Mwa mankhwala omwe amagwiritsidwa ntchito pochiza matenda ashuga, mankhwala omwe amatchedwa Onglisa amadziwika.
Ndikofunika kuphunzira malangizo a mankhwalawa, kuzindikira mawonekedwe ake ndi mapindu ake, komanso kudziwa njira zomwe zingathandizire kupewa zoyipa chifukwa chogwiritsa ntchito molakwika.
Zambiri, kapangidwe ndi mawonekedwe ake amasulidwe
Mankhwala a shuga amapezeka ku United States. Amapangidwa kuti azilamulira odwala omwe ali ndi shuga. Ili ndi vuto la hypoglycemic. Gwiritsani ntchito kuyenera kuvomerezeka ndi dokotala, kuti musavulaze thanzi lanu. Ichi ndichifukwa chake mutha kugula Ongliz kokha ndi mankhwala.
Maziko a mankhwalawa ndi mankhwala a Saksagliptin. Imagwira ntchito yayikulu mu mankhwalawa. Gawo limagwiritsidwa ntchito kuyimitsa zizindikiro za hyperglycemia pochepetsa kuchuluka kwa shuga m'magazi.
Ngati wodwalayo aphwanya malangizo azachipatala, ndiye kuti mankhwalawo amatha kuyambitsa zovuta komanso zovuta.
Zomwe akuphatikizidwazo zimaphatikizapo zinthu zothandiza:
- lactose monohydrate;
- croscarmellose sodium;
- hydrochloric acid;
- stesiate magnesium.
Kuphatikiza apo, mankhwalawa amakhala ndi utoto wocheperako, womwe umafunikira kuti apange filimu yophimba miyala (mankhwalawo ali ndi mawonekedwe a piritsi). Amatha kukhala achikasu kapena ofiira okhala ndi zojambula zamtambo. Pogulitsa, mutha kupeza mapiritsi okhala ndi muyeso wa 2,5 ndi 5 mg. Onsewa amagulitsidwa m'matumba amtundu wa ma PC 10. Mapaketi atatu oterewa amayikidwa mu paketi.
Pharmacology ndi pharmacokinetics
Mphamvu ya mankhwalawa pa odwala matenda ashuga ndi chifukwa cha zomwe zimachitika. Ikalowa mthupi, saxagliptin imalepheretsa enzyme DPP-4. Zotsatira zake, maselo a pancreatic beta amathandizira kaphatikizidwe ka insulin. Kuchuluka kwa glucagon panthawiyi kumachepa.
Chifukwa cha izi, kuchuluka kwa shuga m'magazi a wodwalayo kumachepetsedwa, zomwe zimapangitsa kuti zinthu zikhale bwino (pokhapokha mlingo wake umatsika mpaka pamavuto). Chofunikira kwambiri pazinthu zomwe zikufunsidwa ndizoperewera pa thupi la wodwalayo. Odwala omwe amagwiritsa ntchito Ongliza samonda.
Kumwirira kwa saxagliptin kumachitika mwachangu ngati mumwa mankhwalawa musanadye. Nthawi yomweyo, gawo lalikulu la chinthu chogwira ntchito limamwa.
Saksagliptin alibe chizolowezi cholowa m'magazi a m'magazi - mawonekedwe a maubwenzi awa amakhudza gawo laling'ono la chinthucho. Kuchuluka kwa mankhwalawa kumatheka mu pafupifupi maola awiri (ziwalo za thupi zimakhudza izi). Zimatenga pafupifupi maola atatu kuti muchepetse theka la Saxagliptin lomwe likubwera.
Zizindikiro ndi contraindication
Ndikofunika kwambiri kutsatira malangizo okhudzana ndi zofunikira zoika mankhwalawo. Kugwiritsidwa ntchito kwa Onglises kumadzetsa chiopsezo ku thanzi ndi moyo. Mankhwala okhala ndi vuto la hypoglycemic ayenera kugwiritsidwa ntchito kokha kwa anthu omwe ali ndi kuchuluka kwa shuga, chifukwa kwa ena chithandizo ichi ndi chovulaza.
Izi zikutanthauza kuti chizindikiro cha mankhwalawa ndi mtundu wachiwiri wa matenda ashuga. Chidachi chimagwiritsidwa ntchito ngati zakudya ndi zolimbitsa thupi sizingakhudzidwe ndi shuga.
Mungathe kugwiritsidwa ntchito mwanjira ina komanso mosiyanasiyana ndi mankhwala ena (Metformin, sulfonylurea derivatives, etc.).
Mankhwalawa ali ndi zotsutsana:
- mtundu 1 shuga;
- mimba
- kudya kwachilengedwe;
- matupi awo sagwirizana ndi mankhwala;
- kuchepa kwa lactase;
- ketoacidosis yoyambitsidwa ndi matenda ashuga;
- galactose tsankho.
Kukhalapo kwa chinthu chimodzi kuchokera pamndandanda ndi chifukwa chokana kugwiritsa ntchito mapiritsi.
Gawaninso magulu aanthu omwe amaloledwa kugwiritsa ntchito Onglisa, koma moyang'aniridwa mosamala ndi madokotala. Izi zimaphatikizapo okalamba, komanso odwala omwe amalephera impso.
Malangizo ogwiritsira ntchito
Gwiritsani ntchito mankhwalawa malinga ndi malamulo. Ngati dotolo sanatchule mlingo wina, ndiye kuti wodwalayo ayenera kugwiritsa ntchito 5 mg ya mankhwalawa patsiku. Mlingo wofanana umalimbikitsidwa ndikuphatikizidwa kwa Onglisa ndi Metformin (kutumikiridwa kwa Metformin tsiku lililonse ndi 500 mg).
