Ambiri ali ndi chidwi ndi momwe angatenge Metformin kuti akwaniritse njira zabwino zowonjezera zochizira.
Kuti muyankhe funsoli, muyenera kuphunzira momwe mungagwiritsire ntchito mankhwalawo mwatsatanetsatane ndikupeza malangizo kuchokera kwa endocrinologist.
Mankhwalawa amapezeka mu mawonekedwe a mapiritsi, omwe ali amitundu itatu kutengera mlingo: 500, 850 ndi 1000 mg. Chofunikira kwambiri chomwe chili mu mankhwalawo ndi metformin. Omwe amapangidwa ndi mankhwalawa ndi magnesium stearate, crospovidone, povidone K90, talc, wowuma chimanga.
Metformin, kapena metformin hydrochloride ndi woimira kalasi yayikulu, yomwe imathandizira kuthetsa hyperglycemia, ndiko kuti, kuwonjezeka kwa shuga m'magazi. Mankhwala oterewa amatengedwa makamaka ndi mtundu wachiwiri wa matenda ashuga. Mwambiri, wodwala yemwe amamwa mankhwalawa adzapulumutsidwa pazizindikiro za hypoglycemia, chifukwa njira zotsatirazi zizichitika mthupi:
- Kuchulukitsidwa kwa glucose ndi zotumphukira zimakhala.
- Kuchepetsa njira yogawa mafuta ndi mapuloteni.
- Mwadzidzidzi kaphatikizidwe ka shuga m'matumbo am'mimba ndikusintha kwake kukhala lactic acid.
- Kuletsa kumasulidwa kwa glycogen ku chiwindi.
- Kuthetsa insulin kukana.
- Kukondoweza kwa kuchuluka kwa shuga mu chiwindi.
- Kupereka cholesterol, komwe kumakomera boma la lipids.
Metformin ilibe gawo lililonse pakugwira ntchito kwa kapamba, yemwe amapanga insulin. Mankhwala sangayambitse hypoglycemia - kuchepa kwa kuchuluka kwa shuga m'magazi.
Malangizo ogwiritsira ntchito mankhwalawa
Musanagwiritse ntchito Metformin, muyenera kudziwa zomwe amagwiritsa ntchito.
Pankhaniyi, ndikwabwino kutsatira malingaliro a dokotala yemwe amapereka mankhwala, mukuganizira mawonekedwe a wodwala aliyense.
Zizindikiro zakupereka mankhwala ndi:
- matenda a shuga a mtundu woyamba ndi wachiwiri;
- prediabetes (mkhalapakati);
- kunenepa kwambiri ndi kuvutitsidwa kwa insulin;
- cleopolycystic ovary matenda;
- kagayidwe kachakudya matenda;
- pamasewera;
- kupewa kukalamba.
Ngakhale pali mndandanda wazambiri wazomwe mungamwe Metformin, nthawi zambiri imatengedwa ndi matenda a shuga a 2. Mu mtundu woyamba wamatenda, mankhwalawa amagwiritsidwa ntchito kawirikawiri, makamaka monga kuwonjezera kwa insulin.
Kafukufuku ambiri adawonetsa kuti ngakhale kumwa mankhwalawa nthawi yomweyo ndi jakisoni wa insulin, kufunika kwa mahomoni kumachepa pafupifupi 25-50%. Kuphatikiza apo, atatha kugwiritsa ntchito mankhwalawa kwa nthawi yayitali, kubwezeretsedwa kwa kagayidwe kazakudya kumatha bwino. Amagwiritsidwanso ntchito mumtundu wachiwiri wa shuga, womwe umafuna jakisoni wa insulin.
Mtundu wachiwiri wa matenda, Metformin amalembedwa pafupifupi pafupifupi chilichonse. Pa monotherapy, mlingo uyenera kuwonjezeka pang'onopang'ono. Chifukwa chake, poyamba amaloledwa kugwiritsa ntchito piritsi limodzi patsiku (500 kapena 850 mg). Ndikofunika kumwa mankhwalawa madzulo, koma kuti musasokoneze m'mimba, timalimbikitsidwa kumwa mapiritsi mukamadya chakudya kawiri patsiku - m'mawa ndi madzulo.
