Mankhwala Kefsepim: malangizo ntchito

Kefsepim adapangira zochizira matenda oyambitsidwa ndi matenda. Amagwiritsidwa ntchito ngati mtsempha wa intravenous komanso intramuscular.

Dzinalo Losayenerana

Cefepime.

Kefsepim adapangira zochizira matenda oyambitsidwa ndi matenda.

ATX

J01DE01.

Kutulutsa mafomu ndi kapangidwe kake

Amatulutsidwa ngati ufa kuti athe kupeza yankho la kulowetsedwa kwa mtsempha wamkati ndi mu mnofu. Chosakaniza chophatikizacho ndi cefepime (500 kapena 1000 mg mu botolo limodzi).

Zotsatira za pharmacological

Izi ndi antibacterial wothandizila kuchokera pagulu la cephalosporins. Ili ndi ntchito zambiri pofotokoza mitundu ingapo yama virus omwe amalimbana ndi mankhwala wamba a antibacterial. Kanani kuzichotsa ndi beta-lactamases. Amalowa mosavuta m'maselo a bakiteriya.

Imagwira motsutsana ndi anaerobes, tizilombo ta Streptococcus pyogene, enterobacteria, Escherichia, Klebsiella, Proteus mirabilis, pseudomonas.

Zosiyanasiyana zamtundu wamtundu wa enterococci, staphylococci kugonjetsedwa ndi methicillin, clostridia sazindikira maantiotic.

Pharmacokinetics

Kuphatikizika kwakukulu kwa mankhwala othandizira mu plasma kumatheka pambuyo pa theka la ora ndipo kumatha kwa maola 12. Kutha kwa theka-moyo kumachitika kuyambira maola 3 mpaka 9.

Amapezeka mumkodzo, bile, bronchial secretion, Prostate.

Kefsepim amagwiritsidwa ntchito pochiza matenda a m'mimba oyambitsidwa ndi bakiteriya.

Kefsepim amagwiritsidwa ntchito pochiza pyelonephritis.

Kefsepim akuwonetsedwa kuti azikhala ndi chibayo champhamvu kwambiri.

Mankhwalawa amagwiritsidwa ntchito pochiza matenda amkodzo oyambitsidwa ndi mabakiteriya.

Zizindikiro zogwiritsidwa ntchito

Amawonetsedwa muzochitika zotere:

1. Mtundu wapakati komanso wowopsa wa chibayo chomwe chimayambitsidwa ndi mavuto a Streptococcus streptococcus pneumoniae, Pseudomonas aeruginosa, Klebsiella kapena mitundu yosiyanasiyana ya enterobacteria.
2. Febrile neutropenia (monga mankhwala othandizira).
3. Matenda a urinary thirakiti (yamitundu yosiyanasiyana yovuta) yoyambitsidwa ndi bakiteriya Staphylococcus aureus ndi Streptococcus pyogene.
4. Pyelonephritis.
5. Zovuta zam'mimba zam'mimba zomwe zimayambitsidwa ndi mabakiteriya - Escherichia, Klebsiella, pseudomonads makamaka Enterobacter spp.
6. Kupewa matenda osiyanasiyana opaleshoni yam'mimba.

Contraindication

Mankhwalawa adapangidwa mu:

1. Hypersensitivity thupi kupita ku cefazolin, mankhwala a cephalosporin, kukonzekera kwa penicillin, mankhwala a beta-lactam, L-arginine.
2. Zaka za mwana zafika mpaka miyezi iwiri (ngati ndi kotheka, makonzedwe a mtsempha). Kuthekera kwa kuyambitsa Kefsepim m'gulu ili la odwala sikunaphunzire.

Sizoletsedwa kuchita jakisoni wamkati mpaka zaka 12.

Ndi chisamaliro

Mosamala kwa anthu omwe apeza matenda am'mimba, chizolowezi chomwa mankhwala. Ngati pali chifuwa, mankhwalawo amachotsedwa.

Kefsepim amaperekedwa kudzera m'mitsempha monga kulowetsedwa.

Ndi koletsedwa kupanga jakisoni wa mu mnofu kwa ana osakwana zaka 12.

Kefsepim iyenera kudulidwa limodzi ndi lidocaine hydrochloride.

