Momwe mungagwiritsire ntchito mankhwala a Liprimar?

Matenda a mtima ndi zina mwazomwe zimayambitsa kufa ku Russia komanso padziko lonse lapansi. Pansi pa izi, kupewa matenda a mtima ndikofunikira. Mankhwala amapereka mitundu yambiri yamankhwala omwe amathandizira kuthetsa pathologies m'derali. Chimodzi mwa izo ndi mankhwala a Liprimar.

ATX

Khodi ya ATX yamankhwala ndi C10AA05. Zomwe zimagwira ndi atorvastatin (gulu la ma statins).

Liprimar, mankhwala omwe amachotsa matenda amtima wamatumbo ndikuwathandiza kupewa.

Kutulutsa mafomu ndi kapangidwe kake

Kuphatikizika kwa mapiritsi ndi ntchito yogwira ndi zina zothandizira.

Atorvastatin, woyimiriridwa ndi mchere wa calcium, amagwira ntchito ngati yogwira ntchito. Kuchuluka kwake piritsi lililonse kumatengera muyeso wa mankhwalawa (10 mg mpaka 80 mg).

Kuphatikiza kothandizidwaku ndi zinthu zambiri. Mulinso:

• lactose monohydrate;
• calcium carbonate;
• croscarmellose sodium;
• MCC;
• hydroxypropyl cellulose;
• polysorbate 80;
• magnesium wakuba;
• Opadra yoyera.

Mankhwala amapangidwa piritsi, komabe, amatha kukhala ndi mitundu ingapo. Mapiritsiwo ndi oyera komanso oyera ngati mawonekedwe, okutidwa ndi chipolopolo choyera pamwamba. Kuti mupeze mawonekedwe osavuta, mutha kusankha mapiritsi okhala ndi gawo la 10, 20, 40 kapena 80 mg.

Kuti mupeze mawonekedwe osavuta, mutha kusankha mapiritsi a Liprimar ndi mulingo wa 10, 20, 40 kapena 80 mg wa chinthu chomwe chikugwira ntchito.

Kuyika mankhwala - matuza omwe mapiritsi 7 kapena 10 adatsekeka. Mtolo wa makatoni ukhoza kukhala ndi matuza 2, 5, 8 kapena 10.

Zotsatira za pharmacological

Mankhwala ali ndi hypocholesterolemic ndi lipid-kutsitsa katundu.

Chofunikira chachikulu pa mapiritsiwo ndi atorvastatin, omwe amawerengedwa ngati mpikisano wosankha wa HMG-CoA reductase. Izi zimakhudzidwa ndikuwongolera kusintha kwa HMG-CoA kupita ku mevalonate. Mapiritsi amawonjezera kuchuluka kwa ma LDL receptors.

Mothandizidwa ndi atorvastatin, zosintha zotsatirazi zimachitika mthupi:

• m'magazi, kuchuluka kwa osachepera lipoproteins amachepetsa;
• kuchuluka kwa osachulukitsa lipoproteins ukuwonjezeka;
• zomwe triglycerides ndi apolipoprotein B zimachepa.

Pharmacokinetics

Pambuyo pakamwa, kuyamwa mwachangu kwa zinthu zomwe zimachitika kumachitika. Kuzindikira kwakukulu m'magazi kumatha kufikira pambuyo pa maola 1.5-2 pambuyo poti mankhwala alowa. The bioavailability wa thunthu ndiwambiri - pafupifupi 95-98%.

Mothandizidwa ndi yogwira pophika Liprimar, ndende ya kuchuluka kachulukidwe lipoproteins mu magazi ukuwonjezeka.

Kumangiriza kwa mapuloteni amwazi kumakhalanso pamlingo wokwera kwambiri (pafupifupi 98%).

Atorvastatin ndi ma metabolites ake amachotsedwa makamaka pachiwindi. Nthawi yochuluka yochotsa ndi maola 28.

Zizindikiro zogwiritsidwa ntchito

Pali zifukwa zingapo zomwe adotolo amatha kukupatsirani mankhwala awa.

Odwala ndi hypercholesterolemia:

1. Kuphatikiza chakudya. Mankhwala amathandizira kukwaniritsa zotsatira zofunika ngati vuto lakudya. Matendawa atha kuphatikizaponso zotsatirazi: chachikulu hypercholesterolemia, heterozygous kapena mtundu wosakanizika wa matenda. Pankhaniyi, kuchepa kwa LDL-C, cholesterol, ndi triglycerides kumatheka.
2. Monga chowonjezerapo chothandizira kuchepetsa lipid kapena ngati sizingatheke kugwiritsa ntchito njira zina zochizira. Izi ndi zothandiza mu banja homozygous hypercholesterolemia.

