Kuti achepetse kuchuluka kwa shuga m'magazi, mankhwala osiyanasiyana amagwiritsidwa ntchito, omwe akuphatikizapo Minidiab. Chipangizocho chili ndi contraindication ndi zoyipa, chifukwa musanagwiritse ntchito ndikofunikira kuphunzira malangizo.
Dzinalo Losayenerana
INN ya mankhwala ndi Glipizide (Glipizide).
Kuti achepetse kuchuluka kwa shuga m'magazi, mankhwala osiyanasiyana amagwiritsidwa ntchito, omwe akuphatikizapo Minidiab.
ATX
Chogulitsachi chili ndi nambala yotsatirayi ya ATX: A10BB07.
Kutulutsa mafomu ndi kapangidwe kake
Kutulutsidwa kwa mankhwalawa kumachitika mwa mapiritsi a 5 mg, oikidwa zidutswa 15. pakukumata matuza. Phukusi la makatoni lili ndi matuza awiri. Glipizide imagwira ntchito ngati mankhwala osokoneza bongo.
Zotsatira za pharmacological
Mankhwala ndi hypoglycemic wothandizira. Zimathandizira kumasula insulini yomwe imapezeka m'maselo a pancreatic beta. Chifukwa chogwiritsidwa ntchito pamimba yopanda kanthu kwa odwala omwe ali ndi mitundu yochepa komanso yolimba kwambiri ya shuga, amachepetsa kuchuluka kwa hemoglobin wa glycosylated komanso kuchuluka kwa shuga m'magazi.
Pa mankhwala, pali kuwonjezereka kwa kulolera kwa glucose, kutsimikizika kosafunikira kwamadzimadzi aulere komanso kuchepa kwa hyperglycemia ya pambuyo pa chakudya. Kukula kwa yankho la insulinotropic kumachitika mphindi 30 mutatha kumwa mankhwalawo. Mphamvu ya limodzi mapiritsi kumatenga maola 24. Zomwe zimagwiritsidwa ntchito sizikhudza mawonekedwe a lipid a madzi am'magazi.
Pharmacokinetics
Zigawo za mankhwalawa zimamwetsedwa kwathunthu komanso mwachangu m'mimba. Mukamadya, kuyamwa kwathunthu kumachepera ndi mphindi 40. Zokwanira zomwe zimapezeka m'magazi zimatheka pambuyo pa maola 1-3. Mankhwalawa amachotsedwa mu mkodzo mwanjira ya metabolites.
Zizindikiro zogwiritsidwa ntchito
Mankhwalawa amadziwikiridwa pamaso pa anthu osagwirizana ndi shuga omwe amatsalira a 2 shuga, pomwe sizingachitike chifukwa chokhala ndi zolimbitsa thupi komanso kudya zakudya zochepa zopatsa mphamvu, komanso matenda ashuga a shuga.
Contraindication
Kuchiza ndi Minidiab kuyenera kusiyidwa kwa odwala omwe ali ndi hypersensitivity ku zigawo za mankhwala, azimayi oyembekezera komanso oyembekezera, komanso odwala omwe amagwiritsidwa ntchito ndi insulin:
- chithandizo chachikulu cha opaleshoni;
- hyperosmolar chikomokere;
- mtundu 1 shuga;
- kuvulala kwambiri;
- matenda opatsirana;
- kuwotcha kwakukulu;
- matenda a shuga;
- matenda ashuga ketoacidosis.
Moyang'aniridwa ndi katswiri, mankhwalawa amatengedwa ndi odwala omwe ali ndi vuto lauchidakwa, chiwindi kapena matenda a impso, febrile syndrome, leukopenia ndi matenda am'mimba, omwe amasintha nthawi yomwe mankhwalawa amagwiritsidwa ntchito mthupi.
Kodi kutenga minidiab?
Mankhwala adapangira pakamwa. Ndikulimbikitsidwa kuyamba ndi mlingo wa tsiku ndi tsiku osapitilira 2,5-5 mg. Pambuyo pake, kuchuluka kwa zinthu kumawonjezereka mpaka 20 mg. Mapiritsi amatengedwa 2-4 pa tsiku musanadye zakudya zazikulu.
Pamaso pa matenda a shuga, ndikofunikira kugwiritsa ntchito mankhwalawa malinga ndi chiwembu chomwe adokotala adapereka atayeza mayeso athunthu.
