kuchuluka kwa kuchuluka kwa magazi kumatengedwa.

Mlingo woyamba wa tsiku ndi tsiku ndi 2,5 mg. Kuwonjezeraku kumatha kuchitika pambuyo pa masabata a 2-4, pomwe zotsatira za mankhwala zikuwoneka. Mlingo umatha kuchuluka mpaka mankhwalawo atha kuwongolera kuthamanga kwa magazi. Mlingo wovomerezeka tsiku lililonse ndi 40 mg.

Kulephera kwa mtima, mankhwalawa amayamba ndi mlingo wofanana tsiku lililonse, womwe pambuyo pake umatha kufika pa 20 mg.

Mu infalction pachimake myocardial, 5 mg wa lisinopril ndi mankhwala. Pambuyo pake, mlingo umakwera mpaka mu 10 mg. Mankhwalawa amatha kwa milungu 6. Ngati wodwala systolic magazi ali pansi pa 120 mm Hg, mlingo umachepetsedwa ndi 2 times.

Mlingo ndi nthawi ya maphunzirowa amasankhidwa ndi adokotala, poganizira zomwe wodwala aliyense ali nazo.

Ndi matenda ashuga

Kukhazikitsidwa kwa mlingo wocheperako tsiku lililonse kumalimbikitsidwa. Kuwonjezeka kumachitika moyang'aniridwa ndi dokotala.

Odwala omwe ali ndi matenda amtundu wa 2 komanso nephropathy oyambira gawo limalandira 10 mg ya mankhwalawa. Mlingo wapamwamba tsiku lililonse ndi 20 mg.

Zotsatira zoyipa

Nthawi zambiri, mankhwalawa amalekerera mosavuta. Zizindikiro zodziwika bwino ndizakuti: hypotension, kuchuluka kwa mtima, kusiya kudziwa, kapena kugwa kwamitsempha. Mawonekedwe olimbana ndi anaphylaxis kapena kutupa kwamaso kumachitika.

Matumbo

Mankhwala, zizindikiro zotsatirazi zingachitike:

• kamwa yowuma
• kusintha kwa chopondapo;
• kutulutsa;
• matenda a anorexia;
• kuphwanya kwa chiwindi ntchito;
• hepatitis;
• kapamba
• nseru
• kusanza
• kupweteka kwam'mimba.

Lisinopril angayambitse mavuto ogona.

Pa chithandizo, wodwala amatha kudandaula za kupweteka kwam'mimba.

Lisinopril angayambitse kutulutsa.

Pakumwa mankhwala a lisinopril, munthu amatha kukwiya.

Nthawi zina, mankhwalawa amayambitsa mseru komanso kusanza.

Pa chithandizo ndi mankhwalawa, wodwalayo amatha kuda nkhawa pakamwa pouma.

Hematopoietic ziwalo

Mawonetsedwe otsatira a pathological ndiwotheka:

• thrombocytopenia;
• kuchepa kwa maselo oyera;
• kuchepa magazi
• pancytopenia;
• matenda a mwanabele;
• eosinophilia.

Pakati mantha dongosolo

Atha kuyankha pa mankhwalawa ndikuwoneka ngati awa:

• zosokoneza tulo;
• kusokonekera;
• kugona
• mavuto okhumudwitsa;
• chisokonezo cha chikumbumtima;
• tinnitus;
• zotumphukira neuropathy;
• kukokana
• masomphenya apawiri
• kugwedezeka
• paresthesia;
• mgwirizano wolakwika.

Kuchokera ku kupuma

Zizindikiro zotsatirazi zingachitike:

• kutsokomola
• kutupa kwa bronchi;
• mphumu
• sinusitis
• rhinitis;
• hemoptysis;
• kuphipha kwa minofu yosalala ya bronchi;
• kuvutika kupuma.

Pa mankhwala ndi lisinopril, munthu amatha kugona.

Nthawi zina, tinnitus imachitika.

Mavuto okhumudwa nawonso samachotsedwa pakumwa mankhwala ndi Lisinopril.

Pa gawo la kupuma kwamphamvu, zizindikiro zam'mbali zimawonekera kudzera kutsokomola.

Lisinopril angayambitse sinusitis.

Mankhwala angayambitse kupuma movutikira.

Lisinopril amatha kuyambitsa alopecia.

Pa khungu

Khungu limatha kuyankha kuthandizidwa ndi mawonekedwe:

• hyperhidrosis;
• chidwi cha UV rays;
• zotupa;
• masinthidwe a psoriasis;
• stratization wa misomali;
• alopecia;
• pemphigus;
• erythema;
• dermatitis.