Pofuna kupewa matenda a mtima dongosolo zotchulidwa:

1. Odwala omwe ali pachiwopsezo cha kukhazikitsa mtima wa mtima.
2. Kuti mupewe kugunda kwa mtima, mikwingwirima yam'magazi ndi kukula kwa zovuta pachimake ndi angina pectoris. Potere, mankhwalawa amalembedwa kwa odwala omwe ali ndi matenda a mtima komanso matenda ena a mtima.

Contraindication

Mankhwalawa ali ndi zotsutsana zingapo. Izi zikuphatikiza:

• kusalolera kwa munthu ena paz kapangidwe kake monga mapiritsi;
• mimba ndi nthawi yoyamwitsa (ngati mankhwalawa adalembedwa, kuyamwitsa kumalimbikitsidwa kusokonezedwa);
• lactose tsankho, lactase akusowa (kobadwa nako);
• shuga-galactose malabsorption;
• kwambiri matenda a chiwindi, kuphatikizapo ntchito yayikulu ya hepatic transaminases;
• ana osakwana zaka 18 (kupatula pamenepo ndi kuzindikira kwa hemerzlegous hypercholesterolemia, pomwe mankhwalawa amalembedwa kwa ana azaka 10).

Liprimar sinafotokozeredwe ma pathologies a chiwindi.

Momwe mungatenge Liprimar

Mapiritsiwo adapangira pakamwa. Potere, mankhwalawa amayenera kutsukidwa ndi madzi. Kudya sikukhudza kuthamanga komanso kuyamwa kwa zinthu zomwe zimagwira, ndiye kuti mapiritsi amatha kudya nthawi iliyonse tsiku lisanachitike kapena mutatha kudya.

Atorvastanin ayenera kuikidwa milandu ngati zakudya zapadera, zolimbitsa thupi ndi mitundu ina ya chithandizo sizinabweretse vuto.

Mapiritsi amatengedwa 1 nthawi patsiku, pamene mlingo umatha kusiyanasiyana 10 mg mpaka 80 mg. Mlingo wapamwamba wa tsiku lililonse ndi voliyumu ya 80 mg ya atorvastatin. Kwa wodwala aliyense, mulingo woyenera kwambiri umasankhidwa payekha malinga ndi matenda ake komanso mitundu ina ya mankhwalawo.

Nthawi zina, mankhwala a atorvastatin omwe amawonjezereka pang'onopang'ono muyezo watsiku ndi tsiku amalimbikitsidwa. Kuphatikiza apo, kuwonjezeka kulikonse kwatsatanetsatane kumafunikira kuwunika kwa wodwalayo (mawonekedwe a magazi, chiwindi ndi impso).

Ndi matenda ashuga

Malinga ndi zotsatira za kafukufuku, HMG-CoA reductase inhibitors nthawi zina imachulukitsa kuchuluka kwa shuga m'magazi a m'magazi. Odwala omwe ali pachiwopsezo chotenga matenda a shuga amatha kukhala ndi hyperglycemia.

Nthawi yomweyo, madotolo amawona kuti pafupipafupi zochitika ngati izi ndizochepa, ndipo phindu la mankhwala a Liprimar limaposa zoopsa zomwe zingachitike. Chifukwa chake, odwala matenda a shuga komanso omwe ali pachiwopsezo ayenera kumwa mankhwalawa moyang'aniridwa ndi dokotala. Amafunikira kusintha kwa Mlingo ndi kuyezetsa magazi pafupipafupi.

Odwala omwe ali ndi matenda ashuga amatenga Liprimar moyang'aniridwa ndi dokotala. Amasintha kusintha kwa magazi ndi kuyezetsa magazi pafupipafupi.

Kodi ndizotheka kugawa pakati

Piritsi siyikulimbikitsidwa kuti igawidwe pakati. Izi zitha kufotokozedwa ndi kukhalapo kwa chipolopolo, chomwe chimalepheretsa kusungunuka kwazomwe zimagwira.

Chofunikira ndikupezeka kwa mapiritsi okhala ndi mitundu yosiyanasiyana. Izi zimapangitsa kukhala kosavuta kusankha njira yoyenera popanda kufunika kogawika.

Zotsatira zoyipa

Zotsatira zoyipa zakumwa zimatha kuthana ndi ziwalo zosiyanasiyana. Kuwonetsedwa pang'ono kwa zizindikiro ndizotheka m'masiku oyambirira a chithandizo. Nthawi zambiri si nthawi yothana ndi mankhwala osokoneza bongo. Ndi zizindikiro zazikulu, mankhwalawo amathetsedwa, ndipo ngati ndi kotheka, amaloledwa ndi wina.

