Matenda a hyperlipidemia nthawi zambiri amakhala asymptomatic ndipo wodwalayo sazindikira kuti aliko. Komabe, matendawa amatha kubweretsa zotsatira zoyipa mthupi la munthu, kuphatikizapo imfa, chifukwa kuwonjezereka kwa cholesterol kumabweretsa mawonekedwe a atherosclerotic plaques ndipo, chifukwa, kugunda kwa mtima kapena sitiroko.
Kuti mupewe komanso kuchepetsa mwayi wokhala ndi matendawa, muyenera kumwa mankhwala monga Crestor. Mankhwalawa aposachedwa amagwiritsidwa ntchito kuti njira zamtundu wa metabolic zisinthike ndipo amapezeka piritsi.
Pali mitundu ingapo ya mankhwalawa omwe amasiyana wina ndi mzake kutengera ndi zomwe zimagwiritsidwa ntchito, zomwe ndi:
- wachikasu wokhala ndi chizindikiro cha ZD4522 5. Ali ndi mawonekedwe ozungulira ndipo ali ndi magalamu asanu a rosuvastatin yogwira;
- mtundu wa pinki. Fomu ya piritsi ndi yofanana, yolembedwa ZD4522 10 ndi mamiligalamu 10 a chinthu chogwira;
- mapiritsi ZD4522 20, momwe kuchuluka kwa rosuvastatin ndi mamilimita 20;
- mapiritsi a oval pinki ZD4522 okhala ndi rosuvastatin wokwanira, 49 mg.
Mutha kugula mankhwalawa kapena mankhwala ake muchipatala pokhapokha ngati dokotala wakulemberani mankhwala oyenera.
Mfundo zoyenera kuchitira mankhwalawa
Pharmacodynamics ya Krestor ndikuti imayambitsa enzyme yapadera yomwe imayang'anira kupanga cholesterol precursor kapena mevalonate.
Chithandizo chogwira mankhwalawa chimagwira mwachindunji m'chiwindi, chomwe chimapanga cholesterol. Enzyme iyi imathandizira kuchepetsa kupanga ma lipoprotein otsika kwambiri, omwe amathandiza kuchepetsa kuchuluka kwa cholesterol m'thupi, komanso triglycerides.
Kuphatikiza apo, cholesterol yapamwamba imakwera. Mankhwalawa ndi othandiza kwa odwala azaka zilizonse, jenda ndi mtundu. Ndemanga zambiri za ogwiritsa ntchito zikuwonetsa kuti kugwiritsa ntchito Krestor kumawonekera kale mu sabata yoyamba ya maphunzirowa, pomwe luso lokwanira limakwaniritsidwa mukamaliza maphunzirowa mu masabata 2-4 ogwiritsa ntchito mosalekeza.
Mtanda, mosiyana ndi mawonekedwe ake ambiri, umakhala ndi vuto lochepa pa chiwindi cha munthu. Ndikofunika kuphatikiza kugwiritsa ntchito kwake ndi zakudya zapadera, komanso mankhwala ena omwe amatsitsa kuchepetsa mafuta m'thupi.
Mankhwala a pharmacokinetic a mankhwalawa ndi awa:
- Mulingo woyamwa. Kuchuluka kwa statin kumawonekera m'magazi pambuyo pa maola 5, mutatha kugwiritsa ntchito mankhwalawa.
- Pogawa thupi. Gawo lofunikira kwambiri la Krestor ndi chiwindi, chomwe chimapanga mafuta m'thupi. Voliyumu yogawa ndi 134 malita.
- Muli kuchuluka kwa kagayidwe. Kwa Krestor, ili pafupifupi 10%.
- Munjira yotulutsira. Kuchuluka kwa mankhwala omwe amachotsedwa m'thupi ndi pafupifupi 90% pasanathe maola 19 oyang'anira.
Zaka za wodwalayo, komanso jenda, sizikhala ndi mphamvu iliyonse pamankhwala a pharmacokinetic.
Muyenera kulabadira kupezeka kwa matenda a impso. Chifukwa chake, kufatsa komanso kufatsa kwamankhwala ochepa sikumakhudza kuchuluka kwa ma statin, pomwe akuuma kwambiri, kuchuluka kwa rosuvastatin kumawonjezeka katatu.
Kukhalapo kwa ma pathologies a chiwindi sikuti sikukhudza kugwiritsa ntchito mankhwalawa.
Krestor - fanizo la mankhwala ndi zikugwiritsira ntchito
Analogue yotsika mtengo kapena yolowa m'malo mwa mankhwalawo, ngati wodwalayo wasankha kuigwiritsa ntchito, amafunika kusamala.
