Siofor ndi mankhwala ogwiritsidwa ntchito pang'onopang'ono omwe amachepetsa shuga, amadziwika padziko lonse lapansi. Amagwiritsidwa ntchito osati odwala matenda ashuga okha, komanso mwa anthu omwe ali ndi chiwopsezo chachikulu cha matenda ashuga. Siofor imapangidwa ngati mapiritsi, omwe ali ndi 500-1000 mg ya metformin.
Kuphatikiza pa kuthira shuga, magazi amathandizanso m'njira zosiyanasiyana, zomwe zimaloleza kuti atenge kunenepa kwambiri, metabolic syndrome, mafuta a hepatosis, PCOS. Siofor ndi imodzi mwamankhwala otetezeka kwambiri pochiza matenda a metabolic. Mosiyana ndi mankhwala ena omwe amachepetsa shuga, sangayambitse hypoglycemia, samalimbikitsa kapangidwe ka insulin. Kutulutsa kofunikira kwambiri kwa Siofor ndi chiopsezo cha zotsatira zoyipa m'mimba.
Malangizo ogwiritsira ntchito
Siofor - ubongo wa kampani Berlin-Chemie, gawo la bungwe lodziwika bwino lazamankhwala lotchedwa Menarini. Mankhwala ndi Achijeremani kwathunthu, kuyambira gawo lopanga, kutha ndi ulamuliro womaliza. Pa msika waku Russia, adziyambitsa yekha njira yabwino komanso yotetezeka yolimbana ndi matenda ashuga komanso onenepa kwambiri. Chidwi ndi mankhwalawa zakula kwambiri posachedwa, pomwe zidapezeka kuti zili ndi zotsatira zingapo zopindulitsa thupi.
| The mapiritsi | Pulogalamu yogwira ntchito ndi metformin, kwa iye kuti mankhwalawo ali ndi mphamvu yochepetsera shuga. Mankhwalawa amakhalanso ndi zinthu zomwe zimathandizira kupanga mapiritsi ndikuwonjezera moyo wawo: - |
| Zochita pa thupi | Malinga ndi malangizo, Siofor amachepetsa shuga m'magazi pochita zinthu motsutsana ndi insulin komanso mapangidwe a shuga m'chiwindi. Kuchepetsa kudya kwa chakudya chamafuta, kumapangitsa kuti muchepetse kunenepa. Matenda a lipid metabolism: amachepetsa kuchuluka kwa triglycerides ndi cholesterol yoyipa m'magazi, osakhudza kuchuluka kwa lipoprotein yapamwamba kwambiri yothandiza mitsempha yamagazi. Pali maphunziro omwe akuwonetsa kuti Siofor amalimbikitsa kuyambika kwa ovulation ndi mimba mwa azimayi omwe ali ndi ovary ya polycystic, imatha kulepheretsa kukula kwa zotupa zina, kuchepetsa kutupa komanso kutalikitsa moyo. Kafukufuku wambiri akuchitika kuti atsimikizire kapena kutsutsa kusakhala ndi matenda ashuga a mankhwalawa. Chifukwa cha zotsatira zosatsutsidwa zomwe zimachitika pamwambapa, siziphatikizidwa ndi malangizo ogwiritsa ntchito. |
| Zizindikiro | Matenda a 2 a shuga, ngati zakudya zimasintha ndikulimbitsa thupi sikokwanira kukonza glycemia. Siofor imaphatikizidwa bwino ndi mankhwala ena ochepetsa shuga, nthawi zambiri imatengedwa ndi sulfonylureas. Kugwiritsa ntchito molumikizana ndi mankhwala a insulin kungachepetse kuchuluka kwa mahomoni ndi 17-30%, kumabweretsa kukhazikika kwa kuwonda kapena kuwonda. |
| Contraindication |
Siofor ndi mowa: uchidakwa woperewera kapena kuledzera kwa ethanol ndiko kuletsa kumwa mankhwalawo. |
