Rosinsulin ndi mankhwala aku Russia omwe amagwiritsidwa ntchito pokonzanso chithandizo cha anthu omwe amadalira insulin omwe ali ndi matenda a shuga. Kusiyana kwakukulu pakati pamafomu ake omasulidwa ndi nthawi yogwira ntchito yogwira ntchito.
Dzinalo Losayenerana
Mu Russia - Human genetic Engineering Insulin. Mu Chilatini - Rosinsuline.
Rosinsulin ndi mankhwala aku Russia omwe amagwiritsidwa ntchito pokonzanso chithandizo cha anthu omwe amadalira insulin omwe ali ndi matenda a shuga.
ATX
A10AC01
Kutulutsa mafomu ndi kapangidwe kake
Mankhwalawa ali ndi mafomu atatu omasulidwa, omwe akuwonetsedwa ndi zilembo zingapo m'dzina:
- "P" - yankho lomwe lili ndi insulin;
- "C" ndi kuyimitsidwa komwe kuli ndi insulin isophan;
- "M" ndi osakaniza a mitundu yonse iwiri ya insulini pamlingo wa 30/70.
Iliyonse mwa mitunduyi yotulutsira ili ndi 1 ml ya 100 IU ya insulin. Madziwo amaikidwa m'mbale makilogalamu atatu kapena m'mbale 5 kapena 10 ml.
Zotsatira za pharmacological
Insulin imamangiriza ma cell wall receptors, imalimbikitsa kuyambitsa kwa intracellular enzyme synthesis process. Mphamvu ya glycoglycemic ya mankhwala chifukwa cha kuthekera kwake:
- kuwonjezera kuchuluka kwa shuga m'magazi ndikulimbikitsa kukonzekera kwake;
- kukulitsa machitidwe a lipogenesis ndi glycogenogeneis;
- ziletsa kupanga shuga ndi chiwindi.
Mankhwalawa ali ndi mitundu itatu yamasulidwe, yomwe imawonetsedwa ndi zilembo zingapo mdzina, imodzi mwazo ndi "P" - yankho lomwe lili ndi insulle ya insulin.
Pharmacokinetics
Mlingo ndi kuchuluka kwa mayamwidwe a mankhwalawa zimatengera tsamba la jakisoni ndi Mlingo. Mafuta osungunuka, omwe ndi gawo la Rosinsulin R, amayamba kugwira ntchito patatha mphindi 30, kutalika konse kwa njira zochizira ndi maola 8. Kuzindikira kwakukulu kumatheka patatha maola 1-3 pambuyo pa utsogoleri.
Zochita za isofan insulin zimayamba pambuyo pa maola 1.5, nthawi ya achire ikufika tsiku. Kukula kwakukulu kumawonedwa munthawi ya maola 4-12.
Mankhwala, omwe ndi osakanikirana a insulin yofulumira komanso yapakati, amayamba kugwira ntchito theka la ola pambuyo pa kupangika ndipo amakhala akugwira ntchito mpaka tsiku limodzi.
Mankhwalawa amadziwika ndi gawo losagwirizana mu minofu, samatha kulowa mkati mwa placenta ndikuyamwa mkaka wa m'mawere. Amapukusidwa ndi insulinase, yomwe imachotsedwa m'thupi ndi impso.
Zizindikiro zogwiritsidwa ntchito
Zisonyezero zakugwiritsa ntchito Rosinsulin ndi mtundu 1 wa matenda a shuga ndi mtundu 2 wa matenda a shuga pachimake cha kukanika kwathunthu kapena pang'ono kwa mankhwala a hypoglycemic omwe amapangidwa ndi mapiritsi, komanso matenda amodzi.
Kuphatikiza apo, yankho la Rosinsulin limalembedwa kwa odwala omwe ali ndi matenda a shuga a mtundu wachiwiri.
- matenda ashuga ketoacidosis;
- matenda a shuga;
- Pamaso pa opareshoni;
- matenda limodzi ndi kutentha thupi.
Mankhwalawa amathandizanso kuti matenda ashuga apatsidwe pakati. Amagwiritsidwa ntchito pofotokoza momwe chithandizo cha zakudya sichimapereka.