Mwanjira ina, odwala omwe aganiza kuti asankhe mankhwalawo ngati ali ndi mankhwala osokoneza bongo ayenera kuonana ndi dokotala, kapena kudziwa zomwe zikuwonetsedwa ndikuwonetsa.
Poyamba, Krestor amalimbikitsa kugwiritsa ntchito:
- ndi hypercholesterolemia;
- monga kupewa kunjenjemera ndi matenda a mtima;
- ndi hypercholesterolemia yosakanikirana;
- anthu omwe ali ndi atherosulinosis;
Kuphatikiza apo, tikulimbikitsidwa kugwiritsa ntchito mankhwalawa pamaso pa hypertriglyceridemia.
Malangizo ogwiritsira ntchito mankhwalawa
Krestor, monga mankhwala ena aliwonse, ali ndi pulogalamu yakeyake ndi Mlingo wogwiritsira ntchito.
Monga lamulo, ndi dokotala yemwe amasankha kuchuluka kwa mankhwala omwe wodwalayo ayenera kugwiritsa ntchito. Amachita izi pamaziko a kafukufuku ndi zotsatira za kusanthula.
Kuphatikiza apo, momwe wodwalayo alili komanso kupezeka kwa matenda opatsirana amakhudzidwa.
Chifukwa chake, Krestor ayenera kumwedwa motere:
- Pogaya piritsi la mankhwalawa.
- Nthawi yoyenera kwambiri kuvomerezedwa imadziwika kuti ndi yamadzulo polumikizana ndi kuchuluka kwa mafuta a cholesterol m'thupi.
- Kudya sikukhudza phindu la mankhwalawa.
- Asanayambe kumwa mankhwalawo, wodwalayo amalimbikitsidwa kuti azitsatira zakudya zochepa zamafuta.
- Poyamba, ndikofunikira kumwa mankhwalawa kuchuluka kwa 5-10 g patsiku. Komabe, Mlingo wa mankhwalawa umasankhidwa yekhayo komanso dokotala. Pokhapokha patatha mphamvu ya kuchuluka kwa mankhwala omwe atengedwa, amatha kuwonjezereka mpaka 20 milligram, koma pakatha mwezi umodzi. Kuchuluka kwa ma milligram 40 kumayikidwa pokhapokha ngati chiwopsezo cha matenda amtima chakwera kwambiri. Odwala omwe ali ndi vuto lalikulu la hypercholesterolemia amayenera kuyang'aniridwa ndi madokotala pafupipafupi kuti apewe zoyipa.
Ngati wodwalayo ali ndi mankhwala osokoneza bongo mopambanitsa, m'malo mwakugwiritsira ntchito mankhwala ena alionse, njira zothandizira zimagwiritsidwa ntchito.
Zotsatira zoyipa mukamagwiritsa ntchito Crestor
Monga lamulo, ngati wodwalayo atsatira ndendende malingaliro onse omwe amamwa mankhwalawa kapena mankhwalawa, amakwaniritsa kupewa zovuta zina. Zomwezo zimapita kwa Krestor.
Ngakhale zili choncho, malangizo a mankhwalawa amafotokoza momveka bwino zoyipa zomwe zingachitike.
Zambiri pazotsatira izi zidapezeka pambuyo pa maphunziro azachipatala angapo.
Zina mwazotsatira zoyipa izi ndi:
- kusokonezeka kwa m'mimba thirakiti, kupweteka pamimba, kapamba, hepatitis, ndi zina;
- thrombocytonepia;
- mawonekedwe a chifuwa ndi kufupika kwa mpweya;
- matenda a chapakati mantha dongosolo;
- mawonekedwe amitundu yosiyanasiyana ya totupa, urticaria ndi kuyabwa;
- kuwoneka kwa puffness ndi hypersensitivity;
- matenda a musculoskeletal system;
- proteinuria;
- mawonekedwe a shuga;
- kukhumudwa, etc.
Kuti mupewe kuwoneka ngati mbali yoyipa, muyenera kudziwa momwe zimaponderezedwera kuti mugwiritse ntchito izi:
- Pamaso pa kudziwa kwambiri zomwe zimagwiritsidwa ntchito.
- Pankhani ya pachimake mawonekedwe a chiwindi matenda ndi mawonekedwe owoneka aimpso kulephera.
- Ndili ndi mbiri ya myopathy.
- Pankhani ya pakati ndi mkaka wa m`mawere.
- Pamaso pakuwonetseratu kukula kwa myotoxic zotsatira.