Kuchokera ku genitourinary system

Zitha kuwonekera:

• oliguria;
• anuria
• kutupa kwa impso;
• proteinuria;
• Arrester;
• kutsitsa kugonana poyendetsa;
• gynecomastia.

Dongosolo la Endocrine

Zizindikiro za matenda ashuga ndizotheka.

Zizindikiro za matenda ashuga ndizotheka.

Malangizo apadera

ACE inhibitors angayambitse hyperkalemia ndi kuchepa kwa masodium m'magazi. Izi zimafunikira kuwunikira kwakanthawi kwamawonekedwe a electrolyte panthawi yamankhwala.

Gwiritsani ntchito mu ukalamba

Mulingo woyenera wambiri wa mankhwalawa m'madzi a m'magazi okalamba umapitirira chizindikiro chofananira mwa odwala achinyamata ndi 1.5-2 nthawi. Izi zitha kukhala chifukwa chokonza mankhwalawa tsiku lililonse.

Zokhudza mphamvu pakuwongolera njira

Chenjezo liyenera kuchitidwa pamene mukumwa mankhwalawa, chifukwa lingayambitse kuoneka kwa matenda amanjenje. Kuphwanya komwe kungachitike poyendetsa kayendedwe ka kayendedwe kazinthu ndikuwonetsetsa, zomwe zimatha kubweretsa zovuta pamagalimoto oyendetsa ndi njira zovuta.

Kuphwanya komwe kungachitike poyendetsa kayendedwe ka kayendedwe kazinthu ndikuwonetsetsa, zomwe zingayambitse zovuta pakuyendetsa.

Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere

Chithandizo ndi lisinopril chimapundulidwa pa mimba. Kukhazikitsidwa kwa mankhwala kwa akazi omwe akumakhazikika sikulimbikitsidwa.

Kulemba Lisinopril kwa ana 20

Kafukufuku wachitika pa kugwiritsa ntchito mankhwalawa mankhwalawa hypotension ana a zaka 6-18. Kuchuluka kwa mayamwa m'gululi kuli pafupifupi 30%. Chiwerengero chokwanira chokwanira mu ntchito ya impso ndi chiwindi sichimasiyana ndi zomwe zimachitika mwa akulu.

Popanda kutsutsana, lisinopril imatha kuperekedwa kwa ana.

Bongo

Mankhwala osokoneza bongo amatha kutha, kugundika, kusalinganika kwa electrolyte, kusiya kukumbukira, komanso kupweteka kwambiri kwaimpso.

Ngati mankhwala osokoneza bongo amakayikiridwa, ndikofunikira kutsuka m'mimba mwa wodwalayo, kupereka mankhwala opatsirana. Ngati wodwala ali ndi zovuta zam'matenda, kuperekera kuchipatala ndikofunikira. Mu chipatala, muyenera kuwunika ntchito zamtima ndi zam'mapapo, kubwezeretsa bcc, kusintha mawonekedwe a electrolyte.

Kugwiritsa ntchito mankhwala osokoneza bongo kwambiri kungachititse kuti musamadzindikire.

Kuchita ndi mankhwala ena

Kugwiritsa ntchito kwa lisinopril kumaphatikizidwa ndi:

1. Aliskiren - chifukwa choopsa cha kufa.
2. Estramustine - imawonjezera chiopsezo champhamvu yokhudzana ndi chitetezo chamthupi.
3. Baclofen - imapangitsa zotsatira za lisinopril, zomwe zingayambitse kuchepa kwambiri kwa magazi.
4. Sympathomimetics - kuchepetsa mphamvu ya mankhwala.
5. Tricyclic antidepressants.
6. Ma antipsychotic.
7. Mankhwala osokoneza bongo.

Ndi chisamaliro

Kuphatikizika kwa lisinopril ndi potaziyamu kosakhalitsa kungapangitse kuwonjezeka kwa gawo la chinthu ichi m'magazi. Kuphatikiza koteroko kumafunikira kuwunikira kwakanthawi kwamiyezo yama electrolyte.

Mankhwala amatha kuperewera kwa hypoglycemic zotsatira za mankhwala omwe amamwa chifukwa cha matenda ashuga. Kuchepetsa shuga m'magazi kungafune kusintha kwa mlingo.

Kumwa mowa sikulimbikitsidwa kwa anthu omwe ali ndi matenda oopsa.

Kuyenderana ndi mowa

Kumwa mowa sikulimbikitsidwa kwa anthu omwe ali ndi matenda oopsa. Kuphatikiza ndi ACE inhibitors kumatha kukulitsa zovuta zoyipa.

Kuphatikizidwa ndi mankhwala omwe si a antiidal anti-yotupa kumachepetsa mphamvu ya mankhwalawa. Pakhoza kukhalanso kuwonongeka mu ntchito ya impso mpaka kukulitsa kusakwanira kwa ziwalozi.