Ndi matenda ashuga
Pamaso pa matenda a shuga, ndikofunikira kugwiritsa ntchito mankhwalawa malinga ndi chiwembu chomwe adokotala adapereka atapima mayeso athunthu komanso malingana ndi zotsatira za mayeso a zasayansi, momwe mulingo wa glycemia ndi glucosuria adatsimikizika.
Zotsatira zoyipa za Minidiab
Nthawi zina, thupi limayamba kugwiritsidwa ntchito mosatekeseka komanso mofatsa ndipo zimachitika pang'onopang'ono. Ngati zotsatira zoyipa zikuchitika, siyani chithandizo ndikufunsani katswiri.
Kuchokera ku ziwalo zamagetsi
Kuyankha pakumwa mankhwalawo kuchokera ku mphamvu kumawonekera mu mawonekedwe a chizungulire, kugona ndi kupweteka m'mutu.
Matumbo
Mankhwalawa amatha kuyambitsa nseru, kusanza, kukanika, kugona, kudzimbidwa, kumva kupsinjika pamimba, kuwoneka kwa zosafunika zamagazi m'matumba ndi cholestatic hepatitis.
Minidiab imatha kubweretsa m'mimba.
Hematopoietic ziwalo
Zotsatira zoyipa kuchokera ku ziwalo za hemopoietic ndi hemostatic system zimachitika mu mawonekedwe a arrhythmia, syncope, kutentha kwamphamvu, matenda oopsa, leukopenia, thrombocytopenia, agranulocytosis, hemolytic kapena aplastic anemia ndi pancytopenia.
Pakati mantha dongosolo
Ndi vuto lamanjenje, kumakhala mawonekedwe a chophimba pamaso, kupsinjika, kusokonezeka, kusokonezeka kwa mitsempha, zotupa za hemorrhage, paresthesia, hypersthesia, kupweteka m'maso ndi conjunctivitis.
Pa khungu
Zizindikiro zosasangalatsa kuchokera pakhungu zimawoneka ngati zotupa, urticaria, kuyabwa, erythema, photosensitivity ndi zotupa za maculopapular.
Zokhudza mphamvu pakuwongolera njira
Palibe chidziwitso pazakuipa kwa a Minidiab pa kasamalidwe kazinthu zovuta. Odwala omwe nthawi zambiri amayendetsa kapena kuchita zoopsa ayenera kusamala chifukwa zimachitika kuti chizungulire komanso hypoglycemia.
Malangizo apadera
Kuwongolera azachipatala kudzafunika kwa odwala omwe amamwa mankhwalawo nthawi yomweyo monga Insulin kapena kale asanagwiritse ntchito mankhwala ena ochepetsa shuga. Mlingo wa mankhwala a gulu lino la odwala amatsimikiza ndi kuchuluka kwa shuga m'magazi
Gwiritsani ntchito mu ukalamba
Odwala okalamba ayenera kumwa mapiritsi mosamala, popeza pali chiopsezo cha hypoglycemia.
Kupatsa ana
Sikulimbikitsidwa kugwiritsa ntchito mankhwalawa kuchiza ana, popeza palibe chidziwitso chokhudza chitetezo chake m'gulu ili la odwala.
Mukamapangira njira zochiritsira pogwiritsa ntchito Minidiab, kuyamwitsa kuyenera kutha.
Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere
Ngati mankhwalawa agwiritsidwa ntchito pakubala kwa mwana, ndiye kuti mapiritsiwo amayimitsidwa masiku 30 tsiku loyembekezereka lisanachitike ndipo ngati kuli kotheka, amasinthana ndi insulin. Pochita zithandizo zochizira, ndikofunikira kusiya kuyamwitsa.
The ntchito aimpso kuwonongeka
Dongosolo la hypoglycemic limatha kuchitika ndi vuto laimpso komanso kulephera kwa aimpso mukamamwa Minidiab.
Gwiritsani ntchito ntchito yolakwika ya chiwindi
Odwala omwe ali ndi vuto la chiwindi komanso osagwira bwino ntchito kwa chiwindi amathandizidwa moyang'aniridwa ndi katswiri wazachipatala.
Mankhwala ochulukirapo a Minidiab
Ngati mumagwiritsa ntchito mankhwalawa kuchuluka kwa mankhwalawa, mankhwala osokoneza bongo amatha kuchitika, monga umboni wa hypoglycemia.