Popita nthawi, mlingo wa mankhwalawa ukhoza kuwonjezereka mwa kufunsa dokotala musanatero. Mlingo waukulu patsiku suyenera kupitilira 2.5 mg, ndiye kuti, wodwalayo amatha kumwa mapiritsi atatu patsiku. Pakatha milungu iwiri, kagayidwe kazakudya umayamba kubwerera mwakale. Pambuyo pakufika pamlingo wabwinobwino wamagazi, mulingo umatha kuchepetsedwa.
Kuphatikizidwa kwa mankhwalawa Metformin ndi sulfonylurea kumatha kubereka kwakanthawi kochepa. Koma thupi la munthu limazolowera kwambiri mankhwala amtunduwu. Chifukwa chake, monotherapy yokhala ndi Metformin imatha kukhala ndi tanthauzo losatha. Komabe, mu 66% ya anthu omwe ali ndi matenda ashuga, kuphatikiza kwa mankhwalawa kumapangitsanso kagayidwe kazachilengedwe.
Metformin imasungidwa pamtunda wosaposa 25 ° C kutali ndi ana. Alumali moyo wa mankhwala 3 zaka.
Contraindication ndi zoyipa
Musanayambe kumwa mankhwalawa, muyenera kuonetsetsa kuti angathe kumwa ndi wodwala. Monga mankhwala ena, Metformin ili ndi zotsutsana, monga:
- nthawi yobereka mwana;
- kuyamwitsa;
- zaka za ana mpaka zaka 10;
- uchidakwa wambiri;
- matenda a impso, chiwindi, mtima ndi kupuma dongosolo;
- matenda a shuga kapena kholo;
- m'mbuyomu lactic acidosis kapena kudziwiratu kwake;
- Zakudya zopatsa mphamvu zochepa;
- kuvulala kwam'mbuyomu komanso kulowererapo kwakukulu.
Ziyenera kuyang'ana pang'ono pa lactic acidosis - kudzikundikira kwa lactic acid. Zinthu zina zimatha kubweretsa kukula kapena kufalikira kwa lactic acidosis:
- Chifukwa, kuwonongeka kwaimpso, chifukwa, kulephera kupindika asidi;
- kuledzera kwa Mowa chifukwa cha uchidakwa wambiri;
- kulephera kwa mtima ndi kupuma;
- matenda a m'mapapo;
- matenda opatsirana omwe amachepetsa thupi - kusanza, kutsegula m'mimba, kutentha thupi;
- diabetesic ketoacidosis (kuphwanya chakudya cha metabolism);
- myocardial infaration.
Mankhwala osokoneza bongo omwe amapezeka molakwika amatha kuyambitsa zovuta zingapo kwa wodwala, mwachitsanzo:
- kugaya chakudya m'mimba - kusanza, kusanza, kutsegula m'mimba, kutsekemera kwazitsulo, kuchepa kapena kusowa kudya kwathunthu;
- thupi lawo siligwirizana - zotupa pakhungu ndi kuyabwa;
- lactic acid chikomaso ndichosowa, koma nthawi yomweyo zovuta zowopsa.
Kwenikweni, zovuta zoyipa zimangokhala zokha pakatha milungu iwiri atamwa mankhwalawo. Izi ndichifukwa choti mankhwalawa amalepheretsa kuyamwa kwa shuga m'matumbo. Zotsatira zake, chakudya chimayamba kuthiramo, zimayambitsa bata, kenako zizindikiro zina zosokoneza m'mimba. Nthawi zambiri thupi limazolowera mphamvu ya mankhwalawa, ndipo ngati zovuta sizovuta kuvomereza, ndiye kuti palibe chithandizo chamankhwala chomwe chikuyenera kuchitika.