| Mlingo | Mlingo woyambira wa odwala onse ndi 500 mg. Ngati mankhwalawa amalekeredwa bwino, amawonjezedwa pakatha masabata awiri ndi 500-1000 mg mpaka glycemia atakula. Mlingo woyenera kwambiri wa achikulire ndi 1000 mg katatu patsiku, kwa ana - 2000 mg, wogawidwa mu Mlingo wa 2-3. Ngati Siofor pa mlingo wololedwa wambiri sachepetsa shuga, mankhwala ochokera m'magulu ena kapena insulin amawonjezeredwa ku regimen yothandizira. Kuti muchepetse chiopsezo cha mavuto, mankhwalawa amawonjezeka bwino, mapiritsi omwera pamimba yonse. |
| Zotsatira zoyipa | Kubwezerani kwakukulu kwa Siofor ndi pafupipafupi kwambiri osakhala koopsa, koma m'malo mwake zosasangalatsa m'magawo am'mimba. Oposa 10% ya odwala matenda ashuga amakumana ndi mseru kumayambiriro kwa chithandizo. Kusungunula, kusokoneza kukoma, kupweteka kwam'mimba, kutsegula m'mimba ndikothekanso. Nthawi zambiri zosafunikira zimafooka, kenako zimazimiririka patatha milungu ingapo, koma nthawi zina zimatha kukhalabe kwa nthawi yonse yolamulira. Kutaya mtima, malangizo omwe amagwiritsidwira ntchito amatanthauzanso zovuta za Siofor, ngakhale kuti zimathandizira kuchepetsa thupi, zomwe nthawi zambiri zimakhala zofunika kwambiri m'matenda a shuga. Osakwana 0.01% ya odwala mukamamwa mankhwalawa amamva lactic acidosis, kuwonongeka kwa hepatic ntchito, ndi chifuwa. |
| Zambiri Zokhudza Lactic Acidosis | Magetsi ambiri a metformin m'magazi chifukwa cha bongo kapena kulephera kwaimpso kungapangitse kudzikundikira kwa lactic acid. Chiwopsezo chowonjezeka cha matenda ashuga, uchidakwa, njala, hypoxia. Lactic acidosis imafuna kuchipatala mwachangu. |
| Mimba ndi GV | Malangizo aku Russia Amaletsa kutenga Siofor panthawi yoyembekezera. Koma musadandaule ngati mwana wabadwa pa metformin. Malinga ndi asayansi aku Europe ndi ku China, mankhwalawa si owopsa kwa mayi ndi mwana wosabadwayo, chifukwa chake, amawerengedwa kuti ndi otetezeka (popanda chiopsezo cha hypoglycemia) m'malo mwa insulini. Ku Germany, azimayi 31% omwe ali ndi matenda osokoneza bongo amatenga metformin. |
| Kuyanjana kwa mankhwala osokoneza bongo | Ethanol, zinthu za radiopaque, zimawonjezera chiopsezo cha lactic acidosis. Mahomoni ena ndi ma antipsychotic, nicotinic acid amawonjezera shuga. Mankhwala a antihypertensive amatha kuchepetsa glycemia. |
| Bongo | Kuchuluka kwa mulingo woyenera komwe kumayendetsedwa ndi zakumwa zoledzeretsa, kumakulitsa chiopsezo cha lactic acidosis, koma sikuti kumayambitsa hypoglycemia. |
| Kusunga | Zaka zitatu pa kutentha pansi pa 25 ° C. |
Kukhazikitsidwa kwa Siofor sikumathetsa kufunika kwa kudya ndi masewera olimbitsa thupi. Odwala amalimbikitsidwa kuti azikhala ndi chakudya chopanda chakudya, kugawa kwawo koyenera kwa chakudya chambiri cha 6,6, ngati kuchepa kwa thupi kumafunikira - chakudya chomwe chili ndi zoperewera zama calorie.
Mitu ya mankhwalawa
Russia idakumana ndi zambiri pakugwiritsa ntchito Siofor pa matenda ashuga. Panthawi ina anali wotchuka kwambiri kuposa Glucophage woyambayo. Mtengo wa Siofor ndiwotsika, kuchokera ku 200 mpaka 350 ma ruble 60 mapiritsi 60, ndiye kuti palibe chifukwa chotenga zotsalira zotsika mtengo.
