Insulin ndi timadzi tomwe timatulutsa kapamba. Amatengako mbali zosiyanasiyana zama metabolic ndipo amachititsa kuti thupi lizikhala ndi mphamvu zambiri.
Popanda kupanga, matenda a shuga 1 amayamba ndipo, ngati simuyamba jakisoni, inshuwaransi imakumana ndi imfa. Mtundu wachiwiri wa matenda ashuga, kupanga insulini kumakhala kwabwinobwino kapenanso kukweza, koma minyewa sikumazindikira. Zikatero, insulin ndi yoyipa, kayendetsedwe kake sikunawonetsedwa komanso koopsa.
Kuonjezera insulin m'magazi kungayambitse kukula kwa kotchedwa metabolic syndrome - kunenepa kwambiri, kuthamanga kwa magazi, cholesterol yowonjezera, mafuta ndi glucose m'magazi. Mavuto omwewo akhoza kutsagana ndi kuperekedwa kwa insulin popanda kuwonetsa - mwachitsanzo, kukula kwa minofu mu othamanga.
Makhalidwe ofunikira a insulin
Kutulutsidwa kwa insulini kumachitika pamene glucose alowa m'magazi, ndiye kuti chakudya chilichonse chimakhala chothandizira kutulutsa kwa timadzi timeneti.
Nthawi zambiri, zimatsimikizira kuperekera kwa michere m'maselo, omwe amapereka momwe zakhalira.
Mu thupi, insulini imagwira ntchito zingapo zomwe zimatsimikizira ntchito yofunika. Ubwino wa insulin m'thupi umaonekera mwa izi:
- Amachepetsa kuchuluka kwa shuga m'magazi ndikuwonjezera kuyamwa kwake ndi maselo.
- Zimawonjezera kukula kwa minofu ndikulimbikitsa kupanga kwa mapuloteni m'maselo.
- Zimalepheretsa kuchepa kwa minofu.
- Amanyamula amino acid kumisempha minofu.
- Imathandizira kutuluka kwa potaziyamu, magnesium ndi phosphate m'maselo.
- Imalimbikitsa kapangidwe ka glycogen m'chiwindi.
Zokhudza insulin pa mafuta kagayidwe
Phunziro lomwe limaphunziridwa kwambiri ndi insulin polimbana ndi mavuto a kagayidwe ka mafuta. Zimayambitsa kukulitsa kunenepa kwambiri, komwe kulemera kumachepetsedwa ndikuvuta kwambiri.
Kukhazikika kwa mafuta m'chiwindi kumayambitsa mafuta a hepatosis - kuchuluka kwa mafuta mkati mwa khungu la chiwindi, kutsatiridwa ndi kulowetsedwa ndi minofu yolumikizana ndikukula kwa chiwindi cholephera. Miyala ya cholesterol imapangidwa mu ndulu, zomwe zimayambitsa kuphwanya kwa mapangidwe a bile.
Kukhazikika kwa mafuta mu mafuta amkati amapanga mtundu wapadera wa kunenepa kwambiri - kufalikira kwa mafuta m'mimba. Mtundu wamafuta onenepa amadziwika ndi chidwi chochepa chakudya. Mothandizidwa ndi insulin, kupanga sebum kumapangidwira, ma pores pa nkhope amakula, ziphuphu zimayamba.
Njira zoyipa zochitira zinthu zotere zimachitika m'njira zingapo:
- Enzime ya lipase imatsekedwa, yomwe imaphwanya mafuta.
- Insulin siyilola kuti mafuta asandulike mphamvu, chifukwa amathandizira pakuphatikizana kwa glucose. Mafuta amakhalabe odzikundikira.
- Mu chiwindi, mothandizidwa ndi insulin, kaphatikizidwe wamafuta acids amathandizidwa, zomwe zimapangitsa kuti mafuta azikhala m'maselo a chiwindi.
- Pansi pa kuchitapo kwake, kulowa kwa glucose m'maselo a mafuta kumawonjezeka.
- Insulin imalimbikitsa kaphatikizidwe ka cholesterol ndikuletsa kupasuka kwake ndi ma asidi a bile.
Zotsatira zamachitidwe amtunduwu m'magazi, mafuta ochulukitsa kwambiri amawonjezeka, ndipo amawaika pamakoma a mitsempha - atherosulinosis imayamba. Kuphatikiza apo, insulin imathandizira kuchepetsedwa kwa lumen ya mitsempha ya magazi, yolimbikitsa kukula kwa minofu minofu khoma lamitsempha. Zimalepheretsanso kuwonongeka kwa magazi omwe amabisa chotengera.
Ndi atherosclerosis, matenda amtima amayamba, minyewa yaubongo imakhudzidwa ndikukula kwa mikwingwirima, matenda oopsa oopsa amachitika, ndipo ntchito ya impso imasokonekera.
