Momwe mungatengere Diabeteson MV (60 mg) ndi mawonekedwe ake

Odwala omwe ali ndi mtundu wachiwiri wa shuga safunikira jakisoni wa insulin kwa nthawi yayitali, ndipo ambiri aiwo amatha kulipiridwira chifukwa cha mapiritsi ochepetsa shuga. Diabeteson MV 60 mg ndi imodzi mwanjira zotere, zimachitika chifukwa cha kukonzekera kwake pakupanga insulin. Kuphatikiza pa kukhudza kagayidwe kazakudya, Diabeteson imateteza ndi kubwezeretsa m'mitsempha yamagazi, imapangitsa kukhazikika kwa makoma awo, komanso kupewa atherosulinosis.

Mankhwalawa ndi osavuta kutenga ndipo ali ndi zovuta zochepa, chifukwa zimagwiritsidwa ntchito kwambiri pothandizira matenda a shuga. Ngakhale mukuwoneka kuti ndinu otetezeka, simungathe kumwa popanda kuvomerezedwa ndi dokotala kapena kupitilira muyeso. Chofunikira kuti a Diabeteson akhazikitsidwe ndikusowa kwa insulini yake yomwe. Pancreas ikugwira ntchito moyenera, makonda ayenera kuperekedwa kwa othandizira ena a hypoglycemic.

Kodi mankhwalawa amagwira ntchito bwanji?

Diabetes imakhala ndi mankhwala m'thupi la odwala matenda ashuga chifukwa cha glycazide pamagulu ake. Zigawo zina zonse za mankhwalawa ndi zothandiza, chifukwa cha iwo kapangidwe ka piritsi ndi kuyamwa kwake kwakanthawi kumatsimikizika. Gliclazide ndi m'gulu la sulfonylureas. Mulinso zinthu zingapo zokhala ndi katundu wofanana; ku Russia, kuwonjezera pa gliclazide, glibenclamide, glimeperide, ndi glycvidone ndizofala.

Matenda a shuga ndi kupsinjika kudzakhala chinthu chakale

• Matenda a shuga -95%
• Kuthetsa kwa mitsempha thrombosis - 70%
• Kuthetsa kwa kugunda kwamtima kwamphamvu -90%
• Kuthana ndi kuthamanga kwa magazi - 92%
• Kuwonjezeka kwa mphamvu masana, kukonza kugona usiku -97%

Mphamvu zochepetsera shuga za mankhwalawa zimatengera zotsatira zawo pamaselo a beta. Awa ndi mapangidwe a kapamba omwe amapanga insulin. Pambuyo potenga Diabeteson, kumasulidwa kwa insulin m'magazi kumawonjezeka, pomwe shuga amachepetsedwa.

Matenda a kishuga amagwira ntchito pokhapokha maselo a beta alipo amoyo koma akachitabe ntchito yawo pang'ono. Chifukwa chake mankhwalawa osagwiritsidwa ntchito pa matenda a shuga 1. Cholinga chake ndi chosafunika nthawi yoyamba pambuyo pa kuwonekera kwa matenda a mtundu 2. Mtunduwu wa shuga umadziwika ndi kupanga kwambiri insulin kumayambiriro kwa zovuta zamatumbo, kenako kuwonongeka pang'onopang'ono patatha zaka zochepa.

Mkulu shuga poyamba amayamba chifukwa cha kukana insulini, i.e, malingaliro abwinobwino a insulin. Chizindikiro chachikulu cha kukana insulini ndicholemera kwambiri mwa wodwala. Chifukwa chake, ngati kunenepa kwambiri kumawonedwa, odwala matenda ashuga satchulidwa. Pakadali pano, mankhwala omwe amachepetsa kukana, monga Metformin (mlingo kuchokera 850 mg), amafunikira. Diabeteson imaphatikizidwa mu regimen yothandizira ngati kuwonongeka kwa ntchito ya maselo a beta kukhazikitsidwa. Itha kuzindikirika pogwiritsa ntchito kusanthula kwa c-peptide. Ngati zotsatira zake zili m'munsimu 0,26 mmol / L, kusankhidwa kwa Diabeteson kuli koyenera.

Chifukwa cha chida ichi, kupanga kwa insulin mu matenda a shuga kuyandikira kwambiri kwachilengedwe: nsonga ya katulutsidwe imabweranso poyankha glucose yemwe amalowa m'magazi kuchokera ku chakudya cha carbohydrate, kupanga kwa mahomoni mu gawo lachiwiri kumalimbikitsidwa.