Matenda a shuga ndi kupsinjika kudzakhala chinthu chakale
- Matenda a shuga -95%
- Kuthetsa kwa mitsempha thrombosis - 70%
- Kuthetsa kwa kugunda kwamtima kwamphamvu -90%
- Kuthana ndi kuthamanga kwa magazi - 92%
- Kuwonjezeka kwa mphamvu masana, kukonza kugona usiku -97%
Mankhwala, omwe ali ndi fanizo la Siofor, mapiritsi amasiyana pamankhwala othandizira:
| Mankhwala | Dziko lopanga | Wopanga kampani | Mtengo wonyamula |
| Glucophage | France | Merk | 140-270 |
| Metfogamma | Germany | Farwag Pharma | 320-560 |
| Metformin MV Teva | Israeli | Teva | 150-260 |
| Glyformin | Russia | Akrikhin | 130-280 |
| Metformin Richter | Russia | AGideon Richter | 200-250 |
| Forethine | Russia | Mankhwala | 100-220 |
| Metformin Canon | Russia | Kupanga kwa Canonfarm | 140-210 |
Ma analogi onse ali ndi Mlingo wa 500, 850, 1000; Metformin Richter - 500 ndi 850 mg.
Siofor, ngakhale amadya, samachepetsa shuga, kusinthanitsa ndi analogues sikumveka. Izi zikutanthauza kuti matenda ashuga asamukira gawo lina, ndipo kapamba wayamba kusiya ntchito. Wodwalayo amapatsidwa mapiritsi omwe amathandizira kapangidwe ka insulin, kapena mahomoni a jakisoni.
Siofor kapena Glucofage
Dzina loyamba lazamalonda la Metformin kuti alandire patent anali Glucophage. Amawerengedwa ngati mankhwala oyamba. Siofor ndi wapamwamba kwambiri, wogwira ntchito mosiyanasiyana. Nthawi zambiri ma analogu nthawi zonse amakhala olakwika kuposa zoyambirira, pankhaniyi mkhalidwe umakhala wosiyana. Chifukwa cha kukwezedwa kwambiri komanso kulimbikitsa, Siofor adatha kukwaniritsa kuzindikira odwala matenda ashuga komanso endocrinologists. Tsopano amangoikidwa zochepa kwambiri kuposa Glucofage. Malinga ndi ndemanga, palibe kusiyana pakati pa mankhwala, onse mwangwiro amachepetsa shuga.
Kusiyanitsa kofunikira pakati pa mankhwalawa: Glucophage ali ndi mtundu wocheperako. Malinga ndi kafukufuku, mankhwala omwe atenga nthawi yayitali amatha kuchepetsa vuto la kugaya chakudya m'mimba, chifukwa chake, osalekerera bwino, mapiritsi a Siofor amatha kusinthidwa ndi Glucofage Long.
Siofor kapena Russian metformin
Nthawi zambiri, mankhwala aku Russia omwe ali ndi metformin amangokhala zofunikira. Mapiritsi ndi ma phukusi amapangidwa ndi kampani yanyumba, imapanganso zowongolera. Koma mankhwala, mankhwala omwewo, amagulitsidwa ku India ndi China. Popeza kuti mankhwalawa siotsika mtengo kwambiri kuposa Glucophage yoyambayo, kuwamwa sikupanga nzeru, ngakhale atadziwika kuti anali ndani.
Gwiritsani ntchito mwa anthu opanda shuga
Chifukwa cha multifactorial zotsatira zake komanso chitetezo chofanana, Siofor sichimatengedwa nthawi zonse cholinga chake - mankhwalawa. Katundu wa mankhwala kukhazikika, ndipo nthawi zina amachepetsa kukula, amakulolani kugwiritsa ntchito kuchepa thupi. Kafukufuku wofufuza akuwonetsa kuti zotsatira zabwino zimawonedwa mwa anthu omwe ali ndi metabolic syndrome ndi kuchuluka kwakukulu kwamafuta a visceral.
Kuphatikiza pa kuchuluka kwa kulemera, kuthekera kwa kutenga Siofor pochiza matenda otsatirawa kukuwunikiridwa:
- Ndi gout, Siofor amachepetsa mawonetseredwe a matendawa ndikuchepetsa kuchuluka kwa uric acid. Poyeserera, odwala adatenga 1,500 mg ya metformin kwa miyezi 6; kuwongolera kumawonedwa mu 80% ya milandu.
