Mankhwala othandizira antibiotic amakonda kwambiri madokotala komanso odwala. Koma mndandanda uwu wa mankhwalawa umafunikira chisamaliro chapadera popereka mankhwala. Komanso, maantibayotiki sangathe kuperekedwera okha, chifukwa momwe amawagwirira ntchito nthawi zambiri amakhala osiyana. Pali mankhwala omwe ali ndi chophatikizira chimodzi, koma ndi zina zowonjezera. Ndalamazi ndi monga, mwachitsanzo, Flemoxin ndi Amoxicillin.
Makhalidwe a Flemoxin
Flemoxin, wogulitsidwa ku malo ogulitsa mankhwala omwe amagulitsidwa ndi dzina la malonda Flemoxin Solutab, ndi antibacterial mankhwala omwe amapezeka piritsi la 125, 250, 500 ndi 1000 mg, lomwe mkati mwake mumakhala gawo la penicillin mfululizo amoxicillin trihydrate ndi zina zowonjezera:
- cellulose wopezeka ndi MCC;
- crospovidone;
- magnesium wakuba;
- vanillin ndi saccharin;
- Zosefera zipatso.
Flemoxin Solutab ndi antibacterial mankhwala omwe amapezeka mu mawonekedwe a piritsi ku 125, 250, 500 ndi 1000 mg.
Flemoxin amagwira ntchito bwino pakuwonongeka kwa mabakiteriya okhala ndi gramu komanso gram-negative, koma ali ndi vuto pa staphylococcus ndi protein. Mankhwala othana ndi mankhwalawa sagwira ntchito kwa meningitis, popeza njira yolowera kulowa m'magazi a cerebrospinal ndi yayitali kwambiri.
Kamodzinso m'mankhwala, mankhwalawo amatengedwa mwachangu ndikulowa m'magazi. Kupanga metabolites yogwira, maantibayotiki amawononga chipolopolo cha mabakiteriya oyipa ndikuwononga matenda. Zolemba zake zapamwamba zimawonedwa patatha ola limodzi, zotulutsa zimaperekedwa ndi impso.
Njira yamaphunziridweyi malinga ndi njira yakaleyo imawonetsedwa katatu patsiku, mphindi 20-30 musanadye (kapena kuchuluka komweko), kwa masiku 5 (nthawi zina motalikirapo, koma kumbukirani kuti kugwiritsa ntchito maantibayotiki kwa nthawi yayitali kumawonjezera ndikusokoneza mphamvu yake chithandizo).
Flemoxin amaloledwa:
- ana (waukulu Mlingo);
- pa mimba;
- ndi mkaka oyamwa (mosamala).
Khalidwe la Amoxicillin
Chida chimenecho ndi cha mankhwala osokoneza bongo a gulu la penicillin, omwe amatengedwa kuti ndi otetezeka kwambiri pamankhwala onse omwe alipo a antibacterial. Mankhwalawa ndiwotchuka kwambiri pakati pa akatswiri, kuphatikiza ana.
Amoxicillin ndi imodzi mwa mankhwala omwe amapanga penicillin, omwe amati ndi otetezeka.
Mitundu ya mankhwala:
- mapiritsi a 250, 500 ndi 1000 mg;
- magalamu oimitsidwa - 250 mg / 5 ml;
- ma ampoules okhala ndi 15% r-r ogwiritsidwa ntchito ngati mankhwala azoweta.
Kuphatikizidwa kwa mitundu yolimba ya antibayotiki kumaphatikizanso zina zosakaniza:
- polysorbate (pakati 80);
- magnesium wakuba;
- wowuma;
- talcum ufa.
Kuyeserera kwa mankhwalawa kumachitika mwachangu, koma kulowa mu mucosa wam'mimba komanso osakhudza acidity mwanjira iliyonse. Ngati chakudya chosasankhidwa chimakhalabe m'mimba, ndiye kuti izi sizikhudza digestibility. Kuchuluka kwa mankhwala mu mtsinje wamagazi kumakhazikika pambuyo pa maola awiri, pomwe 20% imagawidwa limodzi ndi mapuloteni a plasma, mawonekedwe ena onsewo amalowa m'thupi lonse. Amoxicillin akuwonetsedwa pazambiri zotupa zomwe zimayambitsidwa ndi tizilombo tating'onoting'ono.
Lemberani mapiritsi (patsiku):
- achikulire ndi ana ochokera zaka 9 - 500 mg katatu;
- mu matenda pachimake - mpaka 1000 mg katatu;
- odwala osakwana zaka 8 - 250 mg katatu.
Kutalika kwa mankhwala ndi Amoxicillin kuli pafupifupi masiku 5-7.
Kutalika kwa mankhwala pafupifupi masiku 5-7. Koma kuikidwa kwa maantibayotiki ndikotheka kwa Amoxicillin okha omwe ali m'magulu oyambitsa matenda a penicillin, omwe amawaganizira kuti ndi otetezeka kwambiri. Malangizo a adotolo, popeza pali malangizo apadera a matenda osiyanasiyana:
- otitis ana - osachepera mlingo akuwonetsedwa 2, masiku 5;
- leptospirosis (kwa achikulire) - 0,5 g 4-4, mpaka masiku 12;
- ndi salmonellosis - 1 g katatu, masiku 15-30;
- odwala aimpso kukanika - pazipita tsiku lililonse 2 g;
- kupewa endocarditis pa opaleshoni - 4 g ola limodzi isanachitike.