Analogi

Zofananira za mankhwalawa ndi:

• Aurolyza;
• Vitopril;
• Dapril;
• Diroton;
• Zonixem;
• Irume;
• Lysigamm;
• Lisighexal;
• Scopril;
• Solipril.

Maholide a Lisinopril 20 ochokera ku malo ogulitsa mankhwala

Amamasulidwa malinga ndi zomwe dokotala wanena.

Kodi ndingagule popanda kulandira mankhwala?

Ayi.

Mtengo

Zimatengera malo ogula.

Zosungidwa zamankhwala

Iyenera kusungidwa kutentha osapitirira + 25 ° C.

Tsiku lotha ntchito

Osapitilira zaka zitatu kuchokera tsiku lomwe adatulutsa.

Mankhwala amapezeka pamankhwala.

Wopanga Lisinopril 20

Zimapangidwa ndi kampani ya Ratiopharm.

Ndemanga za Lisinopril 20

Madokotala

Maxim Pugachev, katswiri wa zamtima, Moscow

Lisinopril ndiwothandiza ku matenda oopsa. Ndimapereka kwa odwala anga onse monga monotherapy, komanso kuphatikiza ndi othandizira ena. Kwa odwala omwe ali ndi mawonekedwe owopsa a matendawa, ndimalimbikitsa chithandizo chamankhwala othandizira kuphatikiza ndi lisinopril. Ndi kuyang'aniridwa moyenera ndi dokotala, njira yothandizira mankhwalawa sikugwira ntchito kokha, komanso ndiyotetezeka. Zonse zili ndi kusankha koyenera kwa mankhwala.

Nthawi zambiri ndimagwiritsa ntchito lisinopril + hydrochlorothiazide 12.5 mg regimen. Ndikofunika kungokumbukira kuti diuretic imachotsa sodium, yomwe ingafunike kuwunika zomwe zili m'magazi. Izi zimachitika pongokhazikitsa kuchuluka kwa mchere mu chakudya.

Alla Galkina, katswiri wa zamtima, ku Moscow

Mankhwala odziwika kwa dokotala aliyense. ACE inhibitors amalembedwa kwa anthu onse omwe ali ndi matenda oopsa, chifukwa amathandizira kuyendetsa magazi. Iyi ndiye njira yokhayo yotuluka, popeza ndizosatheka kuchiritsiratu matendawa.

Kutenga Lisinopril ndikwabwino. Piritsi limodzi lokha patsiku lithandiza kukhalabe ndi magazi. Muyenera kusankha mlingo woyenera. Nthawi zina ndikofunikira kupereka mankhwala ochulukirapo, koma pokhapokha pazovuta kwambiri.

Ndi zoletsedwa kuchita phwando munthawi yomweyo ndi Aliskiren, monga pamakhala chiopsezo cha kufa.

Odwala

Pavel, wazaka 67, Ufa

Ndakhala ndikuvutika ndi mtima nthawi yayitali komanso matenda oopsa kwa nthawi yoposa chaka chimodzi. Ndinayesa mankhwala ambiri, koma sindinapeze kalikonse kabwino kuposa Lisinopril. Mapiritsi otsika mtengo omwe amathandizira kuthamanga kwa magazi. Musazengereze kugula mankhwalawa, ma analogu achilendo siwabwinonso. Uku ndikutulutsa ndalama kosavuta.

Zhanna, wazaka 54, Irkutsk

Ndili ndi matenda oopsa a digiri yachiwiri. Anayamba kuzindikira zizindikiro zaka 3 zapitazo, pomwe mutu, chizungulire, kufooka, palpitations zinaonekera. Ndidapita kwa dotolo yemwe adandipeza ndikuwonetsa chithandizo. Kuyambira pamenepo ndakhala ndikutenga Lisinopril. Chipangizochi chikugwirizana ndi ntchito yake, sindikuwona zotsatira zoyipa zilizonse. Ndimapereka mayeso onse munthawi yake ndikupita kwa dokotala kuti ndikaonane. Pomwe mankhwalawa amakhutira kwathunthu.

Gennady, wazaka 59, Samara

Ndimatenga Lisinopril pafupifupi miyezi itatu. Njira ya chithandizo inayamba atangopeza dokotala. Mankhwalawa, 2 times amayenera kuchuluka kwa mankhwalawa. Tsopano kutenga 10 mg patsiku. Ndakhala ndikutsatira mankhwalawa kwa milungu iwiri tsopano. Kupsinjika kunabwereranso kwazonse. Ndikukhulupirira kuti mankhwalawa azithandizira kupitilirabe moyenera komanso mtsogolo.