- Ndi mafuta a chiwindi, zotsatira zabwino za metformin zidadziwikanso, koma zomaliza sizinafotokozedwe. Pakadali pano, zakhazikika kuti mankhwalawa amawonjezera mphamvu ya zakudya zamafuta a hepatosis.
- Ndi polycystic ovary, mankhwalawa amagwiritsidwa ntchito kusintha ovulation ndikubwezeretsa kusamba.
- Pali malingaliro omwe metformin ikhoza kukhala ndi zotsutsana ndi khansa. Kafukufuku woyamba wawonetsa chiopsezo chochepetsa khansa ndi matenda ashuga a 2.
Ngakhale Siofor ali ndi zochepa zotsutsana ndipo amagulitsidwa popanda mankhwala, simuyenera kudzimvera. Metformin imangogwira bwino ntchito kwa odwala omwe ali ndi insulin kukana, chifukwa chake ndikofunika kuti ayesetse, osachepera glucose ndi insulin, ndikuwonetsa mulingo wa HOMA-IR.
- Onani >> Kuyesedwa kwa magazi kwa insulini - bwanji kuitenga ndi momwe mungachitire bwino?
Siofor ya kuwonda - momwe mungagwiritsire ntchito
Siofor imatha kutengedwa kuti muchepetse thupi osati kokha kwa odwala matenda ashuga, komanso kwa anthu athanzi labwino omwe ali onenepa kwambiri. Zotsatira za mankhwalawa zimatengera kuchepa kwa insulin. Zocheperako, ndikamachepetsa kwambiri insulini, minyewa yamafuta yake imaphwanyika. Pogwiritsa ntchito kulemera kwakukulu, kusuntha kochepa, kuperewera kwa zakudya m'thupi, kuperewera kwa insulin kupezeka pamlingo wina kapena wina mu zonse, kotero mutha kudalira kuti Siofor ithandizanso kutaya mapaundi owonjezera ochepa. Zotsatira zabwino amayembekezeka kwa anthu onenepa aamuna - pamimba ndi m'mbali, mafuta akulu amapezeka kuzungulira ziwalo, osati pansi pakhungu.
Umboni wa insulin kukokana ndi kuchuluka kwa insulin m'matumbo, komwe kumatsimikiziridwa ndi kusanthula kwa magazi a venous omwe amachitika pamimba yopanda kanthu. Mutha kupereka magazi mu labotale yamalonda iliyonse, kuchiritsa kwa dokotala sikofunikira pa izi. Pa fomu yomwe yaperekedwa, mfundo (zofunikira, zabwinobwino) ziyenera kuwonetsedwa zomwe mungayerekezere zotsatirazo.
Pulogalamu yoletsa matenda ashuga ku America yawonetsa kuti mapiritsi a Siofor amachepetsa kudya, motero amathandizira kuchepetsa thupi.
Amaganiziridwa kuti mankhwalawa amakhudza chisangalalo kuchokera kumbali zingapo:
- Zimakhudza kayendedwe ka kayendetsedwe ka chakudya ndi khunyu mu hypothalamus.
- Kuchulukitsa ndende ya leptin, mahomoni owongolera mphamvu zama metabolism.
- Amasintha kumva kwa insulin, chifukwa omwe ma cell amalandira mphamvu panthawi.
- Amalamulira mafuta kagayidwe.
- Mwina, amachotsa kulephera kwa mitsempha ya circadian, potero amatulutsa chimbudzi.
Musaiwale kuti poyamba pakhoza kukhala zovuta ndi kugaya chakudya. Thupi likazolowera, zizindikirozi ziyenera kusiya. Ngati palibe kusintha kwa masabata opitilira 2, yesani kusintha Siofor ndi metformin yayitali, mwachitsanzo, Glucofage Long. Pakakhala vuto la mankhwala osokoneza bongo, maphunziro olimbitsa thupi tsiku ndi tsiku komanso zakudya zama carb zotsika zingathandize kuthana ndi insulin.
Popanda contraindication, mankhwalawa amatha kumwa mosalekeza kwa nthawi yayitali. Mlingo mogwirizana ndi malangizo: kuyamba ndi 500 mg, pang'onopang'ono mupeze mlingo woyenera (1500-2000 mg). Lekani kumwa Siofor pamene cholinga chochepetsa thupi chikwaniritsidwa.