Contraindication
Sichikuperekedwa kwa hypersensitivity ku mtundu uwu wa insulin, komanso hypoglycemia.
Ndi chisamaliro
Kusankhidwa kwa Mlingo uyenera kuchitika mosamala pochiza odwala omwe:
- milandu ya cerebrovascular ngozi malinga ndi mtundu wa ischemic;
- Matenda akulu a mtima;
- ochepa stenosis;
- kuchuluka retinopathy.
Momwe mungatenge Rosinsulin
Jakisoni wogwiritsa ntchito zolembera, ndi kofunikira kutsatira malangizo a wopangidwawo. Ndikofunika kuti musachotsere singano isanakwane masekondi 6 atatha kuyimitsa ndikuti musatulutse batani la chogwiririra mpaka litachotsedwa kwathunthu. Izi zikuwonetsetsa kuyikiridwa molondola kwa mankhwalawo ndipo zitha kulepheretsa magazi kulowa mu yankho.
Mukamagwiritsa ntchito zolembera zokhazikikanso mutakhazikitsa cartridge, onetsetsani kuti mzere wachikuda uwonekera kudzera pazenera la wogwirizira.
Asanakhazikitsidwe kwa Rosinsulin C kapena Rosinsulin M, ndikofunikira kugwedeza mosamala mankhwalawa kuti mupeze kufanana kwathunthu kwa kuyimitsidwa.
Jakisoni wogwiritsa ntchito zolembera, ndi kofunikira kutsatira malangizo a wopangidwawo.
Ndi matenda ashuga
Kukula kwa mlingo kumatsimikiziridwa payekha kwa wodwala aliyense. Malinga ndi ziwerengero, avareji ya tsiku ndi tsiku ndi 0,5 - 1ME pa 1 kg ya odwala. Kusankha kuyenera kutengera ndi kuchuluka kwa shuga m'magazi. Miyeso iyenera kumwedwa musanadye komanso maola 1-2 mutatha kudya.
Jakisoni wa insulin amachitika mphindi 20 asanadye. Mankhwala omwe atumizidwa ayenera kukhala ndi kutentha kwa chipinda.
Jakisoni wa Rosinsulin P akhoza kuphatikizidwa ndi mankhwala omwe akhala akuchita kwa nthawi yayitali. Itha kuperekedwa kudzera m'mitsempha kapena m'mitsempha. Ndikofunikira kumadulira katatu patsiku, chifukwa amakhala ndi nthawi yochepa.
Mitundu yosiyanasiyana ya Rosinsulin "C" ndi "M" amaonetsa jakisoni wokhazikika kamodzi patsiku. Pamaso jakisoni, kukonzekera kophatikizidwa kuyenera kusakanikirana modekha mpaka yankho lake ndi lokha.
Zotsatira zoyipa za Rosinsulin
Pa mbali ya ziwalo zamasomphenya
Kumwa mankhwalawa kumatha kupangitsa kuchepa kwamawonedwe owoneka. Zotsatira zoyipa izi ndizosakhalitsa.
Dongosolo la Endocrine
Mwina chitukuko cha hypoglycemia, chodziwika ndi izi:
- womvera
- palpitations
- kugwedezeka
- zosokoneza tulo.
Kuphatikiza apo, kuwonjezereka kwa gawo la anti-insulin matupi komanso kusintha kwamphamvu kwa ma cell a insulin kumatheka.
Matupi omaliza
Thupi lawo siligwirizana ndi mankhwalawa lingachitike mwanjira ya:
- urticaria;
- malungo
- kupuma movutikira
- kuchepetsa kupsinjika;
- angioedema.
Zokhudza mphamvu pakuwongolera njira
Mankhwala pawokha samakhudza kuthekera kwakuya ndi kuyang'anira machitidwe. Hypoglycemia, yomwe imatha kuchitika pakumwa mankhwala ndi mankhwalawa, imapangitsa kuti munthu azitha kuwongolera machitidwe.
Mankhwala pawokha samakhudza kuthekera kwakuya ndi kuyang'anira machitidwe.
