Zikondamoyo ndiye gwero lalikulu la zinthu za enzyme zomwe zimathandizira kugaya mapuloteni, mafuta ndi chakudya. Madzi a pancreatic amakhala ndi lipase, amylase, trypsin ndi chymotrypsin, komanso ma bicarbonate ion omwe amalepheretsa zinthu zam'mimba zam'mimba.
Zizindikiro za vuto la enzyme
Zikondazo zimatha kusinthana ndi chakudya ndipo zimapanga ma enzyme ambiri momwe amafunikira kuti chimbudzi chikhale bwino. Chifukwa chake, mwachitsanzo, ndi kuchuluka kwa zakudya zam'matumbo, amylase imabisidwa, trypsin yochulukirapo imafunikira pokonza mapuloteni, komanso kugwiritsa ntchito zakudya zamafuta kumathandizira kupanga lipase.
Mothandizidwa ndi zinthu zingapo, ntchito ya kapamba imatha kuchepa, yomwe imayendetsedwa ndi kuwonongeka mu chimbudzi chifukwa chosowa ma enzyme. Kuphwanya katulutsidwe ndi kuchepa kwa michere nthawi zambiri kumachitika chifukwa cha kapamba, pomwe chiwalo chimadzaza, ndipo minyewa yake m'malo mwake imasinthidwa pang'ono ndi minofu yolumikizika.
Kuwonongeka kwa kapamba kumayendetsedwa ndi izi:
- kupweteka kwam'mimba pamimba;
- kuchuluka thukuta ndi tachycardia;
- malungo ndi kufooka wamba;
- khungu kamvekedwe ka khungu ndi sclera;
- kudzimbidwa, mseru komanso kusanza.
Kukonzekera kwamakono kwamankhwala kumapangidwa kuchokera ku zikondamoyo za ng'ombe ndi nkhumba; Kuchita kwawo kumatengera mtundu wa kumasulidwa ndi mlingo
Ndikothekanso kudziwa kuti ndi enzyme iti yomwe ikusowa ndi maonekedwe ndi mawonekedwe a pondapo. Chifukwa chake, ndikusowa kwa amylase, kukakamiza kulekerera kumachulukirachulukira, chopondacho chimakhala chamadzi chifukwa cha malabsorption m'matumbo aang'ono. Zopatsa mphamvu zamagalimoto, kuchepa kwa mavitamini ndi kuchepa thupi zimawonedwa.
Kuperewera kwa lipase kumayendera limodzi ndi chikhalidwe chotchedwa steatorrhea, pomwe kuchuluka kwa mafuta m'zimbudzi kumawonjezeka. Mtundu wa pondapo umasintha kukhala wachikasu kapena lalanje, kusinthasintha kumakhala kadzoni wamafuta.
Kuperewera kwa trypsin kumakhudza kupezeka kwa ulusi wosalowetsedwa mu ndowe, zomwe nthawi zambiri zimayambitsa kuwoneka kwa magazi.
Zolemba ntchito
Ndi kuwoneka pafupipafupi kwa ululu, munthu amazolowera, komwe kumakhala kowala ndi kukula kwa necrosis komanso zovuta zina. Kuti mupewe izi, ndikofunikira kuyambitsa chithandizo munthawi yake ndikubwezeretsanso ntchito ya pancreatic exocrine.
Ma Enzymes ndi mapuloteni okhala ndi mavitamini, michere ndi zinthu zina zopindulitsa. Amakhalapo mokwanira mu zinthu zachilengedwe (nyama, mkaka, batala). Komabe, izi sizokwanira, popeza mapuloteni aliwonse amawonongedwa ndi chithandizo cha kutentha.
Ichi ndichifukwa chake kukonzekera kwamphamvu kwa kapamba, komwe amapezeka m'mapiritsi kapena makapisozi, ndikofunikira. Kodi amagwira ntchito bwanji? Mutatha kumwa mankhwalawa, kupanga michere ndi kapamba kumachepa, ndipo kukakamira kwa ma pancreatic kumachepa. Zotsatira zake, kutupa kwa thupi kumachepa ndipo kuwonongeka kwake kumachepera.
Piritsi likasungunuka m'matumbo, chizindikiritso chimaperekedwa ku ubongo wonena za kuchuluka kwa kuchuluka kwa enzyme, komwe kumapangitsa kuti chithandizo chiziwononga. Komabe, mapiritsi ena amakoka: mu acidic pamimba, chipolopolo chake chimasungunuka kapena kupasuka kwathunthu, ndipo mankhwalawo amafikira matumbo osinthika. Chifukwa chake, mapiritsi okhala ndi enzyme amalimbikitsidwa kuti amwe limodzi ndi ma antacid omwe amachepetsa acidity yam'mimba.
Atalandira zotsatira za mayesowo, adotolo atha kukulembera kukonzekera kwa enzyme kapena antienzyme. Zotsirizazo ndizofunikira pancreatic hyperfunction, pamene michere yowonjezera imapangidwa.