Kuphatikiza pakulimbikitsa maselo a beta, Diabeteson ndi mapiritsi ena a gliclazide ali ndi gawo lalikulu pa kukula kwa kusintha kwa ma atherosselotic m'mitsempha yamagazi:

1. Chitani zinthu ngati antioxidant. Matenda a shuga amadziwika ndi kuchuluka kwa zopitilira muyeso komanso kufooketsa chitetezo cha maselo pazotsatira zawo. Chifukwa cha kukhalapo kwa gulu la aminoazobicyclooctane mu molekyulu ya gliclazide, ma radicals owopsa ndiopanda tsankho. Mphamvu ya antioxidant imawonekera kwambiri m'magulu ang'onoang'ono, kotero mukamamwa diabetes, zizindikiro zimayendetsedwa bwino ndi odwala a retinopathy ndi nephropathy.
2. Bwezeretsani katundu wa mtima endothelium. Izi ndichifukwa cha kuchuluka kwa nitric oxide m'makoma awo.
3. Kuchepetsa chiopsezo cha thrombosis, chifukwa amachepetsa kuthekera kwa maplatelete kumamatira wina ndi mnzake.

Kuchita bwino kwa odwala matenda ashuga kumatsimikiziridwa ndi kafukufuku. Mukamagwiritsa ntchito mlingo wa 120 mg, kuchepa kwapafupipafupi kwa zovuta zamatenda a shuga ndi 10% kunadziwika. Mankhwalawa adawonetsa zotsatira zabwino moteteza impso, chiopsezo cha nephropathy chatsika ndi 21%, proteinuria - ndi 30%.

Kwa nthawi yayitali anthu amakhulupirira kuti zochokera ku sulfonylurea zimathandizira kuwonongeka kwa maselo a beta, motero kupititsa patsogolo kwa matenda ashuga. Tsopano zadziwika kuti sizili choncho. Mukayamba kumwa Diabeteson MV 60 mg, kuwonjezeka kwa insulin chifukwa cha 30% kumawonedwa, ndiye kuti chaka chilichonse chisonyezochi chimatsika ndi 5%. Odwala omwe amawongolera shuga kokha ndi zakudya kapena zakudya ndi metformin, zaka 2 zoyambirira za kuchepa kwa kaphatikizidwe sizimawonedwa, ndiye pafupifupi 4% pachaka.

Malangizo ogwiritsira ntchito Diabeteson MV

Makalata MV m'dzina la mankhwalawa akuwonetsa kuti ndiwotulutsa wosinthika (Chingerezi cha MR - kumasulidwa kosinthidwa). Piritsi, chinthu chogwiritsidwa ntchito chimayikidwa pakati pa ulusi wa hypromellose, womwe m'matumbo am'mimba amapanga gel. Chifukwa cha kapangidwe kameneka, mankhwalawa amamasulidwa nthawi yayitali, machitidwe ake akukwanira tsiku limodzi. Diabeteson MV imapezeka mu mapiritsi; piritsi mukagawika magawo, mankhwalawa sataya nthawi yayitali.

Mlingo wa 30 ndi 60 mg wagulitsidwa. Imwani kamodzi patsiku, nthawi yabwino kwambiri pakudya m'mawa. Piritsi imatha kuthyoledwa pakati kuti muchepetse mulingo, koma osatheka kuthungidwa kapena kusunthidwa.

Mwachizolowezi, osati MV, Diabetes amapezeka ndi kuchuluka kwa gliclazide - 80 mg, amamwa kawiri patsiku. Pakadali pano, amaonedwa ngati wopanda ntchito ndipo sangagwiritse ntchito, popeza kukonzekera kwanthawi yayitali kumapereka tanthauzo lotere.

Diabetes imayenda bwino ndi othandizira ena a hypoglycemic. Nthawi zambiri, imapangidwa limodzi ndi Metformin. Ngati kukondoweza kwa insulin sikokwanira, ndi matenda a shuga 2, mapiritsi angagwiritsidwe ntchito ndi jakisoni wa insulin.