Momwe mungatenge Kefsepim

Imaperekedwa kudzera m'mitsempha monga kulowetsedwa. Kutalika kwa njirayi sikuchepera theka la ola. Mothandizidwa ndi makulidwe a mankhwalawa amaloledwa kulowetsedwa kapena kwamtundu wa kwamikodzo thirakiti. Mlingo umatengera mtundu wa tizilombo toyambitsa matenda, kuopsa kwa matenda opatsirana komanso ntchito ya impso.

Mankhwala ayenera kubayidwa limodzi ndi lidocaine hydrochloride.

Pneumonia: 1-2 g yankho limalowetsedwa m'mitsempha kawiri pa tsiku ndi pafupipafupi kwa maola 12. Kutalika kwa chithandizo ndi masiku 10.

Ngati kwamikodzo thirakiti matenda: jekeseni mu mtsempha kapena kholo pa 500-1000 mg pambuyo maola 12 kwa masiku 7-10.

Ngati matenda apakhungu pakhungu ndi minofu yofewa: 2 g ya mankhwala amalowetsedwa m'mitsempha ndi pafupipafupi kwa maola 12. Nthawi ya chithandizo ndi masiku 10. Mlingo womwewo ndi nthawi ya kutumikiridwa kwa mankhwalawa amagwiritsidwa ntchito pamatenda am'mimba.

Popewa matenda pakachitika opaleshoni yam'mimba, iv imayikidwa ola limodzi lisanachitike. Kuchuluka kwa mankhwalawa ndi 2 g. Yankho limaletsedwa kugwiritsidwa ntchito nthawi imodzi ndi metronidazole. Ngati pakufunika kuyambitsa metronidazole, ndiye kuti muyenera kutenga syringe ina kapena kulowetsedwa.

Kwa ana, mlingo umasankhidwa malinga ndi kuchuluka kwa 50 mg pa kilogalamu ya thupi. Pafupipafupi jakisoni ndi maola 12, ndipo kuchepa kwa chiwerengero cha neutrophils - maora 8.

Kulephera kwa aimpso, kuchuluka kwa mankhwalawa kumachepa.

Kulephera kwa aimpso, kuchuluka kwa mankhwalawa kumachepa.

Odwala ena, akatha kugwiritsa ntchito mankhwalawa, khosi limawoneka.

Kefsepim angayambitse vuto la kusokonezeka kwa chidwi.

Pambuyo kugwiritsa ntchito mankhwalawa, systemic lupus erythematosus imatha kuoneka.

Kumwa mankhwalawa kumatha limodzi ndi rheumatism.

Mukamagwiritsa ntchito mankhwalawa, mutha kukumana ndi mawonekedwe oyipa ngati kupweteka kumbuyo.

Mankhwalawa angayambitse kusintha kwa magawo a magazi a labotale.

Ndi matenda ashuga

Kuwonjezeka kwa shuga sichizindikiro chochepetsa.

Zotsatira zoyipa za Kefsepim

Zitha kuyambitsa mavuto osiyanasiyana, makamaka kwa odwala omwe akhudzidwa ndi maantibayotiki.

Odwala ena amakhala ndi zilonda zapakhosi, kumbuyo, malo opaka jakisoni, malingaliro olakwika a m'maso, komanso kufooka kwambiri. Ndi jakisoni wa iv, phlebitis imayamba. Chifukwa cha kayendetsedwe ka i / m, kupweteka kwambiri kumawonekera. Pafupipafupi ndiye kukula kwa chikhulupiriro champhamvu.

Kuchokera minofu ndi mafupa

Pafupipafupi: mawonekedwe a systemic lupus erythematosus, rheumatism, kutupa kwa mafupa.

Matumbo

Matenda am'mimba am'mimba amatha, amawonetsedwa ndi mseru, kusanza, kudzimbidwa kapena kutsegula m'mimba. Nthawi zambiri odwala amakhudzidwa ndi ululu wam'mimba.

Zizindikiro za Dyspeptic zimachotsedwa mosavuta mothandizidwa ndi ma proiotic.

Hematopoietic ziwalo

Mankhwala angayambitse kusintha kwa magawo a magazi a labotale ndi vasodilation.

Pakati mantha dongosolo

Zotupa za CNS:

• kupweteka pamutu;
• chizungulire chachikulu;
• kusokonezeka kwa tulo mu mawonekedwe a kusowa tulo usiku ndi kugona tulo masana;
• zovuta zamaganizidwe;
• kumverera kwa nkhawa kwambiri;
• chisokonezo chachikulu;
• chidwi, kukumbukira ndi kusamalira;
• minofu yolimba.