1. Kuchokera kumbali ya dongosolo la minofu ndi mafupa, kupweteka kumachitika kawirikawiri m'miyendo, arthralgia ndi myalgia, kupweteka kumbuyo, kutupa kwa mafupa, kufooka kwa minofu.
2. Zotsatira zoyipa za ziwalo zam'maganizo ndizotheka. Odwala amawona mawonekedwe a chophimba pamaso, tinnitus, kuphwanya kwamtundu wakomedwe.
3. Mwina chitukuko cha hyperglycemia ndi hypoglycemia.
4. Amadera akutali akuwoneka kuti alibe mphamvu amafotokozedwa.

Matumbo

Odwala ena amati dyspepsia, nseru, kugonja, kudzimbidwa. Zomwe zimapezeka kwambiri ndi kupweteka kwa epigastric, kupindika, kusanza, ndi kapamba.

Hematopoietic ziwalo

Milandu ingapo ya thrombocytopenia afotokozedwa.

Pakati mantha dongosolo

Zotsatira zoyipa zoyambira mkatikati mwa mitsempha ya m'mimba ndizosokoneza mutu komanso kugona. Chizungulire, kufooka, paresthesia zimawonekera kawirikawiri. Pali zonena za zotumphukira za mitsempha ndi kuwonongeka kwa kukumbukira.

Kuchokera kwamikodzo

Mwina chitukuko cha aimpso kulephera, zotumphukira edema.

Kuchokera ku kupuma

Zilonda zapakhosi ndi m'mphuno zimatha kuchitika. Milandu ingapo yodwala matenda am'mapapo.

Matupi omaliza

Momwe thupi limasokoneza mankhwalawa ndi chizindikiro cha hypersensitivity chimodzi kapena zingapo za kapangidwe kake. Zochitika zoterezi nthawi zambiri zimayendera limodzi ndi urticaria, zidzolo zakumaso, anaphylaxis, erythema multiforme exudative, kapena poid epermosis yoletsa.

Mukamagwiritsa ntchito Liprimar kuchokera kumbali ya minofu ndi mafupa, minyewa imakonda kupezeka m'miyendo, kutupa kwa mafupa.

Mukamalandira mankhwala a Liprimar, mavuto omwe amachitika pafupipafupi ndi mutu komanso kusokonezeka kwa tulo.

Potengera maziko a kutenga Liprimar, urticaria imatha kuchitika.

Malangizo apadera

Popewa zovuta, mankhwalawa amayenera kuperekedwa mosamala kwa matenda a impso ndi chiwindi. Kwa odwala okalamba, pakalibe zoopsa, kusintha kwa mankhwalawa sikofunikira.

Kuyenderana ndi mowa

Kuphatikiza pamodzi kwa mankhwalawa ndi mowa sikofunikira kwenikweni. Kuphatikiza apo, anthu omwe amamwa mowa mopitirira muyeso amalephera kudya atorvastatin. Izi zikufotokozedwa ndikuwonjezeka kwa ntchito ya hepatic transaminases. Muzovuta kwambiri, pamakhala chiopsezo cha kufa.

Zokhudza mphamvu pakuwongolera njira

Mankhwalawa samakhudza mwachindunji kuchuluka kwa zochita. Pankhaniyi, zoyipa monga chizungulire, tinnitus ndi kuona mwachidwi zimatha kuchitika pakumwa. Pazifukwa izi, madokotala amalimbikitsa kuti muyendetse mosamala.

Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere

Amayi samapatsidwa mapiritsi panthawi yoyembekezera komanso yoyamwitsa.

Kulemba Liprimar kwa ana

Mankhwalawa ali otsutsana mpaka wazaka 18, popeza chidziwitso cha kugwiritsa ntchito mankhwalawa mankhwalawa sichikwana. Kupatula apo ndi odwala omwe amapezeka ndi mabanja a heterozygous hypercholesterolemia. Zikatero, mankhwalawa amatha kugwiritsidwa ntchito pothandiza ana azaka 10. Mankhwalawa amachitika moyang'aniridwa ndi dokotala.

Bongo

Mlingo wovomerezeka tsiku lililonse ndi 80 mg wa atorvastatin. Pochulukitsa mlingo woyenera, kuwonjezeka kwa mavuto kumachitika. Palibe chithandizo chamankhwala pamilandu iyi, chifukwa chake chithandizo chamankhwala chimalimbikitsidwa. Odwala amayesedwa kuwongolera ntchito ya KFK ndi kuyesa kwa chiwindi chantchito. Hemodialysis siyothandiza chifukwa chomangira mankhwala kumapuloteni amwazi.