Kuphatikiza apo, mulingo woyenera wa mankhwalawa wokwanira mamiligalamu 40 amatanthauza zinthu zotsatirazi:
- hypothyroidism;
- kukonzeratu matenda a minofu;
- uchidakwa;
- myotoxicity mogwirizana ndi kugwiritsa ntchito mankhwala ena;
Sizoletsedwa kugwiritsa ntchito rosuvastatin ndi ma fiber nthawi yomweyo.
Zofanizira zazikulu za Crestor
Mumsika wamakono wamankhwala, kuchuluka kwa mankhwala kumawonetsedwa. Komabe, monga lamulo, mankhwala oyambirirawo ndiokwera mtengo kwambiri ndipo si wodwala aliyense amene ali ndi mwayi wowagula.
Pankhaniyi, opanga ambiri adaganiza zoyambitsa ndi zoyambirira. Monga lamulo, kusiyana kwakukulu pakati pa mankhwalawa ndi mtengo.
Kuphatikiza apo, ndikofunikira kulingalira kuti mankhwala aliwonse kapena mtundu wake wa mankhwalawa uyenera kufotokozedwa ndi dokotala yemwe aziganizira zonse zomwe zimachitika pamatendawa komanso momwe wodwalayo alili.
Mwa ena odziwika bwino ndi awa:
- Akorta. Mnzake waku Russia. Ndizofanana mu kapangidwe kake, komanso m'zisonyezo zokugwiritsira ntchito. Amagwiritsidwa ntchito pamaphunziro ataliatali monga momwe afotokozera.
- Mertenil. Chofunikira chachikulu ndi rosuvastatin. Ndi analogue yakunja yomwe imagwirizana mu mankhwala ake ndi mankhwala oyamba. Kupangidwa ku Hungary ndikuthandizira kuchepetsa cholesterol. Mtengo - 510-1700 rubles.
- Rosistark. Chida chothandiza chomwe chimagulitsidwa pamtengo wotsika mtengo kwambiri. Musanagwiritse ntchito, tikulimbikitsidwa kuti muwerenge malangizo kuti muchepetse zovuta zomwe zimagwiritsidwa ntchito. Mtengo pa avareji umachokera ku 250 mpaka 790 rubles.
- Rosucard. Mnzake wina waku Russia. Zomwe zimagwiritsidwa ntchito ndizofanana, komanso kuchuluka kwa piritsi limodzi. Contraindicated ngati mukumvera kwambiri ntchito yogwira zosakaniza.
- Rosulip. Kugwiritsa ntchito mankhwalawa ndikofunikira pa hypercholesterolemia, hypertriglyceridemia, kuti muchepetse kupita patsogolo kwa atherosulinosis komanso kupewa matenda a mtima. Zimapangidwa ku Hungary ndipo zimawononga ma ruble 390-990.
- Roxer. Hypolipidemic mankhwala. Sitikulimbikitsidwa kugwiritsa ntchito nthawi yapakati, mukamayamwitsa, komanso ana osakwana zaka 18. Mtengo wapakati ndi ma ruble 440-1800 aku Russia.
- Tevastor Mankhwala omwe ayenera kugwiritsidwa ntchito kwa pafupifupi milungu 4 kuti muwonekere. Zimapangidwa ku Israeli ndipo zimagula ma ruble pafupifupi 350-1500.
- Novostat. Chofunikira chachikulu ndi atorvastatin. Mankhwalawa amapangidwa ku Russia.
Mtengo wa mankhwalawa ndiwosiyana ndipo umasiyana kuchokera ku ruble 500 mpaka 3000 kapena kuposerapo.
Ndemanga ya odwala ndi madokotala za Crestor
Malinga ndi lingaliro la madotolo aluso, Krestor adakhala mankhwala othandiza kwambiri omwe amathandiza kuchepetsa magazi m'thupi.
Odwala ambiri omwe akuchita nawo zokambiranazo, chizindikiro cha cholesterol chinayamba bwino patadutsa sabata limodzi, maphunziro atayamba.
Mapiritsi omwe ali pamsika wa mankhwalawa ndi apamwamba kwambiri, chifukwa chake kugwiritsa ntchito mankhwalawa ndikwapamwamba kwambiri. Monga lamulo, njira ya mankhwalawa sikuyambitsa mavuto.
Ponena za malingaliro a odwala, zimagwirizana mokwanira ndi malingaliro a madokotala. Nthawi zambiri, pamakhala malingaliro a odwala omwe adadwala matenda a stroko kapena a mtima.
Chifukwa chake, titha kunena kuti mankhwalawa ndi othandizadi. Zimangotengera nthawi kuti zizindikirazo zibwerere mwakale.
Ndingatenge ma statins ndikamuuza katswiri mu kanemayu pankhaniyi.
