Kuphatikiza kwa Amoxicillin ndi Clavulanic acid ndi amodzi mwa mankhwala omwe ali ndi antibacterial omwe ali ndi zochita zambiri. Dongosolo la malonda lamankhwala awa ndi Amoxiclav. Mankhwalawa amatha kumwedwa pokhapokha mulingo wokhazikitsidwa ndi malangizo. Izi zikuchepetsa chiopsezo chosafunidwa.
Dzina Lopanda Panther Lapadziko Lonse
Mankhwala a INN - Amoxicillin ndi Clavulanic acid.
Kuphatikiza kwa Amoxicillin ndi Clavulanic acid ndi amodzi mwa mankhwala omwe ali ndi antibacterial omwe ali ndi zochita zambiri.
Atx
Mankhwalawa ali ndi code J01CR02 pagulu la ATX lapadziko lonse lapansi.
Kutulutsa mawonekedwe ndi kapangidwe kake
Mankhwala olimbana ndi mankhwalawa amapezeka mwa mapiritsi, madontho, kuyimitsidwa ndi ufa. Mlingo wa ntchito yogwiritsidwa ntchito komanso mndandanda wazinthu zothandizira zimatengera mtundu wa mankhwalawa.
Mapiritsi
Mapiritsiwo ali ndi mawonekedwe a biconvex. Mtundu wawo ndi loyera. M'mphepete muli zolemba za yoyenera ndi kusindikiza kwa "AMC". Mankhwalawa amapangidwa pamtundu wotere wa zinthu zothandiza: 250 mg +125 mg, 500 mg + 125 mg ndi 875 mg + 125 mg. Piritsi ikadulidwa, mutha kuwona pakati, wodziwika ndi mtundu wachikaso chopepuka. Kuphatikiza apo, mapiritsi ali ndi cellulose, opadra, etc. Fomu ya mulingo imapangidwa m'matumba a 7 ma PC. 2 matuza ali ndi katoni.
Madontho
Madontho a mankhwalawa amadzaza mitsuko yagalasi 100 yagalasi. Mlingo wa zosakaniza yogwira ndi 150 mg +75 mg. Zothandiza pazinthu zomwe zimapangidwazo zimaphatikizapo madzi okonzedwa, mankhwala osungira, shuga ndi kununkhira. Fomu yotulutsayo idakonzera ana mpaka chaka chimodzi.
Mapiritsiwo ali ndi mawonekedwe a biconvex. Mtundu wawo ndi loyera.
Ufa
Ufa womwe umapangidwa kuti ukonzekere njira yothetsera jakisoni wamkati ndi yoyera kapena chikasu. Fomu ya mankhwalawa imapezeka mu 2 Mlingo wazinthu zazikulu zogwira - 500 mg + 100 mg ndi 1000 mg + 200 mg. Amayikika m'mabotolo agalasi a 10 ml.
Manyuchi
Palibe madzi omwe amapangidwa.
Kuyimitsidwa
Tsopano m'mafakitala palinso kuyimitsidwa ndi ufa woyera, womwe umapangidwa kuti akonzere fomu iyi kunyumba. Ufa umakhala ndi 125 mg + 31.25 mg / 5 ml ya chinthu chogwira ntchito. Ufa uwu umayikidwa m'matumba a translucent a 150 ml.
Zotsatira za pharmacological
Kuphatikiza kwa clavulanic acid ndi amoxicillin ndi beta-lactamase inhibitor. Mankhwala ali ndi tanthauzo la bactericidal motsutsana ndi gram-hasi ndi gram zabwino maerobes, kuphatikizapo:
- streptococcus pneumoniae haemophilus;
- staphylococcus aureus;
- pseudomonas aeruginosa;
- serratia spp;
- spinetobacter spp;
- haemophilus fuluwenza;
- escherichia coli etc.
Mankhwala ali ndi tanthauzo la bactericidal motsutsana ndi gror-aerobes ambiri.
Chida ichi chikugwira ntchito polimbana ndi tizilombo tating'onoting'ono tambiri tomwe timagwirizana ndi ma penicillin ndi cephalosporins. Mankhwalawa amagawidwa mwachangu ku ziwalo za thupi.
Pazipita ndende yogwira metabolite imatheka pafupifupi maola awiri atatha kulowetsedwa ndi mphindi 15 zokha pambuyo pakubayidwa. Kuyankhulana ndi mapuloteni amwazi kumangofika 22-30%. Kagayidwe kake ka mankhwala kogwiritsa mbali kamankhwala kamatuluka m'chiwindi. Komabe, mpaka 60% ya mankhwalawa atha kuchotsedwa popanda kusintha. Ma metabolabolites ndi zigawo zina zosasinthika za mankhwalawa zimapukutidwa ndi impso. Izi zimachedwetsedwa kwa maola 5-6.