Kuyerekeza kwa Flemoxin ndi Amoxicillin
Amoxicillin ndiye wotsogola wa mankhwala ambiri amakono. Mankhwala akhala pamsika kwa zaka zopitilira 50, panthawiyi makampani ambiri azamankhwala akhazikitsa njira yake:
- Bayer - Germany;
- World Pharmaceutical - USA;
- Katundu wa Natur - Netherlands;
- Serena Pharma - India;
- Hemofarm - Yugoslavia;
- Zachilengedwe, Biochemist, Bryntsalov-A, Vertex, Pharmasynthesis ndi ena. - Russia.
Iyenso ali ndi zophophonya zingapo, zomwe zidakonzedwa ndikubwera kwa generic Flemoxin Solutab, yomwe yakhala ikupangidwa ndi Astellas Pharma Corporation (Netherlands) kuyambira 2005.
Kufanana
Kuchita kwa maantibayotiki kumatengera mphamvu yomwe amagwiritsa ntchito - amoxicillin trihydrate. Mankhwala onse awiriwa amachokera ku nyimbo za gulu la penicillin, zomwe zimakhudza zomera za pathogenic momwemonso - kuwononga mabakiteriya polowetsa nembanemba. Zisonyezero zogwiritsidwa ntchito pachikuto cha matenda opatsirana:
- leptospirosis;
- endocarditis;
- sinusitis
- bronchitis;
- pharyngitis;
- tonsillitis;
- atitis media;
- chibayo
- matenda a impso ndi kwamikodzo thirakiti;
- kutupa mu matenda a m'mimba;
- matenda a pakhungu (dermatosis, erysipelas);
- zilonda zam'mimba.
Zoyipa:
- penicillin tsankho;
- lymphocytic leukemia;
- mphumu
- mitengo;
- matenda oopsa a impso.
Zotsatira zoyipa zomwe zimachitika ndi hypersensitivity ndi bongo:
- kuchepa magazi
- candidiasis;
- thrombocytopenia;
- yade;
- stomatitis
- kugona ndi kugona;
- chisokonezo cha chikumbumtima;
- leukopenia;
- mawonetseredwe a thupi lawo (kuphatikizapo edema ya Quincke);
- m'mimba kukhumudwa;
- kukokana.
Kodi pali kusiyana kotani?
Kusiyanitsa kwakukulu pakati pa mankhwalawa ndikuti Flemoxin amapangidwa mwa mawonekedwe osungunuka kwambiri komanso nthawi yomweyo pamafuta acid. Gawo lomwe limagwira, kulowa m'mimba, silikuwonongeka mothandizidwa ndi hydrochloric acid, koma limadutsa m'matumbo, pomwe limayamwa magazi oposa 90%. Izi zimathandiza kuti maantibayotiki alowe mwakuya kwambiri pamatenda oyenera omwe ali ndi mitundu ya mankhwala.
Amoxicillin ali ndi mawonekedwe osiyanasiyana, motero amayamba kuthyoka ngakhale m'mimba, chifukwa chake samakamizidwa kwathunthu. Koma mankhwala akale ndi omwe amayesedwa nthawi yayitali amatha bwino ndi kutupa kwa microflora ya m'mimba. Kugwirizana kwamankhwala sikugwiritsidwa ntchito (pambuyo pa zonse, ndi chinthu chimodzi), magawo awiri apitilira muyeso, omwe ndiowopsa poyankha mosiyanasiyana. Ndipo amaloledwa kulowetsa ndalamazo panthawi yamankhwala.
Chojambula chosasinthika chinganenedwenso kuti Amoxicillin ndiwowawa.
Flemoxin akuwonekeranso poyerekeza ndi ma analogue munjira yapadera yopezeka. Ubwino wake:
- odzipereka mwachangu m'mimba;
- ali ndi bioavailability wamkulu;
- chifukwa cha nembanemba yapadera, imalowetsedwa m'magazi, kudutsa m'mimba;
- M'malo mwake mumakhala ndende yayikulu kwambiri.
Chojambula chosasinthika chinganenedwenso kuti Amoxicillin ndiwowawa. Flemoxin ali ndi fungo labwino komanso kununkhira bwino.
Zomwe zili bwino
Flemoxin ndi mankhwala apamwamba kwambiri. Monga mankhwala othandizira, imakhala ndi cellulose, yomwe imagwiritsa ntchito bwino kusungunuka, komanso madzi ochepa kwambiri. Flemoxin nthawi zambiri imaloledwa kugwiritsidwa ntchito panthawi yapakati. Zomwe zakhala zikuchitika kwa nthawi yayitali popereka mankhwalawa zimapatsa ufulu kulingalira mankhwalawa ngati mankhwala otetezedwa omwe amavomerezeka kwa ana ndi amayi apakati. Komabe, mawonekedwe othandizira a Flemoxin ali ndi saccharin, zomwe zikutanthauza kuti ndibwino kuti odwala omwe ali ndi matenda ashuga apereke mawonekedwe akale.