Kuchiza ndi michere ya pancreatic kumachitika kwa nthawi yayitali. Ngati pancreatitis amadziwika kuti ali pachimake, ndiye kuti amawapatsa mankhwala kwa miyezi isanu ndi umodzi mpaka chaka chimodzi. Mwanthawi yayitali matenda, ma enzyme amatengedwa mosalekeza, osasokoneza.
Ndi kuchulukirachulukira kwa kapamba, mankhwalawa amayeneranso kusiyidwa, chifukwa izi zitha kukulitsa vutolo ndikukulitsa ululu.
Kukonzekereratu kumalimbikitsidwa kuti mugwiritse ntchito limodzi mukalakwitsa zakudya, mukamaphatikizana ndi kutentha kwa mtima, kusweka mtima kapena mseru. Ngati zochitika zotere zimawonedwa mwadongosolo, ndiye kuti ndikofunikira kuti zitsimikizire magwiridwe antchito a kapamba, atapena mayeso. Sikovuta kuchita izi, ndikokwanira kungoyesa magazi a biochemical.
Tiyeneranso kudziwa kuti kugwiritsa ntchito ma enzymes sikumangotanthauza matenda a kapamba, komanso kubwezeretsa ntchito za ziwalo zina - m'mimba, matumbo ndi chikhodzodzo. Chifukwa chake, zitha kutchulidwa mu izi:
- zilonda, gastritis, gastroduodenitis;
- matenda a ndulu;
- matumbo pathologies;
- ntchito dyspeptic matenda.
Zizindikiro zogwiritsidwa ntchito ndi nthawi yokonzanso pambuyo pakuchita opaleshoni ziwalo zam'mimba, mwachitsanzo, kuphatikizika kwa ndulu.
Zosiyanasiyana
Ma Enzymatic othandizira ndiwo maziko a chithandizo chamankhwala, chomwe chitha kukhala chothandiza kwambiri kuphatikiza ndi chithandizo chamankhwala. Mndandanda wa mankhwala omwe agwiritsidwa ntchito ndi awa:
- Pancreatin, Pangrol, Panzinorm, Pancreon, Penzital, Pancreoflat, Pancurmen, Pankral, Pepfiz;
- Mezim-forte, Merkenzyme, Wobenzym, Phlozenzyme, Unienzyme, Kotazim-forte;
- Nygedase, Oraza, Somilase;
- Abomin, Betaine;
- Cadistal, Ipental, Digestal, Festal, Enzistal.
Pancreatic secretion imapangidwa m'thupi la kapamba, mahomoni monga insulin ndi glucagon amapangidwa m'chigawo cha mchira
Mankhwala onsewa ali ndi zamagetsi zambiri zomwe zimakhala ndi zosakaniza chimodzi kapena zingapo. Popeza kukonzekera kuli ndi mlingo wosiyana ndi kapangidwe kake, kugwiritsa ntchito pawokha kumabweretsa mavuto m'malo mopindulitsa. Ndi iti yomwe imagwira ntchito bwino komanso mwachangu - dokotala wasankha.
M'masiku oyamba pambuyo povulaza pachimake kapamba, kusala kudya kumayerekedwa kwa tsiku kapena kuposerapo. Kenako, pakakhala ma enzyme ochulukirapo, adokotala amatha kukupatsani mankhwala opha ziwindi
Zizindikiro zakukula kwa kapamba - Aminocaproic acid epsilon;
- Somatostatin;
- Vasopressin;
- Ingitrile;
- Isoprenaline;
- Kalcitonin;
- Contrakal ndi ena.
Malangizo othandizira azakudya ndi awa: zakudya zamafuta ochepa chabe zomwe zimakhala ndi nyama yochepa, chimanga chamadzimadzi ndi msuzi wosenda. Muyenera kumwa zamchere zamchere zamchere zopanda mpweya, mpaka malita awiri patsiku.
Pancreatin
Pancreatin ilinso ndi zomwe zimagwira, zomwe zimaphatikizapo amylase, lipase ndi proteinase. Ubwino wa mankhwalawa ndiwotchipa komanso wogwira ntchito kwambiri osakwanira pancreatic ntchito.
Mothandizidwa ndi Pancreatin, njira yogaya chakudya imakhala bwino ndipo zotsatira zoyipa sizimachitika kawirikawiri. Kuphatikiza apo, mankhwalawa samakhudza gallbladder ndipo samalimbikitsa kapangidwe ka bile. Mlingo wa kapamba zimadalira msika wa wodwala komanso kuchuluka kwa kuwonongeka kwa kapamba. Pa avareji, ndimayunitsi okwana 150,000 / tsiku, mlingo waukulu ndi mayunitsi 400,000 / tsiku.