Zisonyezero zogwiritsira ntchito amoxicillin ndi clavulanic acid
Mankhwalawa amagwiritsidwa ntchito kwambiri pothandiza matenda omwe amayambitsidwa ndi tizilombo tating'onoting'ono tokhudza zochita zake. Nthawi zambiri, mankhwala amakonzekera zochizira matenda a ziwalo za ENT, kuphatikiza:
- kupezekanso matani;
- sinusitis kuchitika pachimake ndi matenda mitundu;
- atitis media;
- pharyngeal abscess;
- pharyngitis.
Kuphatikiza apo, matenda a bronchitis omwe ali pachimake pachimake, chibayo ndi bronchopneumonia akhoza kukhala chidziwitso pakugwiritsa ntchito mankhwalawa. Mankhwala tikulimbikitsidwa osteomyelitis ndi matenda ena amfupa. Nthawi zina, mankhwalawa amalembera cholecystitis, cholangitis ndi zina zomwe zimayambitsa matenda a biliary.
Kugwiritsa ntchito mankhwalawo ndikoyenera kwa mankhwalawa a pyelonephritis, pyelitis, cystitis, gonorrhea, bacteric vaginitis, mimba ya septic, cervicitis, endometritis komanso matenda ena opatsirana a genitourinary system.
Pazovuta za mankhwala osokoneza bongo, kugwiritsa ntchito mankhwala othana ndi mankhwala nthawi zambiri kumakhala koyenera kwa peritonitis, sepsis, meningitis ndi endocarditis. Kuphatikiza apo, mankhwalawa nthawi zambiri amagwiritsidwa ntchito pochiza mabakiteriya azikhungu komanso zimakhala zofewa. Mankhwalawa amagwiritsidwa ntchito popewa zovuta za postoperative.
Contraindication
Palibe mankhwala omwe amaperekedwa kwa odwala omwe ali ndi matenda a mononucleosis, incl. ngati pali zizindikiro za chikuku. Kuphatikiza apo, phenylketonuria ndi chilolezo cha creatinine zosakwana 30 ml / mphindi ndizotsutsana pakugwiritsa ntchito mankhwalawa. Fomu lamapiritsi silikulimbikitsidwa kwa ana ochepera zaka 12.
Contraindication kuti agwiritse ntchito ndi hypersensitivity pamagawo osiyanasiyana a mankhwala. Kuletsa kugwiritsa ntchito mankhwalawa kungakhale matenda am'mimba am'mimba.
Momwe mungatenge amoxicillin ndi clavulanic acid?
Mlingo wa mankhwalawa amatengera mawonekedwe a matendawa, thanzi la wodwalayo komanso msinkhu wake. Akuluakulu amakwaniritsidwa mlingo wa 500 mg ya mankhwala 1 pa tsiku. Kwa ana, kumwa mankhwalawa amatengedwa molingana ndi kulemera.
Ndi matenda apakhungu
Ndi matenda akhungu kwambiri pakhungu, mankhwalawa nthawi zambiri amapatsidwa jekeseni. Mankhwala chikuyendetsedwera 1 ga 3 kapena 4 pa tsiku. Ndiofatsa komanso mwamphamvu kuzungulira kwa matenda, chithandizo chitha kuchitidwa monga mapiritsi. Mlingo umatha kusiyanasiyana ndi 250 mpaka 600 mg wa mankhwala patsiku. Mankhwalawa amatha mpaka masiku 14.
Ndi matenda a ziwalo za ENT
Pa matenda a ziwalo za ENT, mankhwalawa nthawi zambiri amawonetsedwa ngati mapiritsi. Akuluakulu amalangizidwa kumwa kumwa kwa 500 mg kamodzi tsiku lililonse mukatha kudya. Kutalika kwa mankhwala osachepera masiku 7.
Ndi matenda ashuga
Mankhwalawa amatha kugwiritsidwa ntchito pochiza odwala matenda a shuga. Akuluakulu omwe ali ndi vutoli, mankhwalawa amadziwitsidwa muyezo wosaposa 250 mg katatu pa tsiku. Pa mankhwala, kuwunika mosamala kuchuluka kwa shuga m'magazi kumafunika.
Ndi matenda opuma
Mankhwalawa matenda opuma, mankhwalawa amaperekedwa mu mawonekedwe a mapiritsi ndi kuyimitsidwa. Mulingo woyamwa wopatsa 250 mg katatu patsiku. Njira ya mankhwala ndi masiku 7. Ngati ndi kotheka, ikhoza kuwonjezeka mpaka masiku 10.