Malangizo apadera
Pa chithandizo cha insulin, tsamba la jakisoni liyenera kusinthidwa pafupipafupi kupewa lipodystrophy pamalo a jakisoni. Kuphatikiza apo, ngati mlingo umodzi woposa 0.6 IU / kg, kuchuluka kwa mankhwalawo kuyenera kugawidwa majakisoni awiri.
Zambiri zimatha kuyambitsa kukula kwa hypoglycemia, chifukwa chake, zikafika, kusintha kwa mankhwalawa ndikofunikira. Izi zikuphatikiza:
- kuchuluka zolimbitsa thupi;
- kudumpha chakudya;
- kusanza ndi kutsegula m'mimba;
- kusintha kwa mankhwala osokoneza bongo kapena malo oyang'anira;
- kuchepa kwa insulin chifukwa cha matenda a chithokomiro, chiwindi, impso, ndi zina zambiri.
- Kukhazikitsidwa kwa mankhwala ndi mankhwala ochepetsa insulin.
Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere
Mankhwala amavomerezedwa kuti azigwiritsidwa ntchito panthawi yoyembekezera komanso mkaka wa m'mawere. Pankhaniyi, ndikofunikira kusintha mlingo woganizira kusintha kwa thupi la mzimayi kumafunikira insulin nthawi yayitali. Mwachitsanzo, mu trimester yoyamba, ndikofunikira kuchepetsa kuchuluka kwa mankhwala omwe amaperekedwa. M'tsogolomu, mlingo uyenera kuwonjezeka pang'onopang'ono.
Mankhwalawa amavomerezedwa kuti azigwiritsidwa ntchito pa nthawi ya pakati.
Pa mkaka wa m`mawere, kuwunika tsiku lililonse misempha ya magazi kumafunika mpaka mlingo wofunikira ukhale wolimba.
Kupangira Rosinsulin kwa Ana
Kupereka mankhwala kwa ana ndikovomerezeka, koma kusankha kwa mankhwalawa kuyenera kuchitika moyang'aniridwa ndi achipatala.
Gwiritsani ntchito mu ukalamba
Pazaka 65, kusintha kwa mlingo kumafunika. Izi zimachitika chifukwa cha kusintha kwa thupi, makamaka kuwonongeka kwa impso, ndikutsatiridwa ndi insulini yochedwa.
The ntchito aimpso kuwonongeka
Kuwonongeka kwa impso kumachepetsa insulin, komwe kumayambitsa hypoglycemia. Chifukwa chake, kusankha kwa mankhwalawa kuyenera kuchitika mosamala.
Gwiritsani ntchito ntchito yolakwika ya chiwindi
Kusokonezeka kwa chiwindi kumabweretsa kutsika pakupanga shuga. Potengera momwe Rosinsulin imathandizira, izi zimatha kupangitsa kuti shuga achepetse thupi. Mwakutero, mlingo wa mankhwala omwe amalandiridwa ndi odwala omwe ali ndi matenda a chiwindi ayenera kuchepetsedwa.
Potengera momwe Rosinsulin imathandizira, izi zimatha kupangitsa kuti shuga achepetse thupi.
Mankhwala osokoneza bongo a Rosinsulin
Mankhwala osokoneza bongo a bongo amatsogolera pakukula kwa hypoglycemia. Analimbikitsa kudya zakudya zamafuta ambiri. Chifukwa chake, anthu omwe amagwiritsa ntchito insulin nthawi zonse amalangizidwa kuti azinyamula maswiti kapena msuzi wa zipatso kuti kuchepetsedwa kosavomerezeka kwa shuga m'magazi. Woopsa kwambiri, kuyamwa kwa njira ya shuga kungafunike.
Kuchita ndi mankhwala ena
Mphamvu ya Rosinsulin imalimbikitsidwa pamene itengedwa limodzi ndi mankhwala monga:
- MAO, ACE, phosphodiesterase ndi carbonic anhydrase inhibitors;
- beta-blockers omwe ali ndi zotsatira zosasankha;
- anabolics;
- tetracycline maantibayotiki ndi sulfonamides;
- othandizira antitumor;
- amphetamine zotumphukira zomwe zimagwiritsidwa ntchito kuti zikhazikitse kulakalaka;
- dopamine zolandilira;
- Octreotide;
- anthelmintic agents;
- pyridoxine;
- lipid-kuchepetsa mankhwala.