Mukatha kugwiritsa ntchito mankhwalawa, mutu umagwa nthawi zambiri, womwe ndi chizindikiro cha zotsatira zoyipa.

Kugwiritsa ntchito mankhwalawa kumatha kukhala limodzi ndi chizungulire chachikulu.

Mankhwalawa angayambitse kusokonezeka kwa kugona mu mawonekedwe a kugona tulo usiku.

Poyerekeza ndi kugwiritsa ntchito mankhwalawa, kusemphana ndi mseru kumachitika.

Pogwiritsa ntchito mankhwalawa, zimachitika zovuta monga kudzimbidwa kapena kutsegula m'mimba.

Nthawi zambiri pambuyo pakugwiritsidwa ntchito ndi Kefsepim, odwala amakhudzidwa ndi kupweteka kwam'mimba.

Kefsepim ikhoza kuyambitsa kukumbukira.

Ndi chithandizo chazitali kwa odwala omwe ali ndi matenda a impso, kuwonongeka kwambiri kwa ubongo ndikotheka.

Kuchokera kwamikodzo

Nthawi zina zimabweretsa zowonongeka zazikulu mu dongosolo la ma excretory. Amatha kudziwonetsa kuchepa kwamkodzo (mpaka anuria).

Kuchokera ku kupuma

Kuwonongeka kwa kupuma kwamphamvu kumatha. Odwala amakhudzidwa ndi kutsokomola, kumverera kwachifuwa komanso kupuma movutikira.

Kuchokera ku genitourinary system

Azimayi amatha kusokonezedwa ndi kumaliseche ndi kuyamwa mu perineum.

Kuchokera pamtima

Mwina chitukuko cha tachycardia, edema.

Matupi omaliza

Thupi lawo siligwirizana limawonekera mu:

• zotupa, makamaka erythema;
• malungo;
• anaphylactoid zochitika;
• eosinophilia;
• erythema multiforme exudative;
• Steven Johnson matenda.

Thupi lawo siligwirizana ndi mankhwalawa limadziwoneka ngati totupa.

Mankhwala amatha kuyambitsa tachycardia.

Mukatha kugwiritsa ntchito Kefsepim, azimayi amatha kusokonezeka chifukwa cha kutuluka kwamkati ndi kuyabwa mu perineum.

Mukumwa mankhwalawa, kutsokomola kumachitika.

Madokotala amalimbikitsa kuti musayendetse galimoto panthawi yomwe Kefsepim amathandizira.

Wodwala akayamba pseudomembranous colitis, ndiye kuti Kefsepim amayima.

Mukatha kugwiritsa ntchito mankhwalawa, wodwalayo amatha kusokonezedwa ndi kupuma movutikira.

Zokhudza mphamvu pakuwongolera njira

Nthawi zina, mankhwalawa angayambitse kusokonezeka kwa chikumbumtima, kuchepa ndende. Chifukwa chake, madotolo amalimbikitsa kuti musayendetse galimoto ndipo musamagwire ntchito ndi zovuta pakugwirira ntchito.

Malangizo apadera

Wodwala akayamba matenda a pseudomembranous kapena anti-anti-colitis, kutsekula m'mimba nthawi yayitali, ndiye kuti mankhwalawa amasiya. Vancomycin kapena metronidazole amatumizidwa pakamwa.

Gwiritsani ntchito mu ukalamba

Ndi kuvulala kwambiri kwa aimpso, kuchepetsa mlingo kapena kubwezeretsa mankhwala ndikofunikira.

Kupatsa ana

Osasankhidwa kwa ana osakwana miyezi iwiri.

Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere

Gwiritsani ntchito nthawi ya phwando pokhapokha ngati mphamvu yomwe mwapeza ikukweza kuposa momwe mungathere. Mu trimester yoyamba sakusankhidwa.

Kefsepim imagwiritsidwa ntchito pa nthawi ya pakati pomwe kufunika komwe kumakhala kukuchulukitsa ngozi zomwe zingatheke.

Pa mankhwalawa ndi Kefsepim pa mkaka wa m`mawere, mwanayo amasinthidwa kuti adyetsedwe.