Malamulo Ovomerezeka
Mapiritsi a Siofor, oledzera pamimba yopanda kanthu, amawonjezera zovuta za kugaya, chifukwa chake amatengedwa panthawi ya chakudya kapena pambuyo pake, ndipo zakudya zochulukirapo zimasankhidwa. Ngati mulingo wocheperako, mapiritsi amatha kumwa kamodzi pa chakudya chamadzulo. Pa mlingo wa 2000 mg, Siofor amagawidwa pawiri.
Kutalika kwa mankhwala
Siofor amatenga momwe angafunikire. Ndi matenda a shuga, amamwa kwa zaka: woyamba yekha, ndiye ndi mankhwala ena ochepetsa shuga. Kugwiritsa ntchito metformin kwanthawi yayitali kungayambitse kuchepa kwa B12, chifukwa chake, odwala matenda ashuga amalimbikitsidwa kudya tsiku lililonse zakudya zopezeka ndi vitamini: ng'ombe ndi chiwindi cha nkhumba, nsomba zam'nyanja. Ndikofunika kuti pachaka chilichonse muzifufuza za cobalamin, ndipo ndikapanda kumwa, mumamwa vitamini.
Ngati mankhwalawa adatengedwa kuti alimbikitse ovulation, amathetsedwa nthawi yomweyo atatenga mimba. Ndi kuchepa thupi - mankhwalawa akayamba mphamvu. Ngati zakudya zimatsatiridwa, nthawi zambiri theka la chaka limakhala lokwanira.
Mulingo woyenera
Mlingo woyenera wa anthu odwala matenda ashuga amaonedwa kuti ndi 2000 mg wa metformin, popeza kuchuluka kotero kumadziwika ndi kuchuluka kwabwino kwa "shuga-kutsitsa zotsatira - zotsatira zoyipa." Kafukufuku wonena za mphamvu ya Siofor pazakudya zinachitika ndi 1500 mg ya metformin. Popanda chiopsezo chathanzi, mlingo umatha kuwonjezeka mpaka 3000 mg, koma muyenera kukonzekera kuti zovuta zam'mimba zitha kuchitika.
Kuyenderana ndi mowa
Malangizo a mankhwalawa akunena za kulephera kudziletsa kwa mowa pachimake, chifukwa zingayambitse lactic acidosis. Pankhaniyi, milingo yaying'ono yofanana ndi 20-40 g ya mowa imaloledwa. Musaiwale kuti Mowa umapangitsa kubwezeretsa shuga.
Zokhudza chiwindi
Zochita za Siofor zimakhudzanso chiwindi. Amachepetsa kaphatikizidwe ka glucose kuchokera ku glycogen ndi mankhwala osagwiritsidwa ntchito m'thupi. Kuchuluka kwa izi kumakhala kotetezeka kwa thupi. Nthawi zina, ntchito ya chiwindi michere imachulukana, chiwindi chimayamba. Mukasiya kutenga Siofor, zolakwika zonse ziwiri zimapita zokha.
Ngati matenda a chiwindi samatsatiridwa ndi kuperewera, metformin imaloledwa, ndipo ndi mafuta hepatosis amathandizidwanso kuti agwiritsidwe ntchito. Mankhwala amaletsa makutidwe ndi okosijeni a lipids, amachepetsa kuchuluka kwa triglycerides ndi cholesterol, amachepetsa kudya kwamafuta m'chiwindi.Malinga ndi kafukufuku, katatu nthawi kumawonjezera mphamvu ya zakudya zomwe zimaperekedwa kwa mafuta hepatosis.
Ndemanga
Amakhala kuti Siofor amalembedwa kuti azingotengedwa pokhapokha zakudya sizikuyenda bwino, zomwe zikuwonetsa kusokonekera kwa mahomoni. Onetsetsani kuti mukuyesa mayeso a mahomoni ndikuwapatsa mapiritsi kuti mufotokozeretse momwe zakhudzidwira zakumaso. Ndipo Siofor amangothandiza kusuntha njira yochepetsera thupi kuchokera kumanda wakufa ndikuwonjezera pang'ono zotsatira za zakudya.