Ndi matenda a genitourinary system
Kwa matenda amtundu wa genitourinary, mankhwalawa amatha kuikidwa mu mawonekedwe a mapiritsi kapena jakisoni. Mlingo ndi nthawi yayitali yamankhwala zimatengera mtundu wa microflora ya pathogenic yomwe imayambitsa kutupa.
Zotsatira zoyipa za amoxicillin ndi clavulanic acid
Kugwiritsa ntchito mankhwalawa kumalumikizidwa ndi chiopsezo cha zovuta zingapo. Nthawi zambiri, odwala amakumana ndi zovuta kuchokera kugaya kwam'mimba, dongosolo lamanjenje ndi khungu. The kupezeka zovuta zimachitika amafuna malangizo a dokotala ndi kusiya zina mankhwala.
Kuchokera m'mimba
Zotsatira zoyipa zomwe zimatengedwa ndikumwa mankhwalawa m'mimba zimaphatikizanso nseru, kutsegula m'mimba, komanso kusokoneza bongo. Maonekedwe akakalendala akuda lilime ndi glossitis amatha kuonedwa. Nthawi zambiri, mukamalandira chithandizo ndi antiotic antiotic, enterocolitis ndi stomatitis imayamba. Ndi kugwiritsa ntchito mankhwala kwa nthawi yayitali, pamakhala chiopsezo cha hemorrhagic colitis ndi gastritis.
Kugwiritsa ntchito mankhwalawa kumakhudza chiwindi. Anthu omwe ali ndi vuto lachiberekero amatha kuledzera hepatitis ndi cholestatic jaundice. Makamaka nthawi zambiri, zovuta zoyipazi zimachitika ndikuphatikizidwa kwa mankhwalawa ndi maantibayotiki ena.
Kuchokera ku ziwalo za hemopoietic
Nthawi zina, motsutsana ndi maziko a mankhwalawa ndi mankhwalawa, matenda ofanana ndi seramu amayamba. Mwina chitukuko cha kusinthika kwa leukopenia ndi agranulocytosis. Thrombocytosis, kuchuluka kwa prothrombin nthawi kumaonedwa.
Kuchokera ku dongosolo lamanjenje
Mukamachita mankhwalawa pogwiritsa ntchito mankhwalawa, kuwonjezereka kwa nkhawa komanso kudandaula kwa psychomotor ndikotheka. Pakhala pali zochitika za kusowa tulo komanso vuto lachiwerewere. Kuphatikiza apo, kupweteka mutu komanso chizungulire ndizotheka. Ndi osowa kwambiri panthawi yamankhwala ndimankhwala omwe odwala amadwala komanso kusokonezeka. Kusokonezeka kwa mkhalidwe kumawoneka.
Thupi lawo siligwirizana
Thupi lawo siligwirizana chifukwa cha tsankho kwa magawo amodzi a mankhwalawa nthawi zambiri amawonetsedwa ndi urticaria ndi pruritus. Pafupipafupi, mukamamwa mankhwalawa, zizindikiro za anaphylactic mantha kapena angioedema zimawonekera. Kukula kwa allergic vasculitis ndikosowa kwambiri.
Malangizo apadera
Musanayambe kugwiritsa ntchito mankhwala osokoneza bongo, ndikofunikira kufunsa wodwalayo kuti mupeze zovuta zomwe zimayambitsa pambuyo pokhudzana ndi penicillin. Kupanda kutero, kugwiritsa ntchito mankhwalawa kuyenera kutayidwa. Ngati chiwonetsero chachikulu cha mziwopsezo chikuchitika, makonzedwe a glucocorticosteroids ndi kayendedwe ka airway angafunike.
Mosamala kwambiri, mankhwalawa ayenera kugwiritsidwa ntchito mwa odwala omwe ali ndi vuto la chiwindi. Ngati matendawo akuipiraipira, mankhwalawo ayenera kusiyidwa. Kusamala makamaka kumafunikiranso ngati wodwala wayambika ntchito yaimpso. Mukamagwiritsa ntchito mankhwalawa, muyenera kulandira chithandizo chokwanira, monga Ngati sanalandire chithandizo, pamakhala chiwopsezo cha kukhudzidwa ndi matenda opatsirana mosiyanasiyana.
Bongo
Pogwiritsa ntchito mankhwala osokoneza bongo mopitilira muyeso, zovuta zamagetsi zamagetsi am'madzi komanso zovuta zam'mimba zimatha. Zizindikiro za mankhwala osokoneza bongo zikawoneka, mankhwala othandizira amafunikira. Woopsa milandu, hemodialysis ndi mankhwala.