Mlingo woyambirira wa Diabetes, mosasamala za msinkhu komanso gawo la matenda odwala matenda ashuga, ndi 30 mg. Mlingo uwu, mankhwalawa amayenera kumwa mwezi wonse wovomerezeka. Ngati 30 mg sikokwanira muyezo wa glycemia, mlingo umakulitsidwa mpaka 60, pambuyo mwezi wina - mpaka 90, ndiye - mpaka 120. Mapiritsi awiri, kapena 120 mg - mlingo waukulu, amaletsedwa kugwiritsa ntchito zochulukirapo patsiku. Ngati Diabeteson kuphatikizapo mankhwala ena ochepetsa shuga sangapereke shuga wabwinobwino wa matenda a shuga a 2, insulin imaperekedwa kwa wodwala.

Mimba komanso kuyamwa

Zomwe zimachitika chifukwa cha mankhwala osokoneza bongo kwa mwana wosabadwayo panthawi yoyembekezera amafufuzidwa mosalephera. Kuti mudziwe kuchuluka kwa chiwopsezo, gulu la FDA limagwiritsidwa ntchito nthawi zambiri. Mmenemo, zinthu zomwe zimagwira m'maguluwo zimagawika m'magulu molingana ndi momwe mluza umakhudzira. Pafupifupi kukonzekera konse kwa sulfonylurea ndi kalasi C. Kafukufuku wa nyama awonetsa kuti amatsogolera kukula kwa mwana kapena kumuyamwa. Komabe, zosintha zambiri ndizosintha, zomwe zimachitika posaberekanso sizinachitike. Chifukwa cha chiwopsezo chachikulu, palibe maphunziro aumunthu omwe adachitika.

Kafukufuku wokhudza kulowetsa kwa gliclazide mkaka wa m'mawere ndikulowetsa thupi la mwana sichinachitike, chifukwa chake, panthawi yoyamwitsa, odwala matenda ashuga satumizidwa.

Contraindication

Mndandanda wa zotsutsana potenga Diabeteson ndi mtundu wake:

1. Kufupika kwenikweni kwa insulin chifukwa cha kuwonongeka kwa maselo a beta mu mtundu 1 wa shuga kapena mtundu wachiwiri wa 2.
2. Zaka za ana. Mtundu wachiwiri wa matenda ashuga mwa ana ndi matenda osowa kwambiri, motero zotsatira za gliclazide pazinthu zomwe zikukula sizinaphunzire.
3. The kupezeka kwa khungu zimachitika chifukwa hypersensitivity kuti mapiritsi: zidzolo, kuyabwa.
4. Zomwe zimachitika payekha m'njira ya proteinuria ndi ululu wolumikizika.
5. Kuzindikira kochepa kwa mankhwalawa, komwe kumatha kuchitika kuyambira pachiyambipo cha makonzedwe, ndipo patapita kanthawi. Kuti muthane ndi gawo la chidwi, mutha kuyesa kukulitsa mlingo wake.
6. Zovuta za matenda ashuga: kwambiri ketoacidosis ndi ketoacidotic chikomokere. Pakadali pano, kusinthana ndi insulin ndikofunikira. Pambuyo pa chithandizo, Diabeteson amayambiranso.
7. Diabetesone imasweka m'chiwindi, kotero ndi kulephera kwa chiwindi simungathe kumwa.
8. Atagawa, mankhwalawa amachotseredwa ndi impso, motero sagwiritsidwa ntchito chifukwa cha nephropathy chifukwa cha kulephera kwaimpso. Kugwiritsa ntchito Diabeteson ndikololedwa ngati GFR sikugwa pansi pa 30.
9. Mowa wophatikiza ndi Diabetesone umawonjezera chiopsezo cha hypoglycemic coma, chifukwa chake mowa ndi mankhwala osokoneza bongo amaletsedwa.
10. Kugwiritsa ntchito miconazole, wothandizira antifungal, kumakulitsa kupanga insulin kwambiri ndipo kumathandizira kukulitsa kwambiri hypoglycemia. Miconazole silingatengedwe mapiritsi, kutumikiridwa mkati ndi kugwiritsa ntchito gel osakaniza pakamwa. Ma shampoos a Miconazole ndi mafuta akumkati amaloledwa. Ngati miconazole ikuyenera kugwiritsidwa ntchito, mlingo wa Diabeteson uyenera kuchepetsedwa kwakanthawi.