Mphamvu ya Rosinsulin imalimbikitsidwa pamene itengedwa limodzi ndi Octreotide.
Zinthu zingapo zimachepetsa mphamvu ya mankhwala a Rosinsulin. Zina mwa izo ndi:
- mahomoni a chithokomiro;
- diuretics of thiazide ndi loop kanthu;
- heparin;
- glucagon;
- estrogens, kuphatikiza zomwe zimapezeka mu njira zakulera zamlomo;
- antidepressants a gulu lachitatu;
- blockers of histamine receptors ndi pang'onopang'ono calcium njira;
- antiepileptic mankhwala a gulu la zotumphukira za hydatoin;
- analogual adrenaline.
Kuyenderana ndi mowa
Mankhwala a insulin amachepetsa thupi kukana mowa. Chifukwa chake, mowa umapangidwa mwa iwo omwe amafunikira chithandizo cha insulin.
Analogi
Maupangiri okonza zachuma akuphatikizaponso mankhwala ngati amenewa. ngati:
- Humulin Wokhazikika;
- Biosulin;
- Rinsulin;
Mafuta a Rosinsulin M ndi mankhwala ophatikizidwa a NovoMiks.
Kupita kwina mankhwala
Kodi ndingagule popanda kulandira mankhwala?
Ayi. Mankhwalawa ndi amodzi mwa mankhwala omwe mumalandira.
Mtengo wa Rosinsulin
Mtengo wa mankhwalawa umasiyanasiyana malinga ndi dera ladziko komanso ndondomeko yamalipiro ake. Mwachitsanzo, mankhwala ena otchuka pa intaneti amapereka mitengo yotsatirayi ya Rosinsulin kuchokera ma cartridge 5 a 3 ml iliyonse, yoyikidwa mu cholembera cha syringe:
- "P" - 1491.8 ma ruble;
- "C" - 1495.6 rubles;
- "M" - 1111.1 ma ruble.
Zosungidwa zamankhwala
Mankhwalawa amayenera kusungidwa m'malo owuma komanso ozizira, komwe mwayi wa ana umachepa. Cholembera, chomwe chikugwiritsidwa ntchito, chimatha kusungidwa kutentha, koma osapitilira milungu 4.
Tsiku lotha ntchito
Zaka zitatu
Wopanga
LLC Chomera Medsintez
Ndemanga za Rosinsulin
Madokotala
Dmitry, wazaka 35, Nizhny Novgorod: "Ndikhulupirira kuti kukayikira komwe kumawonetsedwa nthawi zambiri ndi odwala kupita ku mankhwala aku Russia sikulungamitsidwa. Mankhwalawa amatha kukhalabe ndi glucose wambiri komanso siwotsika poyerekeza ndi anzawo akunja. Ndimalemba ngati kuli koyenera kuti vutoli liziwoneka.
Svetlana, wazaka 40, Kirov: "Ndimaona kuti mankhwalawa ndi njira yodalirika yoperekera mankhwala a insulin kwa odwala omwe ali ndi matenda oopsa.
Anthu odwala matenda ashuga
Rosa, wazaka 53, Uchaly: "Ndidayamba kugwiritsa ntchito mankhwalawa monga momwe adanenera dokotala miyezi iwiri yapitayo. Shuga adayamba kulumpha nthawi ndi nthawi.
Victor, wazaka 49, Murom: "Ndakhala ndikupanga jakisoni wa Rosinsulin kwa chaka chathunthu, kuchokera pomwe adandipanga. Pakuyambitsaku ndimagwiritsa ntchito cholembera cholembera cha Comfort Pen chopangidwa ndi wopanga.
Kristina, wazaka 40, ku Moscow: "Kwa nthawi yayitali ndidayesa kupeza mankhwalawa okwanira mu mankhwalawa.