Kuchita ndi mankhwala ena
Kugwiritsa ntchito pamodzi kwa ma anticoagulants ndi maantibayotiki kumawonjezera mwayi wamagazi ndikutuluka kwa magazi "kuphulika". Izi zosafunika zimachitika komanso kuphatikizidwa kwa antibacterial wothandizila ndi njira yolerera pakamwa. Mitundu yosiyanasiyana ya diuretics, mankhwala osapweteka a antiidal, Allopurinol, Phenylbutazone ndi mankhwala ena omwe amachepetsa kusefukira kwa glomerular, akagwiritsidwa ntchito limodzi ndi maantibayotiki, amatsogolera kuchuluka kwa amoxicillin.
Kuyenderana ndi mowa
Maantibayotiki sangaphatikizidwe ndi mowa. Izi zimawonjezera chiopsezo chodana ndi zovuta.
Analogi
Mankhwala omwe ali ndi vutoli ofanana ndi awa:
- Augmentin.
- Arlet
- Panclave.
- Amoxiclav Quicktab.
- Lyclav.
- Mochulukitsa.
- Flemoklav.
- Verklav.
- Baktoklav.
Mtengo
Mtengo wa mankhwala opha maantibayotiki m'mapiritsi amachokera ku ma ruble 45 mpaka 98.
Malo osungira
Mankhwala okhala ngati ufa ndi mapiritsi amayenera kusungidwa m'malo owuma pamawonekedwe a +25 ° C. Kuyimitsidwa kothiriridwa kumatha kusungidwa osaposa masiku 7 pa kutentha kosaposa +6 ° C.
Tsiku lotha ntchito
Mutha kusunga mankhwalawa ngati ufa ndi mapiritsi a 2 years.
Wopanga
Mankhwalawa amapangidwa ndi opanga mankhwala awa:
- Sandoz GmbH (Austria).
- Lek dd (Slovenia).
- PJSC "Krasfarma" (Russia).
Ndemanga
Mankhwala othana ndi mankhwalawa akhala akugwiritsidwa ntchito kwachipatala, motero ndinapeza ndemanga zambiri kuchokera kwa madokotala ndi odwala omwe adazigwiritsa ntchito.
Malingaliro a madotolo
Svetlana, wa zaka 32, Vladivostok.
Monga otolaryngologist, nthawi zambiri ndimapereka mankhwala awa kwa odwala omwe ali ndi otitis media. Mankhwala amakulolani kuthetsa mwachangu microflora ya pathogenic yomwe imayambitsa kutupa. Mankhwala amachepetsa chiopsezo cha zovuta. Imalekereredwa bwino ndi odwala ambiri.
Irina, wazaka 43, Moscow
Ndakhala ndikugwira ntchito ngati mwana kwa zaka zoposa 15. Nthawi zambiri, odwala ang'onoang'ono amayenera kupatsidwa mankhwala opha tizilombo. Kukonzekera kwa Amoxicillin ndi Clavulanic acid kwatsimikizira bwino. Kuyimitsako kumakoma, chifukwa makolo alibe vuto ndi kuleka kwa mwana kumeza mankhwalawo. Zotsatira zoyipa ndizosowa kwambiri poyerekeza ndi mankhwala ena.
Odwala
Igor, wazaka 22, Omsk
Pafupifupi chaka chapitacho adadwala atitis media. Zosangalatsa m'makutu zimaletsa kugona komanso kudya wamba. Mankhwala opha mabakiteriya anapatsidwa ndi dokotala. Ndimamva kusintha tsiku limodzi. Anamwa mankhwalawa masiku 7. Zina mwa zoyipa zomwe zimadziwika mu kugona kwake. Zomwe zimagwiritsidwa ntchito ndi maantibayotiki zimakwaniritsidwa.
Kristina, wazaka 49, Rostov-on-Don
Ankachita ndi mankhwala a cystitis. Mankhwala ena sanathandize. Patatha masiku ochepa ndimamwa mankhwalawa, ndinayamba kusintha. Mankhwalawa adatengedwa kwa masiku 14. Mawonekedwe a cystitis adasowa.
Olga, wa zaka 32, Krasnodar
Ntchito mankhwalawa mankhwalawa chibayo. Dokotala anali atapereka chithandizo. Ngakhale kuti matendawa adayamba kuyenda bwino atangoyamba kumene chithandizo, zotsatirapo zina zakumwa zimadziwika. Munthawi yonse yogwiritsa ntchito mankhwalawa, ndinali kuda nkhawa ndi nseru ndi matenda am'mimba. Ngakhale panali zovuta zina, ndinamwa mankhwalawa kwa masiku 7. Mankhwala ochiritsa chibayo, koma kenako ndimamwa ma protein.