Zomwe zimakhala zotsika mtengo
Mtengo Wa Amoxicillin:
- Mapiritsi a 250 mg No. 20 - 26.10 ma ruble.; 500 mg No. 20 - 56.50 rubles.; 1000 mg No. 12 - ma ruble 140;
- ma granles d / susp. 100 ml (250 mg / 5 ml) - ma ruble 76.50.
Flemoxin nthawi zambiri imaloledwa kugwiritsidwa ntchito panthawi yapakati.
Mtengo wa mapiritsi Flemoxin Solutab No. 20:
- 125 mg - 194.50 rub .;
- 250 mg - 238.50 rubles;
- 500 mg - 312 ma ruble;
- 1000 mg - 415.50 rub.
Poyerekeza mitengo, zikuwonekeratu kuti ndizopindulitsa kwambiri kugula Amoxicillin.
Zomwe zili bwino - Flemoxin kapena Amoticillin
Akatswiri akukhulupirira kuti zomwe zachitika posachedwa zamankhwala zothandiza kukonza katundu, kuonetsetsa chitetezo, kukonza magawo ena, zimapangitsa Flemoxin kukhala chisankho chabwino kwambiri. Otsitsawo, kuchotsa zolakwa za Amoxicillin, adasiya zabwino zawo. The bioavailability wa generic mankhwala yawonjezeka, ndipo zotsatirapo zake zachepa. Koma kuti mudziwe njira yanji yomwe imagwira ntchito bwino, dokotala ayenera kutengera izi:
- matenda apano;
- kuopsa kwa vutolo;
- zaka odwala;
- Zizindikiro zololera gawo.
Kwa mwana
Ngakhale mankhwalawa onse amatha kugwiritsidwa ntchito ngati ana, Flemoxin amawonetsedwa pafupipafupi, popeza:
- mitundu yake yamapiritsi imakhala ndi mlingo wotsika kuposa amoxicillin;
- Mapiritsi a ana a 125 mg ndi osavuta kupasuka m'madzi;
- zitha kugwiritsidwa ntchito ngakhale kwa akhanda;
- amatha kusungunuka mkaka wa m'mawere.
Kuti mwana akhale wofunitsitsa kumwa mankhwalawo, ndikofunikira kuganizira kukoma kwake. Apa Flemoxin apambananso, chifukwa alibe kuwawa komwe amapezeka m'mapiritsi ambiri. Otsatsa a Astellas Pharma adalowa m'malo mwa kukoma kwa Amoxicillin ndi saccharin ndi othandizira anzawo.
Madokotala amafufuza
S.K. Sotnikova, wothandizira, Moscow
Muyenera kugula kokha mlingo woyenera. Kugawana mankhwalawa sikulimbikitsidwa. Mutha kuwona kuti mapiritsi ambiri ali pachiwopsezo. Izi sizitanthauza kuti wamkulu mlingo akhoza kugawidwa ana. Kugawikaku sikunachitike kuti muchepetse kuchuluka kwa mankhwalawa 2 kawiri kakang'ono - chipolopolo chakunja chimateteza piritsi pazowonongeka.
G.N. Sakhala, dokotala wa ana, Novgorod
Ndi atitis media, ndalama zonsezi zitha kuperekedwa kwa ana mosamala. Zotsatira zoyipa ndizochepa. Ndikupangira kutenga mpaka zizindikiro zazikuluzo zikazimiririka komanso masiku angapo.
T.M. Tsarev, gastroenterologist, Ufa
Amoxicillin ndi mankhwala otchuka kwambiri padziko lonse lapansi, opangidwa ndi akatswiri azachipatala mu 60s omalizira ku Britain. Ndipo Flemoxin ndi generic wake wopambana. Koma matupi osokoneza bongo a urticaria adakumana nawo (ndi mankhwala osokoneza bongo).
Ndemanga za Odwala za Flemoxin ndi Amoxicillin
Maria, wazaka 33, Tula
Chithandizo chabwino kwambiri cha mankhwala ndi Amoxicillin. Sindimadziwa kuti pali analogue tastier. Mitengo ndi yokwera, koma kwa mwana ndimusankha.
Tatyana wazaka 45, Kimry
Mlingo ndi mitundu yothandizira ma antibayotiki ndimunthu payekha, kutengera zomwe muyenera kuchita. Ngati ndizotheka kwa odwala omwe ali ndi zilonda zam'mimba, ndiye kuti mavuto omwe ali ndi mabakiteriya a ndulu sangathe (monga adokotala adanena). Osadzisilira.
Katya, wazaka 53, Ukhta
Flemoxin adalandira mankhwala ochizira chifuwa chosatha. Ndizabwino kuti zimanunkhira ngati lalanje, koma popeza njira zake zimakhala zofanana, ndimakonda Amoxicillin wotsika mtengo komanso wowonjezereka.