Matenda akulu a chiwindi - chizindikiro chochepetsera mlingo wa Kefsepim.

Kefsepim salembera ana osakwana miyezi iwiri.

Ngati kuli kofunika kuchita chithandizo mukamayamwitsa, ndiye kuti mwanayo ayenera kusinthidwa kwakanthawi kuti ayambe kudya zakudya zosafunikira.

The ntchito aimpso kuwonongeka

Ndi aimpso a impso, kuchepetsedwa kwa mlingo kumafunika poganizira kuchuluka kwa creatinine. Ndikofunikira kuwunika nthawi zonse zomwe zimapezeka m'magazi.

Gwiritsani ntchito ntchito yolakwika ya chiwindi

Matenda akulu a chiwindi - chisonyezo chochepetsera mlingo kapena kusintha mankhwalawo ngati mawu atasintha mu chithunzi cha magazi.

Kefsepim bongo

Ngati chiwopsezo chikuwonjezeka, wodwalayo amatha kukumana, kuwonongeka kwa ubongo, mantha komanso minyewa. Nthawi zambiri, zizindikirozi zimawonekera mwa anthu omwe ali ndi matenda ovuta a impso.

Chithandizo cha mankhwala osokoneza bongo odwala chithupsa mpaka hemodialysis njira ndi symptomatic kukonza mankhwala. Kukula kwa kusintha kwak pachimake kwachilendo kwazizindikiro ndi chidziwitso chokhazikitsidwa ndi adrenaline.

Kuchita ndi mankhwala ena

Mankhwalawa saphatikizana ndi heparin analogues, maantibayotiki ena.

Ma diuretics amachulukitsa kuchuluka kwa mankhwala m'magazi ndipo amatha kupweteka kwa impso. Kumwa mankhwala osagwiritsa ntchito mankhwala a anti-yotupa kumawonjezera mwayi wokhetsa magazi kwambiri.

Kefsipim saloledwa kuti agwiritsidwe ntchito molumikizana ndi mankhwala osapweteka a antiidal.

Njira yothetsera vutoli sayenera kuperekedwa mu syringe yomweyo ndi mankhwalawa:

• Vancomycin;
• Gentamicin;
• Tobramycin;
• Netilmicin.

Maantibayotiki onse operekedwa ndi Kefsepim ayenera kuperekedwa padera.

Kuyenderana ndi mowa

Zosagwirizana ndi mowa.

Analogi

Monga mankhwala othandizira:

• Abipim;
• Agicef;
• Kusangalatsa;
• Extentsef;
• Maxinort;
• Maksipim;
• Septipim.

Kupita kwina mankhwala

Yoperekedwa ndi mankhwala.

Kodi ndingagule popanda kulandira mankhwala?

Mankhwala sangatheke popanda kulandira mankhwala.

Mtengo

Mtengo wa 1 g wa kapangidwe kake kuti mupeze yankho ndi pafupifupi ma ruble 170.

Zosungidwa zamankhwala

Musayandikire kuwala ndi chinyezi, kutali ndi ana.

Tsiku lotha ntchito

Ndiwothandiza kwa zaka 3 kuyambira tsiku lopangidwa.

Wopanga

Oxford Laboratories Pvt. Ltd, India.

M'malo mwa mankhwalawa atha kukhala Abipim.

Omwe alinso ndi makina ofananawo ndi monga Maksipim.

M'malo mwake mankhwalawo ndi mankhwala monga Extentsef.

Ndemanga

Irina, wazaka 35, ku Moscow: "Mothandizidwa ndi Kefsepim, ndidachiritsa chibayo cham'mimba. Mankhwalawa adachitika kuchipatala kwa masiku 10. Ndinalekerera jakisoniyo, ngakhale anali ndi ululu."

Olga, wazaka 40, Ob: "Mankhwalawa adathandizira kuchiritsa kwamkodzo kwamkodzo, komwe kumayendera limodzi ndi kupweteka pakukodza. Mankhwalawa amathandizidwa bwino, sizinadzetse zotsatirapo zake.

Oleg, wazaka 32, St. Petersburg: Mankhwala abwino omwe adathandiza kuthana ndi kutupa kwa bronchi. Chifukwa cha matenda a bronchitis osachiritsika, ndinali ndi chifuwa chachikulu, chomwe chimachoka nditangoponya Kefsepim. "