Zotsatira za kuchuluka kwa insulin m'mwazi
Insulin ndi othandizira kukula kwa minofu, zomwe zimapangitsa kuti magawo a cell achulukane. Ndi kuchepa kwamphamvu kwa insulin, chiopsezo cha zotupa zam'mawere zimawonjezeka, pomwe chimodzi mwazinthu zowopsa ndizovuta zamtundu wamtundu wa matenda ashuga a 2 ndi mafuta a m'magazi ambiri, ndipo monga mukudziwa, kunenepa kwambiri komanso matenda a shuga nthawi zonse zimayendera limodzi.
Kuphatikiza apo, insulin ndiyo imayang'anira kusungidwa kwa magnesium mkati mwa maselo. Magnesium ali ndi katundu wopumula khoma lamitsempha. Ngati kuphwanya kwamphamvu kwa insulin, magnesium imayamba kuchotsedwa m'thupi, ndipo sodium, m'malo mwake, imachedwa, zomwe zimayambitsa kuchepa kwamitsempha yamagazi.
Udindo wa insulini pakukula kwa matenda angapo umatsimikiziridwa, pomwe, posakhala chifukwa chawo, umapanga nyengo zoyenera:
- Matenda oopsa.
- Matenda a oncological.
- Njira zopweteketsa matenda.
- Matenda a Alzheimer's.
- Myopia.
- Matenda oopsa a ubongo amayamba chifukwa cha insulin pa impso ndi mitsempha. Nthawi zambiri, pansi pa insulin, vasodilation imachitika, koma zikhalidwe la kutaya chidwi, dipatimenti yachifundo yokhudzana ndi mantha imayendetsedwa ndipo ziwiya zimachepetsedwa, zomwe zimayambitsa kuthamanga kwa magazi.
- Insulin imathandizira kupanga zotupa - ma enzymes omwe amathandizira njira yotupa ndipo amalepheretsa kaphatikizidwe ka adiponectin ya mahomoni, omwe ali ndi anti-yotupa.
- Pali maphunziro omwe akuwonetsa gawo la insulin pakukula kwa matenda a Alzheimer's. Malinga ndi lingaliro lina, puloteni wapadera amapangidwa m'thupi lomwe limateteza maselo muubongo kuti atulutsidwe ndi minyewa ya amyloid. Ndizinthu izi - amyloid, zomwe zimapangitsa kuti ma cell a ubongo atha kugwira ntchito yawo.
Mapuloteni omwewo amateteza kuchuluka kwa insulin m'magazi. Chifukwa chake, pakuwonjezeka kwa insulin, mphamvu zonse zimagwiritsidwa ntchito pakuchepa kwake ndipo ubongo umakhalabe wopanda chitetezo.
Kuzama kwambiri kwa insulin m'magazi kumayambitsa kukoka kwa diso, komwe kumachepetsa kuthekera kwazowoneka bwino.
Kuphatikiza apo, pakhala kupitapo pafupipafupi kwa myopia mu mtundu 2 wa matenda a shuga komanso kunenepa kwambiri.
Momwe mungakulitsire chidwi cha minofu
Popewa kukula kwa metabolic syndrome, malingaliro otsatirawa akuyenera kuonedwa:
- Kuletsedwa kwa chakudya chamafuta ambiri mu mafuta m'thupi (nyama yamafuta, mafuta amphumo, mafuta anyama, chakudya chofulumira).
- Kuchepetsa kudya zamafuta ochepa mthupi mwa kuchotsa shuga konse muzakudya zanu.
- Chakudyacho chiyenera kukhala chamagulu, popeza kupanga kwa insulin sikukhudzidwa kokha ndi chakudya, komanso mapuloteni.
- Kugwirizana ndi zakudya komanso kusapezeka kwa zokhwasula-khwasula, makamaka ndi shuga.
- Chakudya chotsiriza chimayenera kukhala maola 4 asanagone, popeza chakudya chamasana chimakwiyitsa insulini ndikuvulaza mawonekedwe a mafuta.
- Ndi kuchuluka kwa thupi, kugwira masiku osala kudya komanso kusala kudya kwakanthawi (kokha kuyang'aniridwa ndi dokotala).
- Kuyambitsa zakudya zamagulu okhala ndi fiber yokwanira.
- Zochita zolimbitsa thupi moyenera ngati mukuyenda tsiku ndi tsiku kapena kuchitira zolimbitsa thupi.
- Kukhazikitsidwa kwa kukonzekera kwa insulin kungakhale pokhapokha kupanga - ndi mtundu wa 1 shuga mellitus, nthawi zina zonsezi zimabweretsa kukula kwa matenda a metabolic.
- Ndi mankhwala a insulin, kuwunika pafupipafupi kuchuluka kwa shuga ndikofunikira kupewa bongo.
Pali zikhulupiriro zambiri zabodza zomwe zimazungulira insulin - mu kanema munkhaniyi adzatsutsidwa bwino.