Asanatenge Metformin, wodwalayo ayenera kufotokozera zonse zomwe zidakhalapo ndipo zilipo, popeza kubisala kwa chidziwitso chofunikira chotere kukhoza kuvulaza wodwala.
Kugwiritsa ntchito mankhwalawa kunenepa kwambiri
Anthu ambiri odwala matenda ashuga omwe ali ndi mtundu wachiwiri wa matendawa ndi onenepa kwambiri kapena wonenepa kwambiri.
Zikatero, kugwiritsa ntchito Metformin kumatha kukhala ndi zotsatirapo zabwino pakuchepetsa thupi kwa wodwalayo. Koma pofuna kuvulaza thupi lake, wodwala matenda ashuga ayenera kutsatira izi:
- Njira ya mankhwala sayenera kupitirira 22 masiku.
- Kumwa mapiritsi, wodwalayo ayenera kukhala ndi moyo wokangalika.
- Kumwa mankhwalawo kumayenderana ndi kumwa kwambiri.
- Chithandizo cha mankhwalawa chimalepheretsa wodwala kudya.
Tsiku lililonse, wodwala matenda ashuga ayenera kuchita zinthu zina zolimbitsa thupi, kaya zikuyenda, kuyenda, kusambira, volleyball, mpira wachinyamata ndi zina zambiri. Kuchokera muzakudya muyenera kupatula zinthu zophika buledi, makeke, chokoleti, kupanikizana, uchi, zipatso zotsekemera, zakudya zamafuta ndi zokazinga.
Dokotalayo amadzidalira payekha mlingo wa mankhwalawo. Sizingatheke kuti muzingochita nokha mankhwala chifukwa izi zimabweretsa zotsatirapo zoyipa. Itha kugwiritsidwanso ntchito ndi anthu omwe onenepa kwambiri, koma omwe amakhala okhuta.
Nthawi zambiri, kuchuluka kwa mankhwalawa kwa iwo kumacheperachepera.
Mtengo ndi fanizo la mankhwala
Mankhwalawa atha kugulidwa ku pharmacy iliyonse mumzinda kapena kuyitanidwa pa intaneti. Popeza Metformin imapangidwa ndi makampani osiyanasiyana apakhomo ndi akunja, mtengo wake umatha kusiyanasiyana.
Mwachitsanzo, ngati wopanga mankhwalawo ndi kampani yaku Russia, ndiye kuti mtengo wake, kutengera mlingo, ungakhale wa ma ruble 112 mpaka 305. Ngati wopangayo ali ku Poland, ndiye kuti mtengo wa mankhwalawo m'gawo la Russian Federation umachokera ku 140 mpaka 324 rubles. Mankhwalawa ndi ochokera ku Hungary m'dera la Russian Federation kuyambira 165 mpaka 345 ma ruble, kutengera kuchuluka kwa zinthu zomwe zikugwiritsidwa ntchito.
Mtengo wa mankhwalawo ndiolandilidwa kwa anthu omwe ali ndi ndalama zapakati komanso zochepa. Chifukwa chake, mankhwalawa amatha kusankhidwa potengera zochizira zomwe zikuyembekezeredwa komanso kuthekera kwachuma kwa ogula. Chifukwa chake, simungathe kulipira mankhwala okwera mtengo omwe angakhale ndi zotsatira zofanana ndi zotsika mtengo.
Popeza mankhwalawa amapangidwa m'maiko ambiri, amatha kukhala ndi ma synonyms ambiri, mwachitsanzo, Gliformin, Metfogamma, Bagomet, Formlinpliva ndi zina. Palinso mankhwala ena ofanana omwe amatha kumwa ngati Metformin pazifukwa zina sayenera kuchiza wodwala. Izi zikuphatikiza:
- Glucophage ndi mankhwala othandiza mankhwalawa matenda a shuga 2 komanso kunenepa kwambiri. Ili ndi katundu wa hypoglycemic. Kafukufukuyu akuwonetsa kuti kumwa mankhwalawa kumachepetsa kufa kwa anthu odwala matenda ashuga ndi 53%, kulowetsedwa myocardial - ndi 35%, stroke - ndi 39%. Mtengo wapakati (500 mg) ndi 166 ma ruble.