Kugwiritsa ntchito mankhwalawa kumangokhala mkati. Ponena za kudya, palibe chomwe mungasonyeze; mumatha kumwa mapiritsi musanadye komanso mutatha kudya. Cholinga chokha ndikugwiritsa ntchito mankhwalawa pawotchi.
Mukadumpha mlingo wotsatira, simuyenera kudikirira nthawi yokhayo yoti mumwe mankhwala awiri. M'pofunika kumwa mankhwalawa mwachizolowezi pomwe wodwala amakumbukira.
Malangizo apadera
Mavuto omwe angakhalepo atha kupewedwa mwa kuwona njira zopewera kusamala kwa anthu omwe ali ndi matenda otsatirawa:
- Kulephera kwina. Ngati matendawa ndi ofatsa, simuyenera kusintha mankhwalawa. Koma nthawi yomweyo, muyenera kupenda impso nthawi ndi nthawi. Ndi gawo loyenera kapena loopsa la matendawa, ndikofunikira kuti mupereke mankhwala muyezo wochepetsedwa.
- Kulephera kwa chiwindi. Nthawi zambiri, mankhwala a hypoglycemic amakhudza chiwindi, kotero akagwiritsidwa ntchito ndi odwala omwe ali ndi vuto la chiwindi, ndikofunikira kusintha mlingo wa mankhwalawa. Ponena za Onglisa, izi sizofunikira, odwala awa amatha kugwiritsa ntchito mankhwalawa malinga ndi ndondomeko yanthawi zonse.
Mankhwala sangathe kulepheretsa kugwirizana kwa kayendedwe, kuthamanga kwa kayendedwe, etc. Koma izi zitha kufooka ndi kukula kwa boma la hypoglycemic. Chifukwa chake, mukamagwiritsa ntchito mankhwalawa muyenera kusamala mukamayendetsa.
Zotsatira zoyipa ndi bongo
Kupezeka kwa mavuto obwera chifukwa chogwiritsidwa ntchito ndi Onglisa sikugwirizana nthawi zonse ndi kusalolera kwake. Nthawi zina amayamba chifukwa chamoyo chomwe sichinabatizidwe. Komabe, ngati atapezeka, tikulimbikitsidwa kudziwitsa adotolo za iwo.
Malangizo a mankhwalawa amawonetsa mavuto monga:
- matenda a kwamkodzo thirakiti;
- mutu
- nseru
- kupweteka m'mimba;
- sinusitis
- nasopharyngitis (munthawi yomweyo kugwiritsa ntchito ndi metformin).
Chithandizo cha Syndrome chimagwiritsidwa ntchito pochotsa mavuto awa. Nthawi zina, dokotala amachotsa mankhwalawo.
Palibe chidziwitso chokhudza mankhwala osokoneza bongo omwe ali ndi mankhwalawa. Ngati zichitika, chithandizo chamankhwala ndichofunikira.
Kuyanjana Ndi Mankhwala Ndi Analogi
Kugwiritsa ntchito munthawi yomweyo kwa Onglisa ndi mankhwala ena kumafuna kuchuluka kwamphamvu, chifukwa ntchito ya Saxagliptin imachepa.
Ndalamazi ndi monga:
- Rifampicin;
- Dexamethasone;
- Phenobarbital, etc.
Ndikulimbikitsidwa kuchepetsa mulingo wa Onglisa akagwiritsidwa ntchito limodzi ndi zotumphukira za sulfonylurea.
Mankhwala omwe amathanso kumwa mankhwalawa akuphatikizapo:
- Galvus;
- Januvius;
- Nesina.
Popanda kutsimikizira kwa katswiri, kugwiritsa ntchito chilichonse mwazida izi ndizoletsedwa.
Maganizo a odwala
Pambuyo pophunzira ndemanga za mankhwala a Onglisa, titha kunena kuti mankhwalawa amachepetsa kuchuluka kwa shuga m'magazi, koma siabwino kwa aliyense ndipo amafunikira njira yolowera payekha ndi kuwongolera.
Zotsatira za mankhwalawa ndi zabwino kwambiri. Shuga wanga wakhazikika tsopano, kunalibe zotsatirapo zake ndipo ayi. Kuphatikiza apo, ndizosavuta kugwiritsa ntchito.
Dmitry, wazaka 44
Mankhwala a Ongliz amandiwona ngati ofooka. Mlingo wa shuga sunasinthe, kuwonjezera apo, ndinazunzidwa ndi mutu wokhazikika - mwachionekere, zotsatira zoyipa. Ndinatenga mwezi ndipo sindimatha kupirira, ndimayenera kupempha mankhwala ena.
Alexander, wazaka 36
Ndakhala ndikugwiritsa ntchito Onglise kwa zaka zitatu. Kwa ine, ichi ndiye chida chabwino kwambiri. Asanamwe mankhwala osiyanasiyana, koma mwina zotsatirazo zinali zochepa kwambiri, kapena adazunzidwa ndi zovuta. Tsopano palibe vuto lotere.
Irina, wazaka 41
Phunziro la kanema pamankhwala atsopano a shuga:
Mankhwalawa ndi amodzi mwa okwera mtengo - mtengo uliwonse ndi 30 ma PC. pafupifupi 1700-2000 rub. Kuti mupeze ndalama, muyenera kulandira mankhwala.