Kuti muchotse zizindikiro zosasangalatsa, ndikofunikira kusiya kumwa mankhwalawa, kusintha zakudya ndi kudya shuga.
Ngati chiwonetsero choopsa cha hypoglycemia chikhala chofunikira kuchipatala, ndikuwapatsa njira ya 50% ya shuga m'mitsempha yake komanso munthawi yomweyo kukhetsa 10% shuga. Wodwala akatuluka chikomokere, amafunika kuwunika shuga wake wamagazi pafupipafupi. Kugwiritsa ntchito dialysis pankhaniyi sikungathandize.
Kugwiritsa ntchito dialysis ngati bongo ndi Minidiab sikungathandize.
Kuchita ndi mankhwala ena
Kutsika kwa ntchito yogwira ntchito kumawonedwa mukamayanjana ndi ma anticonvulsants, Baclofen, carbonic anhydrase inhibitors, amphetamines, glucocorticoids, calcium antagonists, mahomoni a chithokomiro, njira zakulera pakamwa, Epinephrine, Furosemide, ethacrine acid ndi mankhwala ena omwe angayambitse matenda oopsa.
Ntchito ya Hypoglycemic imalimbikitsidwa pamene mukutenga androgens ndi anabolic steroids. Kupititsa patsogolo kwa biotransfform komanso kuwonjezeka kwa kuchuluka kwa magazi m'thupi kumachitika pakaphatikizidwa ndi anticoagulants, NSAIDs, clofibrate, MAO inhibitors, sulfonamides, chloramphenicol, guanethidine, probenecid ndi rifampicin.
Kuwonjezeka kwa chikhalidwe cha hypoglycemic ndikutseka kwa inactivation kumawonedwa mutatenga Miconazole, Ketoconazole ndi Sulfinpyrazone. Chiwopsezo cha agranulocytosis chimawonjezeka ndi kuphatikiza kwa Minidiab ndi mankhwala a myelotoxic ndi antithyroid.
Kuyenderana ndi mowa
Kumwa mowa panthawi yamankhwala kungayambitse matenda ngati a disulfiram, omwe amachititsa kupweteka kwam'mimba, nseru, kusanza, ndi mutu.
Analogi
Ngati ndi kotheka, mankhwalawa amaloĊµedwa ndi mankhwala ofanana:
- Antidiab;
- Glibenesis;
- Glenezom;
- Glucotrol ChL.
Dokotalayo amasankha analogi yolingalira za wodwalayo komanso kuopsa kwa matendawo.
Kupita kwina mankhwala
Chipangizocho chitha kugulidwa ku pharmacy iliyonse ngati pali mankhwala kuchokera kwa dokotala.
Kodi ndingagule popanda kulandira mankhwala?
Mankhwala amaperekedwa pokhapokha ngati amupatsa mankhwala.
Mtengo wa Minidiab
Mtengo wa mankhwalawa umadalira mitengo yamapulogalamu ndi ma 2750 oyendetsa.
Zosungidwa zamankhwala
Phukusi lokhala ndi mapiritsi limayikidwa m'malo amdima, owuma komanso osafikira ana omwe ali ndi kutentha kosaposa + 25 ° C.
Tsiku lotha ntchito
Mankhwalawa amasunga katundu wawo kwa zaka 5 kuyambira tsiku lopangidwa, ngati malamulo osungira atsatiridwa. Tsiku lotha litatha, mankhwalawo amatayidwa.
Minidiab, yemwe ali ndi dzina loti mayiko osavomerezeka, Glipizide, amasungidwa m'malo amdima, owuma komanso osatheka ndi ana.
Wopanga
Kupanga mankhwalawa kumachitidwa ndi Pharmacia & Upjohn (Italy).
Ndemanga za Minidiab
Inna, wazaka 33, Stavropol: "Ndakhala ndikudwala matenda ashuga kwa zaka 6. Mankhwalawa amathandiza ndipo samayambitsa zotsatila, ngakhale kuti mankhwala ena anakhudza thanzi langa. Mtengo wake ndi wokwera, koma zotsatira zake zimatha kumveka pambuyo pa tsiku loyamba la chithandizo."
A Angelina, azaka 46, ku Moscow: "Mankhwalawa adalembedwa ndi adotolo. Ndidamwa mapiritsiwo malinga ndi dongosolo, koma patapita masiku angapo ndidayamba kusanza ndi kusanza. Mankhwalawa adayima ndipo tsopano ndikupimidwa kuti ndipeze yankho labwino."