Mezim Forte
Mankhwalawa amakhalanso ndi pancreatin, koma pamlingo wokwera kwambiri. Pali mitundu itatu - Mezim, Mezim-forte ndi Mezim-20000. Amasiyana mu kuchuluka kwa lipase pamapangidwe awo:
- Mezim - 3500 mayunitsi;
- Mezim-forte - magawo 10,000;
- Mezim 20,000 - 20,000;
Monga Pancreatin, mitundu yonse ya Mezim imakhala, kuwonjezera pa lipase, amylase ndi proteinase, komanso trypsin ndi chymotrypsin. Kumbukirani kuti mankhwalawa ali ndi ma enzyme omwe angawononge mawonekedwe amkamwa atsekemera. Chifukwa chake, ayenera kumwedwa popanda kutafuna. Zofanizira za Mezim ndi Creon, Pangrol ndi Pancreasim.
Mankhwala sangathe kumwa ndi pachimake kapamba ndi kufalikira kwa aakulu. Mlingo wokhazikika umodzi ndi mapiritsi 1-2, ndikuwonongeka kwakukulu kwa kapamba, umakulitsidwa kumapiritsi 4.
Panzinorm imathandizira kulipirira kuchepa kwa ntchito ya exocrine ndipo imapezeka m'mapiritsi kapena makapisozi okhala ndi chipolopolo chosagwira asidi
Chiboni
Ubwino wa Creon ndi mawonekedwe ake omasulira - pancreatin wosweka, woyikidwa mu kapisozi wodalirika. Mu kapisolo uyu pali ma microspheres aang'ono mainchesi. Pambuyo pakulowetsa, kapisoziyo imasungunuka ndi madzi am'mimba, ndipo ma microspheres omwe atulutsidwawo amapitabe njira yawo yolowera matumbo, osakumana ndi malo ankhalwe.
Pancreatin ma microspheres amagwira ntchito mu duodenum, amalowa pakukhudzana ndi mankhwala a catabolism a mafuta, mapuloteni ndi chakudya. Ubwino wa ma microspheres ndikuti mankhwalawo omwe amapezeka m'maguluwo amakhala osakanikirana ndi chakudya ndikugawidwa pamatumbo.
Mipira ya mini ya Creon imafika m'matumbo mwachangu ndikuchita zina chifukwa cha chipolopolo chawo. Mankhwalawa akupezeka mu kipimo cha 10,000, 25,000 ndi 40,000, zomwe zimaloleza kuti zigwiritsidwe ntchito kwambiri m'matumbo a kapamba.
Unienzyme ndi kaphatikizidwe kamapangidwe kamene kamakhala ndi kake kamene kamachepetsa
Festal, Enzystal ndi Normoenzyme
Festal imapezeka ngati mapiritsi okhala ndi mankhwala okhala ndi pancreatin ndi bovine bile, omwe amathandiza kupasuka ndi mafuta a adsorb. Kuphatikiza apo, Festal imakhala ndi hemicellulose, yomwe imathandizira kugaya kwa fiber. Izi zimathandizira kufalikira ndi kusanja.
Mapiritsi a Enzistal ndi analogue a Festal, koma ndi otsika mtengo. Pogula, muyenera kuyang'anira ma CD ndi dzina lenileni la mankhwalawo, chifukwa palinso Enzistal-P. Ndi yosiyana kwambiri pakupanga ndipo imakhala ndi chinthu chimodzi chogwira - Pakreatin. Pomwe Enzystal ndi mankhwala ofanana atatu monga Festal. Normoenzyme ndi analogue ina ya Festal, yomwe imadziwika ndi mawonekedwe amylase okwanira 5000 mayunitsi.
Wobenzym
Madokotala ambiri amawona kuti Wobenzym ndi mankhwala othandiza kwambiri, omwe ali ndi zofunikira zingapo pakuphatikizika kwake:
- kapamba;
- bromelain;
- trypsin;
- chymotrypsin;
- papain;
- rutoside (rutin).
Wobenzym ndi mitundu yosiyanasiyana ya michere ya nyama ndi chomera komanso kuwonjezera kwa rutoside
Bromelain ndi puloteni ya proteinolytic yomwe imaphwanya mtundu wa mapuloteni ngati protamine sulfate. Kuphatikiza apo, bromelain imakhala ndi anti-yotupa ndi antiaggregant (kupatulira magazi), komanso kuthamangitsa minofu kusinthika.
Rutoside ndi vitamini, bioflavonoid, yomwe imapangitsa kuti capillaries ikhale ndi mphamvu komanso kuti isawonongeke. Pa chimbudzi, rutin imasinthidwa kukhala quercetin, antioxidant wachilengedwe.
Ubwino wa Wobenzym umaphatikizapo kusakhalapo kwathunthu kwa zotsatira zoyipa, zomwe zimawonedwa pokhapokha pokhapokha ngati pali tsankho.
Chifukwa chake, pali mankhwala ambiri omwe amathandiza kudzaza kuchepa kwa ma enzyme ndikubwezeretsanso ntchito yapancino. Yemwe mungasankhe zimatengera momwe muliri ndi zotsatira za mayeso. Khalani athanzi!