- Siofor ndi mankhwala ena abwino ochepetsa shuga m'magazi. Mbali yake ndiyakuti mankhwalawa amatha kuphatikizidwa ndi sulfonylureas, salicylates, insulin ndi ena. Chithandizo chokwanira chimasintha zotsatira zomwe zikuyembekezeka. Mtengo wapakati (500 mg) ndi ma ruble 253.
Odwala ambiri amadabwa kuti ndi mankhwala ati omwe amaposa. M'malo mwake, mankhwala ambiri amakhala ndi chinthu chogwira - metformin, kusiyana kumangokhala pazinthu zothandizira, chifukwa ali ndi zotsatira zofanananso ndi matenda a shuga.
Ndemanga za Odwala za Metformin
Ndemanga za kugwiritsa ntchito mankhwala a Metformin nthawi zambiri ndi zabwino.
Odwala ambiri omwe ali ndi matenda a shuga a 2 amawona kuchepa kwamphamvu kwa glucose kutsika mwazomwezo ndikuwasunga pamlingo womwewo.
Kuphatikiza apo, zabwino za chida ichi ndi:
- mawonekedwe osavuta a mapiritsi omwe ayenera kumeza ndi kutsukidwa ndi madzi;
- ntchito limachitika kamodzi kapena m'mawa ndi madzulo;
- m'malo otsika mtengo wa mankhwalawo.
Makasitomala ambiri adanenanso kuchepa thupi pamene akutenga Metformin. Koma nthawi yomweyo, muyenera kutsatira malamulo angapo: kusewera masewera, kutsatira zakudya, kumwa zamadzi zambiri, kudziletsa pakudya. Kuti muchite izi, muyenera kudya zipatso ndi ndiwo zamasamba, zakudya zopatsa mphamvu, zakudya zamafuta ambiri.
Nthawi zina mutha kupeza ndemanga zoyipa za odwala za mankhwalawa. Amaphatikizidwa makamaka ndi zotsatira zoyipa za mankhwalawa. Monga tanena kale, mavuto ambiri amachoka paokha pakatha milungu iwiri amalandira chithandizo, chifukwa thupi limazolowera zochita za metformin.
Metformin ndi mankhwala abwino kwambiri omwe amagwiritsidwa ntchito kuchepetsa matenda a shuga mu mtundu 1 komanso mtundu 2 wa matenda ashuga. Amagwiritsidwa ntchito ngati chowonjezera cha mankhwala a insulin, komanso monga mankhwala othandizira shuga ochulukitsa mu mtundu wachiwiri wa matenda. Musanagwiritse ntchito mankhwala, kufunsa dokotala ndikofunikira, komwe kumayang'ana zonse zokhala ndi contraindication ndikupereka mankhwala olondola.
Kuphatikiza apo, Metformin siyogulitsa popanda mankhwala. M'malo mwake, zotsutsana ndi zovuta za mankhwalawa ndizochepa, ndipo mawonekedwe ake ndi osowa kwambiri. Mwambiri, ndemanga za mankhwalawa ndi zabwino. Chifukwa chake, mankhwalawa amatha kuonedwa ngati osavulaza komanso othandiza.
Mulimonsemo, kugwiritsa ntchito mankhwala osokoneza bongo kuyenera kumayendera limodzi ndikuwonetsetsa kuchuluka kwa shuga pogwiritsa ntchito glucometer, zolimbitsa thupi komanso kupatula mafuta komanso zakudya zokazinga, makeke, maswiti azakudya. Pokhapokha kutsatira malamulo onsewa, wodwalayo amatha kukwaniritsa zotsatira zazitali za mankhwalawo ndikusunga kuchuluka kwa shuga m'magazi osiyanasiyana.
Malamulo ogwiritsa ntchito Metformin adzakambidwa mu kanema munkhaniyi.