Zotsatira zoyipa za mankhwalawa

Chovuta chovuta kwambiri cha Diabetes pamthupi ndi hypoglycemia, chifukwa cha kusowa kwa chakudya chamagulu kapena mankhwala osokoneza bongo olondola. Ichi ndi chikhalidwe chomwe shuga imagwera pansi pa chitetezo. Hypoglycemia imayendera limodzi ndi zizindikiro: kunjenjemera kwamkati, kupweteka mutu, njala. Ngati shuga saukitsidwa munthawi yake, dongosolo lamanjenje la wodwalayo lingakhudzidwe. Chiwopsezo cha hypoglycemia mutatha kumwa mankhwalawa chimawonetsedwa pafupipafupi ndipo ndizosachepera 5%. Chifukwa cha kuchuluka kwachilengedwe komwe kumapangitsa Diabetes kukhala ndi insulin kaphatikizidwe, kuthekera kwa kuchepetsa koopsa kwa shuga kumakhala kotsika poyerekeza ndi kwa mankhwala ena omwe ali mgululi. Ngati mupitilira muyeso wokwanira 120 mg, kwambiri hypoglycemia imayamba, mpaka kukomoka ndi kufa.

Wodwala yemwe ali ndi vutoli amafunika kuchipatala mwachangu komanso glucose wolowa.

Zotsatira zina zosowa:

Ngati matenda ashuga adakhala ndi shuga kwa nthawi yayitali, kuwonongeka kwakanthawi kumawonekera pambuyo poyambitsa matenda a shuga. Nthawi zambiri, odwala amadandaula chophimba pamaso pa maso kapena chinyontho. Zotsatira zofananazi ndizofala kwambiri ndi kukonzanso kwa glycemia ndipo sizimatengera mtundu wa mapiritsi. Pakatha milungu ingapo, maso azolowera zinthu zatsopano, ndipo masomphenyawa adzabweranso. Pofuna kuchepetsa kugwa m'maso, mlingo wa mankhwalawa uyenera kuchuluka pang'onopang'ono, kuyambira ochepa.

Mankhwala ena osakanikirana ndi Diabetes angalimbikitse zotsatira zake:

• mankhwala onse odana ndi kutupa, makamaka phenylbutazone;
• fluconazole, mankhwala antifungal ochokera pagulu lomwelo ngati miconazole;
• ACE inhibitors - mankhwala ochepetsa kuthamanga kwa magazi, omwe nthawi zambiri amalembera shuga (Enalapril, Kapoten, Captopril, ndi ena otero);
• amatanthauza kuchepetsa acidity m'mimba thirakiti - famotidine, nizatidine ndi ena omaliza - thidine;
• streptocide, antibacterial othandizira;
• clarithromycin, maantibayotiki;
• antidepressants ofanana ndi monoamine oxidase zoletsa - moclobemide, selegiline.

Ndikofunika kuti m'malo mankhwalawa muthane ndi ena ndi zomwezi. Ngati sichingatheke m'malo mwanjira yolumikizira, muyenera kuchepetsa kuchuluka kwa odwala matenda ashuga komanso kuyeza shuga pafupipafupi.

Zitha kusintha

Diabeteson ndiko kukonzekera koyambirira kwa gliclazide, ufulu wokhala ndi dzina lagululi ndi wa kampani yaku France ya Servier. M'mayiko ena, amagulitsidwa pansi pa dzina la Diamicron MR. Diabeteson imaperekedwa ku Russia mwachindunji ku France kapena yopanga kampani yomwe ili ndi a Serier (pamenepa, wopanga Serdix LLC akuwonetsedwa pa phukusi, mapiritsi oterowo ndi apachiyambi).

Mankhwala ena onse omwe ali ndi vuto lomweli komanso mulingo womwewo ndi ma genetic. Mitundu yamagetsi imakhulupirira kuti sizikhala zothandiza nthawi zonse ngati zoyambirira. Ngakhale izi, zogulitsa zapakhomo zomwe zimakhala ndi gliclazide zimakhala ndi ndemanga zabwino za odwala ndipo zimagwiritsidwa ntchito kwambiri pothandizira matenda a shuga. Malinga ndi mankhwala, odwala nthawi zambiri amalandira mankhwala opangidwa ku Russia.

Analogs of Diabeteson MV:

Kodi odwala amafunsa chiyani?

Ndemanga ya Matenda Atiwowa

Mitengo yoyandikira

Mosasamala malo omwe akupanga ndi kipimo, mtengo wa kulongedza mapiritsi a Diabeteson MV apadera ndi ma ruble 310. Pamtengo wotsikirapo, mapiritsi amatha kugulidwa m'masitolo opezeka pa intaneti, koma ambiri aiwo muyenera kulipira kuti muperekenso.

Musanagwiritse ntchito mankhwalawa, onetsetsani kuti mwakumana ndi katswiri.