Kuchita ndi mankhwala ena

Mankhwalawa amagwiritsidwa ntchito ngati gawo la chithandizo chovuta, motero kuphatikiza kwa mankhwala ndikofunikira.

Kuphatikizana sikulimbikitsidwa

Chiwopsezo cha myopathy chimakwera kwambiri ndikugwiritsidwa ntchito nthawi imodzi ndi ma fibrate, cyclosporine, nicotinic acid, ezetrol, mankhwala antifungal ndi clarithromycin.

Ndi chisamaliro

Mothandizidwa ndi diltiazem, erythromycin, isoenzyme ya cytochrome CYP3A4, clarithromycin angakulitse kuchuluka kwa mankhwala mu plasma ya magazi.

Atorvastatin imatha kuchepetsa kuchuluka kwa mankhwala monga colestipol, aluminium hydroxide ndi magnesium hydroxide.

Atorvastatin imawonjezera ndende m'magazi a awa: ethinyl estadiol, digoxin, norethisterone.

Pazochitika zonsezi, kusintha kwa mankhwalawa kumafunikira.

Wopanga

Mankhwalawa amapangidwa ndi Pfizer Pharmaceuticals ElElSi.

Analogs of Liprimar

Mankhwala otsatirawa atha kuphatikizidwa ndi mndandanda wa mawonekedwe a mankhwala.

• Ator;
• Atoris;
• Anvistat;
• Chowonera;
• Atomax;
• Novostat;
• Atocord
• Torvazin;
• Lipona
• Lipronorm;
• Tulip;
• Crestor
• Torvacard
• Lipoford.

Tulip ndi analogue ya Liprimar.

Kupita kwina mankhwala

Zokonzekera za gulu la mankhwalawa zimagulitsidwa m'masitolo amakankhwala.

Kodi ndingagule popanda kulandira mankhwala?

Simungagule mapiritsi popanda mankhwala.

Mtengo

Mitengo imasiyanasiyana malinga ndi kuchuluka ndi mapiritsi:

• Mapiritsi a 10 mg (ma PC 100) - pafupifupi ma ruble 1600;
• 20 mg mapiritsi (100 ma PC.) - pafupifupi 2500 ma ruble .;
• 40 mg mapiritsi (30 ma PC) - pafupifupi 1100 ma ruble .;
• Mapiritsi a 80 mg (ma 30 ma PC) - pafupifupi ma ruble 1200.

Zokonzekera za gulu la mankhwalawa zimagulitsidwa m'masitolo amakankhwala.

Liprimar

Sungani mapiritsi m'malo osafikirika ndi ana pa kutentha kwa + 15 ... + 25 ° C.

Tsiku lotha ntchito

Kutalika kwa yosungirako - zaka 3.

Ndemanga pa Liprimar

Eugene, katswiri wazachipatala, wazaka 11 zaku Moscow

Nthawi zambiri ndimapereka mankhwalawa kwa odwala omwe ali ndi matenda a mtima komanso kuchepetsa chiopsezo cha mtima. Mankhwalawa adachitapo kafukufuku wambiri wotsimikiziridwa, pali umboni wa kugwira ntchito kwake. Chimodzi mwazinthu zabwino zakugwiritsa ntchito ndikulekerera kwake, zotsatira zoyipa ndizochepa. Choyipa chake ndiye mtengo wokwanira wa mankhwala pogwiritsa ntchito nthawi yayitali.

Lidiya, wazaka 56, Yaroslavl

Anadwala matenda amtima, pambuyo pake dotolo adayala mapiritsi apadera kuti alepheretse kuyambitsanso. Mapiritsiwo ndi okwera mtengo. Ndimamwa piritsi limodzi kamodzi patsiku, monga adokotala adanenera. Sindingaweruze bwino pakadali pano, koma palibe zotsatira zake.

Vitaliy, wazaka 42, Pskov

Anandipeza ndi cholesterol yayikulu. Ndinapitiliza kudya kwa nthawi yayitali, koma sindinathe kutsitsa zizindikilozo. Cheke chotsatira, mapiritsi awa adalembedwa. Ndinayamba kuvomera. Mankhwalawa ndi abwino, chifukwa muyenera kumamwa kamodzi patsiku. M'mawa ndidatenga piritsi ndikupita ku ntchito. Kuyesedwanso posachedwa, cholesterol yachepa pang'ono.